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Decreasing Pain Intensity in Adult Patients With Cancer Through Music Therapy: A Complementary Non-Pharmacological Approach.

BackgroundAdequate pain management continues to be an unmet need in patients with cancer. Pain is known to impact the quality of life. It is recommended that treatment plans include pharmacological and complementary non-pharmacological methods for managing pain. Music listening therapy is an evidence-based intervention used to manage acute and chronic pain in adult patients with cancer.MethodsThis evidence-based practice project applied the use of music therapy in adult patients with cancer experiencing moderate to severe pain despite current pharmacological treatment in a rural outpatient onc

Analysis of the Mortality Trends of 23 Major Cancers in the Indian Population Between 2000 and 2019: A Joinpoint Regression Analysis.

PurposeCancer mortality trends have not been documented across the population of India. We, therefore, analyzed the overall and individual cancer mortality trends for 23 major cancers between 2000 and 2019 on the basis of Global Health Observatory (GHO) database.Materials and methodsThis study examined cancer mortality trends for 23 major cancer sites on the basis of 12.85 million cancer deaths obtained from the GHO of the WHO between 2000 and 2019. A joinpoint regression model was used to analyze the long-term trends of cancer mortality. Annual percentage change (APC) and average APC were est

Individual Trade-Offs Between Possible Benefits and Risks of Cancer Treatments: Results from a Stated Preference Study with Patients with Multiple Myeloma.

BACKGROUND: The objectives of this study were to elicit the preferences of patients with multiple myeloma regarding the possible benefits and risks of cancer treatments and to illustrate how such data may be used to estimate patients' acceptance of new treatments. PATIENTS AND METHODS: Patients with multiple myeloma from the cancer charity Myeloma UK were invited to participate in an online survey based on multicriteria decision analysis and swing weighting to elicit individual stated preferences for the following attributes: (a) 1-year progression-free survival (PFS, ranging from 50% to 90%)

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… A limitation of this study is that we did not collect any information on level of education or psychosocial and cognitive factors, meaning that we were not able to further explore how the construction and elicitation of the preferences might have been affected by factors such as health literacy, numeracy …

Последствия программы, основанной на модели адаптации Роя, в отношении навыков обучения детей с множественным склерозом.

СПРАВОЧНАЯ ИНФОРМАЦИЯ: На здоровье детей влияет множественный склероз (МС) у их родителей и различные его осложнения. С учетом этого, это исследование было проведено с целью изучения воздействия программы, основанной на модели адаптации Роя, на способности детей пациентов с синдромом MS. МАТЕРИАЛЫ И МЕТОДЫ: 78 детей 78 Пациенты MS из Ассоциации поддержки MS в Шахрекорде, в том числе около 1800 пациенты 2018 с использованием квазиэкспериментального метода. Образцы были отобраны с помощью удобного метода отбора проб, и они заполнили контрольный перечень, подготовленный исследователями, на основе

Screening for comprehensive social needs in patients with cancer: a narrative review.

BackgroundPatients with cancer who report social needs have worse quality of life, lower health-care access, and suboptimal health outcomes. However, screening for social needs does not happen systematically, and successful screening tools, strategies, and workflows have seldom been described. The downstream effects of screening including resource navigation have also not been well characterized. The objective of this narrative review was to fill these gaps.MethodsTwo investigators searched PubMed and Embase for studies that implemented a patient-facing social screening tool among patients wit

Dengue virus infection in hematopoietic stem cell transplant recipients: A case series and comparative literature review from dengue endemic region.

This case series describes the wide spectrum of clinical presentation, laboratory findings, and morbidity/mortality associated with dengue fever in hematopoietic stem cell transplant recipients, treated in a dengue endemic region. The risk of acquiring viral infections increases manifold after transplant due to the severely immunocompromised state amid conditioning toxicity and immunosuppressive therapy. The classical warning signs of dengue viremia are often masked in posttransplant patients, leading to a missed diagnosis of dengue and grave consequences observed in some of the patients. Accu

Important learning points for setting up a dental-oncology service in Ireland.

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… Refugees often face worse oral health outcomes and are disabled by challenges such as health literacy, cultural differences, institutional discrimination, and lack of financial support. A growing additional facet of dental oncology is the care of the displaced cancer patient. …

Financial Toxicity in Patients With Breast Cancer Treated at Private Medicine Institutions in Brazil.

Financial toxicity (FT) refers to the negative impact of the financial burden of cancer diagnosis and treatment on patients' well-being. With rising global costs of oncologic therapies, diagnostics, and supportive care, FT has become a key concern in cancer care, influencing adherence, quality of life, and outcomes. Breast cancer, given its high prevalence and socioeconomic implications, is notably associated with FT. Beyond direct medical expenses, patients often face income loss and out-of-pocket costs for supportive care, which can significantly affect their therapeutic trajectory. Addressi

Culturally Tailored Home-based Yoga Intervention for Lymphoma Patients on Chemotherapy.

ContextAlthough proven effective in solid cancers, there is a dearth of evidence-based studies supporting yoga as an intervention to improve health-related quality of life (HRQOL) among patients with lymphoma.AimThe aim of this study was to develop a remotely supervised, home-based yoga intervention to improve HRQOL for lymphoma patients undergoing chemotherapy.SettingsThis project was conducted at a tertiary care hospital in Northern India.MethodologyExperts in lymphoma, yoga, psychiatry, and nursing collaborated to formulate the intervention. Following a comprehensive literature review and s

Evaluation of the SCA instrument for measuring patient satisfaction with cancer care administered via paper or via the Internet.

BackgroundPatients' perspectives provide valuable information on quality of care. This study evaluates the feasibility and validity of Internet administration of Service Satisfaction Scale for Cancer Care (SCA) to assess patient satisfaction with outcome, practitioner manner/skill, information, and waiting/access.Patients and methodsPrimary data collected from November 2007 to April 2008. Patients receiving cancer care within 1 year were recruited from oncology, surgery, and radiation clinics at a tertiary care hospital. An Internet-based version of the 16-item SCA was developed. Participants

Ожирение и риск эпидемических подстрекательских заболеваний: исследование реальных тенденций с использованием электронных медицинских записей.

Ожирение - это растущая глобальная проблема в области здравоохранения и хроническое подстрекательское состояние, которое может повлиять на иммунную терпимость и автоиммунитет. В то время как в предыдущих исследованиях рассматривались связи между ожирением и отдельными иммунизированными подстрекательскими заболеваниями (ИМИД), более широкое воздействие ожирения в широком спектре ИМИД остается неясным. Мы провели крупномасштабное когортное исследование с использованием глобальной электронной базы данных о состоянии здоровья населения TriNetX. Взрослые ≥ 18 годы с индексом массы тела (ИОВ) ≥ 18.5

Leveraging patient experience data to guide medicines development, regulation, access decisions and clinical care in the EU.

Patient experience data (PED), provided by patients/their carers without interpretation by clinicians, directly capture what matters more to patients on their medical condition, treatment and impact of healthcare. PED can be collected through different methodologies and these need to be robust and validated for its intended use. Medicine regulators are increasingly encouraging stakeholders to generate, collect and submit PED to support both scientific advice in development programs and regulatory decisions on the approval and use of these medicines. This article reviews the existing definition

Using digital technology to support wellbeing and independence among people living with incurable cancers: a systematic review.

PurposeThe purpose of this systematic review is to summarise and evaluate the feasibility, acceptability, and potential efficacy of using digital technology to deliver physical activity and/or nutrition interventions to promote wellbeing and independence among adults with advanced or incurable cancer.MethodsSystematic structured searches for any experimental study exploring physical activity and/or nutrition intervention delivery with digital technology were conducted in PsycINFO, MEDLINE, EMBASE, CINAHL, Web of Science Core Collection, and the Cochrane Central Register of Controlled Trials. A

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… Kemp E et al (2021) Health literacy, digital health literacy and the implementation of digital health technologies in cancer care: the need for a strategic approach. Health Promot J Austr 32(Suppl 1):104–114 20. …

Exploring the ethical decision-making experience of caregivers of end stage cancer patients in Iran: a phenomenological study.

BackgroundEthical decision making is a complex issue because it strongly depends on the religion, beliefs, traditional laws and moral views of each society. The purpose of this study was to explore the experience of Iranian family caregivers of end stage cancer patients about ethical decision making.MethodsThis qualitative study is based on van Manen's method of hermeneutic phenomenology. In-depth interviews were carried out to collect data. Participants were 12 caregiver. Audiotapes were transcribed and analyzed for common themes that represented the participants' experiences. Trustworthiness

Exploring Affordable Curative Therapy for Sickle Cell Disease in Africa: A Comprehensive Overview.

The practical aspects of developing curative treatments for sickle cell disease (SCD) in Africa, such as gene therapy and hematopoietic stem cell transplantation, involve strengthening healthcare infrastructure, training healthcare professionals, establishing regional treatment centers, and creating national SCD programs. The costs associated with gene therapy and stem cell transplants can be prohibitive, especially in low- and middle-income countries. Strategies to address affordability, including local manufacturing, government funding, and partnerships with global health agencies, are essen

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… Advocacy and Awareness The education and engagement of a global SCD community, which is geographically dispersed and may have varying levels of health literacy, will be additional considerations for achieving equity. …

Cross-sectional survey on cancer patients' concerns and consultation needs with pharmacists at the time of initial diagnosis.

BackgroundThe immediate post-diagnosis period is a critical phase for cancer patients, marked by significant informational and emotional distress. Although pharmacists are well-positioned to provide support during this time, limited research has investigated patients' specific concerns and consultation needs immediately after diagnosis, particularly in differentiating between hospital and community pharmacists. This study aimed to clarify cancer patients' concrete concerns and consultation preferences immediately following diagnosis, with a focus on the respective roles of hospital and communi

The Prevalence of Prostate Cancer Among Young Men Below 55 Years of Age in Nigeria.

IntroductionProstate cancer is the most common cancer in men. It was initially a disease of older men above the age of 55 years. Of recent, there has been reports of increase in the number of young men MethodsData on the prevalence of young men ResultsIn 4864 men diagnosed with malignancies before age 55, PCa was the second common, following liver cancer. Out of a total of 4091 cases of PCa in all age groups, 355 were diagnosed in men ConclusionsPCa is the second most common cancer in young Nigerian men aged< 55 years preceded by liver cancer. The proportion of young men with PCa was 8.86%. It

A Survey Study of Patient-Physician Communication and Treatment Decision-Making Preference at Treatment Initiation and After Disease Stabilization in Newly Diagnosed Multiple Myeloma.

INTRODUCTION: We present real-world evidence of patient-physician communication for patients with newly diagnosed multiple myeloma (NDMM) who have not received hematopoietic stem cell transplantation. METHODS: An observational survey study was conducted in Japan (September‒November 2024). Patients with NDMM completed a self-reported 34-item survey (online or paper-based), and hematologists treating patients with multiple myeloma completed a self-reported 18-item survey online. Communication status between patients and physicians and information on patients' treatment expectations, values, emo

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… Furthermore, patients were recruited from an advocacy group and had stable disease; therefore, they were more likely to be satisfied with their treatment and may have had higher health literacy than the general patient population. …

The patient, diagnostic, and treatment intervals in adult patients with cancer from high- and lower-income countries: A systematic review and meta-analysis.

BackgroundLonger time intervals to diagnosis and treatment are associated with worse survival for various types of cancer. The patient, diagnostic, and treatment intervals are considered core indicators for early diagnosis and treatment. This review estimated the median duration of these intervals for various types of cancer and compared it across high- and lower-income countries.Methods and findingsWe conducted a systematic review with meta-analysis (prospectively registered protocol CRD42020200752). Three databases (MEDLINE, Embase, and Web of Science) and information sources including grey

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… Common barriers to early diagnosis and care such as poor health literacy, cancer stigma, lack of access to diagnostic tests and treatment services, and financial, geographical, or logistical barriers are likely to be exacerbated in lower-income contexts, contributing to longer intervals on the cancer … However, there are unique factors in lower-income contexts such as low health literacy, the use of alternative medicine, female-specific barriers (e.g., the need for family permission to seek help), strong negative stigma of cancer treatment, and financial and access barriers that may delay help-seeking …

Artificial intelligence for risk assessment and outcome prediction in malignant haematology.

Risk stratification is the backbone of clinical decision-making for patients with haematological malignancies. Models currently used in routine clinical practice often rely on static rules, conventional statistics and expert consensus. While pragmatic and accessible, these models fail to capture the complex biological interactions and patient heterogeneity, especially as data dimensionality grows given the availability of more comprehensive molecular analysis. Artificial intelligence (AI), particularly machine learning (ML), offers the potential to process such high-dimensional data, uncover l