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Understanding the cost of caring in medicine through personhood: A systematic scoping review of compassion fatigue, vicarious trauma and secondary traumatic stress.

BACKGROUND: Supporting seriously ill patients and their families through the illness trajectory renders physicians susceptible to compassion fatigue (CF). Traditionally characterized as emotional and physical exhaustion following sustained empathic engagement, emerging research suggests that CF involves deeper disruptions to belief systems and professional identity formation (PIF), alongside an interplay with other trauma-related strain including secondary traumatic stress (STS) and vicarious trauma (VT) within the broader 'cost of caring' framework. However, such conceptual understanding rema…

Effect of the Multicomponent Exercise Program MoveUS on the Kinematic Fatigue of People With Glenohumeral Instability: A Secondary Analysis From a Randomized Controlled Trial.

BACKGROUND AND PURPOSE: Kinematic movement analysis is highly relevant in patients with glenohumeral instability, a pathology characterized by fatigue-induced slowing of repetitive movements. However, the optimal exercise approach for this symptom remains unclear. This study aimed to determine the effect of the MoveUS Program on the improvement of kinematic fatigue in patients with glenohumeral instability. METHODS: This randomized controlled trial was developed at Axarquia Hospital (Spain). The study evaluated 47 adult patients with glenohumeral instability, and 38 patients finished the stud…

'It helps me stay on track': patient experiences using a mobile app for self-management of systemic sclerosis with a focus on fatigue in women.

OBJECTIVES: Fatigue is common and burdensome in people with systemic sclerosis (SSc), significantly impacting daily functioning and quality of life. Yet, it remains inadequately addressed in clinical care. This study aimed to explore participants' experiences using the RENEW (Resilience-building Energy Management to Enhance Well-being) mobile app as a standalone self-paced intervention without peer coaching for fatigue self-management. METHODS: Semi-structured interviews were conducted with participants with SSc following completion of the 12-week RENEW mobile app intervention. Interviews wer…

Impact of fatigue on activities of daily living in patients with rheumatoid arthritis: A cross-sectional study from the Aseer region, Saudi Arabia.

Fatigue is a prevalent and disabling feature of rheumatoid arthritis (RA) that interferes with everyday tasks and overall quality of life. Evidence on how RA-related fatigue affects activities of daily living (ADL) in Middle Eastern, and particularly Saudi Arabian, populations is sparse. This study aimed to quantify fatigue severity in patients with RA seen at a tertiary center in the Aseer region and examine its relationship with disease activity and ADL, using the Bristol RA Fatigue Multidimensional Questionnaire (BRAF-MDQ). We carried out a single-center, cross-sectional study with prospect…

The effect of fatigue on peak strain of hamstring muscles in dominant and non-dominant sides during sprinting: a pre-post intervention study.

BACKGROUND: Although fatigue is widely recognized as a risk factor for hamstring strain injuries, the mechanisms by which fatigue influences these injuries remain unclear. It is also uncertain whether fatigue differentially affects the risk factors for hamstring strain between lower limbs. METHODS: Nineteen male track-and-field athletes underwent a fatigue intervention, with optimal muscle length assessed pre- and post-fatigue. Key biomechanical parameters during sprinting were also analyzed before and after fatigue. RESULTS: Post-fatigue, the non-dominant limb showed significant reductions in…

Effectiveness of I-Exercises: A Comprehensive Ocular Exercise Protocol for Reducing Ocular Fatigue Among Students With Myopia in a Randomized Controlled Trial.

Background The prevalence of ocular fatigue associated with prolonged digital device use and sustained near-vision tasks is increasing among students with myopia. However, evidence regarding the effectiveness of structured ocular exercise programs remains limited. Objective To determine the effectiveness of a Comprehensive Ocular Exercise Module (I-Exercises) in reducing ocular fatigue symptoms among students with myopia. Methods A randomized controlled trial was conducted among 40 participants aged 18-25 years with myopia. Participants were randomly allocated using a computer-generated sequen…

Association of mRNA SARS-CoV-2 vaccination with fatigue and functional recovery in patients with post-acute sequelae of COVID-19 (PASC).

BACKGROUND: Patients with post-acute sequelae of SARS-CoV-2 (PASC) fear SARS-CoV-2 vaccine-linked symptom aggravation. Data on objective functional outcomes are limited. METHODS: We performed a retrospective analysis of an observational cohort at a post-COVID outpatient clinic at Hannover Medical School with standardized assessments at baseline and follow-up visit (3-6 months) in adults with confirmed SARS-CoV-2 infection and PASC. Participants were classified as vaccination (receipt of an additional SARS-CoV-2 vaccine dose between visits) or no vaccination. Primary outcomes were fatigue (Fat…

Total blood volume and red blood cell volume are not associated with orthostatic intolerance in adults with myalgic encephalomyelitis/chronic fatigue syndrome.

Orthostatic intolerance is common in myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and may worsen daily functioning. Although hypovolemia has been proposed as a contributor, its relationship to objective orthostatic abnormalities remains uncertain. We examined whether measured blood-volume abnormalities were associated with standardized lean-test outcomes. Adults meeting the 1994 ME/CFS criteria and reporting substantial post-exertional malaise underwent a 10-min lean test with capnography, followed 8 days later by total blood volume (TBV) measurement using the Daxor BVA-100. Sup…

Impact of Fatigue on Patient-Reported Outcomes and Work Productivity in Chronic Hepatitis B and C: Insights From a Multinational Registry Study.

Fatigue in chronic viral hepatitis may be associated with decreased health-related quality of life and other patient-reported outcomes (PROs). We evaluated the relationship between fatigue and PROs in patients with chronic hepatitis B (CHB) and chronic hepatitis C (CHC). Patients with CHB and CHC enrolled in the Global Liver Registry completed PRO instruments: FACIT-F, CLDQ (for CHB), CLDQ-HCV (for CHC), and WPAI:SHP. Fatigue was defined as FACIT-F Fatigue Scale (FS) score < 30 (scale range: 0-52). Among 2888 patients from 14 countries, 1561 had CHB (mean age 47 ± 13 years; 60% male; 13% advan…

The correlation between serum markers of oxidative stress and fatigue and related factors in minimally disabled patients with relapsing-remitting multiple sclerosis.

Oxidative stress is recognized as a key pathological mechanism in multiple sclerosis (MS), and fatigue is one of the most prevalent and disabling symptoms. In this cross-sectional study, 85 patients diagnosed with relapsing-remitting MS (RRMS) and Expanded Disability Status Scale (EDSS) < 4.5 were recruited. Fatigue was evaluated by the Comprehensive Fatigue Assessment battery MS (CFAB-MS), which also assesses fatigue-related factors. Venous blood samples were collected to measure levels of glutathione peroxidase (GPX), catalase (CAT), malondialdehyde (MDA), reduced glutathione (GSH), total an…

Надежность нейрофизиологических мер в верхних и нижних скелетных мышцах людей, страдающих высокой и низкой степенью множественной склерозной усталости.

В ходе этого исследования была изучена надежность результатов тест-испытания широкого диапазона нейрофизиологических мер, связанных с экстенсивностью колена (KE) и флексорой запястья (FF), у людей с множественным склерозом (PwMS) и совпадающими с системами контроля за здоровым здоровьем, до и после субмаксимальных периодических упражнений до отказа в работе. PwMS дихотомизировался в зависимости от того, испытывают ли они высокий (MS-HF) или низкий (MS-LF) уровень предполагаемой усталости MS на исходном уровне с использованием предельных значений шкалы усталости (FSS) (MS-HF ≥5; MS-LF <4). Сред

Совпадение в аннотации оригинала
This study investigated the test-retest reliability of a broad range of knee extensor (KE) and wrist flexor (WF) neurophysiological measures … ised according to whether they were experiencing high (MS-HF) or low (MS-LF) levels of perceived MS fatigue at baseline using the Fatigue Severity Scale (FSS) cut-points (MS-HF ≥5; MS-LF <4). Average (SD) FSS scores were 6.0 (0.6) vs 3.5 (1.1), respectively (p<0.001). With the caveat of wide 95% confidence intervals for some measures, intraclass correlati …

Influence of a diaphragmatic fatigue protocol in healthy male population on muscle strength, respiratory function and exercise capacity: A randomized clinical trial.

BACKGROUND: Inspiratory muscle fatigue has been shown to impair physical performance. This study investigated the impact of a specific inspiratory muscle fatigue protocol on lower limb muscle strength and cardiorespiratory outcomes in a cohort of physically active individuals. METHOD: A randomized controlled trial, adhering to CONSORT guidelines to ensure methodological rigor. Healthy male participants were randomly assigned to an inspiratory muscle fatigue group (EG) or control load group (CG). The EG performed a diaphragmatic fatigue protocol involving inspiratory exercises at 60 % of their…

Cognitive Complaints in Patients with Suspected Obstructive Sleep Apnea Are Associated with Sleepiness, Fatigue, and Anxiety, Not with Final Diagnosis or Objective Cognitive Impairment.

This study examined the nature, severity, and predictors of cognitive complaints in patients referred for suspected obstructive sleep apnea … nalyses examined predictors of cognitive complaints including AHI, sleepiness, anxiety, depression, fatigue, and neuropsychological performance. Compared to HCs, those with mild OSA reported more forgetfulness, distractibility, and working memory issues, while those with severe OSA reported more difficulties with initiative, both with large effect sizes. …

Muscle coactivation during knee joint-position sense assessments: the effect of muscle fatigue and implications for the magnitude of errors and directional bias.

PURPOSE: This study aimed to describe muscle coactivation during knee joint-position sense (KJPS) assessments in healthy individuals, before and after muscle fatigue, and to analyse the implications for the magnitude of errors and directional bias. METHODS: The KJPS of 21 healthy males was assessed in the sitting position through concentric (SIT_CC) and eccentric repositionings (SIT_ECC) to 45° of knee flexion. Two fatigue protocols were tested, consisting of concentric contractions of the knee extensors or flexors. Muscle coactivation indices were calculated based on the normalized mean acti…

Effects of Aerobic Exercises Combined With Music Therapy on Fatigue and Quality of Life in Females With Thyroidectomy Following Thyroid Cancer: An Experimental Study.

Background Thyroid cancer is a type of cancer that starts in the thyroid gland. Thyroid cancer is characterized by the abnormal and uncontro … nd receive insufficient levothyroxine supplementation are more prone to experience problems such as fatigue, which can significantly affect their quality of life (QoL). Fatigue is a prevalent and discomforting symptom among oncology patients, though its prevalence can vary depending on cancer type, stage, and treatment. Exercise is becoming widely recogni …

Glenohumeral contact force, peak muscle forces, and thorax motion increase with fatiguing wheelchair propulsion in persons with a spinal cord injury.

Shoulder problems are highly prevalent among manual wheelchair users with spinal cord injury, affecting their functioning and quality of life. This study investigates the impact of fatigue on wheelchair propulsion technique and shoulder loading in manual wheelchair users (MWU) with SCI. Twelve MWU with a paraplegia performed a standardized fatiguing wheelchair propulsion protocol; a biomechanical assessment of treadmill propulsion was obtained before and after the fatiguing protocol. Rate of perceived exertion (RPE), upper extremity kinematics, and wheelchair propulsion kinetics were assessed.…

Impact of motor fatigue on spatiotemporal parameters of gait under single-and dual-task conditions in individuals with chronic ankle instability and copers.

INTRODUCTION: Chronic ankle instability (CAI) is associated with altered gait mechanics and cognitive-motor deficits, while some individuals with a history of ankle sprain recover successfully as copers. Dual-tasking and fatigue represent common real-world challenges, but their combined effects on gait in CAI compared with copers remain unclear. PURPOSE: To investigate the effects of motor fatigue on spatiotemporal gait parameters under single- and dual-task conditions in individuals with CAI compared with copers. METHODS: Thirty individuals with CAI (mean age 26.7 ± 7.2 years) and 30 age- a…

Age-specific effects of a sustained cognitive activity on perceived cognitive fatigue as well as single- and dual-task treadmill walking performance.

During their daily lives humans are often confronted with sustained cognitive activities (SCA) leading to state fatigue, a psychobiological state characterized by a decrease in cognitive and/or motor performance and/or an increase in perception of fatigue. It was recently shown that performing SCA can impair overground dual-task gait performance in older adults, but it is currently unknown whether there is a task- and/or age-specific modulation in gait performance during treadmill walking. Therefore, the effect of a SCA on single- and dual-task treadmill walking performance was investigated in…

The Effect of progressive muscle relaxation and physical exercises on subjective well-being and fatigue of patients receiving hemodialysis: a randomized clinical trial.

Patients receiving hemodialysis (HD) often experience fatigue and reduced quality of life due to the chronic physical and psychological burden of treatment. Non-pharmacological interventions, such as Progressive Muscle Relaxation (PMR) and Physical Exercise (PE), show promise in alleviating these symptoms. This study aimed to compare the effects of PMR and PE on subjective well-being and fatigue in patients with HD. An individually randomized parallel-group trial was conducted with 66 patients receiving hemodialysis recruited from two centers in Mashhad, Iran. Participants were randomly assign…

The efficacy of lavender oil on fatigue and sleep quality in patients with hematological malignancy receiving chemotherapy: a single-blind randomized controlled trial.

PurposeThe aim of this study is to evaluate how aromatherapy with the inhalation of lavender oil affects fatigue and sleep quality in patients with hematological malignancies undergoing chemotherapy.MethodsThis randomized, parallel-group study was carried out in the Adult Bone Marrow Transplant unit and Hematology-Oncology clinics between January 2022 and April 2023. A total of 120 patients were assigned to experimental and control groups by randomization. The study was completed with 100 patients including 50 in the experimental group and 50 in the control group. Lavender essential oil was ap…