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Italian onco-haematological patients' preferences in bad news communication: a preliminary investigation.

BackgroundThe manner in which bad news is communicated in oncological contexts can affect patients' engagement, their coping strategies and therapeutic compliance. Although this topic has been broadly investigated since the nineties, to the best of our knowledge, little has been written about Italian patients' experiences and preferences concerning what the oncologists should disclose and how they should intimate patients about their health conditions in different stages of oncological disease.MethodsIn an attempt to fill this gap, an online self-report questionnaire was administered to a samp

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… Regarding traditional practices of concealment of the truth by physicians, a qualitative research on Italian medical students about the contents conveyed by the hidden curriculum has highlighted that students were exposed to a culture of emotional detachment and partial unveiling of the information to … How Italian students learn to become physicians: a qualitative study of the hidden curriculum. Medical Teacher. 2011;33(12):989–996. doi: 10.3109/0142159X.2011.577467. 79. Gordon DR, Paci E. …

The Crystalline Nephropathies.

Crystalline nephropathies are a unique form of kidney disease characterized by the histologic finding of intrarenal crystal deposition. The intrinsic nature of some molecules and ions combined with a favorable tubular fluid physiology leads to crystal precipitation and deposition within the tubular lumens. Crystal deposition promotes kidney injury through tubular obstruction and both direct and indirect cytotoxicities. Further kidney injury develops from inflammation triggered by these crystals. From a clinical standpoint, the crystalline nephropathies are associated with abnormal urinalysis a

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… Urine sediment examination in the diagnosis and management of kidney disease: core curriculum 2019 Am J Kidney Dis 73 2019 258 272 10.1053/j.ajkd.2018.07.012 30249419 15 Slade H. Mulroy E. Ussher J. Putt T. Schollum J. Walker R. … Dysproteinemia and the kidney: core curriculum 2019 Am J Kidney Dis 74 2019 822 836 10.1053/j.ajkd.2019.04.029 31331759 55 Rosner M.H. Jhaveri K.D. McMahon B.A. Perazella M.A. …

Keyword Index for Volume 108

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… 1846 comprehensive geriatric assessment 1936 consultations 686 conventional adenocarcinoma 613 COP1 2495 cost 1225, 2250 cost-effectiveness 9, 1579, 2250 COX-2 91, 1106, 2272 COX-2 inhibitor 319 Cox 784 C-reactive protein 1891 cross-sectional studies 292 CRPC 1668 cryptic 1113 CTC 2426 curriculum …

Multidisciplinary Approach to Older Adults with Hematologic Malignancies-a Paradigm Shift.

Hematologic malignancies are most likely to present in the seventh and eighth decades of life. Continued population growth will lead to increasing numbers of older adults with hematologic malignancies. Oncology care for older adults is complex and must account for the effect of aging on disease biology and treatment tolerance. Multidisciplinary oncology care has been utilized in solid tumor oncology for decades, initially driven by the need for multi-modality treatment. In this review, we make the case for multidisciplinary oncogeriatric care for older adults with hematologic malignancies in o

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… Outpatient care systems, in Geriatrics review syllabus: a core curriculum in geriatric medicine. D. A, S. G, Editors. 2013, American Geriatrics Society: New York. p. 189. 5. Campbell LJ, Cole KD. Geriatric assessment teams. …

Do Legal Issues Deserve Space in Specialty Medical Journals ?

Physicians and Internists in India have tended to brush under the carpet legal issues affecting their profession. Of concern to all Physicia … er Consumer Protection Act hence differential liability is unacceptable. Training program and study curriculum of MD Medicine includes cardiology and the residents are posted in cardiology wards and ICCUs in all teaching institutions despite being only MBBS at the time. Though some institutions do not encourage active involvement in clinical care to be done …

Evaluating Therapeutic Plasma Exchange in Pediatric Acute Disseminated Encephalomyelitis: A Comprehensive Review.

Acute disseminated encephalomyelitis (ADEM) is a rare autoimmune disorder characterized by brain and spinal cord inflammation. In pediatric patients, ADEM presents unique challenges due to its potential for rapid progression and long-term neurological sequelae. Therapeutic plasma exchange (TPE) has emerged as a potential treatment option by targeting the underlying autoimmune process and modulating the inflammatory response. This comprehensive review evaluates the role of TPE in pediatric ADEM, synthesizing evidence from clinical studies and providing insights into its efficacy, safety, and po

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… Therapeutic plasma exchange: core curriculum 2023. Cervantes CE, Bloch EM, Sperati CJ. Am J Kidney Dis. 2023;81:475–492. doi: 10.1053/j.ajkd.2022.10.017. 26. …

Current progress in CAR-based therapy for kidney disease.

Despite significant breakthroughs in the understanding of immunological and pathophysiological features for immune-mediated kidney diseases, a proportion of patients exhibit poor responses to current therapies or have been categorized as refractory renal disease. Engineered T cells have emerged as a focal point of interest as a potential treatment strategy for kidney diseases. By genetically modifying T cells and arming them with chimeric antigen receptors (CARs), effectively targeting autoreactive immune cells, such as B cells or antibody-secreting plasma cells, has become feasible. The emerg

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… ANCA-associated vasculitis: core curriculum 2020 . Am J Kidney Dis . ( 2020 ) 75 : 124–37 . doi: 10.1053/j.ajkd.2019.04.031 31358311 95 Jennette JC Falk RJ . Pathogenesis of antineutrophil cytoplasmic autoantibody-mediated disease . … Dysproteinemia and the kidney: core curriculum 2019 . Am J Kidney Dis . ( 2019 ) 74 : 822–36 . doi: 10.1053/j.ajkd.2019.04.029 31331759 123 Vaxman I Gertz M . Recent advances in the diagnosis, risk stratification, and management of systemic light-chain amyloidosis . …

Quality of life and financial toxicity of hematopoietic stem cell transplant recipients in COVID-19.

Objectiveto evaluate and correlate the quality of life and financial toxicity of adult patients undergoing hematopoietic stem cell transplantation during the COVID-19 pandemic.Methodobservational, analytical study, carried out with 35 patients in a reference hospital for transplantation in Latin America. For data collection, the Functional Assessment Cancer Therapy Bone Marrow Transplantation and COmprehensive Score for Financial Toxicity questionnaires were used. Spearman and Mann-Whitney correlation tests were used for data analysis.Resultsgeneral quality of life during COVID-19 had a low sc

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… The HSCT Unit - Recommendations from the European Society for Blood and Marrow Transplantation (EBMT) for a curriculum in hematopoietic cell transplantation. Springer; Cham: 2023. Daudt L. E., Corso M. C. M., Kerbauy M. N., Assis L. H. D. S., Rechenmacher C., Couturato I. …

Clusters of Comorbidities in the Short-Term Prognosis of Acute Heart Failure among Elderly Patients: A Retrospective Cohort Study.

Background and Objectives: Elderly patients affected by acute heart failure (AHF) often show different patterns of comorbidities. In this paper, we aimed to evaluate how chronic comorbidities cluster and which pattern of comorbidities is more strongly related to in-hospital death in AHF. Materials and Methods: All patients admitted for AHF to an Internal Medicine Department (01/2015−01/2019) were retrospectively evaluated; the main outcome of this study was in-hospital death during an admission for AHF; age, sex, the Charlson comorbidity index (CCI), and 17 different chronic pathologies were i

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… Management of Heart Failure in Advancing CKD: Core Curriculum 2018 Am. J. Kidney Dis. 2018 72 284 295 10.1053/j.ajkd.2017.12.006 29478868 11. Heywood J.T. Fonarow G.C. Costanzo M.R. Mathur V.S. Wigneswaran J.R. Wynne J. …

Symptomatic spinal epidural lipomatosis after combined hormonal and steroidal palliative therapy of prostate cancer.

To meet the demand for kidney transplants (KTx), organs are frequently retrieved not only from standard criteria donors (SCD; a donor who is aged <50 years and suffered brain death from any number of causes, such as traumatic injuries or a stroke) but also from expanded criteria donors (any donor aged >60 years or donors aged >50 years with two of the following: A history of high blood pressure, a creatinine serum level ≥1.5 mg/dl or death resulting from a stroke). This comes at the cost of a higher risk of primary non‑function (the permanent hyperkalemia, hyperuremia and fluid overload that r

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… Reforming the undergraduate nursing clinical curriculum through clinical immersion: a literature review. Nurse Educ Pract. 2018;31:68–76. doi: 10.1016/j.nepr.2018.04.013. 9. Geist MJ, Sanders R, Harris K, Arce-Trigatti A, Hitchcock-Cass C. …

Полуобучение для прогнозирования множественного склероза.

Фон: Множественный склероз (MS) — хроническое аутоиммунное заболевание центральной нервной системы с склонностью вызывать серьезные неврологические расстройства. Точное и раннее прогнозирование прогресса в области НР имеет исключительно важное значение для управления им и его лечения. Методы: В настоящем документе мы сравниваем ряд самомаркированных полуконтролируемых методов обучения, используемых для прогнозирования MS на основе маркированных и немаркированных медицинских данных. В частности, мы сравниваем результаты самоподготовки, СЕТРЕД, совместной подготовки, совместной подготовки с Коми

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… The dataset, which was gathered by the curriculum of [ 27 ], provides valuable information on numerous clinical, demographic, and imaging-derived variables that have the potential to influence disease course. …

Переход от педиатрической помощи к альтернативной склерозовой терапии для взрослых: проблемы, стратегии и терапия.

Множественный склероз (MS) — хроническое аутоиммунное состояние, вызывающее повреждение защитного покрытия нервов в центральной нервной системе. Педиатрический множественный склероз является редкой формой болезни, которая затрагивает 3-5% лиц с множественным склерозом. Множественный склероз (POMS) у педиатрии Onset (Podiatric Onset Multical Sclerosis) имеет весьма иной клинический профиль по сравнению с более распространенным множественным склерозом у взрослых. Помимо классических симптомов множественного склероза, дети, как правило, испытывают различные нетипичные симптомы, которые могут влия

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… we can implement in our practice are the “Transition Youth Registry” to track the progress of each patient in the transition process, and a “Longitudinal Readiness Checklist” to assess the adolescent's ability for independence and self-management. 61 Transition of care should also be part of the curriculum …

Emphasizing Patient-Centricity Through a Tailored Training Program to Empower Patients, Advocates, and Ethics Committees in Good Clinical Practice.

ObjectivesGood Clinical Practices (GCP) are essential for patient-centric research. The standard bioethics and GCP training emphasizing a "one-size-fits-all" approach may not adequately equip ethics committee members, especially the lay and social scientist members, towards their critical role in reviewing clinical trials and related documentation. This article explores a patient-centered, patient advocates-driven training program focused on raising awareness about research ethics and GCP among patients, advocates and ethics committee members.MethodsA patient advocates-driven program called Pa

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… The collaborative effort of NPSIF with medical, nursing and pharmacy programs to integrate the World Health Organization’s (WHO) Patient Safety Curriculum in education program will equip future healthcare professionals to prioritize patient safety [ 24 ]. …

India's Growing Nuclear Medicine Infrastructure and Emergence of Radiotheranostics in Cancer Care: Associated Challenges and the Opportunities to Collaborate.

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… Similarly, many of the world renowned theranostic centers in Western World have trained several Indian research fellows who have now taken center stage at the global level and are actively involved in formulating a curriculum for preparing “Nuclear Oncologists.” …

An approach to treating older adults with chronic kidney disease.

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… In addition, we reviewed current European, American and Canadian guidelines on the management of chronic kidney disease and hypertension including Kidney Disease: Improving Global Outcomes, Hypertension Canada 2017, and American Society Nephrology Geriatric Nephrology Curriculum. …

Spiritual Needs and Quality of Life of Patients with Cancer.

Background and aimInformation about spiritual needs and quality of life (QoL) is limited in Iranian cancer patients. This study was conducted to determine the relationship between spiritual needs and QoL among cancer patients in Iran.MethodsThis correlational study included a convenience sample of 150 eligible cancer patients who were hospitalized in the oncology wards and outpatient clinics. Using two questionnaires; the spiritual needs survey and the European Organization for Research and Treatment of Cancer QoL Questionnaire-C30 data were collected. The data were analyzed by SPSS software v

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… In addition, spiritual needs to become part of every nursing curriculum, and nurses should be offered continuing education that will enable them to better support patients with cancer. …

The Influence of Hospice-Palliative Nursing Knowledge, Empathy, and Attitude toward End-of-Life Care on Spiritual Care Competence of Nurses in Long-Term Care Hospital.

PURPOSE: This study was conducted to identify the influence of hospice·palliative nursing knowledge, empathy, and attitudes toward end-of-life care on spiritual care competence of nurses in long-term care hospitals. METHODS: The participants was 174 nurses who had worked for more than one clinical year and experienced end-of-life care more than one time in 14 long-term-care hospitals in C province. Data were collected using questionnaires which consisted of hospice·palliative care knowledge, empathy, attitude toward end of life care, and spiritual care competence. Data were analyzed using the

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… We believe that the difference in curriculum and duration of studies between 3-year colleges and 4-year colleges might affect opportunities to learn about hospice and palliative care. …

Fibrinogen/albumin ratio is associated with first-ever cardiovascular events in patients with peritoneal dialysis.

OBJECTIVE: The fibrinogen/albumin ratio (FAR) is a novel inflammatory indicator, which has been associated with cardiovascular disease. However, the relationship between FAR and cardiovascular event (CVE) in patients with peritoneal dialysis (PD) remains unclear. This study aims to clarify the relationship between FAR and first-ever CVE in patients with PD. METHODS: A total of 278 patients were enrolled between January 2012 and June 2021. They were defined as the high FAR group and the low FAR group based on the median FAR value (0.107). The primary outcome was the occurrence of first-ever CV

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… Peritoneal dialysis prescription and adequacy in clinical practice: core curriculum 2023. Am J Kidney Dis. 2023;81(1):100–109. doi: 10.1053/j.ajkd.2022.07.004. 2. Ng CH, Ong ZH, Sran HK, et al. Comparison of cardiovascular mortality in hemodialysis versus peritoneal dialysis. …

HealthTree Cure Hub: A Patient-Derived, Patient-Driven Clinical Cancer Information Platform Used to Overcome Hurdles and Accelerate Research in Multiple Myeloma.

PurposeThe study of rare diseases, such as multiple myeloma (MM), often experiences unique research hurdles that can delay or prevent lifesaving discoveries. HealthTree Cure Hub is a first-in-class software program designed to overcome these potential research hurdles.MethodsWe assessed whether HealthTree Cure Hub improved four commonly experienced research hurdles such as (1) small numbers of patient accrual to clinical trials and research studies, (2) shallow and isolated data sets, (3) high costs to answer research questions, and (4) lack of long-term follow-up patient data.ResultsAs of Jun

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… Patients were also able to view crowdsourced side-effect solutions, become educated using a comprehensive online myeloma curriculum in HealthTree University, participate in community forums, find a Myeloma HealthTree Coach, contribute to research, or interact with live reports. …

Clinical Posters From JADPRO Live 2024

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… Applicants were required to submit a curriculum vitae, letter of intent, a letter of support from a sponsoring physician, and were interviewed by phone. Grant funding was secured for full scholarships to 21 selected OAPs representing 16 major cancer centers (1 in Australia). … This information was subsequently incorporated into the curriculum for patients initiating oral chemotherapy. Nursing knowledge, beliefs, and attitudes were evaluated before and after the subject-intensive education. …