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AMCD: A multi-domain agricultural crop and flower image dataset for deep learning-based classification.

The Agricultural Multidisciplinary Collection Dataset (AMCD) contains 5405 JPG images of agricultural crops and flowers collected in Bangladesh. The images are organized into four domains: fruits, vegetables, flowers, and crops/grains. These domains contain 77 subclasses representing commonly observed agricultural and floricultural specimens. Images were captured manually using smartphone cameras at farms, marketplaces, and gardens in Savar, Dhamrai, and Manikganj in the Dhaka Division of Bangladesh between 27 January 2025 and 20 May 2025. The data include natural outdoor lighting, variable ba…

Biosensors with enzymatic amplification strategies for the detection of foodborne pathogenic microorganisms.

Foodborne pathogenic microorganisms pose serious threats to public health, underscoring the critical need for rapid detection methods. Biosensors serve as promising alternatives by integrating biorecognition elements with signal transduction systems, enabling efficient and specific detection of such pathogens. This review systematically summarizes the recent advances in biosensors for the detection of common foodborne pathogenic microorganisms across diverse food matrices, including poultry, vegetables, dairy products, aquatic products, etc., with focus on signal amplification strategies rangi…

Tissue-specific and environmental regulation of ascorbate accumulation in the cactus Nopalea cochenillifera.

Cacti are xerophytic plants characterized by water-storing cladodes, thick cuticles, and CAM photosynthesis, enabling high productivity under harsh conditions. They accumulate ascorbate (AsA) at levels comparable to those of leafy vegetables, potentially contributing to stress tolerance and nutritional value. However, the regulation of AsA accumulation in cacti remains poorly understood. Here, we used the dwarf prickly pear cactus Nopalea cochenillifera to investigate the tissue-specific distribution and environmental responses of AsA. AsA preferentially accumulated in the cortex, exhibited li…

High-molecular-weight fibroin as a preservation coating for perishable fruits.

Fresh fruits and vegetables are prone to spoilage during storage. To prolong the shelf life of perishable produce, various preservation technologies, such as plastic packaging, are widely used; however, many contribute to environmental pollution and food safety concerns. This study developed a simple and scalable coating solution based on high-molecular-weight (MW) fibroin for preserving fresh fruits. Specifically, the lightly-degraded silk protein was blended with edible alcohol to prepare the preservation coating solution. The incorporation of a moderate ethanol concentration (15%) not only …

Isothiocyanates as Ferroptosis Inducers to Promote Cancer Cell Death.

Cancer remains a leading cause of global mortality, with the therapeutic efficacy of anticancer drugs often hampered by late diagnosis and the development of chemotherapy resistance. Ferroptosis is an iron-dependent form of regulated non-apoptotic cell death driven by lipid peroxidation. It has emerged as a potential therapeutic target to overcome drug resistance in cancer. Isothiocyanates (ITCs) from cruciferous vegetables have garnered attention for their multi-target anticancer properties. In this review, we present the key mechanisms of ferroptosis and critically evaluate current evidence …

Development of a surface-enhanced Raman scattering-based immunochromatographic assay for sensitive detection of carbaryl residues.

In this study, novel tungsten disulfide (WS2)-gold composite core-shell (WS2@Au) nanoparticles were used to label carbaryl antibodies and Ra … hout any cross-reaction observed in other pesticides. Recoveries of carbaryl from spiked fruits and vegetables were 89% to 112%, with the coefficient of variation less than 7%. The established SERS-ICA method provides a rapid, ultrasensitive, and reliable strategy for on-site screening and quantitative analysis of carbaryl residues in complex food matrices, …

Kaempferol Counteracts Obesity and Impairs Adipogenesis by Suppressing PI3K/AKT/GSK3β-Mediated Mitotic Clonal Expansion and Attenuating Adipose Tissue Fibrosis.

Kaempferol, a widely present dietary flavonoid in numerous fruits and vegetables, possesses antiobesity potential with unclearly defined mechanisms. This study investigated how kaempferol regulates adipogenesis in 3T3-L1 preadipocytes and exerts antiobesity effects in high-fat diet (HFD)-induced obese mice. Kaempferol inhibited preadipocyte differentiation at the early mitotic clonal expansion (MCE) stage by S-phase (18 h) and G2/M-phase (24 h) cell cycle arrest. Mechanistically, this action was mediated through inhibition of the PI3K/AKT/GSK3β pathway. Application of the AKT activator SC79 co…

Targeting signaling pathways in neurodegenerative diseases: Quercetin's cellular and molecular mechanisms for neuroprotection.

BACKGROUND: Neurodegenerative diseases (NDs), including Alzheimer's disease, Parkinson's disease, and Huntington's disease, are complex and … e cellular and molecular pathways involved in neurodegeneration. Quercetin, a flavonoid abundant in vegetables and fruits, is gaining attention for its antioxidant, anti-inflammatory, and antiapoptotic properties. It regulates signaling pathways such as nuclear factor-κB (NF-κB), sirtuins, and phosphatidylinositol 3-kinase/protein kinase B (PI3K/Akt). These …

Dietary Patterns and Migraine: Insights and Impact.

Migraine is a prevalent neurological disorder characterized by significant disability and triggered by various factors, including dietary ha … d severity. Observational studies also indicate that maintaining a healthy diet, rich in fruits and vegetables and low in processed foods, is associated with better migraine outcomes. The effectiveness of these interventions varies among individuals, underscoring the importance of personalized approaches. Future studies should further explore the role of die …

Effects and Mechanisms of Dietary Natural Products on Ischemic Stroke: An Updated Review.

Ischemic stroke ranks among the primary contributors to mortality and prolonged disability globally, representing a significant public health challenge. Some clinical drugs for the treatment of ischemic stroke have significant side effects. Therefore, exploring effective therapeutic strategies is crucial. Some dietary natural products, such as fruits, vegetables, teas, herbs, nuts, probiotics and prebiotics, exert potential neuroprotective effects on ischemic stroke. The underlying mechanisms of action include suppressing oxidative stress, inhibiting inflammation, alleviating excitotoxicity, p…

Electrospun wheat gluten/zein nanofibers co-loaded with ferulic acid and TiO2 as potential food active packaging.

Globally, about one-third of fruits and vegetables are wasted each year due to spoilage, with foodborne microbial contamination and ethylene attack being the main causes. Traditional petroleum-based preservation materials have poor antimicrobial effects, low ethylene scavenging rate, causing serious pollution to the environment. Therefore, we developed a green packaging material based on plant-based protein wheat gluten (WG)/zein nanofiber films (NFs) loaded with ferulic acid (FA) and TiO2 nanoparticles (NPs) for antimicrobial and ethylene scavenging by electrospinning technology. The electros…

Herbal terpenoids activate autophagy and mitophagy through modulation of bioenergetics and protect from metabolic stress, sarcopenia and epigenetic aging.

Small molecular food components contribute to the health benefits of diets rich in fruits, vegetables, herbs and spices. The cellular mechanisms by which noncaloric bioactives promote healthspan are not well understood, limiting their use in disease prevention. Here, we deploy a whole-organism, high-content screen in zebrafish to profile food-derived compounds for activation of autophagy, a cellular quality control mechanism that promotes healthy aging. We identify thymol and carvacrol as activators of autophagy and mitophagy through a transient dampening of the mitochondrial membrane potentia…

Role of oral and gut microbiomes in enterosalivary nitrate metabolism and their effects on systemic disease.

Nitrate, which maintains hemostasis in systemic circulation, is obtained from nitrate-rich vegetables, concentrated, reabsorbed by the salivary glands, and reduced to nitrite and nitric oxide (NO•). The bioavailability of nitrate and nitrite depends on unique nitrate reductases present in specific bacterial communities in the mouth and gut of mammals. The dominant bacteria in the oral cavity, stomach, and gut differ among internal environments. Nitrate can modulate microbiota metabolism and has important pathophysiological functions in diseases such as cardiovascular diseases, gastrointestinal…

Hidradenitis suppurativa and daily lifestyle.

Hidradenitis suppurativa (HS) is a chronic, relapsing inflammatory skin disorder that significantly impairs quality of life. While its patho … ncing antimicrobial responses, and promoting the growth of beneficial gut microbiota. Diets rich in vegetables, fruits, chicken, and fish are supportive in maintaining immune balance. Conversely, detrimental factors, including smoking, alcohol consumption, obesity, and sleep disorders, are associated with heightened inflammatory responses, increased disease …

Морин гидрат: всеобъемлющий обзор терапевтического потенциала лечения неврологических заболеваний.

Фон: Морин гидрат представляет собой полифеноловый флавоноид, присутствующий в различных видах овощей, фруктов, орехов и морских продуктов. Согласно сообщениям, этот обзор позволяет выявить молекулярные механизмы и терапевтический потенциал Морина в связи с неврологическими заболеваниями, включая болезнь Паркинсона, болезнь Альцгеймера, травматическое повреждение мозга, нейропатическую боль, инсульт, болезнь Хантингтона, множественный склероз, амиотропический боковой склероз, депрессия, беспокойство, сон, энцефалопатию, шизофрению и психоз и т.д. энзиматическое ингибирование. Вывод: Несмотря н

Совпадение в аннотации оригинала
Background: Morin hydrate is a polyphenolic flavonoid present in various vegetables, fruits, nuts, and sea products. It has been reported to offer multiple protective effects against a range of diseases, including cancer, cardiovascular, liver, neurological, metabolic, and renal disorders.Objective: This review highlights the molecular mechanisms and therape…

Decreased mitochondrial translation confers 3,3'-Diindolylmethane resistance to Schizosaccharomyces pombe.

3,3'-Diindolylmethane (DIM), a compound derived from natural fruits and vegetables, is widely recognized for its anti-cancer activity. However, its action mechanisms remain ambiguous. In this study, to study the molecular mechanism of 3,3'-Diindolylmethane, we identified a novel mutation in the gene of mitochondrial translation elongation factor EF-Ts (tsf1+), a key factor in mitochondrial protein translation, that conferred DIM resistance to Schizosaccharomyces pombe. The tsf1Δ also conferred DIM resistance. Decreased mitochondrial translation was found to be responsible for conferring DIM re…

Sirtuin 1 serum concentration in healthy children - dependence on sex, age, stage of puberty, body weight and diet.

INTRODUCTION: Sirtuin 1 (SIRT1) is known to be involved in sensing cellular energy levels and regulating energy metabolism. This study aimed … ct to sex, age, height, weight and puberty. Whereas, it appeared that a higher frequency of fruits, vegetables and dairy products consumption was associated with an increase in serum SIRT1 levels. DISCUSSION: Studying SIRT1 in the context of children's health may have implications for a broader understanding of growth processes, pubertal development, metabo …

Heating conversion of indole-3-carbinol into N-substituted oligomers with anti-melanoma effect.

Cruciferous vegetables (CVs) are globally consumed with some health benefits believed to arise from indole-3-carbinol (I3C), a labile phytochemical liberated from indole glucosinolates, but few reports describe the effect of cooking on I3C reactions. Here, we present heat-promoted direct conversions of I3C in broccoli florets into indole derivatives, which are unique in the N-indolylmethylation and -hydroxymethylation of indole nuclei by 3-methyleneindole and formaldehyde formed in situ from the I3C dehydration and the dimerization of I3C to 3,3'-diindolylmethane (DIM), respectively. Such N-su…

Healthy eating among people on opioid agonist therapy: a qualitative study of patients' experiences and perspectives.

People with substance use disorders often have unhealthy diets, high in sweets and processed foods but low in nutritious items like fruits and vegetables, increasing noncommunicable disease risks. This study investigates healthy eating perceptions and barriers among individuals with opioid use disorder undergoing opioid agonist therapy. Interviews with 14 participants at opioid agonist therapy clinics in Western Norway, using a semi-structured guide and systematic text condensation for analysis, reveal that most participants view their diet as inadequate and express a desire to improve for bet…

A Rare Case of Superior Mesenteric Artery Thrombosis With Gangrenous Bowel in a Patient With Mitral Valve Replacement in a Hypocoagulable State.

Acute thromboembolism of the superior mesenteric artery (SMA) causing mesenteric ischemia has a grave prognosis with high mortality rates. I … ed ratio (INR) is essential for those on warfarin, as drugs and dietary changes (eating green leafy vegetables) can significantly affect INR levels. Early suspicion and prompt treatment are vital for improving outcomes.