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Резюме докладов 2017 Ежегодное совещание Общества общей внутренней медицины.

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Электронные постеры

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Rapid Fire Presentations

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Gene editing and CRISPR in the clinic: current and future perspectives.

Genome editing technologies, particularly those based on zinc-finger nucleases (ZFNs), transcription activator-like effector nucleases (TALENs), and CRISPR (clustered regularly interspaced short palindromic repeat DNA sequences)/Cas9 are rapidly progressing into clinical trials. Most clinical use of CRISPR to date has focused on ex vivo gene editing of cells followed by their re-introduction back into the patient. The ex vivo editing approach is highly effective for many disease states, including cancers and sickle cell disease, but ideally genome editing would also be applied to diseases whic

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… to mesothelin with PD-1 knockout | Chinese PLA General Hospital | China | NCT03747965 | 11/20/2018 | Cas9 | I/II | Cytokine-induced SH2 protein (CISH) knockout | Metastatic gastrointestinal epithelial cancer | Ex vivo | Modified tumor infiltrating lymphocytes | Masonic Cancer Center, University of Minnesota …

The 45th Annual Meeting of the European Society for Blood and Marrow Transplantation: Physicians - Oral Session.

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Abstract

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Резюме книги: Тема: 13th Международный симпозиум на тему " Ходжкин лимфома " ; октябрь 2024

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… Friedberg 3 , Andrea Gallamini 4 , Massimo Federico 5 , Eliza Hawkes 6 , David Hodgson 7 , Peter Johnson 8 , Eric Mou 9 , Kerry Savage 10 , Pier Luigi Zinzani 11 , Andrew Evens 12 1 Mayo Clinic, Rochester, Minnesota, USA, 2 Tufts Medical Center, Boston, Massachusetts, USA, 3 University of Rochester …

American Society of Hematology 2026 guidelines on diagnosis of light chain amyloidosis.

BACKGROUND: Light chain (AL) amyloidosis is a rare disease caused by the misfolding of immunoglobulin light chains produced by a plasma cell dyscrasia. Patients can present with involvement of many organs, including the heart, kidneys, liver, nerves, and other sites, resulting in a high symptom burden. Timely and accurate diagnosis is important to prevent organ failure and improve patient survival. OBJECTIVE: These evidence-based guidelines of the American Society of Hematology (ASH) are intended to support patients and clinicians in the timely and effective diagnosis of AL amyloidosis. METH

Abstracts from the 37th Annual Meeting of the Society of General Internal Medicine, 2014, San Diego, CA, USA.

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Премии победителей и резюме 32nd Ежегодный симпозиум Общества протеинов; Бостон, ОЭТ, июль 9-12, 2018.

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… Constanzo 5 , Chad Myers 4 , Charles Boone 5 , Jose Florez 3 , Susan Lindquist 1 1 Whitehead Institute for Biomedical Research (Cambridge, United States); 2 Massachusetts Institute of Technology (Cambridge, United States); 3 Broad Institute of MIT and Harvard (Cambridge, United States); 4 University of Minnesota‐Twin …

Breaking into HIV-1's Epigenetic Vault: Cure Strategies to Eliminate the Viral Reservoir.

Human immunodeficiency virus type 1 (HIV-1) is a retrovirus that integrates into the host cell's DNA as a provirus. Transcription from the provirus is regulated in large part by cellular proteins and epigenetic factors. These may be repressive or permissive to productive infection. The host factors that regulate this balance are therefore attractive targets for HIV-1 therapeutics. Indeed, proviral chromatin is the focus of two of the current HIV-1 cure strategies. "Shock and Kill" uses latency reversal agents to open the provirus's chromatin, promoting high levels of gene expression that induc

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… To overcome these challenges, the Saluja group at the University of Minnesota developed Minnelide, a prodrug of triptolide with greater antitumorigenic effects [ 344 ]. Minnelide has since been the subject of a clinical trial to treat adenosquamous carcinoma of the pancreas [ 345 ]. …

Tumor-derived systems as novel biomedical tools-turning the enemy into an ally.

Cancer is a complex illness that presents significant challenges in its understanding and treatment. The classic definition, "a group of diseases characterized by the uncontrolled growth and spread of abnormal cells in the body," fails to convey the intricate interaction between the many entities involved in cancer. Recent advancements in the field of cancer research have shed light on the role played by individual cancer cells and the tumor microenvironment as a whole in tumor development and progression. This breakthrough enables the utilization of the tumor and its components as biological

2021 International Cancer Education Conference Program and Abstracts.

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… (Princess Margaret Cancer Centre) 3B-3 Casey Goldstein (University of Limerick School of Medicine) P103 Jordan Gomezpadilla (University of California San Diego) P45 Geenee Gonzales (San Diego State University) P97 Eduardo Gonzalez (UC San Diego Moores Cancer Center) P29 Amanda Gordon (University of Minnesota … Margaret Cancer Centre) | 3B-3 Casey Goldstein (University of Limerick School of Medicine) | P103 Jordan Gomezpadilla (University of California San Diego) | P45 Geenee Gonzales (San Diego State University) | P97 Eduardo Gonzalez (UC San Diego Moores Cancer Center) | P29 Amanda Gordon (University of Minnesota …

Abstracts of the Cell Therapy Transplant Canada 2024 Annual Conference.

On behalf of Cell Therapy Transplant Canada (CTTC), we are pleased to present the Abstracts of the CTTC 2024 Annual Conference. The conference was held on 1-3 May 2024 in beautiful Victoria, British Columbia, at the Victoria Conference Centre, and attracted 293 in-person delegates and five virtual attendees. Several plenary sessions were held on topics such as gene therapy for hemoglobin disorders, optimizing donor selection, graft-versus-host disease (GvHD) strategies, collaborative care, survivorship, graft failure, and CAR-T therapy. Poster authors presented their work during a lively and e

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… Vancouver, BC, Canada Department of Medicine, University of British Columbia, Vancouver, BC, Canada Michael Smith Laboratories, Department of Microbiology and Immunology, University of British Columbia, Vancouver, BC, Canada Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota …

Student Summer Research Awards - SSRAAbstracts of the SSRA September 2022 meeting, UCD School of Medicine.

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Материалы Международного общества по картированию раковых заболеваний (ИСИС) 18th Ежегодный учебный курс: Ментон, Франция. 7-9 октябрь 2018

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ISEV2021 Abstract Book

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Biology and Diseases of Dogs

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… The distribution of these cases is as follows: Northeast/mid-Atlantic focus, 85%; midwestern focus (Michigan, Wisconsin, Minnesota, Iowa, Illinois, and Missouri), 10%; and California and Oregon, 4%. …

Электронные постеры

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2023 Scientific Session of the Society of American Gastrointestinal and Endoscopic Surgeons (SAGES), Montréal, Canada, 19 March–April 1 2023: Posters

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