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A Generational Approach to Neurology Education: Engaging Generation Z Learners.

Neurophobia remains a persistent barrier in neurology education because learners often struggle to connect neuroanatomy, localization, examination findings, and clinical reasoning. At the same time, Generation Z learners now comprise much of undergraduate and graduate medical education and have trained in an environment shaped by ubiquitous mobile technology, short-form media, rapid information retrieval, and heightened attention to feedback, well-being, and belonging. This review synthesizes literature on neurophobia, Gen Z learner preferences, cognitive load, active learning, simulation, mul…

JAK2V617F Mutation in Ischemic Stroke: Bridging Hematology and Stroke Neurology.

Recent evidence suggests the JAK2V617F mutation may confer an elevated risk of ischemic stroke, likely mediated by systemic inflammation, ab … mbosis, its contribution to cerebrovascular risk, and the emerging relevance of JAK2V617F in stroke neurology. Current knowledge underscores the value of JAK2V617F testing in stroke patients for early detection of myeloproliferative neoplasms or pre-myeloproliferative neoplasm states and personalized secondary stroke prevention. Further studies are needed t …

Bridging nutrition and neurology: malnutrition's role in perioperative neurocognitive disorders.

This literature review examines the relationship between malnutrition and perioperative neurocognitive disorders (PND), which encompass cognitive impairments occurring throughout the perioperative period, including pre-existing cognitive impairments, postoperative delirium, delayed neurocognitive recovery, and postoperative cognitive dysfunction. Malnutrition is associated with an increased incidence of PND, affecting patient recovery and quality of life. Studies suggest that preoperative malnutrition may heighten the risk of PND, and that preoperative nutritional diagnosis and perioperative n

Advanced neuroimaging in precision neurology: Tools, trends, and translational impact.

Advances in neuroimaging are revolutionizing the landscape of precision neurology by enabling high-resolution, multimodal visualization of brain structure, function, and pathology. As traditional, symptom-based frameworks fall short in capturing the biological complexity of neurodegenerative diseases, imaging modalities such as structural MRI, diffusion tensor imaging, functional MRI, PET, and hybrid PET/MRI have emerged as essential tools for early diagnosis, patient stratification, and therapeutic monitoring. These technologies not only reveal hallmark features like hippocampal atrophy and d…

Inpatient Implementation of Portable Ocular Fundus Photography Among Neurology Residents.

Background: Nonmydriatic ocular fundus photography has been studied with demonstrated benefit in the evaluation of emergency department neurological complaints, particularly in triaging headache and focal neurological deficits. Likewise, portable fundus camera usage may be practical for inpatients with neurological complaints, although feasibility has not been studied in a neurology teaching service. Purpose: The objective of this study is to determine if a portable, nonmydriatic fundus camera could be integrated into routine clinical care by neurology inpatient housestaff at a tertiary medica…

Understanding the genetics and neurology: an overview of adult neurogenetics.

Neurogenetics investigates the genetic basis of neurological disorders. It encompasses conditions ranging from neurodegenerative diseases with predominantly polygenic risk genes, such as Alzheimer's and Parkinson's, to monogenic diseases and repeated expansion disorders within movement and neuromuscular disorders, such as Friedreich ataxia and muscular dystrophies. Significant advances in recent years that have revolutionized our understanding of disease mechanisms and paved the way for personalized medicine approaches are due to the field of neurogenetics, with its intricate relationship both

'Father of neonatal neurology': the life of Joseph J. Volpe.

Dr. Joseph J. Volpe, a prominent figure in neonatal neurology, has made many important contributions to the understanding and treatment of brain injuries in newborns, particularly premature infants. Over his 60-year career, Volpe conducted pioneering research in the basic and clinical aspects of neonatal brain development and pathology. He played a key role in advancing neonatal care, improving outcomes for premature infants, and shaping the field of neonatal neurology. Volpe's early neurology career at Harvard Medical School and later work at Massachusetts General Hospital and Washington Univ…

Знания и отношение к эпилепсии неврологических амбулаторных служб в Тюркие.

Мы стремились оценить уровень знаний и отношения, связанных с эпилепсией, среди неврологических амбулаторных больных без диагноза эпилепсии. МАТЕРИАЛЫ И МЕТОДЫ: Шкала знаний о эпилепсии и отношения к ней была применена к 331 взрослому пациенту, который получил различные диагнозы в амбулаторной клинике неврологии. Результаты: В нем приняли участие 331 человек, в том числе 51,4% женщин и 48,6% мужчин. По мере повышения уровня образования наших участников значительно возрастает уровень знаний и менталитета (p <0,001). Знания и отношение тех, кто знал о человеке с эпилепсией, были значительно выше

Совпадение в аннотации оригинала
BACKGROUND/AIM: We aimed to evaluate the level of epilepsy-related knowledge and attitude among neurology outpatients without an epilepsy diagnosis. MATERIALS AND METHODS: The Epilepsy Knowledge and Attitude Scale was applied to 331 adult patients who were evaluated with various diagnoses in the neurology outpatient clinic. RESULTS: The participants compri…

Forensic Neurology and the Role of Neurologists in Forensic Evaluations.

Forensic psychiatrists may be asked to opine on neurological evidence or neurological diseases outside the scope of their expertise. This article discusses the value of involving experts trained in behavioral neurology in such cases. First, we describe the field of behavioral neurology and neuropsychiatry, the subspecialty available to both neurologists and psychiatrists focused on the behavioral, cognitive, and neuropsychiatric manifestations of neurological diseases. Next, we discuss the added value of behavioral neurologists in forensic cases, including assisting in the diagnostic evaluatio…

Integrated Care in Neurology: The Current Landscape and Future Directions.

The rising burden of neurological disorders poses significant challenges to healthcare systems worldwide. There has been an increasing momentum to apply integrated approaches to the management of several chronic illnesses in order to address systemic healthcare challenges and improve the quality of care for patients. The aim of this paper is to provide a narrative review of the current landscape of integrated care in neurology. We identified a growing body of research from countries around the world applying a variety of integrated care models to the treatment of common neurological conditions…

Eufemiusz J. Herman: A Pioneer and Leader in Polish Neurology.

Eufemiusz J. Herman was a pioneering figure in Polish neurology whose contributions spanned clinical practice, research, and education. Born in 1892, his career was marked by a deep understanding of neurological semiology, which he honed under the mentorship of Edward Flatau. Herman was a true scientist and physician, demonstrating his dedication to research even before graduating from medical school. His commitment to scientific inquiry persisted even during the harrowing conditions of the Warsaw Ghetto, where, amidst an epidemic of typhus, he documented and treated the neurological complicat…

Toward Quantitative Neurology: Sensors to Assess Motor Deficits in Dementia.

BACKGROUND: Alzheimer's disease (AD) is the most common neurodegenerative disorder which primarily involves memory and cognitive functions. It is increasingly recognized that motor involvement is also a common and significant aspect of AD, contributing to functional decline and profoundly impacting quality of life. Motor impairment, either at early or later stages of cognitive disorders, can be considered as a proxy measure of cognitive impairment, and technological devices can provide objective measures for both diagnosis and prognosis purposes. However, compared to other neurodegenerative di

Alzheimer Disease Cerebrospinal Fluid Biomarkers in a Tertiary Neurology Practice.

OBJECTIVE: To evaluate the performance of Alzheimer disease (AD) cerebrospinal fluid (CSF) biomarkers in a tertiary neurology clinic setting with high frequency of non-AD cases, including normal pressure hydrocephalus (NPH). METHODS: There were 534 patients who underwent AD CSF biomarkers (Roche Elecsys Aβ42, p-Tau181, total-Tau) from April 1, 2020, through April 23, 2021. A behavioral neurologist blinded to CSF results assigned a clinical diagnosis retrospectively on the basis of consensus criteria, and a neuroradiologist blinded to the diagnosis and CSF studies graded brain magnetic resonan…

Plasma Exchange in Pediatric Neurology Patients: A Single-Center Experience.

BACKGROUND: Therapeutic plasma exchange (TPE) is a procedure involving the filtration of a patient's plasma to eliminate pathogenic components or address deficiencies. This technique finds varied indications in the pediatric age group, particularly in neuroinflammatory diseases. OBJECTIVES: The objective of this study is to delve into our local experience with TPE, focusing on indications, outcomes, and complications among children with neurological diseases at King Abdulaziz University Hospital (KAUH) in Jeddah, Saudi Arabia. RESULTS: Conducted at the pediatric department of KAUH in Jeddah

Application of Functional Neurology Therapy in a Lactose-Intolerant Patient.

This case report examines the impact of a single session of functional neurology on a 35-year-old female patient diagnosed with lactose intolerance. The patient presented with severe gastrointestinal symptoms, including frequent diarrhea, bloating, and vomiting upon dairy consumption. The intervention aimed to reset dysfunctional neurological programs believed to contribute to her condition. The study utilized a standardized lactose intolerance breath test to measure the hydrogen and methane levels at various intervals before and after treatment. Post-treatment results showed symptomatic relie…

Fundoscopy in the smartphone age: current ophthalmoscopy methods in neurology.

The observation of the human retina in vivo began in 1851 after the invention of the first ophthalmoscope by the German physicist Hermann von Helmholtz. In the following decades, direct and indirect ophthalmoscopy, with the use of ophthalmoscopes and condensing lenses, respectively, became part of the clinical examination, especially in ophthalmology and neurology. Today, over 170 years later, many ophthalmoscopes and condensing lenses exist on the market. Nevertheless, ophthalmoscopy is still not widely adopted as part of the physical exam of general practitioners, and the teaching of ophthal…

Assessment of ChatGPT's performance on neurology written board examination questions.

BACKGROUND AND OBJECTIVES: ChatGPT has shown promise in healthcare. To assess the utility of this novel tool in healthcare education, we evaluated ChatGPT's performance in answering neurology board exam questions. METHODS: Neurology board-style examination questions were accessed from BoardVitals, a commercial neurology question bank. ChatGPT was provided a full question prompt and multiple answer choices. First attempts and additional attempts up to three tries were given to ChatGPT to select the correct answer. A total of 560 questions (14 blocks of 40 questions) were used, although any ima…

Child Neurology: Mucopolysaccharidosis IIID: Evidence From Ultrastructural and Genomic Study.

Mucopolysaccharidosis IIID (MPS IIID/Sanfilippo syndrome D, OMIM # 252940) is an autosomal recessive lysosomal storage disorder (LSD) and the rarest form of the mucopolysaccharidosis (MPS) III subtypes. It is caused by sequence variations in the gene encoding lysosomal enzyme N-acetyl glucosamine-6-sulphatase (GNS). Deficiency of GNS impairs catabolism of glycosaminoglycans causing accumulation of heparan sulphate within lysosomes of various tissues, which is visualized as membranous cytoplasmic bodies (MCBs) on electron microscopy. The recognition of this ultrastructural feature in a muscle b

The Neuropsychiatric Approach to the Assessment of Patients in Neurology.

Neuropsychiatry is a clinical neuroscience specialty focused on the evaluation and treatment of patients who present with symptoms at the intersection of neurology and psychiatry. Neuropsychiatrists assess and manage the cognitive, affective, behavioral, and perceptual manifestations of disorders of the central nervous system. Although fellowship training in behavioral neurology-neuropsychiatry exists in the United States and several other countries internationally, the need for neuropsychiatric expertise greatly outweighs the number of specialists in practice or training. This article serves …

Military traumatic brain injury: a challenge straddling neurology and psychiatry.

Military psychiatry, a new subcategory of psychiatry, has become an invaluable, intangible effect of the war. In this review, we begin by ex … itary TBI is both neuropathic and psychopathic, and is an emerging challenge at the intersection of neurology and psychiatry.