Результаты поиска

Автохтонное сеульское вирусное заражение у женщины с острыми почечными травмами.

За пределами Азии вирус Сеула (SEOV) является недооцененным патогеном. В Германии болезнь хантавируса, связанная с автохтонным синдромом SEOV, не диагностирована однозначно. Мы нашли клинические и молекулярные доказательства инфекции SEOV у молодой женщины; ее крыса была источником инфекции.

Совпадение в аннотации оригинала
Outside Asia, Seoul virus (SEOV) is an underestimated pathogen. In Germany, autochthonous SEOV-associated hantavirus disease has not been unequivocally diagnosed. We found clinical and molecular evidence for SEOV infection in a young woman; her pet rat was the source of infection.

[45 years of microsurgery in urology : Contemporary witnesses report with special reference to vasectomy reversal].

On the occasion of the 45th anniversary of the introduction of microsurgery in urology, the author describes the historical development of urologic microsurgery in Germany, with special reference to vasectomy reversal. Together with contemporary witnesses, a critical historical review is drawn and the current status is analyzed as well as an outlook is given.

Draft Genome Sequence of Riemerella anatipestifer Isolate 17CS0503.

Riemerella anatipestifer is a Gram-negative bacterium belonging to the family Flavobacteriaceae It is primarily associated with acute septicemia in younger birds. The R. anatipestifer isolate 17CS0503 described here was isolated from a Peking duck (Anas platyrhynchos domesticus) in Hannover, Germany, in 1999.

[Application of essential phospholipids in the treatment and prophylaxis of postcholecystectomy syndrome].

The experience of drug use in the clinic Enerliv (of "Berlin - Chemie Menarini" Germany) in 58 patients is the complex treatment of postcholecystectomy syndrome in generalised. The drug has hepatoprotective and cholesterol-lowering effect, effectively eliminates pain and dyspeptic symptoms, normalize biochemical parameters.

[Acute delusional psychosis and neuroleptic malignant syndrome after emigration of a Russian German patient].

Emigration is often followed by psychic disorders. The special issue of Germans from the GUS-States immigrating to Germany is presented. The modus of paranoid reaction is discussed along the biography and the criteria of ICD 10. The acute paranoid psychosis was complicated by a neuroleptic malignant syndrome.

[Cryptosporidia and other endoparasites in heifers imported into the Czech Republic].

Totally 887 heifers of Holstein-Friesian breed mostly in late pregnancy imported to the Czech Republic from France (597), Germany (89), Denmark (181) and Holland (20) were examined coprologically from September 1993 to March 1995 in the parasitological laboratory of the National Veterinary Institute (NVI). Prague. Feces were sampled individually, rectally, always on days 1-3 following importation from heifers housed in particular quarantine sheds. In compliance with presently valid veterinary regulations, all animals were examined for liver fluke disease (fascioliasis) and lungworm. Moreover, …

[Comparative Evaluation of a New-Generation HBsAg Assay versus a Conventional Method in Occult HBV Infection and Low-level HBsAg Positivity].

This study aimed to comparatively evaluate the conventional hepatitis B surface antigen (HBsAg) assay and the next-generation HBsAg NEXT (HBsAgNx) assay in samples with low-level HBsAg positivity and in cases of occult hepatitis B infection (OBI). A total of 497 individuals were included in the study, comprising 300 individuals with low-level HBsAg positivity, 100 OBI cases (64 seropositive and 36 seronegative) and 97 healthy controls. Serum samples were analyzed using the Abbott ARCHITECT HBsAg Qualitative II assay (Abbott Diagnostics, Wiesbaden, Germany) and the Abbott Alinity i HBsAg NEXT a…

The cost-effectiveness of predictive algorithm guided primary antidepressant treatment: economic evaluation of the multinational PReDicT randomised controlled trial.

BACKGROUND: The PReDicT study showed that predictive algorithm-guided antidepressant treatment reduces anxiety and improves functioning in patients with depression. AIMS: To estimate the costs, outcomes and cost-effectiveness of the PReDicT test compared with treatment as usual (TAU) for primary depression care in five European countries. METHOD: Within-trial economic analysis was conducted over 24 weeks from the health/social care and societal perspectives alongside the PReDicT trial (NCT02790970) in France, Germany, The Netherlands, Spain, and the UK, according to Consolidated Health Econo…

Feasibility of Integrating a Standardized Psychosocial Follow-Up After Childhood Cancer-An Interim Analysis of the LE-Na Study.

BACKGROUND: Many childhood and adolescent cancer survivors suffer from late effects that impair quality of life and life expectancy. However, only an estimated 5% of > 47,000 survivors in Germany receive adequate long-term follow-up (LTFU) care. The LE-Na (Evaluation and implementation of multidisciplinary, standardized, guideline-based long-term follow-up care for adult survivors of childhood cancer in Germany) study aims to address this care gap. Our interim analysis compares three recruitment and information pathways and provides information on the feasibility and acceptance of a guideline-…

A multiregional study of presentation and outcomes in upper tract urothelial cancer: Data from East Asia and Europe.

OBJECTIVE: Clinical features of upper tract urothelial carcinoma (UTUC) vary widely across countries. We aimed to provide clinical observations and compare oncological outcomes among regions in East Asia and Europe. METHODS: This retrospective study (March 2000 to July 2020) included 664 UTUC patients undergoing radical nephroureterectomy in China, Japan, the Republic of Korea, and Germany. Cohorts from China comprised patients from the Hong Kong Special Administrative Region and the Taiwan region, respectively. Demographic and clinicopathological parameters were analyzed. Continuous variable…

Geographical accessibility and case loads in subarachnoid hemorrhage care: a nationwide study of German hospitals.

This observational cross-sectional study aims to investigate the accessibility of German hospitals in the event of an aneurysmal subarachnoi … and accessibility metrics were sourced from the trinovis VISION platform (trinovis GmbH, Hannover, Germany) using the tools "hospitals" and "accessibility". A total of 7,855 SAH cases were treated in 794 hospitals across Germany. Among these, 27.3% of hospitals provided extended emergency care (treating 1,249 cases), and 19.6% offered comprehensive care …

Modelling years of life lost due to acute type A aortic dissection in the German healthcare setting: a predictive study.

OBJECTIVES: This study aimed to develop a patient-centred approach to the burden of acute type A aortic dissection (ATAAD) through modelling … he literature review. PARTICIPANTS: The study included a comprehensive modelling of ATAAD cases in Germany but did not directly involve participants. INTERVENTIONS: There were no specific interventions applied in this study based on the modelling design. PRIMARY AND SECONDARY OUTCOME MEASURES: The single outcome measure was the estimation of YLL due to …

Identifying intersectional groups at risk for missing breast cancer screening: Comparing regression- and decision tree-based approaches.

Malignant neoplasm of the breast was the fifth leading cause of death among women in Germany in 2020. To improve early detection, nationwide breast cancer screening (BCS) programmes for women 50-69 have been implemented since 2005. However, Germany has not reached the European benchmark of 70% participation, and socio-demographic inequalities persist. At the same time, challenges exist to identify groups of women at high risk for non-participation, since it is likely that this is due to disadvantages on multiple social dimensions. This study, therefore, aimed to identify intersectional groups …

Media coverage, fake news, and the diffusion of xenophobic violence: A fine-grained county-level analysis of the geographic and temporal patterns of arson attacks during the German refugee crisis 2015-2017.

Over the year of 2015, about 800.000 refugees arrived in Germany, a number which equals around one percent of the total population. This migration process was labelled the refugee crisis and was accompanied by a contested debate. On the one hand, there was a widespread willingness to voluntarily help arriving refugees, on the other hand, the number of xenophobic attacks against refugees drastically increased. Our paper will focus on a specific form of xenophobic violence with a strong symbolic meaning: We analyze how arson attacks against collective accommodation facilities spread. Using a com…

Epidemiology of hepatitis D virus infection in Europe: Is it vanishing?

Co-infection with hepatitis delta virus (HDV) is a challenging health care problem worldwide, estimated to occur in approximately 5%-10% of … ries. Anti-HDV prevalence is high in Greenland, Norway, Romania, Sweden and Italy. Belgium, France, Germany, Spain, Switzerland, Turkey and United Kingdom reported decreasing prevalences. Among cirrhotic HBV patients, Germany, Italy and Turkey reported higher rates of HDV. The studies including centres across the Europe reported that HIV-HBV coinfected in …

Extended-spectrum β-lactamase producing Enterobacteriaceae in bulk tank milk from German dairy farms.

Although the dairy farm environment is a known source of extended-spectrum β-lactamase (ESBL)-producing bacteria, surveillance data on ESBL in the milk production chain are still scarce. This study aimed at estimating the dimensions of the problem for public health and animal welfare by surveying ESBL-producing Enterobacteriaceae in raw bulk tank milk in Germany. Samples from 866 dairy farms, comprising about 1% of the total number of dairy farms in Germany, were first screened for presence of cefotaxime-resistant bacteria by selective enrichment. Suspect colonies were identified phenotypicall…

DNase SISPA-next generation sequencing confirms Schmallenberg virus in Belgian field samples and identifies genetic variation in Europe.

In 2011, a novel Orthobunyavirus was identified in cattle and sheep in Germany and The Netherlands. This virus was named Schmallenberg virus (SBV). Later, presence of the virus was confirmed using real time RT-PCR in cases of congenital malformations of bovines and ovines in several European countries, including Belgium. In the absence of specific sequencing protocols for this novel virus we confirmed its presence in RT-qPCR positive field samples using DNase SISPA-next generation sequencing (NGS), a virus discovery method based on random amplification and next generation sequencing. An in vit…

Long-term results of riboflavin ultraviolet a corneal collagen cross-linking for keratoconus in Italy: the Siena eye cross study.

PURPOSE: To report the long-term results of 44 keratoconic eyes treated by combined riboflavin ultraviolet A collagen cross-linking in the f … ount (I Konan, Non Con Robo; Konan Medical, Inc., Hyogo, Japan), optical (Visante OCT; Zeiss, Jena, Germany) and ultrasound (DGH; Pachette, Exton, Pennsylvania, USA) pachymetry, corneal topography and surface aberrometry (CSO EyeTop, Florence, Italy), tomography (Orbscan IIz; Bausch & Lomb Inc., Rochester, New York, USA), posterior segment optical coheren …

Susceptibility patterns of bacterial isolates from hospitalised patients with respiratory tract infections (MOXIAKTIV Study).

The objective of this study was to determine: (i) the prevalence of resistance in current clinical isolates of Streptococcus pneumoniae, Staphylococcus aureus, Haemophilus influenzae, Moraxella catarrhalis and Klebsiella pneumoniae; (ii) the prevalence of production of extended-spectrum beta-lactamases (ESBLs) and methicillin resistance in S. aureus; and (iii) regional differences in the prevalence of ESBL production and clonality of K. pneumoniae isolates. Pathogens causing respiratory tract infections in hospitalised patients were prospectively collected from all over Germany. Drugs tested b…

Tuberculosis contact investigation with a new, specific blood test in a low-incidence population containing a high proportion of BCG-vaccinated persons.

BACKGROUND: BCG-vaccination can confound tuberculin skin test (TST) reactions in the diagnosis of latent tuberculosis infection. METHODS: We compared the TST with a Mycobacterium tuberculosis specific whole blood interferon-gamma assay (QuantiFERON-TB-Gold In Tube; QFT-G) during ongoing investigations among close contacts of sputum smear positive source cases in Hamburg, Germany. RESULTS: During a 6-month period, 309 contacts (mean age 28.5 +/- 10.5 years) from a total of 15 source cases underwent both TST and QFT-G testing. Of those, 157 (50.8%) had received BCG vaccination and 84 (27.2%) h…