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Первый триместрный разрыв беременности, связанный с вирусом варицелла: гистологическое определение случая.

Сообщается о патологической демонстрации инфекции варицелы в первой триместре поврежденной ткани. 24-летняя приригавида заразилась ветрянкой примерно через 38 дней после последнего менструального периода или в возрасте 24 дней от эмбриона. Концепция пережила еще от 4 до 5 недель. Покрашенный эмбрион и плацентальная ткань выявили ядерные изменения, согласующиеся с инфекцией варицелы. Иммуногистохимические пятна и электронная микроскопия были подтверждены.

Совпадение в аннотации оригинала
Pathological demonstration of varicella infection in first trimester aborted tissue is reported. A 24-year-old primigravida manifested chickenpox infection about 38 days after her last menstrual period or at 24 days age of the embryo. The conceptus survived another 4 to 5 weeks. The macerated embryo and placental tissue revealed nuclear changes consistent wi…

Managing varicella zoster virus contact and infection in patients on anti-rheumatic therapy.

Chickenpox and shingles can be more severe and occasionally life threatening in immunosuppressed patients. As such, some groups warrant a more detailed history, serological testing and consideration of prophylaxis following contact with the virus. Active disease may also require more aggressive treatment with antivirals. Guidance for the use of varicella zoster immunoglobulin has recently been updated by Public Health England with important implications for rheumatology patients.

Not every skin rash in a returning adult male traveler is monkeypox.

In May 2022, several European countries including Spain reported cluster of monkeypox cases with no apparent travel to endemic areas. We report a suspected case of monkeypox in Saudi Arabia in a healthy 30-year-old man who returned from Spain and the Netherlands with fever and rash for six days duration during the same time period of the outbreak, he was suspected to have monkeypox but was ultimately diagnosed with chickenpox.

Legionnaires' disease contracted from patient workplace: First report of a severe case of coinfection with varicella-zoster virus.

A middle-aged immunocompetent woman was diagnosed and treated for a severe pulmonary human herpesvirus 3 infection. During the treatment, an infection from Legionella pneumophila serogroup 1 was also diagnosed. This coinfection threatened the life of the patient and led to serious permanent sequelae. This report highlights the importance of preventing Legionella environmental contamination, suspecting Legionella coinfection in patients with viral pneumonia, and vaccinating susceptible adults against chickenpox.

Recombinant varicella-zoster virus vaccines as platforms for expression of foreign antigens.

Varicella-zoster virus (VZV) vaccines induce immunity against childhood chickenpox and against shingles in older adults. The safety, efficacy, and widespread use of VZV vaccines suggest that they may also be effective as recombinant vaccines against other infectious diseases that affect the young and the elderly. The generation of recombinant VZV vaccines and their evaluation in animal models are reviewed. The potential advantages and limitations of recombinant VZV vaccines are addressed.

Overview: the biology of varicella-zoster virus infection.

Varicella-zoster virus infection is manifested initially as chickenpox. The virus persists for life in sensory nerve ganglia, from which it reactivates in many people to cause zoster. Among the many recognized complications of these infections, post-zoster neuralgia is the most frequently debilitating. The molecular events of virus replication, latency, and reactivation, and the pathogenesis of post-zoster neuralgia, are incompletely understood and inadequately addressed by current therapeutic strategies.

Different Clinical Presentations and Outcomes of Disseminated Varicella in Children With Primary and Acquired Immunodeficiencies.

Primary infection with varicella-zoster virus (VZV) causes chickenpox, a benign and self-limited disease in healthy children. In patients with primary or acquired immunodeficiencies, primary infection can be life-threatening, due to rapid dissemination of the virus to various organs [lung, gastrointestinal tract, liver, eye, central nervous system (CNS)]. We retrospectively described and compared the clinical presentations and outcomes of disseminated varicella infection (DV) in patients with acquired (AID) (n= 7) and primary (PID) (n= 12) immunodeficiencies. Patients with AID were on immunosu…

Economic burden of varicella complications in two referral centers in Mexico.

Varicella-zoster virus causes varicella (chicken-pox), mainly in young children. Most cases are mild but serious complications can occur, resulting in significant morbidity and mortality. The objective of this study was to estimate the cost burden of varicella hospitalizations in two pediatric reference hospitals in Mexico. This retrospective observational study collected data on patients aged <18 years admitted to two third-level referral hospitals in Mexico. Cases were identified from hospital records using International Classification of Diseases Ninth Revision (ICD-9) codes 052 Chickenpox,…

Advances in the treatment of varicella-zoster virus infections.

Varicella-zoster virus (VZV) causes two distinct diseases, varicella (chickenpox) and shingles (herpes zoster). Chickenpox occurs subsequent to primary infection, while herpes zoster (usually associated with aging and immunosuppression) appears as a consequence of reactivation of latent virus. The major complication of shingles is postherpetic neuralgia. Vaccination strategies to prevent varicella or shingles and the current status of antivirals against VZV will be discussed in this chapter. Varivax®, a live-attenuated vaccine, is available for pediatric varicella. Zostavax® is used to boost V…

[Viral patology and oral manifestation].

UNLABELLED: Although the medical and biological importance of ringworm infections was acknowledged a long time ago, the putting-up-to-date o … ). The oral manifestations were mainly located at the level of the palatine and velopalatine vault. Chickenpox was diagnosed within the age interval 7 days-52 years (median-8 years). The chickenpox enantem was observed in 90.42% of the cases, being represented by varix wounds, or "hemorrhagic spots", mostly located at the level of the fibrous mucose membrane …

Герпес зостер офтальмикс в здоровом 7-летнем ребенке.

В противном случае здоровый ребенок в возрасте 07 лет, не привитый к ветрянке по оксе и имеющий историю заражения ветряной поксией в возрасте 02 лет с красными повреждениями в правой верхней крышке, правой стороне лобка, вершине и правой стороне носа и дефектным зрением в правом глазу в больнице Медицинского колледжа Мименсинга, через 20 дней после появления волдыря в том же районе. При осмотре на той же местности были обнаружены гранулирующие ткани. Там не было волос и кожи. Лизия была строго ограничена правой стороной средней линии. Отсутствовали ресницы с правой верхней крышкой, и было непр

Совпадение в аннотации оригинала
A 07 years otherwise healthy child, non vaccinated for chickenpox and with a history of chickenpox infection at 02 years of age presented with red colored lesions in right upper lid, right side of forehead, vertex and right side of nose and defective vision in right eye in Mymensingh Medical College Hospital, 20 days after the appearance of blister in the sa…

Luminometric microplate hybridization for detection of varicella-zoster virus PCR product from cerebrospinal fluid.

We modified and optimized a new microplate hybridization assay to detect the varciella-zoster virus (VZV) PCR product, and studied cerebrosp … plified DNA. All 25 CSF samples were also positive in Southern blotting. Among the patients, 10 had chickenpox, 4 had shingles, and 11 had no rash at all. The detection rate of VZV-specific DNA by microplate hybridization was 30% higher than that obtained by conventional agarose gel electrophoresis. In most patients the diagnosis was confirmed by demonstrati …

Latent varicella-zoster viral DNA in human trigeminal and thoracic ganglia.

BACKGROUND: Some human herpesviruses become latent in dorsal-root ganglia. Primary infection with the varicella-zoster virus causes chickenpox, followed by latency, and subsequent reactivation leading to shingles (zoster), but the frequency and distribution of latent virus have not been established. METHODS: Using the polymerase chain reaction, we performed postmortem examinations of trigeminal and thoracic ganglia of 23 subjects 33 to 88 years old who had not recently had chickenpox or shingles to identify the presence of latent varicella-zoster viral DNA. Oligonucleotide primers representin…

[A 19-year-old male migrant with urethritis and vesicular rash].

We report the case of a 19-year-old Malian patient, who presented with urethritis and a vesicular rash during the summer of 2022, following a probable heterosexual intercourse. The epidemic context among the male homosexual population and the clinical picture without genital lesions or lymphadenopathy allowed us to discuss both chickenpox and mpox, the latter being finally confirmed by the detection of Monkeypox virus DNA from vesicular fluid.

A Pediatric Case of Stevens-Johnson Syndrome With Extensive Palmoplantar Involvement Following Varicella Infection.

Stevens-Johnson syndrome (SJS) is a rare but dangerous clinical condition characterized by extensive skin lesions and erosive mucosal lesions. SJS is typically caused by an allergic reaction to a medicine, and occasionally, infectious causes can provoke the syndrome. The illness is considered a medical emergency, and treatment varies based on symptoms, with a focus on lesion treatment, airway and hemodynamic stability, and opportunistic infection avoidance. We report a case of 10 years old female patient who presented with chickenpox accompanied by high-grade fever. Ibuprofen was used to relie…

Intracranial hemorrhagic vasculitis in a child with varicella zoster virus infection: a case report.

BACKGROUND: Varicella zoster virus (VZV) infection is a common viral illness in children, typically manifesting as chickenpox and having a benign, self-limiting course. However, severe neurological complications-such as vasculitis resulting in intracranial hemorrhage-although rare, can occur and are associated with significant morbidity and mortality. CASE PRESENTATION: We present the case of a previously healthy 7-year-old boy who developed intracranial hemorrhagic vasculitis 14 days after a primary VZV infection. The child experienced sudden-onset seizures and altered sensorium. Neuroimagin…

Identification of novel potential inhibitors of varicella-zoster virus thymidine kinase from ethnopharmacologic relevant plants through an in-silico approach.

Although Varicella or chickenpox infection which is caused by the varicella-zoster virus (VZV) has significantly been managed through vaccination, it remains an infection that poses threats to the nearest future due to therapeutic drawbacks. The focus of this research was geared towards in silico screening for the identification of novel compounds in plants of ethnopharmacological relevance in the treatment of chicken pox in West Africa. The work evaluated 65 compounds reported to be present in Achillea millefolium, Psidium guajava and Vitex doniana sweet to identify potential inhibitors of th…

Varicella-zoster virus cns disease clinical features in ukrainian patients. prospective study.

OBJECTIVE: Introduction: Herpes zoster (HZ), or shingles, is localized disease characterized by unilateral radicular pain and a vesicular rash limited to the area of skin innervated by a single dorsal root or cranial sensory ganglion. Whereas varicella, or chickenpox, results from primary exogenous varicella-zoster virus (VZV) infection, HZ is caused by reactivation of endogenous VZV that has persisted in latent form within sensory ganglia following an earlier episode of chickenpox. The aim: To explore the clinical features, diagnosis, and treatment of CNS injury caused by VZV infection in a p…

Application of Oral Fluid Assays in Support of Mumps, Rubella and Varicella Control Programs.

Detection of specific viral antibody or nucleic acid produced by infection or immunization, using oral fluid samples, offers increased poten … r case confirmation. Universal varicella immunization of children has led to a drastic reduction of chickenpox in those countries where it is used; however, in England and Wales such a policy has not been instigated. Consequently, in England and Wales most children have had chickenpox by age 10 years; however, small, but significant, numbers of adults remain …

Putative factors associated with molar incisor hypomineralisation: an epidemiological study.

AIM: The aim of the study was to examine the aetiological factors involved in the development of molar incisor hypomineralisation (MIH). ME … astrointestinal problems (3.9 %), pneumonia (6.3 %), frequent fever (26.1 %), measles (14.7 %), and chickenpox (29.3 %) before age 4 years. STATISTICS: Prevalence did not vary significantly between girls and boys (p > 0.05). Prematurity, gastrointestinal problems, pneumonia, frequent high fever, measles, and chickenpox before age 4 years were found to be si …