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Воздействие питательных микроэлементов на результаты беременности в развивающихся странах: систематический обзор и метаанализ.

СПРАВОЧНАЯ ИНФОРМАЦИЯ: В развивающихся странах по-прежнему относительно высоки показатели низкой беременности. Недостаток питательных микроэлементов относится к числу факторов, которые играют определенную роль в определении негативных последствий беременности. Цель настоящего исследования заключается в изучении роли дефицита питательных микроэлементов в неудовлетворительных результатах беременности и их связи с здоровьем новорожденных.МЕТОД: Для этого обзора был проведен систематический поиск с использованием программы " Харзинг периш " и публикация программного обеспечения, а также

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… Single studies were additionally conducted in Kenya ( n = 1), Benin ( n = 1), South Africa ( n = 1), Indonesia ( n = 1), and Guinea-Bissau ( n = 1). … Indonesia Double-blind randomized controlled trial 31,290 18% reduction in adverse outcomes in MMS group vs. iron–folic acid 18 Low Moderate [ 73 ] Fawzi WW et al. …

Воздействие упражнений на движение в сочетании с методами дыхания на торакический угл кифоза у лиц с торакическим гиперкифозом: систематический обзор и мета-анализ.

Теоретический гиперкифоз (THK) — посттуральная деформация, связанная с болью, расстройством дыхательных путей, снижением качества жизни, повреждением лопаточного ритма, биомеханическими изменениями плеча и повышенным риском падения. Хотя упражнения по исправлению положения широко используются, дополнительная ценность интеграции конкретных методов дыхания остается неясной. Цель этого систематического обзора и метаанализа состояла в том, чтобы оценить воздействие двигающихся упражнений в сочетании с дыхательными методами на угол торакического кифоза (TKA) у отдельных лиц с помощью THK.MetodsA си

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… The included studies were conducted across three countries: Egypt (n = 2), Iran (n = 2), and Indonesia (n = 1). Among the five studies [ 17 , 18 , 30 , 31 , 32 ], three were RCTs conducted in Iran (n = 1) and Egypt (n = 2), while two were non-RCTs conducted in Indonesia (n = 1) and Iran (n = 1). … Munawwarah et al. (2023) Indonesia [ 18 ] | Non- RCT | N: 22 Sex: female Age: 59.9 ± 3.3 years | Flexible ruler Baseline kyphosis value: 54.4 | D: 5 weeks F: NR I: NR Ti: NR T: combined deep breathing exercise with postural training | D: 5 weeks F: NR I: NR Ti: NR T: postural training | TKA | The changes …

Меры по оказанию помощи в случае хронических заболеваний, основанные на группировании: систематический обзор случайных контролируемых испытаний.

Растущее глобальное бремя хронических заболеваний требует новых и интерактивных и устойчивых мер. Гамификация стала новаторской стратегией, направленной на более активное вовлечение пациентов в лечение хронических заболеваний и их самостоятельное лечение. Хотя gamification широко используется в сфере здравоохранения, анализ данных о ее эффективности в различных клинических условиях остается непоследовательным. three основные базы данных: EBSCOhost, PubMed и Scopus вместе с two поисковые системы, включая Google Scientific and Sage Journal, без ограничений по годам, после PRISMA 2020 и методолог

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… The trials were conducted in various countries, with the United States contributing the most studies (4 in total). 24–27 Other studies were conducted in Indonesia, Pakistan, Poland, Canada, Turkey, Brazil, Switzerland, Italy, the Netherlands, and China. … Acknowledgments All authors would like to thank Padjadjaran University, Bandung, West Java, Indonesia, for facilitating the database and funding this research. Disclosure The authors report no conflicts of interest in this work. References 1. Koehlmoos TP, Anwar S, Cravioto A. …

Витамин К: Инфекция, воспаление и автоиммунитет.

Витамин К (VK) состоит из группы веществ с биоактивностью хлорофилла квинона и существует в природе в виде VK1 и VK2. Так как его первоначальное распознавание было основано на способности поощрять коагуляцию крови, он известен как витамин коагуляции. Однако, основываясь на обширных исследованиях, VK продемонстрировал потенциал в области профилактики и лечения различных заболеваний. В последние годы растет интерес к исследованиям, демонстрирующим благотворное воздействие ВК на иммунитет, способность к антиоксидантам, регулирование кишечника микробиота, развитие эпителии и защиту костей. В этой

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… Intervention Exposure Effect of Intervention on Illness Shiraki et al 2000 Japan 93 241 PMO 67.2 y Prospective 2y 45 mg/d MK-4 vs control ↓ ucOC ↑cOC ↓ fracture risk Iwamoto et al 2001 Japan 94 72 PMO 65.3 y Prospective 2 y 45 mg/d MK-4 + Ca vs Ca ↓ vertebral fractures ↑BMD (forearm) Purwosunu et al 2006 Indonesia … Intervention Exposure Effect of Intervention on Illness Shiraki et al 2000 Japan 93 241 PMO 67.2 y Prospective 2y 45 mg/d MK-4 vs control ↓ ucOC ↑cOC ↓ fracture risk Iwamoto et al 2001 Japan 94 72 PMO 65.3 y Prospective 2 y 45 mg/d MK-4 + Ca vs Ca ↓ vertebral fractures ↑BMD (forearm) Purwosunu et al 2006 Indonesia …

Оценка прогнозируемых факторов, которые сокращают продолжительность лечения пациентов с множественной миеломой с использованием AI: Реальное продольное исследование в мире с использованием данных из базы данных о перспективах медицинских данных.

С учетом наличия новых методов лечения продолжительность терапии (DOT) сокращается с каждым увеличением линии лечения японских пациентов с множественной миеломой (MM). Цель этого исследования заключалась в выявлении факторов, которые сокращают DT у пациентов с MM с использованием процедуры машинного обучения (ML) из базы данных Medical Data Vision (MDV). 2003 в адрес 2022. Пациенты≥18 y) с недавно поставленным диагнозом MM, имеющим право на трансплантацию (продолжение первой линии терапии), или с рецидивом или рефракторным MM (продолжение второй или третьей строки терапии). Для выявления важны

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… PONE-D-21-20512 35476849 PMC9045668 41 Marutho D Handaka SH Wijaya E Muljono The determination of cluster number at k-mean using elbow method and purity evaluation on headline news 2018 2018 International Seminar on Application for Technology of Information and Communication 2018 Sep 21-22 Semarang, Indonesia … Proceedings of the 2nd Workshop on Multidisciplinary and Applications (WMA) , January , Padang, Indonesia; 2020 2018 Padang, Indonesia 10.4108/eai.24-1-2018.2292388 43 Hassan BA Rashid TA Hamarashid HK A novel cluster detection of COVID-19 patients and medical disease conditions using improved evolutionary …

Interventions for improving coverage of childhood immunisation in low- and middle-income countries.

BACKGROUND: Immunisation plays a major role in reducing childhood morbidity and mortality. Getting children immunised against potentially fa … orgia, Mexico, Guatemala), 11 lower-middle-income countries (Côte d'Ivoire, Ghana, Honduras, India, Indonesia, Kenya, Nigeria, Nepal, Nicaragua, Pakistan, Zimbabwe), and three lower-income countries (Afghanistan, Mali, Rwanda). The interventions evaluated in the studies were health education (seven studies), patient reminders (13 studies), digital register …

Anti-vascular endothelial growth factors in combination with vitrectomy for complications of proliferative diabetic retinopathy.

BACKGROUND: Vitrectomy is an established treatment for the complications of proliferative diabetic retinopathy (PDR). However, a number of c … m Mexico and the remaining studies from South Korea, the UK, Egypt, Brazil, Japan, Canada, the USA, Indonesia and Pakistan). The inclusion criteria for entry into the studies were the well-recognised complications of proliferative retinopathy: non-clearing vitreous haemorrhage, tractional retinal detachment involving the macula or combined tractional rhegma …

Emerging advances in drug delivery systems (DDSs) for optimizing cancer complications.

The management and treatment of tumor complications pose continuous challenges due to the inherent complexity. However, the advent of drug delivery systems (DDSs) brings promising opportunities to address the tumor complications using innovative technological approaches. This review focuses on common oncological complications, including cancer thrombosis, malignant serous effusion, tumor-associated infections, cancer pain, and treatment-related complications. Emphasis was placed on the application and potential of DDSs in mitigating and treating these tumor complications, and we delved into th

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… | Indonesia University NCT06073496 | Completed | Gynecologycal Cancer | Electroacupuncture | NA | Indonesia | Indonesia University NCT05317026 | Recruiting | Spine Metastases | Vertebroplasty plus Stereotactic Body Radiation Therapy | NA | Montréal, Quebec, Canada | Centre hospitalier de l'Université … | Indonesia University NCT05870241 | Completed | Post Mastectomy Lymphedema | Ga-As Laser/Microcurrent Electrical Stimulation | NA | Giza, Egypt | Cairo University NCT06223659 | Recruiting | Skin cancers | Eutectic Mixture of Local Anesthetics | II | Columbus, Ohio, United States | Ohio State University …

Crowdfunding for complementary and alternative medicine: What are cancer patients seeking?

BackgroundComplementary and alternative medicine (CAM) is increasingly being integrated into conventional medical care for cancer, used to counter the side effects of conventional cancer treatment, and offered as an alternative to conventional cancer care. Our aim is to gain a broader understanding of trends in CAM interventions for cancer and crowdfunding campaigns for these interventions.MethodsGoFundMe campaigns fundraising for CAM were retrieved through a database of crowdfunding campaign data. Search terms were drawn from two National Institutes of Health lists of CAM cancer interventions

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… Australia | 3 | 0.63 Philippines | 3 | 0.63 Austria | 2 | 0.43 China | 2 | 0.43 Czech Republic | 2 | 0.43 Hungary | 2 | 0.43 India | 2 | 0.43 Jamaica | 2 | 0.43 Japan | 2 | 0.43 Latvia | 2 | 0.43 New Zealand | 2 | 0.43 Switzerland | 2 | 0.43 Brazil | 1 | 0.21 Costa Rica | 1 | 0.21 Ecuador | 1 | 0.21 Indonesia … Australian-based campaigns sought interventions in Mexico (n = 6, 30.0%), Thailand (n = 4, 20.0%), Australia (n = 3, 15.0%), New Zealand (n = 2, 10.0%) and 1 each for Ecuador, Germany, Indonesia, Jamaica, and the US. …

Систематический обзор эпидемиологии и вариантов лечения нескольких миелом в Азии.

Множественная миелома (ММ) почти 15 % из всех неопластических магнатов по всему миру. Целью этого систематического обзора является анализ данных об обработке и управлении ММ в отдельных регионах Азии в целях выявления и приоритизации областей, требующих внимания. Всеобъемлющий обзор оригинальных статей, опубликованных на английском языке 2005 в адрес 2022, почерпнутые из базы данных PubMed/MedLINE, были проведены на основе руководящих принципов, касающихся предпочтительных элементов отчетности для системных обзоров и мета-анализов (PRISMA). Там были 98 - исследования из отдельных регионов Азии

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… OR (refractory)) AND ((Taiwan) OR (Hong Kong) OR (Malaysia) OR (Singapore) OR (Indonesia) OR (India) OR (China) OR (Asia))) NOT ((case report) OR (consensus) OR (review) OR (news))). … Geographical restrictions were applied to limit the search to specific regions (Taiwan, Hong Kong, China, Malaysia, Singapore, Indonesia, and India). The search strategy was designed and reviewed independently for coverage and accuracy. …

Стратегии охраны мозга у лиц среднего возраста с незначительным нейрокогнитивным расстройством: аналитическая оценка.

Здравоохранение мозга означает оптимальное функционирование и целостность мозга, определяемые сложными когнитивными, психологическими и социальными детерминантами. Лица с легким нейрокогнитивным расстройством (mNCD) подвергаются повышенному риску развития слабоумия. Первостепенное состояние мозга имеет важное значение на протяжении всей жизни, особенно в период среднего возраста, когда риск для здоровья часто возникает наряду с тяжелыми жизненными обязанностями. В международных рамочных программах особое внимание уделяется изменению факторов риска на протяжении всей жизни в целях снижения риск

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… Fitriana et al., 2020 | Indonesia | Quasi-experimental, pre-post with control | Research university setting | Community-dwelling individuals | n = 32 | 44–61 years | Aerobic: 51.88±4.17 years Control: 51.75±4.95 years | To determine the effect of a 16-week aerobic exercise regimen on cognition, physical … | 2 urban community settings in Indonesia | Indonesian language; ethnicity not specified | Not reported | 100% female | Not reported | Recorded as low (elementary/ junior high) vs high (senior high/ university) | Not reported | Marital status collected, but not reported | Age included Bampa et al., …

Larvivorous fish for preventing malaria transmission.

BACKGROUND: Adult female Anopheles mosquitoes can transmit Plasmodium parasites that cause malaria. Some fish species eat mosquito larvae an … dy), Kenya (two studies), Sudan (one study), Grande Comore Island (one study), Korea (two studies), Indonesia (one study), and Tajikistan (two studies). These studies were conducted in a variety of settings, including localized water bodies (such as wells, domestic water containers, fishponds, and pools (seven studies); riverbed pools below dams (two studie …

Rigid dressings versus soft dressings for transtibial amputations.

BACKGROUND: Dressings are part of the routine postoperative management of people after transtibial amputation. Two types of dressings are co … ants from acute and/or rehabilitation hospitals from seven different countries (the USA, Australia, Indonesia, Thailand, Canada, France and the UK). In all but one study, it was clearly stated that amputations were secondary to vascular conditions.Primary outcomes Wound healing We are uncertain whether rigid dressings decrease the time to wound healing comp …

Photobiomodulation therapy on chemo- and radiotherapy induced oral conditions: an umbrella review.

ObjectivesPhotobiomodulation (PBM) is a laser-based therapy used to promote tissue repair, reduce inflammation and pain, and has been extensively studied in chemo- and radiotherapy-induced oral mucositis (OM). This review examines the level of evidence of systematic reviews (SRs) that have investigated PBM in such cases of OM.Materials and methodsSRs evaluating PBM for both the treatment and prevention of OM in patients undergoing chemotherapy and/or radiotherapy and published before November 30, 2023, on PubMed, Cochrane, Embase, Web of Science, LILACS, TRIP and Open Grey databases were eligi

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… Studies characteristics Overall, these SRs were mainly produced in Brazil ( n = 8) [ 12 , 23 , 25 , 27 , 31 , 36 , 42 ], China ( n = 2) [ 26 , 34 ] and the United Kingdom ( n = 2) [ 33 , 37 ], with contributions from groups in Canada [ 24 ], Iran [ 28 ], Israel [ 29 ], Indonesia [ 39 ], Malaysia [ 35 … None Danwiek et al. (2023) [ 39 ] (Indonesia) Adults NR 47 (only referenced 43 studies) PRISMA Cochrane ROB and JBI Tools Before Jun 2021 LLLT is most effective in reducing OM degree and associated pain. …

Global perspectives on lupus nephritis: a review of clinical trials and therapeutic innovations.

BACKGROUND AND OBJECTIVES: Lupus nephritis (LN) remains a leading cause of morbidity and mortality in systemic lupus erythematosus (SLE). Although recent years have witnessed the approval of several targeted therapies, achieving long-term, drug-free remission remains challenging. This commentary evaluates the global landscape of interventional LN clinical trials from 2001 to 2026 to identify emerging trends and strategic gaps in drug development. METHODS: We analyzed 200 interventional pharmacological trials retrieved from three major global registries: ClinicalTrials.gov, Chinadrugtrials.org

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… NCT00094380 (Completed) | Phase I, II | 2004 | CTLA4-IgG4m (RG2077)+CTX | United States | III, IV, V NCT00089804 (Terminated) | Phase III | 2004 | Abetimus sodium (LJP 394) | United States, Argentina, Australia, Belarus, Brazil, Bulgaria, Czechia, Georgia, Germany, Hong Kong (China), Hungary, India, Indonesia … Edited by: Charalampos Skarlis , University of Nicosia, Greece Reviewed by: Arriel Makembi Bunkete , Centre Hospitalier de l’Ouest Guyanais, French Guiana Faisal Parlindungan , University of Indonesia, Indonesia Data availability statement The original contributions presented in the study are included …

The Out-of-Pocket Cost Burden of Cancer Care-A Systematic Literature Review.

BackgroundOut-of-pocket costs pose a substantial economic burden to cancer patients and their families. The purpose of this study was to evaluate the literature on out-of-pocket costs of cancer care.MethodsA systematic literature review was conducted to identify studies that estimated the out-of-pocket cost burden faced by cancer patients and their caregivers. The average monthly out-of-pocket costs per patient were reported/estimated and converted to 2018 USD. Costs were reported as medical and non-medical costs and were reported across countries or country income levels by cancer site, where

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… Figure 6 summarizes these estimates per study and country income-level and presents a weighted average for HICs (U.S., Canada, Australia) and LMICs (China, Malaysia, India, Haiti, Brunei, Thailand, Indonesia, Philippines, Vietnam, Laos, Cambodia, Myanmar). … Studies conducted in low- and middle-income countries include China, Malaysia, India, Haiti, Brunei, Thailand, Indonesia, Philippines, Vietnam, Laos, Cambodia, and Myanmar. Equity considerations and distributional effects were explicitly evaluated by a third of the included studies ( n = 32). …

Impact of population ageing on cancer-related disability-adjusted life years: A global decomposition analysis.

BACKGROUND: As the global population ages, the burden of cancer is increasing. We aimed to assess the impact of population ageing on cancer-related disability-adjusted life years (DALYs). METHODS: We used the decomposition method to estimate the impact of ageing, population growth, and epidemiological change on cancer-related DALYs from 1990 to 2019, stratified by 204 countries/territories and by their sociodemographic index (SDI). This approach separates the net effect of population ageing from population growth and change in age-specific DALY rates. RESULTS: Cancer-related DALYs among indi

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… | 240.03 | China | 157.20 | China | 84.96 2 | USA | 32.69 | USA | 22.36 | India | 15.84 3 | India | 30.60 | Japan | 20.54 | USA | 12.20 4 | Japan | 28.74 | India | 14.44 | Japan | 10.02 5 | Brazil | 15.60 | Russian Federation | 10.74 | Brazil | 7.20 6 | Russian Federation | 12.88 | Germany | 9.21 | Indonesia … | 5.61 7 | Republic of Korea | 11.06 | Brazil | 8.27 | Thailand | 4.38 8 | Germany | 10.97 | Republic of Korea | 8.16 | Russian Federation | 4.31 9 | Indonesia | 10.32 | France | 6.59 | Republic of Korea | 3.61 10 | Thailand | 10.31 | Italy | 6.39 | Germany | 3.48 195 | Somalia | −0.09 | Burkina Faso …

Single Nucleotide Polymorphisms in XMN1-HBG2, HBS1L-MYB, and BCL11A and Their Relation to High Fetal Hemoglobin Levels That Alleviate Anemia.

Anemia is a condition in which red blood cells and/or hemoglobin (Hb) concentrations are decreased below the normal range, resulting in a lack of oxygen being transported to tissues and organs. Those afflicted with this condition may feel lethargic and weak, which reduces their quality of life. The condition may be manifested in inherited blood disorders, such as thalassemia and sickle cell disease, whereas acquired disorders include aplastic anemia, chronic disease, drug toxicity, pregnancy, and nutritional deficiency. The augmentation of fetal hemoglobin (HbF) results in the reduction in cli

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… In Indonesia, the HbF expression is slightly higher, at 3.2%, and it is even higher in Syria, at 16.3% [ 39 , 42 , 59 ]. 3.2. … Modifying effect of XmnI, BCL11A, and HBS1L-MYB on clinical appearances: A study on β-thalassemia and hemoglobin E/β-thalassemia patients in Indonesia Hematol. Oncol. Stem Cell Ther. 2016 9 55 63 10.1016/j.hemonc.2016.02.003 27009595 42. Yusof W. Zulkifli M.M. Azman N.F. Ab Hamid S.A. Othman A. …