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Delirium in cancer patients admitted to the intensive care unit: a retrospective study.

ObjectiveTo describe the occurrence of delirium in cancer patients admitted to the intensive care unit according to clinical and demographic characteristics.MethodsA retrospective study was conducted with 135 adults admitted to the intensive care unit of a public cancer hospital in the city of Rio de Janeiro, Brazil, between January and March 2016. Fisher's exact test and the linear association test were used to identify statistically significant associations between the occurrence of delirium and categorical and ordinal variables, respectively, considering a p-value ResultsThe overall occurre

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… 23977818 10.2190/PM.45.2.d 18 Gagnon P Allard P Gagnon B Mérette C Tardif F Delirium prevention in terminal cancer: assessment of a multicomponent intervention Psychooncology 2012 21 2 187 194 22271539 10.1002/pon.1881 19 Gonzaléz M De Pablo J Valdés M Delirium: la confusión de los clínicos Rev Med Chile …

Rapid Fire

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Cancer mortality by country of birth and cancer type in Sweden: A 25-year registry-based cohort study.

Numerous studies have reported lower overall cancer mortality rates among immigrants compared to native populations. However, limited information exists regarding cancer mortality among immigrants based on specific birth countries and cancer types. We used population-based registries and followed 10 million individuals aged 20 years or older in Sweden between 1992 and 2016. The Cox proportional hazard model was used to explore the disparities in cancer mortality by country of birth and cancer type, stratified by gender. Age-standardized mortality rates were also computed using the world standa

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… Norway, Denmark), Non‐Nordic Europe (Turkey, Germany, Austria, Netherlands, France, former Yugoslavia, Bosnia‐Hercegovina, Italy, Spain, Greece, Croatia, Poland, Hungary, former Czechoslovakia, Romania, former Soviet Union, Russia, Estonia, UK and North Ireland), North America (USA), South America (Chile … 40. | 114.4 | 0.96 | 0.94 | 0.98 *** | 9833 | 42.9 | 80.5 | 0.93 | 0.91 | 0.95 ** North America USA | 485 | 1.4 | 107.0 | 0.94 | 0.86 | 1.03 | 405 | 1.3 | 82 | 0.87 | 0.79 | 0.96 ** All North America | 590 | 2.4 | 101.4 | 0.91 | 0.84 | 0.98 ** | 492 | 2.3 | 75.2 | 0.82 | 0.75 | 0.90 ** South America Chile …

Study of a novel Ca/P/S-based cement implanted in the osteoporotic goat spine and its clinical application in preventing adjacent vertebral fractures.

Osteoporotic vertebral compression fracture (OVCF) has been increasing over the last decades. In addition to primary OVCF, the adjacent vertebral fracture (AVF) is a frequent serious complication in OVCF patients receiving percutaneous vertebroplasty or kyphoplasty, resulting in poor long-term outcome and recurrent symptoms. The aim of the present study is to investigate the bone regeneration behavior of a novel Ca/P/S-based resorbable cement (Ezechbone® Cement CBC-400) implanted into surgically created vertebral defects of ovariectomized (OVX) goats. Furthermore, the present study provides a

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… Footnotes Edited by: Yaying Sun , Shanghai General Hospital, China Reviewed by: FuGuo Yang , Zigong First People’s Hospital, China Marcos Baabor , University of Chile, Chile Data availability statement The datasets presented in this article are not readily available because the datasets for this …

A multicountry ecological study of cancer incidence rates in 2008 with respect to various risk-modifying factors.

Observational and ecological studies are generally used to determine the presence of effect of cancer risk-modifying factors. Researchers generally agree that environmental factors such as smoking, alcohol consumption, poor diet, lack of physical activity, and low serum 25-hdyroxyvitamin D levels are important cancer risk factors. This ecological study used age-adjusted incidence rates for 21 cancers for 157 countries (87 with high-quality data) in 2008 with respect to dietary supply and other factors, including per capita gross domestic product, life expectancy, lung cancer incidence rate (an

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… Case-control study of arsenic in drinking water and kidney cancer in uniquely exposed Northern Chile Am. J. Epidemiol. 2013 178 813 818 10.1093/aje/kwt059 23764934 PMC3817454 128. Lopez-Abente G. Garcia-Perez J. Fernandez-Navarro P. Boldo E. Ramis R. … The other 70 countries: Algeria, Angola, Bangladesh, Benin, Bolivia, Botswana, Burkina Faso, Burundi, Cambodia, Cameroon, Cape Verde, Central African Republic, Chad, Chile, China, Comoros, Djibouti, Ethiopia, French Polynesia, Gabon, Gambia, Ghana, Guadeloupe, Guinea, Guinea-Bissau, Honduras, India, …

Sequential inactivated (IPV) and live oral (OPV) poliovirus vaccines for preventing poliomyelitis.

BACKGROUND: Poliomyelitis mainly affects unvaccinated children under five years of age, causing irreversible paralysis or even death. The or … . Ten RCTs were conducted in high-income countries; five in the USA, two in the UK, and one each in Chile, Israel, and Oman. The remaining six RCTs were conducted in middle-income countries; China, Bangladesh, Guatemala, India, and Thailand. We rated all included RCTs at low or unclear risk of bias for randomisation domains, most at high or unclear risk …

Direct Intercellular Communications and Cancer: A Snapshot of the Biological Roles of Connexins in Prostate Cancer.

Tissue homeostasis is the result of a complex intercellular network controlling the behavior of every cell for the survival of the whole organism. In mammalian tissues, cells do communicate via diverse long- and short-range communication mechanisms. While long-range communication involves hormones through blood circulation and neural transmission, short-range communication mechanisms include either paracrine diffusible factors or direct interactions (e.g., gap junctions, intercellular bridges and tunneling nanotubes) or a mixture of both (e.g., exosomes). Tumor growth represents an alteration

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… Department of Defense (W81XWH-12-1-0341); FONDECYT (1161115); ICM-Economía, Centro Interdisciplinario de Neurociencias de Valparaíso (P09-022-F); the Ligue contre le Cancer, Comités de la Charente-Maritime et de la Vienne; the French Embassy in Chile, Service of Cultural Cooperativity and Faculty of … Biological Science of the Pontificia Universidad Católica de Chile. …

Immunogenicity and shedding of live-attenuated intranasal respiratory syncytial virus vaccine in children aged 6-18 months by baseline serostatus: a multicentre, randomised, placebo-controlled, phase 1/2 trial.

BACKGROUND: Respiratory syncytial virus (RSV) causes acute respiratory illness in young children. The live-attenuated RSV vaccine candidate … his multicentre, randomised, placebo-controlled, phase 1/2 trial, children in the USA (N=22 sites), Chile (N=2 sites), and Honduras (N=2 sites) were recruited as participants. Healthy children aged 6-18 months at enrolment who were born at or after 34 weeks of gestation (if age 1 year or older) or children younger than 1 year at enrolment who were born …

In vitro расширила человека CD4+CD25+ регуляционные T клетки, подавляющие распространение Т клеток.

Регулирующие Т клетки (Tregs) оказались критически важными в балансе между автоиммунизацией и терпимостью и были связаны с несколькими аутоиммунными заболеваниями человека. Однако небольшое число трегов в периферии крови ограничивает их терапевтический потенциал. Поэтому мы разработали протокол, который позволит расширить "Трегз" при сохранении их подавляющей активности. Мы изолировали клетки CD4+CD25 hi от человеческой периферической крови и расширили их in vitro в присутствии anti-CD3 и anti-CD28 Магнитные кситы и высокие концентрации внешнего интерлейкина (IL) -2. Траги были эффективно расш

RESEARCH COMMUNICATIONS OF THE 28th ECVIM-CA CONGRESS.

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… canine leptospirosis in Switzerland correlates with the introduction of a new quadrivalent anti‐leptospiral vaccine 14.55‐15.10 | ISCAID‐O‐5 | López | Leptospira seroprevalence in owned dogs from Spain 15.10‐15.25 | ISCAID‐O‐6 | Dorsch | Urine shedding of pathogenic Leptospira spp. in cats in Southern Chile …

Non-cryopreserved Autologous Peripheral Blood Stem Cell Transplantation for Lymphoma in a Resource-Limited Setting: Feasibility, Engraftment Kinetics, and Early Outcomes From Kashmir, India.

Background  Autologous stem cell transplantation (ASCT) is a standard consolidation strategy for selected patients with relapsed or high-risk lymphoma, but access remains limited in many low- and middle-income regions because of the cost and infrastructure required for stem cell cryopreservation. Non-cryopreserved ASCT using fresh peripheral blood stem cells stored at 4°C may provide a practical alternative. Methods  We retrospectively analyzed 11 consecutive patients with lymphoma who underwent non-cryopreserved ASCT at the Department of Medical Oncology, Sher-i-Kashmir Institute of Medical S

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… Larger and more recent cohorts from India, Thailand, Algeria, and Chile have further supported the feasibility of refrigerated graft storage and reinfusion after lymphoma conditioning [ 14 , 15 , 17 , 19 ]. …

Judicialization of health: profile of demands for oncological medicines in a state in the central region of Brazil.

BACKGROUND: The significant increase in access to oncological medicines through court cases suggests that constitutional guarantees of integral and universal care in the Brazilian public health system are uncertain. METHODS: A retrospective observational study was conducted to analyze data from lawsuits requesting oncological medicines from 2014 to 2020 in the State of Goiás, Brazil, in state and federal courts. Sociodemographic, medical, and legal variables were statistically examined using descriptive, association, and correlation methods. RESULTS: Women brought more than half (54%) of the

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… In addition, using a judicial process to access health services also occurs in other countries, such as Chile, Colombia, and Costa Rica [ 3 – 5 ]. … When constitutional justice has the last word on health care: the case of Chile. Int J Health Serv. 2014;44(2):373–381. doi: 10.2190/HS.44.2.l. 6. Oliveira LCF, Nascimento MAA, Lima IM. Access to medication in universal health systems – perspectives and challenges. …

Research progress on arsenic, arsenic-containing medicinal materials, and arsenic-containing preparations: clinical application, pharmacological effects, and toxicity.

Introduction: The toxicity of arsenic is widely recognized globally, mainly harming human health by polluting water, soil, and food. However, its formulations can also be used for the clinical treatment of diseases such as leukemia and tumors. Arsenic has been used as a drug in China for over 2,400 years, with examples such as the arsenic-containing drug realgar mentioned in Shennong's Herbal Classic. We have reviewed references on arsenic over the past thirty years and found that research has mainly focused on clinical, pharmacological, and toxicological aspects. Results and Discussion: The f

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… Zhang et al. (2020b) found that air arsenic concentrations in 2005 were highest in Chile and eastern China, with mean values of 8.34 and 5.63 ng/m 3 , respectively. … A controlled study ( Ferreccio et al., 1998 ) in Chile found an association between bladder cancer and arsenic exposure. …

Global, regional, and national disability-adjusted life-years (DALYs) for 315 diseases and injuries and healthy life expectancy (HALE), 1990-2015: a systematic analysis for the Global Burden of Disease Study 2015.

BACKGROUND: Healthy life expectancy (HALE) and disability-adjusted life-years (DALYs) provide summary measures of health across geographies and time that can inform assessments of epidemiological patterns and health system performance, help to prioritise investments in research and development, and monitor progress toward the Sustainable Development Goals (SDGs). We aimed to provide updated HALE and DALYs for geographies worldwide and evaluate how disease burden changes with development. METHODS: We used results from the Global Burden of Diseases, Injuries, and Risk Factors Study 2015 (GBD 20

Е-постеры.

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Измерять ионизирующую фракцию в самолете от массивного протостара.

Важно определить, образуются ли массивные звезды через аккрецию диска, как и их низкомассовые аналоги. Теория и наблюдения указывают на то, что протозвезды являются естественным следствием аккреционных дисков и, вероятно, имеют решающее значение для устранения углового импульса во время краха. Однако массивные протостары, как правило, более редкие, более отдаленные и более окутанные пылью, что затрудняет проведение наблюдений за их реактивными самолетами. Один из основополагающих вопросов заключается в том, является ли степень ионизации в реактивных самолетах одинаковой во всем массовом спектр

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… Methods NIR VLT/ISAAC imaging and spectroscopy NIR imaging was obtained on 2013 July 7 in the K and H 2 bands with the ISAAC instrument on VLT (ESO, Chile). … This research is based on observations collected at the VLT (ESO Paranal, Chile) with programme IDs 290.C-5060(A) and 290.C-5060(B). This research is based on observations made with the NASA/ESA Hubble Space Telescope with proposal identifier: 14465. The Karl G. …

Прогресс в лечении множественной миеломы.

Множественная миелома (ММ) является вторым по распространенности гематологической злокачественности в мире. Несмотря на свою репутацию агрессивного и смертельного заболевания, недавние улучшения в лечении значительно улучшили результаты лечения. За последнее десятилетие появились инновационные методы лечения с меньшим числом побочных эффектов, включая протеиновые ингибиторы (например, борцезомиб, карфилзомиб, ixazomib), моноколональные антитела (например, даратумумаб, изатуксимаб, элотузумаб), иммуномуляторы (например, талидомид, линалидомид, помалидомид) и кортикостероиды (например, дексамета

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… [Article in Spanish] Rev Médica Chile Conte G Braggio E Figueroa G Fonseca R 552 558 137 2009 19623423 10 Multiple myeloma: 2022 update on diagnosis, risk stratification, and management Am J Hematol Rajkumar SV 1086 1107 97 2022 35560063 10.1002/ajh.26590 PMC9387011 11 Utilidad de pruebas de laboratorio …

Cell Count Differentials by Cytomorphology and Next-Generation Flow Cytometry in Bone Marrow Aspirate: An Evidence-Based Approach.

Despite a lack of evidence, a bone marrow aspirate differential of 500 cells is commonly used in the clinical setting. We aimed to test the performance of 200-cell counts for daily hematological workup. In total, 660 consecutive samples were analyzed recording differentials at 200 and 500 cells. Additionally, immunophenotype results and preanalytical issues were also evaluated. Clinical and statistical differences between both cutoffs and both methods were checked. An independent control group of 122 patients was included. All comparisons between both cutoffs and both methods for all relevant

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… Técnicas y Procedimientos de Laboratorio Mediterráneo Santiago, Chile 1996 240 9562201155 6. Perkins S.L. Examination of the blood and bone marrow Wintrobe’s Clinical Hematology 11th ed. Greer J.P. Foerster J. Lukens J.N. …

Effectiveness of Resistance Training on Fatigue in Patients Undergoing Cancer Treatment: A Meta-Analysis of Randomized Clinical Trials.

ObjectiveTo assess the effectiveness of the resistance training to improve fatigue levels in people with cancer who are enrolled in adjuvant and/or neoadjuvant treatment.MethodsMEDLINE, Web of Science, Embase, SPORTDiscus, LILACS, CENTRAL, and CINAHL databases were searched from May to December 7, 2021. Randomized clinical trials (RCT) that evaluate the effects of resistance training on fatigue levels in people undergoing cancer treatment were included. The PEDro scale was considered to assess methodological quality of studies, and the evidence was summarized through the GRADE system. The stan

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… The GRADE system: a change in the way of assessing the quality of evidence and the strength of recommendations Revista Médica de Chile 2014 142 5 630 635 10.4067/S0034-98872014000500012 2-s2.0-84906826708 25427021 28 Cheng D. Wang X. Hu J. …

Oral Presentations

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… Sótero del Rio, Santiago, Chile 5 Hospital La Fe, Valencia, Spain Introduction: Scoliosis correction procedures in children are technically demanding and complex surgeries that can lead to several complications. … management and post-operative opioid consumption in spine surgery patients remain challenging topics that deserve further study. 1877 A024: The Use of Telemedicine for Orthopedic Pathology During the COVID-19 Pandemic Karen Weissmann 1 2 , Marcelo Perez 1 , and Francoise Descazeaux 1 1 MEDS, Santiago, Chile …