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On the Occasion of the 80th Anniversary of the Faculty of Medicine of Charles University in Hradec Králové.

Last autumn we commemorated the 80th anniversary of the founding of the Faculty of Medicine of Charles University in Hradec Králové. A numbe … d civilian Faculty of Medicine of Charles University. Military students therefore complete the full curriculum of general medicine or dentistry, while additionally undergoing training in military-professional subjects, practical training in a vivarium or on simulators, and field exercises. In 1988, the institute was renamed again as the Military Medical Acad …

The Effect of Laughter Yoga on Chemotherapy-Induced Symptoms and Sleep Quality in Patients with Haematologic Cancer.

There are international studies that examine the effects of laughter yoga on the symptoms and quality of life of cancer patients as a complementary therapeutic method.AimThis study aims to examine the effect of laughter yoga on chemotherapy-induced symptoms and sleep quality in patients with haematologic cancer.Materials and methodsThis study was conducted as a randomised controlled trial with two parallel treatment arms. The study was between November 2020 and December 2021. The sample was calculated with 60 patients including in the study. A total of 4 sessions of laughter yoga were applied

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… Courses on the subject can be added to the curriculum of undergraduate education programs. It may be recommended that future studies be conducted with a larger sample group. Author Contribution Statement All authors contributed equally in this study. Acknowledgements None. References 1. …

Implementing calculated globulin screening for immunodeficiencies: The benefits and challenges.

There is a need for pragmatic and cost-effective methodologies to facilitate earlier diagnosis of patients with primary and secondary immunodeficiencies, who often experience diagnostic delays that impact their quality of life, morbidity, and mortality. This review article will consider the utility of calculated globulin (CG) as a simple and unbiased screening tool for immunodeficiencies. We review literature indicating that CG can serve as an inexpensive and routinely performed proxy for immunoglobulin levels due to their established correlation. We also set out a workflow for the implementat

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… Immune Deficiency . https://education.aaaai.org/clinical-rotation-curriculum/curriculum_immune_deficiency#group-tabs-node-course-default1 (accessed July 2025) . 31. European Society for Immunodeficiencies . 2025 . …

Associations among navigational support and health care utilization and costs in patients with advanced cancer: An analysis based on administrative health insurance data.

BackgroundFragmented and complex healthcare systems make it difficult to provide continuity of care for patients with advanced cancer near the end of life. Nurse-based cross-sectoral navigation support has the potential to increase patients' quality of life. The objective of this paper was to evaluate associations between navigation support and health care utilization, and the associated costs of care.MethodsThe evaluation is based on claims data from 37 statutory health insurance funds. Non-randomized recruitment of the intervention group (IG) took place between 2018 and 2019 in four German h

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… The three‐week training of the SCN is essentially based on the training curriculum for oncologists of the Saxon Cancer Society. 29 Patients Non‐randomized recruitment of the intervention group took place between February 1, 2018, and February 1, 2019, in four German hospitals. …

Fostering Patient Choice Awareness and Presenting Treatment Options Neutrally: A Randomized Trial to Assess the Effect on Perceived Room for Involvement in Decision Making.

PurposeShared decision making calls for clinician communication strategies that aim to foster choice awareness and to present treatment options neutrally, such as by not showing a preference. Evidence for the effectiveness of these communication strategies to enhance patient involvement in treatment decision making is lacking. We tested the effects of 2 strategies in an online randomized video-vignettes experiment.MethodsWe developed disease-specific video vignettes for rheumatic disease, cancer, and kidney disease showcasing a physician presenting 2 treatment options. We tested the strategies

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… An innovative shared decision-making curriculum for internal medicine residents: findings from the University of Pittsburgh Medical Center. Acad Med. 2018;93:937–42. 19. Simon D, Schorr G, Wirtz M, et al. Development and first validation of the shared decision-making questionnaire (SDM-Q). …

Clinical Posters From JADPRO Live 2025

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… The structure and curriculum for a twelve-month fellowship was developed using current literature and Advanced Practice Provider Fellowship Accreditation (APPFA) guidelines for certification. This structure included classroom and self-guided didactic experiences aligned with 11 clinical rotations. … Professional development activities were incorporated in the curriculum and the fellow was expected to complete a quality improvement project. APPs and physicians across several clinical areas served as faculty for classroom days. …

Development of a Mindfulness-Based Stress Reduction Program for Hematologic Malignancy Patients: A Delphi Study.

PurposeHematologic malignancies (HM) are a group of malignant clonal diseases that pose significant treatment challenges and adversely impact patient survival and quality of life. This study aimed to develop a Mindfulness-Based Stress Reduction (MBSR) program specifically for HM patients and to refine it for application in China.Patients and methodsA research team comprised of nursing directors, psychology experts, and other professionals was established, and then a literature review was conducted to assemble information needed to develop the MBSR intervention protocol. Following this, a Delph

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… A modified Delphi study on establishing a curriculum content structure for the leadership and management competency cultivation for future nurse managers in China. Heliyon . 2022;8(12):e12183. doi: 10.1016/j.heliyon.2022.e12183 29. Ebrahim H, Fisha T, Debash H, Bisetegn H. …

Mindfulness vs. sleep education during autologous hematopoietic cell transplantation for multiple myeloma: Feasibility of a randomized controlled pilot study.

BackgroundSleep disturbance is common in patients receiving hematopoietic stem cell transplantation (HCT). Mindfulness-based interventions (MBIs) can improve sleep quality during and following cancer treatment by reducing treatment-related symptoms and enhancing immune function.MethodsWe conducted a randomized controlled pilot study investigating the feasibility of implementing Mindfulness Awareness Practices for Insomnia (MAP-I) in patients with multiple myeloma (MM) undergoing autologous HCT. Patients were randomized to receive either MAP-I or a Sleep Health Education (SHE) intervention, bot

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… The MAP-I intervention is curriculum-based and consists of 6 videos delivered via the Teachable website. MAP-I was created by the Mindful Awareness Research Center at the University of California Los Angeles (UCLA) and was adapted for patients undergoing HCT. …

A Glimpse into the Epidemiology of Geriatric Cancers in India: Report from the Indian Population Based Cancer Registries.

IntroductionIndian population is aging and the cancer rates are rising. Older adults (OAs)(≥60 years) with cancer require specialized care. However, data on geriatric cancer epidemiology is scarce.MethodsThe study compiled the geriatric cancer data from the published reports(2012-2014) of Indian population-based cancer registries(PBCRs).ResultsOf the 1,61,363 cancers registered in the Indian PBCRs, 72,446(44.9%) occur in OAs, with 21,805(30.1%), 18,349(25.3%), 14,645(20.2%), and 17,647(24.4%) occurring in 60-64, 65-69, 70-74, and ≥75year age groups. The truncated incidence rates for OAs are 55

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… Including geriatric oncology as a separate subspecialty in the curriculum of all oncology training programs may increase awareness about the needs of OA cancer patients. …

Biologics and Non-Biologics Immunosuppressive Treatments for IgA Nephropathy in Both Adults and Children.

Immunoglobulin A nephropathy represents the most prevalent cause of glomerulonephritis worldwide and may lead to renal failure in a relevant number of cases in both paediatric and adult subjects. Although their pathogenesis is still largely unclear, evidence of immune abnormalities provides the background for the use of immunosuppressive drugs, such as corticosteroids, calcineurin inhibitors, and antiproliferative and alkylating agents. Unfortunately, these treatments fail to achieve a sustained remission in a significant percentage of affected patients and are burdened by significant toxiciti

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… IgA Nephropathy: Core Curriculum 2021. Am. J. Kidney Dis. 2021;78:429–441. doi: 10.1053/j.ajkd.2021.01.024. 8. Coppo R. Biomarkers and targeted new therapies for IgA nephropathy. Pediatr. Nephrol. 2017;32:725–731. doi: 10.1007/s00467-016-3390-9. 9. Gesualdo L., Di Leo V., Coppo R. …

Obesity Pillars roundtable: Excessive weight reduction with highly effective anti-obesity medications (heAOMs).

BackgroundHistorically, many anti-obesity medications (AOMs) were withdrawn from development and/or the market due to safety concerns. Another challenge was that, with some exceptions, most of these AOMs had limited weight reducing efficacy. Approved AOMs often did not meet the weight reduction expectations of either clinicians, or their patients. Currently, newer approved and investigational AOMs achieve greater weight reduction than older AOMs. This has prompted an emerging new challenge of "too much weight loss" with some of these highly effective anti-obesity medications (heAOM) - somethin

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… I am the Director of Obesity Medicine at OU where I founded the Obesity Medicine clinical curriculum. I work with students and residents across primary care. My research interests focus on the neurophysiologic effects of AOMs and new incretin therapies. Dr. Bays: Dr. …

The 48th Annual Meeting of the European Society for Blood and Marrow Transplantation: Nurses Group - Poster Sessions (NP001 - NP054).

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… At FiT survey, 95% of caregivers gave the highest score (in a scale of 1–5) and perceived very positive the experience for their professional curriculum vitae. On the other hand, eleven (76%) of the caregivers included in this collaboration agreement found a related work with the program. …

Ten Наводки на биопсию почек у больных раком.

Ренальная биопсия — это важный диагностический инструмент, который следует учитывать у больных раком, население которого часто страдает почечной дисфункцией, многофакторной и клинической активностью. Точное выявление основных повреждений часто имеет решающее значение для руководства онкологической терапией, предотвращения дальнейшего упадка почечной железы и улучшения общих результатов. Однако проведение биопсии в этой уязвимой группе пациентов требует тщательной оценки процедурных рисков и клинического контекста. Это...10 Брошюра < < Советы > > обеспечивает практическую основу для

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… Onco-nephrology: core curriculum 2015 . Am J Kidney Dis . 2015 ; 66 : 869 – 83 . 10.1053/j.ajkd.2015.04.042 26060184 PMC5479309 33. De A , Calcutta A , Della Pietra GP et al. Potential role of aliskiren in cancer modulation compared to other renin-angiotensin inhibitors: an in-depth review . …

Indications and recent evidence for apheresis in children and adults with kidney diseases: a comprehensive review.

IntroductionPlasmapheresis has been a therapeutic option in kidney diseases to eliminate disease-causing autoantibodies, circulating factors, and abnormal components involved in complement pathways. We aim to systematically review the effectiveness and adverse events associated with plasmapheresis and related apheresis therapies in treating kidney diseases in paediatric and adult populations.MethodsWe searched databases including EMBASE, CINAHL, PubMed, and Cochrane Central for studies from 2010 to October 2023. The search terms included terms related to glomerulonephritis treated with plasmap

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… Therapeutic plasma exchange: core curriculum 2023. Am J Kidney Dis 2023;81:475–92. 10.1053/j.ajkd.2022.10.017 12. Carter CE, Benador NM. Therapeutic plasma exchange for the treatment of pediatric renal diseases in 2013. Pediatr Nephrol 2014;29:35–50. 10.1007/s00467-013-2479-7 13. Goldstein SL. …

Timely integration of palliative care into oncology in hospitals in the Netherlands: a feasibility study.

BackgroundTimely integration of palliative care has numerous benefits for patients with incurable cancer. Based on a recent national Delphi study on the timely integration of palliative care in oncology, three recommendations were formulated regarding 1) advance care planning (ACP), 2) routine symptom monitoring during the last year of life, and 3) involving the Specialist Palliative Care Team (SPCT) during the last three months of life. This pilot study aimed to assess the feasibility of these recommendations in the Dutch context.MethodsFour Dutch hospitals implemented these recommendations f

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… At present, however, palliative care training is not integrated into medical education and clinicians are not required to undertake additional training, although steps are being taken to improve the curriculum [ 60 ]. …

Acute kidney injury in critically ill cancer patients: an update.

Patients with cancer represent a growing group among actual ICU admissions (up to 20 %). Due to their increased susceptibility to infectious and noninfectious complications related to the underlying cancer itself or its treatment, these patients frequently develop acute kidney injury (AKI). A wide variety of definitions for AKI are still used in the cancer literature, despite existing guidelines on definitions and staging of AKI. Alternative diagnostic investigations such as Cystatin C and urinary biomarkers are discussed briefly. This review summarizes the literature between 2010 and 2015 on

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… Onco-nephrology: core curriculum 2015. Am J Kidney Dis. 2015;66:869–83. doi: 10.1053/j.ajkd.2015.04.042. 3. Lameire N. Nephrotoxicity of recent anti-cancer agents. Clin Kidney J. 2014;7:11–22. doi: 10.1093/ckj/sft135. 4. …

Psychometric properties of the Chinese version of the M.D. Anderson symptom Inventory-Multiple Myeloma Module: a translation and validation study.

BACKGROUND: The reliability of the M.D. Anderson Symptom Inventory-Multiple Myeloma Module (MDASI-MM) was evaluated through its Chinese translation among Chinese patients with multiple myeloma. METHODS: The MDASI-MM scale underwent translation into Chinese following Brislin's two-way translation paradigm, incorporating ortho-translation, back-translation, pre-surveying, and cultural adaptation. The scale's validity and reliability were assessed using a sample of five hundred multiple myeloma patients from three tertiary general hospitals in Zhejiang Province, China, selected through convenien

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… The theoretical curriculum encompassed research contextualization and cross-cultural adaptation rationale, instrument structure and psychometric properties, standardized operating procedures for data acquisition, patient-centered communication strategies, quality control metrics, and ethical compliance …

Cardiotoxicity Induced by Anticancer Therapies: A Call for Integrated Cardio-Oncology Practice.

The introduction of novel oncologic therapies, including targeted agents, immunotherapies, and antibody-drug conjugates, has transformed the therapeutic landscape of cancer care. This evolution has resulted in a dual clinical scenario; while survival outcomes have markedly improved, leading to a growing population of long-term cancer survivors, an increasing incidence of previously unrecognized treatment-related toxicities has emerged. Among these, cardiovascular adverse events represent some of the most prevalent and clinically significant complications observed in both conventional chemother

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… To support this evolving field, the European Society of Cardiology has issued a Core Curriculum that outlines progressive levels of clinical competency, from observation to full autonomy, based on the CanMEDS framework. …

Применение телемедицины в лечении усталости пациентов с множественным склерозом: обзор аналитического исследования.

Усталость является распространенным симптомом у людей с множественным склерозом, однако доказательства эффективности телемедицины в лечении этого симптома остаются неполными. Несмотря на положительные результаты клинических испытаний, его учет в практической деятельности и систематическая оценка являются ограниченными. ЦЕЛЬ: Цель этого исследовательского проекта заключается в тщательной оценке того, насколько хорошо телемедицина помогает пациентам, страдающим от усталости. МЕТОДЫ: Этот аналитический обзор проводился в соответствии с методологической основой Института Джоанны Бриггс и с учетом

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… Integration of telehealth education into the health care provider curriculum: a review. Telemed J E Health. 2021;27(2):137–49. doi: 10.1089/tmj.2019.0261 …

The use of smart technologies for enhancing palliative care: A systematic review.

IntroductionWith the rapid advancement of technology, smart technologies have permeated various sectors, including palliative care in healthcare. Based on the available literature, similar studies have elucidated the application of individual and isolated smart technologies in palliative care, with their benefits, and limitations. This research, therefore, focuses on the conceptualisation of various smart technologies and makes holistic recommendations on the effective and efficient use of smart technologies in healthcare to enhance palliative care.PurposeThe purpose of this study is to system

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… Apps/websites have the potential to reduce unnecessary tests and costs for both patients and providers | There exists a necessity to modify the training curriculum to enhance the skill set of palliative care experts in providing care that capitalises on digital technologies. …