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Q fever: a biological weapon in your backyard.

Coxiella burnetii, which causes Q fever, is a highly infectious agent that is widespread among livestock around the world. Although the culture process for coxiella is laborious, large amounts of infectious material can be produced. If used as an aerosolised biological weapon, coxiella may not cause high mortality, but could provoke acute disabling disease. In its late course, Q fever can be complicated by fatal (eg, endocarditis) or debilitating (eg, chronic fatigue syndrome) disorders. The diagnosis of Q fever might be delayed because of non-specific and protean presentations. Effective anti…

African tick bite fever: not a spotless rickettsiosis!

African tick bite fever is caused by Rickettsia africae, a newly recognized species from South Africa. We report the case of a patient with an unusual site of a tick bite and discuss cutaneous differences from other spotted fevers that may help dermatologists with clinical diagnosis.

[Epidemiological pattern of scarlet fever in recent years].

During the period of 1953-2001 scarlet fever morbidity level fluctuated from 670.3 to 65.9 per 100,000 of the population in Moscow and from 531.9 to 35.0 per 100,000 of the population of the Russian Federation. In recent years an increased morbidity was more pronounced in Moscow than in the Russian Federation as a whole. Children formed the greater part of scarlet fever patients, the cases of scarlet fever among children in Moscow occurring more often than, on the average, in Russia. As before, annual morbidity among children attending children's institutions was higher 3- to 4-fold than among…

Reactive airways dysfunction syndrome following metal fume fever.

Metal fume fever (MFF) is an acute response to the inhalation of heavy metals used in industry. The patient typically experiences symptoms of cough, fever, chills, malaise, and myalgia that are self-limited and of short duration. Wheezing may occur and pulmonary function may be acutely impaired with a decrease in lung volumes and diffusing capacity of carbon monoxide. Nevertheless, respiratory function quickly returns to normal, and persistent pulmonary insufficiency is unusual. Irritant-induced asthma is a non-immunogenic form of airway injury that may be associated with industrial inhalation…

Rheumatic Fever and Long-term Sequelae in Children.

Rheumatic fever and rheumatic heart disease continue unabated, affecting young individuals in most of the developing nations. Focal outbreaks of smaller magnitude have also been reported since the mid-1980s from industrialized western nations, where this disease had almost disappeared. The introduction of penicillin in the mid-1940s has markedly changed the natural history of rheumatic fever, although the incidence of rheumatic fever declined in developed nations even before that, mainly due to better living conditions. Treatment of rheumatic fever chiefly involves the use of antibiotics (peni…

Dengue hemorrhagic fever in a British travel guide.

A 44-year-old female British travel guide suddenly had fever, nausea, vomiting, and diarrhea develop during her stay in South India. Four days later she was transported to our hospital. At admission she had a high temperature, impaired respiration, and abdominal pain. Clinical examination revealed bilateral pleural effusion, hepatomegaly, and ascites. Two days later the patient showed a generalized macular rash with a conspicuous sparing of small islands of normal skin. Hemorrhagic erythema on the palms and soles as well as focal petechiae on the hard palate and scleral and conjunctival bleedi…

Гантавирусный легочный синдром: новая американская геморрагическая лихорадка.

Признание хантавирусного легочного синдрома (HPS) после исследования группы необъяснимых случаев смерти дыхательных путей в юго-западной части Соединенных Штатов весной 1993 года продемонстрировало нашу способность распознавать новые и возникающие заболевания, учитывая правильное сочетание нового клинического образования с ограниченными эпидемиологическими характеристиками, которые анализируются с помощью новых диагностических методов. Менее чем за десять лет HPS стал панамериканским зоонозом благодаря многочисленным вирусам, поддерживаемым грызунами с грызунами и вирусными эпидемиологическими

Совпадение в аннотации оригинала
The recognition of hantavirus pulmonary syndrome (HPS) after the investigation of a cluster of unexplained respiratory deaths in the southwe … luding disease with frank hemorrhage, that have confirmed that this syndrome is a viral hemorrhagic fever. Efforts are under way to refine prevention strategies, to understand the pathogenesis of the shock, and to identify therapeutic modalities.

Ampicillin use in infant fever: a systematic review.

OBJECTIVES: To estimate the prevalence of perinatal Listeria monocytogenes and enterococcal infections in outpatient febrile infants and to evaluate the need to treat with ampicillin. DATA SOURCES: Online bibliographies were searched for articles related to serious bacterial infection and fever in infants. Reference lists from selected and review articles were also examined. STUDY SELECTION: Studies that reported rates and types of bacterial infection in febrile outpatients younger than 3 months were included. Those performed outside North America, lacking results by age, or those that evalu…

[Clinical aspects of typhoid fever epidemic in migrants].

AIM: To study clinical features of typhoid fever (TF) in migrants (subjects in military service in Tadjikistan). MATERIAL AND METHODS: In chronic water epidemic TF symptoms were studied in 547 young soldiers and officers serving in Tadjikistan with incomplete biological and/or professional adaptation. RESULTS: In most cases TF onset was acute, the course was severe with fever and intoxication. TF clinical picture was similar to that of the beginning of the XX century. Despite antibiotic resistance of the causative agent, recurrences and serious complications were rare, lethal outcomes were n…

[Fever of unknown origin in HIV positive patients].

OBJECTIVES: To describe the clinical presentation of FUO in patients infected with HIV and to asses the diagnostic usefulness in this population of several test usually recommended in the study of FUO. PATIENTS AND METHODS: We studied the clinical charts of all patients with HIV that required admission to our Hospital during a 23-month period. FUO was defined according to Petersdorf's modified criteria. Fifty-four patients fulfilled study criteria during the entry period. RESULTS: A cause of fever was identified for 48 patients (89%). Tuberculosis, disseminated atypical mycobacteriosis and L…

Intractable Q fever treated with recombinant gamma interferon.

A 3-year-old boy with Q fever received several kinds of antibiotics including minocycline, but spiking fever and positive PCR of Coxiella burnetii continued for several months. He became asymptomatic and his abnormal laboratory data normalized after the administration of gamma interferon three times a week.

[Spotted fever group rickettsial disease in Argentinean travelers].

During 1996, four patients that returned from South Africa suffering from rickettsiosis were attended at the Traveler's Medicine practice of our hospital. All of them presented fever, headache and cutaneous scar. One of these presented maculopapular rash, while the rest developed a vesicular rash. The Weil-Felix reaction was negative and the immunofluorescence test for Rickettsia conorii was positive in all cases. None of the patients remembered having been bitten by any insects, however all of them had been staying in or going through a wild environment. All the patients were treated with dox…

Typhoid fever, ciprofloxacin and growth in young children.

Typhoid fever remains a significant public health problem in Southern Asia, particularly with the emergence of multi-resistant strains of Salmonella typhi in the late 1980s. Use of ciprofloxacin in children, although discouraged, is increasing and we aimed to assess whether its use affects growth or the prevalence of joint symptomology. Children under 6 years of age diagnosed as typhoid fever on the basis of a positive Widal test were recruited in the outpatient department of a paediatric teaching hospital after treatment had been initiated. During 6 months follow-up, prevalences of arthritis/…

[Fever after return from the tropics. Diagnostic orientation].

Fever is the main symptom of many tropical diseases (parasitic, bacterial and viral). After traveller's diarrhoea, it constitutes the principal reason of consultation of travellers from tropical area. The diagnosis requires a rigorous approach through a meticulous and an attentive clinical examination. Knowledge of the tropical disease epidemiology facilitates the diagnostic orientation. Complementary exams generally permit confirmation of the diagnosis. Malaria must be evoked at first for the traveller coming from an endemic area and deserves a precocious presumptive treatment. Nevertheless, …