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Using nominal group technique to compare patients' and clinicians' perspectives on symptoms in multiple myeloma to inform the development of a self management tool for patients with relapsed myeloma.

BackgroundThe nominal group technique (NGT) allows stakeholders to directly generate items for needs assessment. The objective was to demonstrate the use of NGT to inform the development of a healthcare app in patients with relapsed myeloma. Healthcare professionals with experience in the care of patients with relapsed/refractory myeloma were invited to participate.MethodsOne NGT group was conducted. In the group, health care professionals working in haematology were asked to vote anonymously in order of highest priority, on symptoms previously highlighted by relapsed/refractory myeloma patien

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… . : Using a modified nominal group technique as a curriculum evaluation tool. Fam Med. 2004;36(6):402–6. 23. Cormican O, Dowling M: Supplementary_File_1 Voting Card.docx. figshare. Figure.2021. 10.6084/m9.figshare.13954283.v1 …

Emergency Department Management of Common End-of-Life and Palliative Care Symptoms: Three Cases

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… In a study, emergency medicine (EM) residents ranked pain and dyspnea management as 1st and 3rd, respectively, in terms of important topics for a PC curriculum [ 4 ]. EM residents reported minimal training in pain management and managing hospice patients [ 4 ]. …

Недооцененная причина гиперкальцемии: доклад о деле о синдроме Молка-Алкали.

Молоко-щелочный синдром (MAS) был впервые охарактеризован как отрицательное воздействие режима Sippy, в котором содержится большое количество бикарбоната натрия, что создает клинический сценарий, в котором гиперкальцемия, метаболический алкалоз и острая почечная недостаточность могут создать одновременные характеристики MAS. Синдром возобновился из-за широкого применения добавок кальция. A 50-year-old Белая женщина была доставлена в отделение скорой помощи ее врачом-терапевтом после случайного обнаружения гиперкальцемии во время проверки на усталость. У нее диагностировали острую почечную недо

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… Fayyaz A Scofield RH 1 3 3 2016 16 Milk-alkali syndrome is a major cause of hypercalcaemia among non-end-stage renal disease (non-ESRD) inpatients Clin Endocrinol (Oxf) Picolos MK Lavis VR Orlander PR 566 576 63 2005 16268810 10.1111/j.1365-2265.2005.02383.x 17 Calcium and phosphate disorders: core curriculum …

Establishing Hematopoietic Stem Cell Transplant Unit in Resource Limited Setting: A Critical Analysis of Indian Council of Medical Research 2017 Guidelines.

The scope and application of hematopoietic stem cell transplantation are increasing. With advancement in science and close cooperation of health centers, HSCT units are coming up in new developing and underdeveloped countries. India hosts many HSCT units and often provides financially viable option for HSCT to foreign patients as well. Recently Indian Council of Medical Research (ICMR) issued a guideline about HSCT unit in India. This review article discusses establishment of new HSCT unit in resource limited setting. Subsequent implication of ICMR guideline has been done.

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… In India, on request, curriculum based observership at an established SCT unit is a usual practice to gain experience and confidence. 6. Person Training Sustained availability of trained personnel is one of the main hurdles in advanced care units. …

Treatment of cancer with oral drugs: a position statement by the Spanish Society of Medical Oncology (SEOM).

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… Hansen HH Bajorin DF Muss HB Recommendations for a global core curriculum in Medical Oncology Ann Oncol 2004 15 1603 1612 15520060 10.1093/annonc/mdh447 4. EMEA EPARs for authorised medicinal products for human use http://www.emea.europa.eu/htms/human/epar/a.htm 5. …

Clinical Posters From JADPRO Live 2023.

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Membranous nephropathy: pathogenesis and treatments.

Membranous nephropathy (MN), an autoimmune disease, can manifest at any age and is among the most common causes of nephrotic syndrome in adults. In 80% of cases, the specific etiology of MN remains unknown, while the remaining cases are linked to drug use or underlying conditions like systemic lupus erythematosus, hepatitis B virus, or malignancy. Although about one-third of patients may achieve spontaneous complete or partial remission with conservative management, another third face an elevated risk of disease progression, potentially leading to end-stage renal disease within 10 years. The i

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… Membranous nephropathy: core curriculum 2021. Am J Kidney Dis. 2021;77(3):440‐453. 18. Beck LH, Bonegio RGB, Lambeau G, et al. M‐type phospholipase A 2 receptor as target antigen in idiopathic membranous nephropathy. N Engl J Med. 2009;361(1):11‐21. 19. Tomas NM, Hoxha E, Reinicke AT, et al. … Update on the native kidney biopsy: core curriculum 2019. Am J Kidney Dis. 2019;73(3):404‐415. 125. Floege J, Johnson RJ, Gordon K, et al. Altered glomerular extracellular matrix synthesis in experimental membranous nephropathy. Kidney Int. 1992;42(3):573‐585. 126. …

Health literacy, eHealth literacy and their association with burden, distress, and self-efficacy among cancer caregivers.

PurposeHealth literacy skills are vital for cancer caregivers in helping cancer survivors to navigate their diagnosis, treatment, and recovery but little is known. This study explored health literacy and eHealth literacy among cancer caregivers and the relationship between health literacy/eHealth literacy and potential associated factors.MethodsInformal caregivers who had cared for an individual with cancer completed a survey which collected demographic data and measured caregiver health literacy, eHealth literacy, self-efficacy, burden, and distress.ResultsSeven percent of caregivers had inad

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… Research is currently being conducted in areas related to improving similar health literacy capacities among cancer caregivers as those which caregivers found challenging in our sample; for example, the development of a communication and health literacy curriculum for caregivers ( Wittenberg et al., … Development of a communication and health literacy curriculum: optimizing the informal cancer caregiver role. Psychooncology 29, 766–774. doi: 10.1002/pon.5341 Yuen E. Y. N., Dodson S., Batterham R. W., Knight T., Chirgwin J., Livingston P. M. (2016). …

Interventions that address institutional child maltreatment: An evidence and gap map.

BACKGROUND: Child maltreatment has serious short and long-term negative impacts for those experiencing it. Child maltreatment occurring in i … however more than half (52%) were undertaken in the United States. Overall, most studies evaluated curriculum-based interventions delivered in educational settings, primarily aimed at the prevention of sexual abuse. Institutional setting: Most studies evaluated interventions in school or early learning environments (n = 8 systematic reviews; n = 58 primary …

Effects of total fat intake on bodyweight in children.

BACKGROUND: As part of efforts to prevent childhood overweight and obesity, we need to understand the relationship between total fat intake … -0.60 kg, 95% CI -2.39 to 1.19; n = 612; low-quality evidence). Education delivered as a classroom curriculum probably decreased BMI in children at 17 months (MD -1.5 kg/m2, 95% CI -2.45 to -0.55; 1 RCT; n = 191; moderate-quality evidence). The effects were smaller at longer term follow-up (five years: MD 0 kg/m2, 95% CI -0.63 to 0.63; n = 541; seven years; …

12th WINFOCUS world congress on ultrasound in emergency and critical care.

A1 Point-of-care ultrasound examination of cervical spine in emergency departmentYahya Acar, Onur Tezel, Necati SalmanA2 A new technique in … men by point-of-care ultrasoundHsiu-yung Pan, Chia-Te KungA40 Developing a point-of-care ultrasound curriculum for pediatric nurse practitioners practicing in the pediatric emergency departmentSarah Pasquale, Stephanie J. Doniger, Sharon Yellin, Gerardo ChiricoloA41 Use of transthoracic echocardiography in emergency setting: patient with mitral valve abscess …

Ускорение " Метаболомического старения " и его связи с социальными детерминантами здоровья в условиях множественного склероза.

ЦЕЛИ: Биологический возраст может лучше зафиксировать различия в курсе болезней среди людей с множественным склерозом (PwMS) одного и того же хронологического возраста. Мы изучили вопрос об ускорении биологического возраста на основе метаболомического возраста (mAge) в PwMS и его связи с социальными детерминантами здоровья (SDOH), измеряемыми по индексу лишений района (ADI).МЕТОДЫ: mAge был рассчитан для three Категории: 323 ПВМС и 66 - здоровый контроль (НС); 101 ГК и 71 DMT-naive PwMS; и 64 ГК и 67 Пациенты с синдромом MS/клинической изоляции с использованием стареющих часов, полученных из 1

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… Waubant is funded by the NIH, NMSS, DoD, and Race to Erase MS, She has received honoraria for talks from Neurology Live, and Advanced Curriculum, She is volunteering on a DSMB for a BMS trial and an advisory board for a Roche trial; E.M. …

Последствия программы, основанной на модели адаптации Роя, в отношении навыков обучения детей с множественным склерозом.

СПРАВОЧНАЯ ИНФОРМАЦИЯ: На здоровье детей влияет множественный склероз (МС) у их родителей и различные его осложнения. С учетом этого, это исследование было проведено с целью изучения воздействия программы, основанной на модели адаптации Роя, на способности детей пациентов с синдромом MS. МАТЕРИАЛЫ И МЕТОДЫ: 78 детей 78 Пациенты MS из Ассоциации поддержки MS в Шахрекорде, в том числе около 1800 пациенты 2018 с использованием квазиэкспериментального метода. Образцы были отобраны с помощью удобного метода отбора проб, и они заполнили контрольный перечень, подготовленный исследователями, на основе

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… June H Colleen HJ Nursing Practice in Multiple Sclerosis: A Core Curriculum 4th New york Springer Publishing Company 2016 25. Barker E Neuroscience Nursing: A Spectrum of Care 3rd St. Louis Mosby 2007 26. …

Preventive strategies for acute kidney injury in cancer patients.

Acute kidney injury (AKI) is a common complication of cancer that occurs in up to 50% of neoplastic patients during the natural history of their disease; furthermore, it has a huge impact on key outcomes such as overall prognosis, length of hospitalization and costs. AKI in cancer patients has different causes, either patient-, tumour- or treatment-related. Patient-related risk factors for AKI are the same as in the general population, whereas tumour-related risk factors are represented by compression, obstruction, direct kidney infiltration from the tumour as well by precipitation, aggregatio

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… Dysproteinemia and the kidney: core curriculum 2019 . Am J Kidney Dis 2019 ; 74 : 822 – 836 31331759 10.1053/j.ajkd.2019.04.029 19 Finkel KW , Cohen EP , Shirali A et al. ; American Society of Nephrology Onco-Nephrology Forum. … Management of acute kidney injury: core curriculum 2018 . Am J Kidney Dis 2018 ; 72 : 136 – 148 29478864 10.1053/j.ajkd.2017.11.021 56 Cortazar FB , Kibbelaar ZA , Glezerman IG et al Clinical features and outcomes of immune checkpoint inhibitor-associated AKI: a multicenter study . …

Coexistence of double seropositivity for MPO antibody and anti-GBM antibody in ANCA-associated vasculitis concurrent with multiple myeloma: A case report.

RationaleImmune-mediated vasculitis with 2 or more autoantibodies, for example, anti-proteinase-3, combined with anti-myeloperoxidase (MPO) or anti-glomerular basement membrane (GBM) antibodies, is extremely unusual. Furthermore, the coexistence of autoimmune vasculitis and hematological malignancies is uncommon. Herein, we describe a case of double-seropositive anti-neutrophil cytoplasmic antibody (ANCA) vasculitis with multiple myeloma.Patient concernsA 79-year-old Asian man presented with persistent leg edema and kidney dysfunction. His kidney function rapidly decreased, and serologic test

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… ANCA-associated vasculitis: core curriculum 2020. Am J Kidney Dis. 2020;75:124–37. [2] Parmar MS, Bashir K. Crescentic glomerulonephritis [Updated February 20, 2023]. StatPearls. Treasure Island: StatPearls; 2024. https://www.ncbi.nlm.nih.gov/books/NBK430727/ . …

Renal Involvement in Cancer Patients Undergoing Oncology Therapies: Implications for Personalized Treatment Strategies.

Introduction: Oncological therapies have significantly improved patient outcomes but are increasingly associated with renal toxicity, which can markedly influence therapeutic decisions. Integrating early identification of kidney injury into clinical workflows is essential for personalized medicine, allowing treatment tailoring based on individual risk profiles. Aim: To evaluate the incidence of acute kidney injury (AKI) and chronic kidney Disease (CKD); assess indices of renal function recovery in patients who developed AKI; and investigate the incidence of renal immune-related adverse events

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… Onconephrology: Core Curriculum 2023 Am. J. Kidney Dis. 2023 82 743 761 10.1053/j.ajkd.2023.04.014 37855786 19. Lameire N.H. Flombaum C.D. Moreau D. Ronco C. Acute renal failure in cancer patients Ann. Med. 2005 37 13 25 10.1080/07853890510007205 15902843 20. Lai S. Amabile M.I. Mazzaferro S. …

Medication-related osteonecrosis of the jaw: who knows more? A cross-sectional study of general dental practitioners and oral maxillofacial surgery assistants.

BACKGROUND/OBJECTIVES: Anti-resorptive and anti-angiogenic drugs, commonly prescribed for osteoporosis, bone metastases, and metabolic bone diseases, increase the risk of medication-related osteonecrosis of the jaw (MRONJ) following dentoalveolar surgery. This study aimed to assess the knowledge of general dental practitioners and oral and maxillofacial surgery (OMFS) assistants regarding these drugs, MRONJ, and related treatment approaches. Methods: A questionnaire addressing demographics, familiarity with these medications, understanding of MRONJ, and treatment strategies was electronically

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… Understanding these differences can guide curriculum improvements and targeted continuing education programs to enhance practice. …

Инфодемиология и инфовелленс множественных склерозов в Италии

Множественный склероз (MS) является хроническим изнурительным заболеванием вероятной аутоиммунной провокационной природы, аэтология которого не в полной мере понята, несмотря на многочисленные усилия и исследования. В этой рукописи мы пересматриваем концепцию < < мультипликаторного склероза 2.0 > > , т.е. использование Интернета пациентами, страдающими MS, для поиска медицинских и связанных с болезнями материалов для целей самообслуживания и саморегулирования, и внедряем основанный на Google Trends подход к мониторингу связанных с MS запросов и поисков в Google, который называется

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… 4422(08)70252-7 15 Blanch D Sciamanna C Lawless H Diaz J Effect of the internet on the doctor-patient relationship: a review of the literature Journal on Information Technology in Healthcare 2005 3 3 179 201 2-s2.0-26844534596 16 Kim JY Gudewicz TM Dighe AS Gilbertson JR The pathology informatics curriculum …

London Trauma Conference 2015 : London, UK, 8-11 December 2015.

I1: Trauma, Pre-hospital and Cardiac Arrest Care 2015 Pascale Avery, Leopold Salm, Flora Bird A1: Retrospective evaluation of HEMS ‘Direct t … non-trauma patients presenting to the Emergency Department? Josephine Murray, Malcolm Tunnicliff A6 Curriculum mapping in ED point of care simulation Joseph W Collinson, Thomas Brown, Christopher Pritchett A7 Point of care multidisciplinary trauma team simulation & participant satisfaction in a geographically remote trauma unit in Cornwall Christopher SA Pri …

Taming renal inflammation: signaling pathways and therapeutic advances in lupus nephritis.

Lupus nephritis (LN), a serious complication of systemic lupus erythematosus (SLE), involves complex immune dysregulation that leads to chronic renal inflammation and progressive tissue damage. Despite decades of use of standard immunosuppressive therapy, treatment responses remain variable, and many patients experience relapses or develop end-stage renal disease. This review synthesizes emerging insights into the immunopathogenesis of LN, drawing on studies from single-cell transcriptomics, signaling pathway analyses and renal tissue immunology. It examines the role of both innate and adaptiv

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… Parikh SV Almaani S Brodsky S Rovin BH Update on lupus nephritis: core curriculum 2020 Am J Kidney Dis 2020 76 2 265 81 32220510 10.1053/j.ajkd.2019.10.017 Parikh SV, Almaani S, Brodsky S, Rovin BH. Update on lupus nephritis: core curriculum 2020. …