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Macular edema and pregnancy in insulin-dependent diabetes.

Seven women with insulin-dependent diabetes (mean age, 26 years; mean duration of diabetes, 15.4 years) had minimal or no retinopathy before … gnificant visual loss. Pregnant women with retinopathy, nephropathy, or hypertension should undergo ophthalmoscopy at least once a month. If proliferative retinopathy develops, panretinal photocoagulation should be applied even if the macular edema is aggravated.

Fundus changes following faden operation.

A faden operation was performed in 187 eyes that were studied by indirect binocular ophthalmoscopy at regular intervals after the surgical procedure. Of these eyes, 29 (15.5%) showed ocular fundus abnormalities, with 28 cases of chorioretinal scars at the level of the muscle scleral anchorage and one case of Herpburn-Amalric triangular syndrome of choroidal ischemia. No case of retinal tears was found in this series. Fundus changes are by far the most frequent complication of the faden operation, and to our knowledge, this has not been previously described. The findings of the present study su…

Epibulbar lesions simulating extraocular extension of uveal melanomas.

Twelve patients who were referred to the Oncology Service of Wills Eye Hospital, Philadelphia, with a pigmented epibulbar lesion that clinic … us, and ocular melanocytosis accounted for the other three conditions. A thorough history, indirect ophthalmoscopy with scleral depression, ultrasonography, gonioscopy, and transillumination were helpful in distinguishing uveal malignant melanoma with extrascleral extension from other, often less serious, ophthalmic disorders.

Leber's optic neuropathy: clinical and visual evoked response studies in asymptomatic and symptomatic members of a 4-generation family.

A clinical and neuro-ophthalmological examination using tests of visual acuity, quantitative visual field analysis, tests of colour discrimination, ophthalmoscopy, and pattern visual evoked responses was performed on 2 symptomatic and 16 asymptomatic members of a family with Leber's optic neuropathy. The visual evoked responses were abnormal in the 2 clinically affected males and in 1 asymptomatic male. Tests of colour discrimination with Ishihara plates, the Farnsworth-Munsell 100 hue test, and the Nagel anomaloscope revealed abnormalities in 8 asymptomatic family members, with the Farnsworth…

Корь ретинопатия во время иммунодепрессии.

У 14-летнего мальчика был острый приступ кори во время цитотоксичной химиотерапии в связи с новообразованием яичек. Два месяца спустя была разработана смертельная энцефалопатия кори, подтвержденная гистологическими, ультраструктурными и иммунофтористими исследованиями. Офтальмоскопия показала прогресс в плоской депигментированной области сетчатки, а также значительные повреждения, имитирующие центральную серозовую ретинопатию или ретинит. Гистопатологические исследования показали фокусные некрозы сетчатки с вторжением в сетчатку макрофаги с погружением в пигмент. В хороиде не было провокационн

Совпадение в аннотации оригинала
A 14-year-old boy had an acute attack of measles while on cytotoxic chemotherapy for a testicular neoplasm. Two months later a fatal measles encephalopathy developed, verified by histological, ultrastructural, and immunofluorescent studies. Ophthalmoscopy showed progression of flat depigmented areas of the retina as well as prominent lesions mimicking centra…

Closed vitreous surgery: XV. Fibrovascular ingrowth from the pars plana sclerotomy.

Ten eyes developed fibrovascular ingrowth from the sclerotomy following closed vitreous surgery. The complication was detected by examining all patients postoperatively by indirect ophthalmoscopy and biomicroscopy with a three-mirror lens. The average follow-up was 13.2 months. Nine patients had proliferative retinal disease prior to surgery and related systemic disease. In six eyes, useful vision was lost due to the ingrowth. In three eyes, a stabilization occurred. In one eye, that of a 12-year-old girl with an undefined syndrome of cochlear and retinal neovascularization, the ingrowth invol…

Clinical analysis of Leber's hereditary optic neuropathy harboring mtDNA mutation at nt11778.

PURPOSE: To improve our diagnostic technique through the analysis of clinical features of Leber's hereditary optic neuropathy (LHON) harboring mtDNA point mutation at nt11778. METHODS: Detection of nt11778 mutation was performed on 38 patients clinically diagnosed as LHON in our ophthalmic center from year 1998 to 2000. Circumstances of onset and family history were obtained and ophthalmoscopy, fundus fluorescein angiography, visual field and visual evoked potential were performed on all 38 patients. RESULT: 30 In 38 patients (78.95%) harbor nt11778 mutation, including 28 male (93.33%) and 2…

Pediatric Eye Screening: Current Standards and Gaps in Care.

The nonmydriatic, noncontact, and rapid acquisition features of ultra-widefield fundus (UWF) imaging create an invaluable tool for pediatric retinal screening in primary care. This review assesses the landscape of pediatric eye screening, identifies gaps in diagnosing a range of pediatric retinal conditions, and discusses potential uses of UWF imaging for retinal screening. The standards for pediatric eye screening in primary care include red reflex testing, direct ophthalmoscopy, external ocular exam, instrument-based screening, and visual acuity testing. These tests fail to diagnose several …

Correction Method for Optical Scaling of Fundoscopy Images: Development, Validation, and First Implementation.

PURPOSE: Although fundus photography is extensively used in ophthalmology, refraction prevents accurate distance measurement on fundus images, as the resulting scaling differs between subjects due to varying ocular anatomy. We propose a PARaxial Optical fundus Scaling (PAROS) method to correct for this variation using commonly available clinical data. METHODS: The complete optics of the eye and fundus camera were modeled using ray transfer matrix formalism to obtain fundus image magnification. The subject's ocular geometry was personalized using biometry, spherical equivalent of refraction (R

Automated vertical cup-to-disc ratio determination from fundus images for glaucoma detection.

Glaucoma is the leading cause of irreversible blindness worldwide. Often asymptomatic for years, this disease can progress significantly before patients become aware of the loss of visual function. Critical examination of the optic nerve through ophthalmoscopy or using fundus images is a crucial component of glaucoma detection before the onset of vision loss. The vertical cup-to-disc ratio (VCDR) is a key structural indicator for glaucoma, as thinning of the superior and inferior neuroretinal rim is a hallmark of the disease. However, manual assessment of fundus images is both time-consuming a…

Retinal Artery Angles in High Axial Myopia and Its Relationship With Visual Function.

PURPOSE: To evaluate the retinal artery angles in high axial myopia and assess the correlation with other morphometric and functional parameters. METHODS: This cross-sectional study included 112 eyes of 112 patients with high axial myopia. Based on axial length (AL), the participants were divided into three groups: group 1 (26 ≤ AL < 28 mm), group 2 (28 ≤ AL < 31 mm), and group 3 (≥31 mm). Scanning laser ophthalmoscopy imaging was used to analyze the retinal artery angle (Yugami correlated angle [YCA]). Retinal vascular densities (VDs) in both superficial capillary plexuses (SCPs) and deep ca…

Ultra-Widefield Imaging for Pediatric Retinal Disease.

This article explores the development of retinal imaging, with particular emphasis on ultra-widefield imaging and the key concept of field of view. Two ultra-widefield imaging platforms are examined in detail-Optomap and Spectralis-noncontact imaging systems that include protocols for performing angiography in infants. Applications of ultra-widefield imaging are illustrated using case studies, including diagnosis, monitoring, and screening.

In vivo retinal vascular cannulation in rabbits.

PURPOSE: To perform in vivo cannulation of retinal vessels for local application of pharmacotherapy to treat central retinal vein occlusion … easing intraocular pressure by elevating the infusion bottle. Postoperative observation by indirect ophthalmoscopy showed no obstruction in the vein at the puncture site. Light microscopy showed only a slight narrowing of the venous lumen at the site. CONCLUSION: Cannulation into the retinal vein of rabbits was possible, and invasion was not significant, as det …

Ophthalmic manifestations of the acquired immunodeficiency syndrome.

1. Ophthalmic manifestations of AIDS involve both anterior and posterior segments and can result in total loss of vision. Understanding of these ocular manifestations has become more important as this disease continues to proliferate. 2. Although the risk of infection by HIV in the ophthalmic setting is remote, ophthalmic health-care workers may come in contact with potentially infectious fluids in the course of normal ocular examination procedures. Infection control procedures are therefore recommended. 3. If health-care workers experience a possible exposure, they should consult a physician

Central serous chorioretinopathy associated with pregnancy.

Central serous chorioretinopathy is an infrequent but benign complication of pregnancy that is found largely in the minority population. White subretinal exudates and multiple recurrences are frequently seen with the central serous chorioretinopathy of pregnancy. Central serous chorioretinopathy usually spontaneously resolves with minimal sequelae without intervention after delivery of the baby.

Aphakic and pseudophakic spectacle management.

Refracting glasses and clips eliminate the many vertex distance-pantoscopic tilt pitfalls found in aphakic and pseudophakic visual examination. The amount of asphericity used in the prescribed aphakic lens enables the patients to function normally in his environment. Keratometry readings display the surgical wound healing process. Absorption tints are prescribed to reduce the amount of harmful ultraviolet rays from entering the human eye.