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Assessment of acute renal failure patients treated in our nephrology clinic between 1996 and 2002.

Acute renal failure (ARF) is a cause of high morbidity and mortality associated with long hospital stay, and expensive treatment. The initia … are of the opinion that early referral of patients to a nephrologist and following treatment in the nephrology clinic may positively affect the outcome.

Canadian Society of Nephrology Commentary on the Evolving Kidney Disease Improving Global Outcomes Adult Glomerulonephritis Guidelines.

Purpose of reviewThe purpose of this commentary is to address the challenges of implementing the evolving Kidney Disease Improving Global Ou … l as the 2025 updated guideline for immunoglobulin A (IgA) nephropathy.MethodsA Canadian Society of Nephrology (CSN) working group with expertise in GN was formed, representing nephrologists, pathologists, pharmacists, and patient partners with geographic representation from across Canada. Recommendations and practice points were reviewed by member surveys, …

Transforming chronic kidney disease care with telemedicine: expert consensus recommendations from the Italian Society of Nephrology.

Chronic kidney disease (CKD) affects 10-13% of adults worldwide and imposes a substantial burden on healthcare systems. Telemedicine has emerged as a key tool to support nephrology care by improving access, continuity, and patient engagement across CKD, dialysis, and transplant pathways. To guide its integration into routine practice, the Italian Society of Nephrology (SIN) convened a multidisciplinary working group to develop expert consensus recommendations on the use of telemedicine in nephrology. The consensus process included moderated meetings, topic-specific task forces, iterative draft…

Artificial intelligence virtual cells as a new paradigm in nephrology: from multiomics integration to clinical translation.

Kidney diseases remain heterogeneous and mechanistically complex, and current experimental models only partially capture patient-specific dy … g with interoperable data standards and governance, AIVCs offer an actionable roadmap for precision nephrology.

Повторная оценка биопсии почек в связи с диабетической болезнью почек: гистопатология, курс клинической медицины и будущее точной нефрологии.

Фон: диабетическое заболевание почек (DKD) one :: основные причины хронических заболеваний и почечной недостаточности во всем мире. Хотя большинство пациентов, страдающих диабетом, диагностируются клинически на основе албуминурии, предполагаемого снижения уровня глумерной фильтрации и диабетической ретинопатии, одни только клинические параметры не могут надежно отличать биопсию, подтвержденную диабетической нефропатией (ННН), от недиабетической болезни почек (НДКД) или смешанных повреждений. Таким образом, биопсия почек для больных диабетом по-прежнему носит избирательный, а не рутинный характ

Совпадение в аннотации оригинала
Background: Diabetic kidney disease (DKD) is one of the leading causes of chronic kidney disease and kidney failure worldwide. Although most … rather than routine, but its diagnostic and prognostic value is increasingly relevant in precision nephrology. Methods: This narrative review summarizes clinicopathological evidence on kidney biopsy in patients with diabetes, with particular emphasis on the Renal Pathology Society classification of DN, the prognostic significance of glomerular, tubulointers …

Vaccination gaps in incident hemodialysis patients: An opportunity for preventive nephrology, a prospective, cross-sectional study.

BACKGROUND: Patients initiating hemodialysis face heightened infection risks due to immunodeficiency and frequent healthcare exposure. Vaccinations against hepatitis B virus (HBV), Streptococcus pneumoniae, and influenza are recommended but often underutilized, particularly in resource-constrained settings. AIM: To evaluate the baseline vaccination status and associated factors of patients starting hemodialysis in a tertiary nephrology center in North India, with the goal of identifying any overlooked opportunities for preventive care. METHODS: A prospective cross-sectional study was conduct…

Pancreas Transplant Training in U.S. Transplant Nephrology Fellowships: National Survey of Current Barriers and Potential Solutions.

Limited training opportunities for transplant nephrologists have been identified as a potential contributing factor for declining pancreas transplant volumes. However, data describing pancreas transplant training within transplant nephrology fellowships are scarce. We conducted a survey of 66 accredited U.S. transplant nephrology fellowship programs between December 2024 and May 2025 to assess perceived barriers and strategies to enhance pancreas transplant training. A total of 48 (72%) responses were received. A significant number of programs (n = 21; 44%) reported that they did not graduate …

Vibe Coding in nephrology education: clinician-led, AI-assisted development of open-source interactive learning tools.

Medical education increasingly incorporates digital technologies; however, many tools remain passive and text-based. Vibe Coding is a clinician-led design framework that embeds expert reasoning and the cognitive 'feel' of clinical decision-making into interactive educational tools. This study demonstrates its application in nephrology training through the rapid development of open-source, AI-assisted, web-based applications. We conducted a proof-of-concept development study using a structured, physician-led, AI-assisted process combining (1) deconstruction of clinical algorithms, (2) natural-l…

A practical guide for nephrologist peer reviewers: evaluating artificial intelligence and machine learning research in nephrology.

Artificial intelligence (AI) and machine learning (ML) are transforming nephrology by enhancing diagnosis, risk prediction, and treatment optimization for conditions such as acute kidney injury (AKI) and chronic kidney disease (CKD). AI-driven models utilize diverse datasets-including electronic health records, imaging, and biomarkers-to improve clinical decision-making. Applications such as convolutional neural networks for kidney biopsy interpretation, and predictive modeling for renal replacement therapies underscore AI's potential. Nonetheless, challenges including data quality, limited ex…

Perspectives of Chinese nephrology nurses on discussing sexual dysfunction with patients receiving haemodialysis: A qualitative study.

BACKGROUND: The study underscores the crucial yet often neglected issue of sexual dysfunction in haemodialysis patients. Despite nephrology nurses'close relationships with patients, there is a significant communication gap on this topic. In China, limited research highlights the need for further study. OBJECTIVE: To describe the perspectives of Chinese nephrology nurses on discussing sexual dysfunction with patients receiving haemodialysis. DESIGN: A qualitative descriptive study. PARTICIPANTS: Ten Chinese nephrology nurses from a tertiary public hospital in Guizhou province, China. APPROA…

Blood Pressure Outcomes in NICU-Admitted Infants with Neonatal Hypertension: A Pediatric Nephrology Research Consortium Study.

OBJECTIVE: To describe the blood pressure outcomes of infants admitted to the neonatal intensive care unit (NICU) with idiopathic (nonsecondary) hypertension (HTN) who were discharged on antihypertensive therapy. STUDY DESIGN: Retrospective, multicenter study of 14 centers within the Pediatric Nephrology Research Consortium. We included all infants with a diagnosis of idiopathic HTN discharged from the NICU on antihypertensive treatment. The primary outcome was time to discontinuation of antihypertensive therapy, grouped into (≤6 months, >6 months to 1 year, and >1 year). Comparisons between …

Improvement in Kidney Function after Discontinuation of Fenofibrate in Outpatient Nephrology Consultation for Chronic Kidney Disease.

BACKGROUND: It has been noted in observational and interventional studies that individuals exposed to fenofibrate can exhibit a rise in serum creatinine (sCr) concentration. However, it is not known to what extent this phenomenon impacts kidney function in patients who are referred to a nephrology clinic for consultation for chronic kidney disease (CKD). METHODS: We conducted a prospective observational study of patients referred to our nephrology clinic for a new evaluation of a rise in sCr or worsening CKD and who were on fenofibrate therapy. We examined the effect of discontinuation of fen…

Using interpretability approaches to update "black-box" clinical prediction models: an external validation study in nephrology.

Despite advances in machine learning-based clinical prediction models, only few of such models are actually deployed in clinical contexts. Among other reasons, this is due to a lack of validation studies. In this paper, we present and discuss the validation results of a machine learning model for the prediction of acute kidney injury in cardiac surgery patients initially developed on the MIMIC-III dataset when applied to an external cohort of an American research hospital. To help account for the performance differences observed, we utilized interpretability methods based on feature importance

Kidney transplantation in children with decreased left ventricular systolic function: a Midwest Pediatric Nephrology Consortium study.

BACKGROUND: Left ventricular (LV) systolic dysfunction is a relatively uncommon but serious complication of pediatric chronic kidney disease, and may be related to uremia and uncontrolled hypertension. There is limited information on the strategy for managing these children. In some cases, combined heart-kidney transplant may be considered or kidney transplant delayed until cardiac function improves. It is unknown whether these patients are at increased risk for poor outcomes after kidney transplantation. METHODS: We conducted a retrospective, multicenter study on the outcomes of children wit

Renal histopathology in fatal cases of diarrhoea-associated haemolytic uraemic syndrome. British Association for Paediatric Nephrology.

Autopsy material was examined from British children dying early in the course of haemolytic uraemic syndrome (HUS). These presented after 1983, the period in which verocytotoxin-producing Escherichia coli (VTEC) infection was confirmed as the leading cause of diarrhoea-associated (D+HUS) in the United Kingdom. Of 18 cases referred for this study, 3 were found on review to have no history of a diarrhoeal prodrome (D-HUS). In the D+ patients, the median duration from onset of diarrhoea to death was 8 days (range 4-42 days). VTEC infection was confirmed in 6 cases. All had neutrophilia at present

Acute kidney injury at a tertiary nephrology referral center: predictors of renal recovery and in-hospital mortality.

BACKGROUND: Acute kidney injury (AKI) is a global health problem associated with substantial morbidity, mortality, and healthcare costs. Despite advances in prevention and management, in-hospital mortality remains high, particularly among critically ill patients. OBJECTIVES: To determine incidence, risk factors of AKI among patients admitted to Mansoura Nephrology and Dialysis Unit (MNDU), a tertiary nephrology referral center in Dakahlia governorate, Egypt, over one year, and to identify predictors of renal recovery at discharge and in-hospital mortality. METHODS: This prospective observati…

Letter to the Editor: Artificial intelligence in nephrology point-of-care ultrasonography - opportunities, limitations, and future directions.

We read with interest the retrospective cohort study by Silipigni et al entitled "Role of point-of-care ultrasonography in kidney disease management: A single solution for multiple challenges". Artificial intelligence (AI) is rapidly reshaping the way clinicians learn, perform, and interpret point-of-care ultrasonography (POCUS). In nephrology, AI-assisted image acquisition, automated measurements, and emerging decision-support tools offer opportunities to improve efficiency and expand access to POCUS training. At the same time, important limitations remain, particularly when ultrasound findin…

Therapeutic Apheresis Registry of the Spanish Society of Nephrology. Analysis of activity over the last five years.

INTRODUCTION: Therapeutic apheresis (TA) is an extracorporeal technique used to treat various renal and non-renal pathologies, for which the ASFA guidelines provide recommendations. In Spain, nephrology services have progressively adopted various forms of TA, and since 2018, the Spanish Society of Nephrology (S.E.N.) has maintained a national TA registry to monitor its use. OBJECTIVE: To describe the activity of nephrology services participating in the TA registry of the S.E.N (AFT-S.E.N.) between 2019 and 2023. MATERIAL AND METHODS: A descriptive observational study was conducted that inclu…

Kidney-Lung Crosstalk in Acute Nephrologic Involvement: Mechanisms, Complement Activation, and Implications for Multiorgan Dysfunction.

Acute kidney injury (AKI) is a systemic syndrome capable of inducing remote organ dysfunction. Kidney-lung crosstalk is a form of interorgan communication in acute nephrology, with the heart acting as a pivotal intermediary. Emerging evidence supports the involvement of a gut-lung-kidney axis. Complement activation in these multiorgan crosstalk has emerged as a central amplifier of multiorgan damage. We reviewed the literature on kidney-lung interactions and complement activation in AKI through a bibliographic search of PubMed, Scopus, and Web of Science. Most available data derive from experi…

Outcomes from the International Society of Nephrology forum on complement therapeutics in C3 glomerulopathy and IgA nephropathy.

C3 glomerulopathy (C3G) and primary immune-complex membranoproliferative glomerulonephritis (IC-MPGN) are both prototypical complement disor … they should be used in the real world. We report the findings of the 2025 International Society of Nephrology Forum on Complement Therapeutics in C3G and IgAN, where a global panel of experts considered the current state of knowledge, identified areas of uncertainty, and proposed optimal solutions. Areas of uncertainty and areas for future research included …