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The burden of childhood asthma.

Paediatric asthma is a major clinical concern worldwide and represents a huge burden on family and society. It accounts for a large number of lost school days and may deprive the child of both academic achievement and social interaction. Childhood asthma also places strain on healthcare resources as a result of doctor and hospital visits and the cost of treatment. The prevalence of asthma varies worldwide, possibly because of different exposure to respiratory infection, indoor and outdoor pollution, and diet. Certain risk factors appear to predispose children to developing asthma and atopic di…

Comprehensive sexual health centers: is it time?

Psychiatric epidemiologic research, mental health professionals, and nonpsychiatric physicians still largely avoid dealing with the problems of sexual identity and function. The Department of Psychiatry at Case Western Reserve University, in contrast to these trends, has established a Center for Human Sexuality, an innovative mental health center that employs full- and part-time staff to provide services, education, and research. The Center may serve as a model for other institutions that perceive the social, academic, and economic value of dealing with these high prevalence, underserved probl

The influence of seven environmental and physiological factors on duck plague virus shedding by carrier mallards.

Duck plague (DP) carrier mallards (Anas platyrhynchos) were subjected to seven environmental and physiological conditions in an attempt to stimulate DP virus shedding. The conditions were: food quality, social interaction, reproductive state, time dependency of food and water, noise, exercise, and sex of bird. Cloacal and oral swabs were taken daily for 10 days and assayed for DP virus content. The stimulated carrier ducks shed DP virus intermittently in amounts up to 10(8) ffus/swab/day (the highest 10-fold dilution still showing specific fluorescence). Unstimulated DP carrier ducks shed only…

Boosting or Blocking Breastfeeding Confidence? The Role of Online Breastfeeding Content in Relation to Mothers' Breastfeeding Self-Efficacy.

Mothers increasingly go online to find answers to their breastfeeding concerns, read personal experiences, or connect with breastfeeding "mommy influencers." This study analyzes how the consultation of online platforms and breastfeeding-related posts is linked to mothers' breastfeeding self-efficacy, and whether this relationship is moderated by mothers' different motives (i.e., information-seeking, entertainment, or community building) for consuming such content online within a Dutch-speaking context. Drawing on Social Cognitive Theory and the Uses and Gratifications framework, an online surv

Facilitators and Barriers for Participation in Physical Activity Among Norwegian Physically Active First-Year Students: A Qualitative Study.

Regular physical activity is essential for physical and mental health, yet participation among Norwegian university students remains below nationally recommended levels. This study explored facilitators and barriers for physical activity among first-year students, using the COM-B model as a conceptual framework. Fifteen physically active first-year students from two higher education campuses in Bodø were interviewed in spring 2025, and the data were analysed using inductive thematic analysis. Analysis showed that students' activity behaviours were shaped by a dynamic interaction between physic

Telemedicine in pediatric oncology during the COVID-19 pandemic: a cross-sectional questionnaire-based study evaluating the patient perspective.

The COVID-19 pandemic was a major driver for the integration of telemedicine in many different medical fields, but applications in pediatric … disadvantages were the lack of on-site physical examinations, absence of blood testing, and reduced social interaction with hospital staff, other patients, and their families. These findings suggest generally positive perceptions of telemedicine in pediatric oncology care, and indicate that a hybrid model combining remote and in-person visits could potentially addre …

Paternal fenvalerate exposure causes autism-like behavior partly by altering epigenetic reprogramming of the imprinted gene IGF2 in fetal brain and paternal sperm.

Fenvalerate, a representative type II pyrethroid insecticide, is well established in the literature. Fenvalerate exerts developmental and neurological toxicity. We assessed whether paternal fenvalerate exposure induces autism-like behavioral alterations in offspring using a mouse model. Behavioral tests, including the three-chamber social interaction, self-grooming, and marble-burying tests, showed altered social and repetitive behaviors in offspring from fenvalerate-exposed fathers. NeuN, a mature neuronal marker, was reduced in the medial prefrontal cortex (mPFC) of weaning offspring from pa…

Restoration of axon initial segment plasticity via chemogenetic activation rescues autism-related behaviors.

Autism spectrum disorder (ASD) presents a major clinical challenge, necessitating the identification of novel therapeutic targets rooted in … this targeted intervention normalized AIS structure and rescued core ASD-like behaviors, including social interaction deficits and repetitive behaviors. These results demonstrated that AIS alterations in this ASD model represent a reversible form of maladaptive plasticity, rather than permanent neuropathology. Our study highlights circuit-specific AIS modulation as …

Characterizing the associations between social determinants of health and functional recovery among pediatric inpatient rehabilitation traumatic brain injury patients.

OBJECTIVE: To examine differences in functional outcomes in the acute period following pediatric traumatic brain injury (TBI) as they relate to social determinants of health (SDoH). Setting: An inpatient rehabilitation program at a children's hospital in the Mountain West region of the United States. Participants: Eighty-nine patients with a diagnosis of moderate-to-severe TBI (ages 5-18 years old). DESIGN: Data were extracted from a clinical registry. Correlations and generalized linear regression were used to examine the relationships among injury characteristics, sociodemographic factors,

Post-divorce growth: a mixed-methods investigation of how post-traumatic stress shapes growth after divorce.

INTRODUCTION: This study aimed to examine the relationship between post-traumatic stress (PTS) and post-traumatic growth (PTG) after divorce among divorced individuals and to identify factors influencing growth through quantitative and qualitative findings. METHODS: A mixed-methods design was employed in two phases. In the first phase, data were collected from 489 participants using a Personal Information Form, the PTSD Checklist for DSM-5 (PCL-5), and the Posttraumatic Growth Inventory (PTGI). In the second phase, four groups were formed based on high and low scores, and qualitative data wer

Alleviating late-life depression with smart technology: Evidence from China.

Digital public policies are increasingly promoted as tools for supporting healthy aging, yet causal evidence on their mental-health conseque … ldercare policies improve mental well-being by lowering the transaction costs of service access and social interaction. Specifically, digital technologies appear to expand social participation by reducing participation barriers and to improve service accessibility by increasing the effective regional supply of eldercare services through data-driven platforms. The pr …

Religious activities, modern media use, and subjective wellbeing: a cultural goal consistency perspective.

INTRODUCTION: In digital societies with evolving pathways to subjective well-being, modern media has become a new channel for individuals to seek cultural interaction and identity recognition beyond traditional religious methods. However, how these two mechanisms relate to subjective well-being across cultural contexts remains insufficiently understood. METHODS: Using large-scale samples from the China General Social Survey and the European Social Survey, this study conducts regression analyses to examine the relationships among religious activities, modern media use, and subjective well-bein

Toward resolving normality-disorder boundary issues in gaming disorder research.

A longstanding challenge in the behavioral addictions field has been determining the point at which gaming involvement becomes clinically si … gaming as part of a routine, developing skills, changing mood or relieving boredom, or facilitating social interaction is not sufficient for a diagnosis; and that cultural and peer group norms should be considered in diagnosis. In this paper, we examine gaming normality-disorder boundary issues in the areas of conceptualization, assessment, and interventions. Some e …

An ALE meta-analysis of the neural evidence of facial emotion processing in autism.

OBJECTIVE: Facial emotion recognition is central to successful social interaction. People with autism spectrum disorder (ASD) have difficulties in this area. However, neuroimaging evidence on facial emotion processing in ASD has been diverse. This study aims to identify common and consistent brain activity patterns during facial emotion processing in autism. METHODS: Following PRISMA guidelines, 22 fMRI studies (539 ASD, 502 typically developing participants (TD) were included. RESULTS: Both groups showed significant activation in the right fusiform gyrus (FG) and left fusiform face area (FF…

Incident multimorbidity and associated factors among middle-aged and older adults in Thailand.

Assessing the longitudinal relationship between sociodemographic, lifestyle, and psychological characteristics and incident multimorbidity ( … estyles related to reducing bodyweight, screening and treatment of poor mental health and improving social interaction may reduce MM in Thailand.

How LGBTQ + adults' experiences of multiple disadvantage impact upon their health and social care service pathways in the UK & Ireland: a scoping review.

BACKGROUND: Despite increased awareness of the significant health and healthcare inequalities experienced by minoritised groups, limited research considers the interaction of multiple domains of social disadvantage. This review therefore sought to explore how LGBTQ + adults' experiences of homelessness, substance use, and criminal justice involvement impact upon their access to and use of health and social care services in the UK and Ireland. METHODS: A qualitative scoping review was conducted in accordance with the PRISMA-ScR framework. Electronic database and web searches identified 26 elig

A qualitative study of risk and resilience for positive life outcomes in neurodivergence using the WHO ICF.

Resilience is a dynamic process involving the interaction of multi-systemic individual and environmental factors that operate to protect against adversity and promote positive personal outcomes. Resilience is a topic of interest among groups who commonly experience adversity. Yet, it has received limited attention in the context of neurodivergence (e.g., autism and Attention Deficit Hyperactivity Disorder). This study is part of a larger project investigating the bio-psycho-social factors contributing to resilience in neurodivergence using the World Health Organization's International Classifi

Effects of environmental enrichment during adolescence on social defeat effects.

Social defeat (SD) is a well established model that increases addiction vulnerability accompanied by depressive- and anxiety-like behaviors. Environmental enrichment (EE) has been shown to enhance resilience and mitigate stress-induced behavioral alterations. Here, we investigated the protective effects of EE during adolescence, both before and during SD encounters, on stress-induced anxiety, depression and the increased conditioned rewarding effects of a subthreshold cocaine dose in adulthood. We employed the social interaction test (SIT) to categorize mice into resilient and susceptible phen…

Prevalence and Comorbidity of Dental Phobia in a Representative Population of 16-Year-Olds in Norway.

BACKGROUND: Although dental fear and anxiety are common in children and adolescents, they are not well-defined constructs and may not capture critical clinical aspects. Dental phobia (DP) is more well-defined as a specific phobia that includes the criteria of functional impairment. AIM: To investigate the prevalence and covariates of DP. DESIGN: A representative sample from two birth cohorts in Trondheim, Norway (n = 666) was assessed at age 16. A diagnostic interview using the Kiddie Schedule for Affective Disorders and Schizophrenia was conducted with both parent and adolescent. Personalit

Небольшие многочисленные проблемы склероза формируют трудовой опыт, влияют на самооценку и часто становятся банальными, несмотря на раскрытие информации.

ВВЕДЕНИЕ: Несмотря на незначительную инвалидность, лица с множественным склерозом часто сталкиваются с проблемами, связанными с работой, и с сокращением занятости. Их опыт, связанный с рабочими проблемами, недостаточно изучен. ЦЕЛЬ: Изучение проблем, связанных с работой, и возможностей обеспечения устойчивой занятости среди работающих лиц с легкой или умеренной инвалидностью. МАТЕРИАЛЫ И МЕТОДЫ: Углубленные интервью с 26 работающими сотрудниками PwMS, проанализированными с использованием систематической конденсации текстов, основанной на теориях Гоффмана о самосознании и социальном взаимодейст

Совпадение в аннотации оригинала
INTRODUCTION: Despite mild disability, people with multiple sclerosis (PwMS) often face work-related challenges and reduced employment. Thei … employed PwMS analyzed using systematic text condensation guided by Goffman's theories on self and social interaction. RESULTS: Three categories were developed: (1) unspoken work challenges, (2) the cumulative impact of mild MS symptoms on work challenges, and (3) disability and work challenges influence "who I am at work". Communication about work challenges was …