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Perceptions of Older Adults with Hematological Cancer on Diet and Exercise Behavior and Its Role in Navigating Daily Tasks.

Diet and exercise are associated with the maintenance of physical function, independence and better health-related quality of life in cancer survivors. Adherence to healthy diet and exercise guidelines, however, remains low. The aim of this study was to explore the perceptions of hematological cancer survivors (HCS, ≥50 years) on the role of diet and exercise in navigating daily tasks using a qualitative descriptive research method. Eligible HCS completed an online survey gathering demographic information including physical functioning, exercise frequency, malnutrition and frailty risk. Follow

Medication Experience and Adherence to Oral Chemotherapy: A Qualitative Study of Patients' and Health Professionals' Perspectives.

Lack of adherence constitutes one of the most important challenges in patients undergoing treatment with oral antineoplastic drugs (ANEO). Understanding cancer patients' experiences with respect to their medication is key for optimizing adherence and therapeutic results. We aimed to assess the medication experience (ME) in patients with cancer in treatment with ANEO, to describe the barriers and facilitators related to the disease and its treatment and to compare them with the healthcare professionals' perspectives. We carried out an exploratory qualitative study in the University Hospital of

Use of Complementary Traditional Chinese Medicines by Adult Cancer Patients in Taiwan: A Nationwide Population-Based Study.

BACKGROUND: Many patients with cancer seek complementary and alternative medicine treatments. We investigated the use of traditional Chinese medicine (TCM) by adult cancer patients in Taiwan. METHODS: We reviewed the Registry for Catastrophic Illness Patients Database of Taiwan, and included all adult patients diagnosed cancer, based on the International Classification of Diseases (ninth revision), from 2001 to 2009 and followed until 2011. This database allowed categorization of patients as TCM users (n = 74 620) or non-TCM users (n = 508 179). All demographic and clinical claims data were a

Effectiveness of bilingual health education on obesity and dietary behaviors in Mongolian adolescents: a six-month intervention study.

BackgroundObesity among adolescents has become a global public health concern. Previous studies have shown that multidimensional interventions, such as school-based programs, health education, and guidance on diet and physical activity, effectively improve obesity in adolescents. However, there is a lack of research on bilingual health education interventions in minority language environments in rural and pastoral areas of China. Based on a 2023 field survey of students from three Mongolian middle schools in Ar Horqin Banner, Chifeng City, Inner Mongolia, this study evaluated the effect of a 6

Frail older adults' challenges in using telehealth services: A scoping review.

ObjectiveTelehealth is increasingly used to expand access to healthcare, but rapid digitalization risks exacerbating exclusion among frail older adults, who often face intersecting limitations related to health, resources, and digital competence. As this group frequently has complex care needs, mapping their experiences is essential to ensure equitable access to digital care. The aim was to map the challenges frail older adults experience when using telehealth services.MethodsThis scoping review followed Arksey and O'Malley's framework and PRISMA-ScR guidelines. PubMed, CINAHL, Scopus, and Web

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… The study was conducted at a retirement community with assisted living and independent living sections. | 29 older adults (mean age 88 years) 17 in assisted living and 12 in independent living; approximately half in each setting moved to the facility due to age-related decline or medical illness. …

Clinical and health economic impact of isavuconazole for treatment of invasive aspergillosis and mucormycosis: a retrospective, matched multicentre cohort study in Germany.

PURPOSE: Isavuconazole is effective against invasive aspergillosis (IA) and mucormycosis (IM) and may improve clinical outcomes compared to alternative antifungal treatments. However, real-world evidence regarding its clinical use and the health economic burden of inpatient treatment for IA and IM of patients with haematological malignancies remains limited. METHODS: A retrospective, matched, multicentre cohort study was conducted in six German tertiary care centres. The study included adults with haematological or oncological diseases who were diagnosed with proven, probable, or possible IA

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… Indirect costs, such as productivity losses due to illness related disability or death before retirement age, were excluded from the analysis due to the severity of haematological and oncological diseases. Statistical analysis RStudio version 4.5.0 (from 2025-04-11) was used for data analysis. …

Упражнения и питание в гематологических заболеваниях: свидетельства перевода и новые меры вмешательства.

Пациенты, страдающие гематологическими микроорганизмами, включая лейкемию, лимфому и миелому, живут дольше из - за прогресса в лечении. Тем не менее такое лечение часто приводит к токсичным последствиям, влияющим на качество жизни пациентов (QoL). Хотя мероприятия, связанные с образом жизни, такие, как упражнение и питание, приносят пользу, снижая риск заболевания раком и улучшая результаты лечения твердых опухолей, их применение в гематологических опухолей по-прежнему недостаточно изучено. В настоящем описательном обзоре рассматриваются текущие данные о роли физических упражнений и питания в

Global burden and regional inequalities of cancer in older adults from 1990 to 2021 and its projection until 2050.

BackgroundGlobal ageing will further exacerbate the cancer burden, and the intersection of cancer and ageing represents an emerging and significant global public health challenge.MethodsBased on the Global Burden of Disease 2021 (GBD 2021) data, we utilized the estimated annual percentage change and Joinpoint regression model to examine the temporal trends in the global cancer burden among elderly population from 1990 to 2021. Pearson's rank correlation analysis was conducted to assess the relationship between disease burden and the socio-demographic index (SDI). Furthermore, an autoregressive

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… The United States is currently experiencing a demographic and health transition characterized by rapid population aging, particularly due to the aging of baby boomers (those born between 1946 and 1964), who are reaching retirement age and living longer than previous generations [ 24 ]. …

Disparities in clinical trial participation among older adult Medicare beneficiaries with hematologic malignancies from 2006 to 2019: A SEER-Medicare analysis.

BACKGROUND: Clinical trials (CTs) are essential for expanding treatment options across hematologic malignancies (HM) and providing access to novel treatments. However, older adults with HM are often underrepresented in CTs, and a national-level evaluation of factors influencing their participation is lacking. METHODS: The authors conducted a retrospective cohort study using the Surveillance, Epidemiology, and End Results (SEER)-Medicare database, identifying patients ≥66 years old diagnosed with HM between 2006 and 2018 (follow-up to December 2019). CT participation was defined by Medicare cl

Analyzing Comorbidity Patterns in Patients With Thyroid Disease Using Large-Scale Electronic Medical Records: Network-Based Retrospective Observational Study.

BackgroundThyroid disease (TD) is a prominent endocrine disorder that raises global health concerns; however, its comorbidity patterns remain unclear.ObjectiveThis study aims to apply a network-based method to comprehensively analyze the comorbidity patterns of TD using large-scale real-world health data.MethodsIn this retrospective observational study, we extracted the comorbidities of adult patients with TD from both private and public data sets. All comorbidities were identified using ICD-10 (International Classification of Diseases, 10th Revision) codes at the 3-digit level, and those with

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… Comorbidity and functional trajectories from midlife to old age: the Health and Retirement Study. J Gerontol A Biol Sci Med Sci. 2015 Mar 1;70(3):332–338. doi: 10.1093/gerona/glu113. https://europepmc.org/abstract/MED/25060316 .glu113 34. Lam A. …

Individualized Hospital to Home, Exercise-Nutrition Self-Managed Intervention for Pre-Frail and Frail Hospitalized Older Adults: The INDEPENDENCE Randomized Controlled Pilot Trial.

PurposePre-frailty and frailty in older adults are associated with poor health outcomes and increase health-care costs, and further worsening during hospitalization. This study aimed to examine the effect of an individualized hospital to home, exercise-nutrition self-managed intervention for pre-frail and frail hospitalized older adults.Patients and methodsOlder adults admitted to an acute medical unit of a tertiary hospital in South Australia who were pre-frail or frail were recruited from September 2020 to June 2021, randomized to either control or intervention group and followed up at 3 and

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… INDEPENDENCE, INDividualized therapy for Elderly Patients using Exercise and Nutrition to reduce depenDENCE post discharge; MMSE, mini-mental state examination; PG-SGA, Patient-Generated Subjective Global Assessment; SALHN, Southern Adelaide Local Health Network; SHARE-FI, Survey of Health Ageing and Retirement …

Treatment decision making (TDM): a qualitative study exploring the perspectives of patients with chronic haematological cancers.

OBJECTIVES: Haematological malignancies are the fifth most common cancer in the UK, with chronic subtypes comprising around a third of all new diagnoses. These complex diseases have some similarities with other cancers, but often require different management. Surgical resection is not possible, and while some are curable with intensive chemotherapy, most indolent subtypes are managed with non-aggressive intermittent or continuous treatment, often over many years. Little is known about the views of patients with chronic haematological cancers regarding treatment decision making (TDM), a deficit

Irish Endocrine Society 44th Annual Meeting.

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… The psychosocial impact of frailty among people with diabetes: findings from the Study of Health Aging and Retirement in Europe (SHARE). … Data from 21 countries included in the Survey of Health, Ageing and Retirement in Europe were analysed. Depression and QOL were defined using the 12-item EURO-D index (cut-off ≥ 4) and CASP-12 index (cut-off < 35), respectively. Frailty was measured using the frailty phenotype. …

The BNP-to-Albumin Ratio (BAR) as a Predictor of All-Cause Mortality in Elderly Patients with Atrial Fibrillation.

BackgroundThis study aimed to evaluate the prognostic value of the BNP-to-albumin ratio (BAR) for all-cause mortality in AF patients aged ≥60 years.MethodsThis single-center retrospective study included clinical data from 1458 AF patients treated at the First Affiliated Hospital of Kunming Medical University between December 2019 and December 2023. Using the optimal cutoff value determined by the restricted cubic spline, patients were divided into a low BAR group (BAR ResultsThe study ultimately included 842 patients with AF. Kaplan‒Meier analysis revealed that among elderly AF patients, the a

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… The relationship between C-reactive protein-triglyceride-glucose index and cardiovascular disease: insights from the China health and retirement longitudinal study (CHARLS) . Cardiovasc Diabetol . 2025 ; 24 ( 1 ): 410 . doi: 10.1186/s12933-025-02960-w PMC12560464 41152893 39. …

Повышение уровня информированности и знаний о раке в Йоханнесбурге и округах iLembe с помощью целенаправленных просветительских мероприятий на уровне общин: экспериментальное исследование.

В Южной Африке рак по-прежнему вызывает все большую озабоченность в области общественного здравоохранения, особенно в недостаточно обслуживаемых общинах, где различия в уровне информированности и доступе к медицинскому обслуживанию приводят к задержкам в диагностике. В рамках этого исследования была проведена оценка воздействия ориентированной на культурные особенности просветительской деятельности на основе адаптированного модуля исследований и просвещения по вопросам доступа к информации о раковых заболеваниях (c-CARE) в районах Йоханнесбурга и iLembe. Было проведено экспериментальное исслед

Technology forecast: advanced therapies in late clinical research, EMA approval or clinical application via hospital exemption.

Background: The umbrella term ATMPs (Advanced Therapy Medicinal Products) comprises cell therapies, gene therapeutics and tissue engineered products. After implementation of the Regulation 1394/2007, only a couple of products have obtained a centralized European marketing authorisation. Objectives: The aim of the presented study is to give an overview on ATMPs available within the European Union either via centralized marketing authorisation or via national Hospital exemption. Additionally, a forecast on innovative ATMPs in the process of EMA approval as well as in phase III and IV clinical tr

Effect of a community-based nursing intervention on mortality in chronically ill older adults: a randomized controlled trial.

BackgroundImproving the health of chronically ill older adults is a major challenge facing modern health care systems. A community-based nursing intervention developed by Health Quality Partners (HQP) was one of 15 different models of care coordination tested in randomized controlled trials within the Medicare Coordinated Care Demonstration (MCCD), a national US study. Evaluation of the HQP program began in 2002. The study reported here was designed to evaluate the survival impact of the HQP program versus usual care up to five years post-enrollment.Methods and findingsHQP enrolled 1,736 adult

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… The 15 organizations that implemented programs in the MCCD were also diverse and included four commercial disease management vendors, three hospitals, three academic medical centers, one integrated delivery system, one hospice program, one long-term care facility, one retirement community, and one health …

Каталоги оценок показателей качества жизни, связанных с здоровьем, по шкале EQ-5D-3L для 199 хронических заболеваний и рисков здоровья для использования в Великобритании и США.

СВОДНАЯ ИНФОРМАЦИЯ: В экономической оценке важное значение имеют связанные со здоровьем показатели качества жизни (HRQOL), однако в некоторых случаях отсутствуют первичные источники и требуется информация из вторичных источников. Существующие каталоги HRQOL Соединенного Королевства/США основаны, в частности, на предыдущих системах классификации диагнозов. Недавно опубликованный датский каталог объединился EQ-5D-3L Данные национальных обследований в области здравоохранения с использованием национальных регистров, содержащих информацию о пациентах ICD-10 - диагностика, медицинское обслуживание и

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… 0.0020 0.777 0.827 1 2nd quartile 14.244 47.4 2.1 0.0240 0.818 0.0023 0.727 0.848 1 0.861 0.0016 0.810 0.844 1 3rd quartile 14.247 44.3 1.6 0.0196 0.860 0.0018 0.796 1 1 0.891 0.0013 0.827 1 1 4th quartile 14.247 47.6 1.6 0.0183 0.879 0.0016 0.796 1 1 0.905 0.0012 0.827 1 1 Socio-economic position Retired … , age 12,408 74.9 4.3 0.0325 0.750 0.0028 0.691 0.796 0 0.812 0.0020 0.777 0.827 1 Retirement, free 2414 63.1 2.7 0.0545 0.839 0.0042 0.760 0.796 1 0.874 0.0030 0.816 0.827 1 Early retirement, health reasons 2227 52.1 4.7 0.0778 0.547 0.0079 0.255 0.689 0.76 0.674 0.0053 0.506 0.767 0.816 Seek leave …

Strategies for promoting exercise adherence within a cancer exercise recovery program: a qualitative case study.

BACKGROUND: Physical activity (PA) plays an important role in physical health and well-being for cancer survivors. However, cancer survivors demonstrate low adherence to cancer PA guidelines. Research is needed to understand how to optimize delivery of cancer PA programs to enhance participation and adherence. In this study, we conducted an instrumental qualitative case study of a clinical cancer exercise recovery program (CERP) demonstrating high adherence (over 90% session completion), with the goal of understanding implementation strategies that patients link to higher program adherence. ME

Fear of cancer recurrence and associated factors in family caregivers of patients with hematologic malignancy receiving chemotherapy: A latent profile analysis.

ObjectiveThis study identified the potential subgroups of fear of cancer recurrence (FCR) in family caregivers (FCs) of patients with hematologic malignancies receiving chemotherapy, as well as exploring factors associated with subgroups.MethodsThis was a cross-sectional study involving 206 pairs of participating patients with hematologic malignancies receiving chemotherapy and their FCs. Using Mplus 8.3 to perform the latent profile analysis of FCs' FCR, the FCs' burden, quality of life, psychological resilience, and anxiety as well as their demographic characteristics were compared between t

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… The FCs in this study were predominantly middle-aged to elderly individuals and were spouses of hematologic malignancy patients who were facing retirement and did not experience significant work pressure or family burden. …