Результаты поиска

Clinical trials in pediatric uveitis.

Uveitis associated with juvenile rheumatoid arthritis is the most common form of ocular inflammation in children. Prevention of permanent visual damage by this silent disease requires heightened awareness from pediatric rheumatologists and ophthalmologists. Early prediction of severity and prognosis will aid in the identification of those patients requiring more aggressive management. Generally, reports using immunosuppressives in this population are small, uncontrolled, and retrospective. Large-scale collaborative studies have been proposed and are underway. Hopefully, collaborations between …

Pediatric Ophthalmology Scope of Practice.

PURPOSE: To determine practice patterns of pediatric ophthalmologists with respect to types of medical conditions cared for and age of patients treated due to limited data regarding pediatric ophthalmologists' scope of practice. METHODS: A survey was sent to 1408 international and United States members of the American Association for Pediatric Ophthalmology and Strabismus (AAPOS) membership through the group's internet listserv. Responses were collated and analyzed. RESULTS: Ninety members (6.4%) responded. 89% of respondents confine their practices to pediatric ophthalmology and adult strab…

[Results of full binocular correction versus conventional methods].

UNLABELLED: 163 patients suffering from different serious troubles were treated with binocular full correction (BFC) i.e. examination by Polatest and prismatic correction. Before, they all had seen other ophthalmologists. The former diagnose and therapy are listed and compared with those of the author. RESULTS: After a 2 2/3 years average follow-up period 68% of the patients were complaintless, 23% felt better. All patients reached at least binocular single vision, although initially 13% had no binocular vision and 1% complained about diplopia. 70% got ideal binocular vision (initially 0%). I…

Deep Learning Automated Detection of Reticular Pseudodrusen from Fundus Autofluorescence Images or Color Fundus Photographs in AREDS2.

PURPOSE: To develop deep learning models for detecting reticular pseudodrusen (RPD) using fundus autofluorescence (FAF) images or, alternati … deep learning model was trained to detect RPD from CFP (CFP model). Performance was compared with 4 ophthalmologists using a random subset from the full test set. MAIN OUTCOME MEASURES: Area under the receiver operating characteristic curve (AUC), κ value, accuracy, and F1 score. RESULTS: The FAF model had an AUC of 0.939 (95% confidence interval [CI], 0.927-0.9 …

An emergency corneal ulcer kit.

Bacterial corneal ulcer is a potentially blinding emergency which should ideally be treated by an ophthalmologist aided by slit lamp biomicroscopy, microbial stain and cultures, and then selected fortified topical antibiotics. We suggest an emergency corneal ulcer kit for the initial treatment of patients with suspected corneal ulcers who are unable to readily travel to an ophthalmologist.

Alezzandrini syndrome mimicking shingles - A rare case report with review of literature.

Alezzandrini syndrome (AS) is a rare entity characterized by segmental vitiligo on the face with ipsilateral poliosis, degenerative retiniti … eened for retinal degeneration and hearing defects. Patients with AS should be managed by a team of ophthalmologists, dermatologists, and otorhinologists.

Management of neurovascular emergencies with ophthalmic manifestations.

Patients with neurovascular disorders sometimes approach the ophthalmologists with mild ophthalmic clinical features such as conjunctival congestion, slowly progressive proptosis, lateral rectus palsies and at other times with ophthalmic emergencies like sudden increase in proptosis, ophthalmoplegia, diplopia, and ptosis before the onset of neurological manifestations which may be life-threatening if not detected in time. The aim of this article is to focus on ophthalmic manifestations of neurovascular emergencies and role of ophthalmologists in its management. In this communication, to make t…

Clinical findings provide criteria to evaluate priorities of ophthalmologic intervention in conscious multiple trauma patients.

INTRODUCTION: Multiple trauma patients frequently suffer eye injuries, especially those patients with head traumas. We evaluated the accuracy of physical findings to determine the priorities of emergency ophthalmologic intervention in these patients. PATIENTS AND METHODS: This study included all multiple trauma patients with ophthalmic trauma who had a GCS of 15 when they arrived at the emergency department during the period of March, 2008-March, 2009. First, we evaluated the patients according to the criteria of the study. Then, an ophthalmologist evaluated them. RESULT: From March 2008-Mar

Belantamab mafodotin, lenalidomide, и дексаметазон для пациентов среднего и слабого типа с недавно поставленным диагнозом миэлома.

Резюме фазы 1/2 В исследовании BelaRd (belantamab mafodotin [беламаф], lenalidomide и dexamethasone) была проведена оценка эффективности и безопасности беналафа в сочетании с линалидомидом и дексаметазоном у недееспособных и слабых пациентов, имеющих право на трансплантацию, с недавно поставленным диагнозом множественной миеломы (НДММ). Часть 1 (n = 36) установить рекомендованный бенамаф фазы 2 Доза (RP2D) 1.9 мг/кг каждый 8 недель (срочная последующая деятельность, 39.3 Месяцами). Частично 2, 30 пациенты были случайными 1::1 в группу А (n = 15), где дозирование беналафа осуществлялось на осно

Совпадение в аннотации оригинала
AbstractThe phase 1/2 BelaRd (belantamab mafodotin [belamaf], lenalidomide, and dexamethasone) study evaluated the efficacy and safety of be … 0% and 97.2%, respectively. Ocular toxicities were similar between assessments by hematologists and ophthalmologists, and no ophthalmologist withholding of a hematologist-led dosing occurred. Less than 1% of patients stopped driving/reading because of OAEs. Median time to belamaf reinfusion was 13 weeks. Overall, BelaRd is an effective regimen for transplant-ineli …

Ocular injuries and the most common acute conditions in ophthalmology.

Ocular traumas include a wide range of injuries from trivial conditions to extensive perforating injuries that can lead to visual function impairment of various ranges and even to the loss of the eye itself. In terms of first aid, not only an ophthalmologist but also a physician of any specialty can effectively intervene and minimize the consequences of these conditions. Open globe injuries represent prognostically the most severe conditions which have to be treated by an experienced ophthalmologist. Closed injuries are most commonly manifested as corneal erosions, foreign bodies on the surfac

[Retinopathy of prematurity screening and follow-up with Retcam120: expertise of a team of neonatologists concerning 145 patients].

OBJECTIVES: The high incidence of retinopathy in very premature infants requires strict evaluation and follow-up in neonatal intensive care. The strict organization required in each center, under the responsibility of ophthalmologists, is sometimes puzzling. Therefore, we tested the hypothesis that the introduction of the Retcam allows the neonatologist under the control of ophthalmologist to diagnose retinopathy of prematurity then preventing sequelae, by comparison of pictures interpretations between neonatologists and ophthalmologists. METHODS: The Retcam gives a 120 degrees picture of the…

Correlation between practice location as a surrogate for UV exposure and practice patterns to prevent corneal haze after photorefractive keratectomy (PRK).

BACKGROUND: PRK is a refractive surgery that reshapes the corneal surface by excimer laser photoablation to correct refractive errors. The effect of increased ultraviolet (UV) exposure on promoting post-PRK corneal haze has been reported in the literature; however, information is lacking regarding the effect of ambient UV exposure on physician practice patterns. The aim of this study was to evaluate the effect of ophthalmologists' practice location on their reported practice patterns to prevent post-PRK corneal haze. METHODS: A cross-sectional observational study was conducted through an onli…

Sensitivity and specificity of the diagnosis of periocular lesions by oculoplastic surgeons.

BACKGROUND: A few studies have assessed the sensitivity of ophthalmologists in diagnosing periocular lesions. However, no study has assessed their diagnostic specificity or the degree to which they overdiagnose various lesions. We performed a study to determine the sensitivity and specificity of oculoplastic surgeons' preoperative diagnoses of common and uncommon periocular lesions. METHODS: Using the patient records of four oculoplastic ophthalmologists, we reviewed all charts documenting periocular surgery in which lesions were excised and sent for biopsy. For each of 358 cases we recorded …

What to tell the patient with optic neuritis about multiple sclerosis.

If the ophthalmologist tells the patient with an initial isolated attack of optic neuritis that multiple sclerosis may develop, will he/she worry the patient needlessly or provide useful information that the patient is rightfully entitled to have? In this set of articles, the philosophies and individual circumstances that should influence the ophthalmologist in deciding what information to supply are discussed.

DiFFA: A Diffusion-Based Model for Synthetic Fundus Fluorescein Angiography to Enhance Detection of Diabetic Microvascular Complication.

PURPOSE: To develop diffusion-based fundus fluorescein angiography (DiFFA), a noninvasive method for generating high-quality FFA images from … ty index measure, and Fréchet inception distance metrics, (2) subjective authenticity evaluation by ophthalmologists, (3) diagnostic efficiency assessment, and (4) automated classification accuracy for diabetic retinopathy and diabetic kidney disease using VGG16 with and without synthetic FFA images. RESULTS: DiFFA achieved strong objective performance (mean abso …

Analysing the effectiveness of Just-A-Minute Optometry Clinical Pearls: a micro-learning tool in continuing optometry education.

CLINICAL RELEVANCE: Just-A-Minute Clinical Pearls as a microlearning concept may be beneficial in enhancing optometry and ophthalmology practice globally. BACKGROUND: Medical education often witnesses a gap in effectively translating the learnings into clinical practice, pointing to the complex and traditional teaching methods as hindrances. The present work studied the usefulness and acceptability of Just-A-Minute Optometry Clinical Pearls, a micro-learning tool, among optometrists and ophthalmologists. METHODS: Just-A-Minute Optometry clinical pearls were developed by the optometry team of…

Accuracy and feasibility with AI-assisted OCT in retinal disorder community screening.

Objective: To evaluate the accuracy and feasibility of the auto-detection of 15 retinal disorders with artificial intelligence (AI)-assisted … and retinal hemorrhage. Meanwhile, the diagnosis was also generated from three groups of individual ophthalmologists (group of retina specialists, senior ophthalmologists, and junior ophthalmologists) and compared with those by the AI. The area under the receiver operating characteristic curve (AUC), sensitivity, and specificity were calculated, and kappa statisti …

Screening for Ocular Candidiasis Among Patients With Candidemia: Is It Time to Change Practice?

Ocular candidiasis (OC) complicates approximately 10% of candidemia and carries potentially severe morbidity. There are conflicting recommendations about the need for routine funduscopic examinations of candidemic patients. Indirect funduscopy is accurate and safe in diagnosing OC, and positive findings change recommended treatment. However, conclusive evidence that treatment changes improve outcomes is lacking. Bringing perspectives as infectious diseases physicians and ophthalmologists, we review controversies about OC and endorse routine screening during candidemia. We acknowledge difficult…

[Correctly interpret the genetic testing results of inherited optic neuropathy].

Inherited optic neuropathy (ION), which can be characterized by isolated optic atrophy or together with systemic manifestations, is a rare optic nerve dysfunction with multiple genetic patterns. Genetic testing plays the key roles in the diagnosis, genetic counseling and treatment of ION. Currently, most ophthalmologists are unfamiliar with how to interpret the genetic testing results correctly. This article describes the genetic characteristics of ION and explains the main points on genetic reports interpretation to help ophthalmologists getting familiar with this relatively rare field and to…

Peripheral Ulcerative Keratitis Associated with Granulomatosis with Polyangiitis Emerging Despite Cyclophosphamide, Successfully Treated with Rituximab.

A 67-year-old Japanese man was diagnosed with granulomatosis with polyangiitis based on the presence of right maxillary sinusitis, proteinas … ulcerative keratitis newly emerged. We promptly switched the treatment from IVCY to rituximab, and ophthalmologists performed amniotic membrane transplantation, which avoided blindness. The close and effective working relationship between physicians and ophthalmologists improved our patient's ocular prognosis.