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Multidisciplinary rehabilitation and eye tracker-assisted communication in locked-in syndrome: a case report and literature review.

BACKGROUND: Locked-in syndrome (LIS) is a rare and severe neurological condition characterized by quadriplegia and anarthria with preserved consciousness. Communication impairment is a major barrier to psychosocial adaptation and long-term rehabilitation. A new rehabilitation strategy is needed to restore multi-sensory impairments. CASE PRESENTATION: A patient underwent eye tracker therapy as part of a comprehensive multidisciplinary rehabilitation program following the diagnosis of LIS, which aimed to improve ocular scanning and gaze patterns to enable the patient to communicate using ocular…

Single-cell analysis reveals impaired Müller glia-mediated intercellular communication and photoreceptor pathology in USH1C retinal organoids.

Usher syndrome type 1, caused by pathogenic variants in the USH1C gene, leads to congenital deafness and progressive retinal degeneration re … ations in cell adhesion and canonical Wnt signaling in Müller glia cells. Analysis of intercellular communication revealed an overall reduced signaling efficiency, particularly affecting Müller glia-mediated retinal adhesion processes. Morphological characterization of organoids confirmed transcriptome changes by showing degeneration of the outer limiting membr …

Bacterial small RNAs and extracellular vesicles in inflammatory and osteoimmune diseases: regulatory mechanisms and host-microbe communication.

Bacterial small RNAs (sRNAs) functions as post-transcriptional regulators that influnce microbial adaptation, pathobiont behavior, and host-microbe communication. This review analyzes bacterial sRNAs and vesicle-associated RNA signals in inflammatory and osteoimmune diseases, with a focus on gastrointestinal and oral microbial communities. Major sRNA classes and mechanisms are summarized, followed by an evaluation of evidence in gastrointestinal inflammation, periodontitis, rheumatoid arthritis, osteoarthritis, and postmenopausal osteoporosis. Direct disease-related evidence is currently limit…

Emphysematous pyelonephritis with perinephric extension and fistulous communication to the descending colon: a rare CT imaging diagnosis.

Emphysematous pyelonephritis (EPN) is a severe necrotizing infection characterized by gas formation within the renal parenchyma and surrounding tissues. Although perinephric extension is well recognized, fistulous communication with the adjacent bowel is exceedingly rare. We report a case of a 58-year-old woman presenting with fever, left flank pain, uncontrolled diabetes mellitus, and acute kidney injury. Initial non-contrast CT KUB showed left EPN with a large perinephric air-containing collection and loss of fat planes with the adjacent descending colon, raising suspicion of a reno-colic fi…

HPVoice: a single-blind three-arm RCT on social media communication strategies among adolescents in Tuscany, Italy.

INTRODUCTION: Cervical cancer is the first cancer potentially eliminable through widespread HPV vaccination. In Italy, despite free access, vaccine coverage among adolescents remains low. Psychological factors such as information avoidance (IA), the tendency to ignore threatening information, can influence vaccine decisions and contribute to vaccine hesitancy (VH). While social media offers new avenues for health communication, their effectiveness in reducing VH is uncertain. This study investigates the impact of Instagram-based communication strategies on adolescents' HPV knowledge and VH. M…

Communication Barriers and Health Literacy Gaps Undermine Equitable Healthcare for Deaf Sign Language Users: A Qualitative Study.

Introduction/ObjectiveDeaf sign language users face persistent barriers to equitable healthcare, yet evidence from non-Western and lower-income contexts remains limited. This study explored the lived experiences of Deaf undergraduate students in Thailand, examining how communication barriers, health literacy gaps, and system design intersect to shape their access to equitable care.MethodsWe conducted a qualitative study using semi-structured, in-depth interviews with ten Deaf undergraduate students (aged 18-22 years). Participants were recruited through purposive sampling and interviews were c…

Transferring Therapeutic Communication From Simulation to First Clinical Placement: A Qualitative Description of Undergraduate Nursing Students' Experiences.

Simulation-based learning is widely used to prepare nursing students for therapeutic communication, but transfer is often treated as if students acquire decontextualized skills in the laboratory and then apply them in clinical practice. This qualitative descriptive study explored how undergraduate nursing students experienced the transition from communicating with simulated patients to communicating with real patients during early clinical practice. Fifteen third-year Bachelor of Science in Nursing students in the United Arab Emirates who had completed the required Adult Health Nursing I simul…

Scoping Review of Communication Assessment Tools for Family Caregivers: Current Status, Clinical Translation Gaps, and Future Directions.

PURPOSE: Family caregivers (FCs) serve as essential intermediaries in illness-related communication; however, the instruments used to assess FC communication vary widely in terms of conceptual scope and methodological quality. This scoping review aimed to systematically identify the available instruments for assessing FC communication, map their conceptual domains and key psychometric characteristics, and delineate research gaps and future directions. METHODS: This review was guided by the Arksey and O'Malley methodological framework and is reported in accordance with the Preferred Reporting …

Parent-Clinician Communication and End-of-Life Preparation in Pediatric Oncology: An Explanatory Sequential Mixed-Methods Study.

PURPOSE: Parental preparedness for their child's end of life (EOL) may lessen perceived suffering and prolonged grief. Although clear communication may support parental preparedness, the specific communication components that influence this process remain poorly understood. This study examined how communication influences parental EOL preparation. METHODS: We employed an explanatory sequential mixed-methods design. We analyzed cross-sectional survey data from recently bereaved parents (6-24 months post-loss) using multiple logistic regression. Informed by quantitative findings, we conducted s…

Воздействие средств АИ, основанных на крупных языковых моделях, на физиологические и пациентские связи: систематический обзор и мета-анализ.

Недавний прогресс в крупных языковых моделях (МЖЛ), таких, как GPT-3/4 :: стимулировали развитие болтовн искусственного интеллекта (AI) и консультативных инструментов в области медицины. Эти системы предназначены для оказания помощи или расширения коммуникации между врачом и пациентом, что может способствовать улучшению сочувствия, ясности и реагирования. Однако их фактическое воздействие на результаты коммуникационной деятельности остается неопределенным.2020-2025) оценка того, каким образом принимаемые на базе ЛЛД меры влияют на общение между врачом и пациентом, включая сочувствие, ясность,

Совпадение в аннотации оригинала
BackgroundRecent advances in large language models (LLMs) such as GPT-3/4 have spurred the development of artificial intelligence (AI) chatbots and advisory tools in medicine. These systems are posited to assist or augment physician-patient communication, potentially improving empathy, clarity, and responsiveness. However, their actual impact on communicatio…

VARNet-6G with FIERO model for anomaly detection and enhancing network stability in future-ready communication systems.

The world is moving toward communication networks of 6G, so security will become a very essential aspect for the integrity and reliability of the system. Advanced anomaly detection and dropout rate estimation techniques are required due to the exponential rise in network traffic, diversity in applications, and interconnectivity of devices. Most of the anomaly detection models until now are encumbered with the issues of scalability, being adaptable to new types of attacks, and the capability of processing large, dynamic network data efficiently. In order to address these challenges, this paper …

Intraoperative Verbal Communication in Pediatric Single-Incision Laparoscopic Percutaneous Extraperitoneal Closure: A Comprehensive Analysis and Educational Implications.

INTRODUCTION: In pediatric surgery, declining case volumes and restrictions on working hours have intensified the need for efficient training strategies. The operating room remains a central educational environment, yet the nature of intraoperative teaching is unclear. We examined the educational role of intraoperative verbal communication and identified opportunities for improvement. METHODS: We retrospectively analyzed data of unilateral single-incision laparoscopic percutaneous extraperitoneal closure procedures performed between December 2024 and June 2025 with complete audio and video re…

Efficient Penetration of Terbinafine into Brain Abscesses in a Lung Transplant Recipient with Scedosporiosis: A Short Communication.

BACKGROUND: Scedosporium spp. typically infect the lungs and can disseminate to various tissues, including the central nervous system (CNS). Voriconazole and terbinafine are both used to treat scedosporiosis. While voriconazole has been reported to have good CNS permeability, the permeability of terbinafine in humans remains unclear. METHODS: The authors describe a case of Scedosporium apiospermum infection with brain abscesses in a lung transplant recipient treated with voriconazole and terbinafine. Drug concentrations were measured in the biopsied brain abscess, the surrounding normal cereb

Communication-based interventions to increase COVID-19 vaccine willingness and uptake: a systematic review with meta-analysis.

OBJECTIVE: This systematic review investigates the effectiveness of different communication strategies to increase COVID-19 vaccine uptake and willingness. DESIGN: Systematic review and meta-analysis of randomised controlled trials (RCTs), following recommendations from the Cochrane Handbook and reporting according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guideline. DATA SOURCES: We searched the following databases until 27 July 2022: Cochrane COVID-19 Study Register, PsycINFO, CINAHL, Web of Science Core Collection and WHO COVID-19 Global literature. ELIGIB…

The Moderating Role of Nonviolent Communication in the Relationship Between PTSD and Depressive Symptoms: A Longitudinal Investigation.

Background: The demoralization model of depression suggests that PTSD could lead to depressive symptoms. However, not all people with PTSD have co-occurring depressive symptoms. Objective: To examine the moderating role of nonviolent communication (NVC) behaviors in the relationship between PTSD and depressive symptoms. Methods: Longitudinal data were obtained from a sample of young adults (N = 146) online. They completed validated screening measures of PTSD symptoms, depressive symptoms, and NVC behaviors at baseline (T1), and reported their depressive symptoms again after three months (T2). …

Prevention of Early Childhood Caries from the First Level of Care: An Interdisciplinary Approach and Motivational Communication.

Early Childhood Caries (ECC) is considered one of the most prevalent chronic diseases globally, particularly affecting children in socially vulnerable situations. Its significance goes beyond oral health, undermining overall development and quality of life and placing a considerable economic burden on health systems. Given the inadequacy of conventional curative approaches, this manuscript proposes a preventive model based on primary care, structured around an interdisciplinary approach and family-based communication strategies. It analyzes, based on scientific evidence, the fundamental pillar…

Efficacy of communication interventions for promoting blood donation in low- and middle-income countries: A systematic review.

BACKGROUND AND OBJECTIVES: In low- and middle-income countries (LMICs), information on the efficacy of communication interventions promoting blood donation is very scarce. The present review aimed to identify specific communication interventions and their efficacy for increasing blood donation in LMICs. MATERIALS AND METHODS: The databases searched were PubMed, Scopus, PsycINFO, Web of Science, CINAHL, ProQuest, AJOL and CAB Abstracts. Grey literature sources included the websites of African Society of Blood Transfusion, International Society of Blood Transfusion and World Health Organization…

Communication preferences during the recovery phase of a hurricane disaster: Rural residents prefer face-to-face interaction.

OBJECTIVE: The recovery phase of the emergency management cycle is understudied. This research aimed to understand the communication preferences of rural residents with low literacy during the recovery phase of a hurricane and flooding disaster. METHODS: During October and November 2019, three focus groups (n = 32) were conducted with members of church congregations in three small townships in eastern North Carolina. Audio recordings were transcribed and coded for communication preferences and themes. RESULTS: Participants were primarily non-White (62 percent), over age 55 (78 percent), and …

Implementation and Evaluation of a Therapeutic Communication Educational Program for Nurses: Protocol for a Mixed Methods Study.

BACKGROUND: Admission to a hospital can be a very stressful and anxiety-provoking experience, as patients face many unknowns that can compromise their physical and psychological well-being. Patient-centered care necessitates that health care organizations and professionals actively comprehend patients' experiences and values, for which effective training in communication skills is essential. OBJECTIVE: This study will contribute to this field of research by evaluating a blended therapeutic communication training program. METHODS: The training consists of online e-learning that provides insig…