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Prevalence and distribution of human herpesvirus 6 variants A and B in adult human brain.

The presence of human herpesvirus 6 (HHV-6) in brain tissues of 40 consecutive post-mortem cases was examined. For each case, autopsy samples were collected from the cerebellum, frontal, temporal, parietal and occipital lobes of both sides of the brain. HHV-6 DNA was detected by nested polymerase chain reaction and characterised into variants A and B. Overall, 97/400 (24.3%) samples were positive for HHV-6 DNA with 16 being variant A and 81 being variant B, but none of the samples harboured both variants. When analysed by patient, 34/40 (85%) had HHV-6 DNA detected in the brain. The viral DNA

Children and adolescents with velocardiofacial syndrome: a volumetric MRI study.

OBJECTIVE: Velocardiofacial syndrome is a common genetic condition often accompanied by mild cognitive impairment. Children and adolescents … f regional morphological variation among the children with velocardiofacial syndrome. Specifically, frontal lobe tissue tended to be enlarged relative to the overall reduction in brain volume. Normal symmetry of parietal lobe tissue observed in the comparison group was not evident in the velocardiofacial syndrome group. This loss of symmetry was attributable t …

[Stroke-like course of brain tumors].

An analysis of 106 verified cases of brain tumours has been carried out. In one group of patients (51), a clinical picture of acute impairments of the blood circulation inside, in the vicinity and at the periphery of tumour is described. Specific features of the differential diagnosis of tumor and hemorrhagic stroke are presented. Some principles of the treatment of these patients are also offered. The other group (55 cases) has been studied to specify the differential diagnosis between brain tumour and ischemic stroke. The similarities and differences of the clinical picture in the tumour pat

Прогрессивный церебральный атрофий и когнитивный спад без церебрального излечения от нейромелитного расстройства Оптика Спектрума: доклад по делу.

Неврологические дефициты в расстройстве спектра нейромиелита (NMOSD) обычно считаются результатом острых рецидивов, в отличие от множественных склерозов (MS), которые часто прогрессируют без рецидивов из-за нейродегенерации. Однако мы представляем случай 41-летнего пациента мужского пола, который демонстрировал прогрессирующую двустороннюю лобную долю атрофии в течение девяти лет, хотя острые рецидивы ограничивались мышцами позвоночника и спинного мозга. Нейропсихологические тесты указывают на когнитивный спад. Этот случай свидетельствует о постепенном церебральном атрофии и когнитивном упадке

Совпадение в аннотации оригинала
Neurological deficits in neuromyelitis optica spectrum disorder (NMOSD) are conventionally thought to result from acute relapses, unlike multiple sclerosis (MS), which frequently progresses without relapse due to neurodegeneration. However, we present the case of a 41-year-old male patient who showed progressive bilateral frontal lobe atrophy over nine years…

Detection of Small Brain Metastases by 18 F-Thretide PET/CT in Clear Cell Renal Cell Carcinoma.

A 46-year-old woman with a history of radical nephrectomy for clear cell renal cell carcinoma underwent 18 F-FDG and 18 F-Thretid (also known as Al 18 F-PSMA-BCH) PET/CT. Although the 18 F-FDG PET/CT failed to detect any brain metastases, the 18 F-Thretide PET/CT revealed 2 small metastases: one measuring 1.0 × 0.7 cm in the right cerebellum and the other measuring 0.4 cm in the right frontal lobe. These metastatic lesions were subsequently confirmed by brain MRI.

Pediatric gliosarcoma, a rare central nervous system tumor in children: Case report and literature review.

Gliosarcoma is a rare and highly malignant central nervous system tumor that accounts for 1%-8% of glioblastomas; it usually occurs in middle-aged and older adults between 40 and 60 years of age and is rare in children. We report an 11-year-old boy with right frontal lobe gliosarcoma who underwent aggressive gross total resection and postoperative radiotherapy, experienced recurrence and subsequently underwent a second operation. To better understand the disease and explore treatment options, we briefly report this case and review the relevant literature.

Giant arachnoid cyst in adult presented with secondary epileptiform activity.

BACKGROUND: Current studies contain controversies regarding indications and preferable surgical techniques for arachnoid cysts. CASE DESCRIPTION: In this paper we present case report of giant arachnoid cyst of right frontal lobe in young left-handed adult with headache, MRI sings of brain compression and epileptiform activity on EEG, treated by microsurgical cystostomy. CONCLUSION: We add a case of young adult with tension headaches and possible sub-clinical seizures due to arachnoid cyst, whose symptoms disappeared after surgical management of the cyst, including normalization of EEG.

A Case of Fronto-Temporal Dementia (FTD) Masquerading as Mood Disorder.

A 56-year old Chinese female was referred to an academic medical center with atypical, treatment-resistant depression that continued for approximately 3 years after her sister's death. Comprehensive evaluation including neurocognitive testing, EEG, spinal tap, HIV testing and brain MRI revealed behavioral variant of fronto-temporal dementia (bvFTD) with significant frontal and temporal lobe atrophy.This patient's unusual clinical presentation emphasizes the overlap between depression and bvFTD, and underlines the importance of prompt, accurate diagnosis to minimize often-ineffective pharmacolo

Reversible hypertensive encephalomyelopathy - the spinal variant of the posterior reversible encephalopathy syndrome.

Posterior reversible encephalopathy syndrome (PRES) is characterised clinically by encephalopathy, headache, visual disturbance and/or focal neurological symptoms. Bilateral cerebral oedema on T2 MRI sequences within the posterior cerebral white matter is the radiological hallmark, although involvement of the frontal lobe, basal ganglia and brainstem can occur. PRES with spinal cord involvement has been rarely reported and is under-recognised due to lack of myelopathic features in nearly half of the reported cases. We report a patient with PRES with spinal cord involvement and review the liter…

Brain metastasis from invasive thymoma mimicking intracerebral hemorrhage: case report.

A 55-year-old man with an 8-year history of invasive thymoma presented with sudden onset of left hemiparesis. Computed tomography (CT) and magnetic resonance (MR) imaging showed a right frontal lobe intracerebral hemorrhage and the possibility of brain metastasis could not be rejected. The patient underwent removal of the hematoma. Histological examination showed brain metastasis from invasive thymoma. To the best of our knowledge, this is the first reported case of hemorrhagic brain metastasis from invasive thymoma (non-cancerous) mimicking intracerebral hemorrhage.

Pseudotumoral form of cerebral Schistosomiasis Mansoni.

The authors report a case of 36-year-old woman presented with epileptic seizures and headaches. Magnetic resonance imaging (MRI) revealed an enhancing lesion with surrounding edema and mild mass effect in the left frontal lobe. Stereotactic brain biopsy demonstrated intraparenchymal granulomas surrounding S. mansoni eggs. Praziquantel was started (60mg/kg of body weight, in a single dose), followed by Prednisone (80mg/day) for seven days to treat the cerebral edema. The patient's symptoms resolved following medical treatment and the follow-up MRI yielded normal findings.

Magnetic resonance imaging of intact globe superior subluxation into the intracranium.

A 67-year-old man with right-sided blunt ocular trauma is reported here. Despite having received primary medical care, the patient complained of severe headache for 14 days. Initial computed tomography (CT) indicated hematoma in the right frontal lobe. However, magnetic resonance imaging (MRI) indicated that the right globe along with its optic nerve had been intactly dislocated into the intracranium and differentiated from hematoma. In this case, the significance of MRI, in blunt ocular trauma work-up, and also regaining successful ocular function are highlighted.

Parietal lobe abnormalities detected with MR in patients with infantile autism.

OBJECTIVE: Infantile autism is a neurologic disorder that severely disrupts the development of many higher cognitive functions. The most con … body (two patients). Abnormalities were bilateral. The mesial, lateral, and orbital regions of the frontal lobes; temporal lobes; limbic structures; basal ganglia; diencephalon; and brainstem were normal in all autistic patients. No abnormalities were found in the 12 normal control subjects. The control subjects with neurologic abnormalities had various abnor …

[Mental disorders and their relation to brain lesion location: diagnostic problems].

Knowledge of symptoms of appropriate brain areas lesion helps to differ psychiatric and neurological disorders. The objective of our work was to find out the situation in scientific research about mental disorder relation to brain lesion location and to except the location of lesions, which are most complicated in differential diagnosis. We discussed the relation of most important mental disorders to brain lesion location. The study of discrete organic cerebral lesions resulting in clearly definable psychiatric disorders may provide an understanding of the underlying pathophysiological basis o

Application and validation of three-dimensional data sets from a phase contrast MR angiography for preoperative computer simulation of brain tumors.

We applied a three-dimensional (3D) phase contrast magnetic resonance angiography as the source for generating integrated 3D images for surgical planning of brain tumors. In the 3D model, we defined the Cingulomarginal sulcus and subsequently the central sulcus in the interhemispheric plane. This method solved the misregistration problem caused by the combination of multi-sequence data sets and can be feasible for surgical planning.

Effects of traumatic brain injury on the cholinergic system in the rat.

Rats subjected to a mild to moderate fluid percussion injury exhibit memory deficits that are similar to rats that have received lesions of the septohippocampal system. Because the cholinergic system plays a major role in septohippocampal function, we studied the kinetics of the synthetic enzyme for acetylcholine, choline acetyltransferase (ChAT), at 1 h, 24 h, or 5 days after a fluid percussion injury. Decreases in ChAT activity were found in the dorsal hippocampus (25%), frontal (32%), and temporal (23%) cortices 1 h after injury. In the parietal cortex, a greater than 50% increase in ChAT a

Acute effect of Ethanol and Taurine on frontal cortex absolute beta power before and after exercise.

Ethanol (ET) is a substance that modulates the Central Nervous System (CNS). Frequently, ET intake occurs combined with energy drinks, which … lography (EEG) tests were conducted in order to analyze changes in absolute beta power (ABP) in the frontal lobe in 3 moments: baseline (before ingestion), peak (before exercise) and post-exercise. In the PL treatment, the frontal areas showed decrease in ABP after exercise. However, in the ET+TA treatment, ABP values were greater after exercise, except for Fp …

Arterial spin-labeling MR imaging measurements of timing parameters in patients with a carotid artery occlusion.

BACKGROUND AND PURPOSE: Arterial spin-labeling (ASL) with image acquisition at multiple delay times can be exploited in perfusion MR imaging … c status. In patients with leptomeningeal collaterals, the most impaired territory was found in the frontal lobe.

Frontal cortical volume deficits as enduring evidence of childhood abuse in community adults with AUD and HIV infection comorbidity.

BACKGROUND: Childhood abuse is an underappreciated source of stress, associated with adverse mental and physical health consequences. Childh … ion of a laboratory control group. RESULTS: History of childhood abuse was associated with smaller frontal lobe volumes regardless of diagnosis. For frontal subregional volumes, history of childhood abuse was selectively associated with smaller orbitofrontal and supplementary motor volumes. In participants with a child abuse history, poorer verbal/visual memo …