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In vitro anti-proliferative activities of Aloe perryi flowers extract on human liver, colon, breast, lung, prostate and epithelial cancer cell lines.

Natural products, especially plant extracts have offered vast opportunities in the field of drug development due to its chemical diversity. The genus Aloe has for long been used for medicinal purposes in different parts of the world. The present study was designed to investigate the phytochemicals and anti-cancer potential of Aloe perryi flowers. The phytochemical analysis revealed the presence of carbohydrates, glycosides, phytosterols, phenols, flavonoids and proteins. While alkaloids and saponins were absent. The percentage inhibition of various extracts (viz. petroleum ether, chloroform, e…

Investigations of the total flavonoids extracted from flowers of Abelmoschus manihot (L.) Medic against α-naphthylisothiocyanate-induced cholestatic liver injury in rats.

ETHNOPHARMACOLOGY RELEVANCE: The decoction of the flowers of Abelmoschus manihot (L.) Medic was traditionally used for the treatment of jaundice and various types of chronic and acute hepatitis in Anhui and Jiangsu Provinces of China for hundreds of years. Phytochemical studies have indicated that total flavonoids extracted from flowers of A. manihot (L.) Medic (TFA) were the major constituents of the flowers. Our previous studies have investigated the hepatoprotective effects of the TFA against carbon tetrachloride (CCl4) induced hepatocyte damage in vitro and liver injury in vivo. This study…

Antidiabetic activity of Pterospermum acerifolium flowers and glucose uptake potential of bioactive fraction in L6 muscle cell lines with its HPLC fingerprint.

The present study was designed to estimate the detailed antidiabetic activity of Pterospermum acerifolium (L.) Willd flowers. In vitro alpha amylase inhibition study was carried out on 50% ethanol extract of flowers (PAFEE) and its various fractions. The active ethyl acetate fraction (PAFEF) was subfractionated into three subfractions (PAFE1, PAFE2, and PAFE3) and subjected to acute toxicity studies followed by antidiabetic screening in vivo by streptozotocin-nicotinamide induced type II diabetes. Diabetic animals treated with PAFE2 (30 mg/kg) reduced the levels of fasting blood glucose, signi…

Cold tolerance and plant growth promotion potential of Serratia marcescens strain SRM (MTCC 8708) isolated from flowers of summer squash (Cucurbita pepo).

AIM: To determine the cold tolerance and plant growth promotion potential of Serratia marcescens strain SRM (MTCC 8708). METHODS AND RESULTS: Serratia marcescens strain SRM was isolated from the flowers of summer squash plants, showing no apparent symptoms of yellow vine disease. It was evaluated for growth and plant growth promotion attributes at 15 and 4 degrees C. At 15 degrees C, the isolate was able to solubilize 76.6 microg ml(-1) of P and produce Indole Acetic Acid, IAA (11.1 microg ml(-1)). HCN and siderophore production were also detected at 15 degrees C. The isolate retained all the…

Indigenous knowledge and modern science: a comprehensive review of phytochemicals in Panax ginseng flower for nutritional and health applications.

Panax ginseng flowers, an annually renewable yet underutilized byproduct of ginseng cultivation, represent a promising raw material for functional foods that bridges traditional East Asian ethnobotanical practices with modern nutritional science. This review systematically summarizes the phytochemical constituents and pharmacological activities of ginseng flowers to evaluate their potential as health-oriented food ingredients. Published studies from recent decades were collected and analyzed. The major bioactive compounds identified include dammarane-type ginsenosides (protopanaxadiol and prot…

CRISPR/Cas9-mediated dual editing of VviGAI and VviFLC generates a novel early-flowering grapevine germplasm.

CRISPR/Cas9-mediated dual knockout of VviGAI1 and VviFLC in grapevine promotes early flowering and induces distinctive morphological changes, offering novel genetic resources for breeding. CRISPR/Cas9-mediated genome editing offers a transformative approach for grapevine improvement. In this study, we achieved simultaneous knockout of two central flowering regulators VviGAI1, a DELLA protein ortholog, and VviFLC, a floral repressor in Vitis vinifera 'Cabernet Sauvignon' using a dual-sgRNA vector system. Remarkably, all 15 independent edited lines exhibited biallelic mutations in both genes, pr

Genome-Wide Characterization of PEBP, FD, and GRF Families in Amomum villosum Lour. and Their Potential Roles in Flowering.

A detailed understanding of the molecular mechanisms governing the flowering time of Amomum villosum Lour., a medicinal plant within the Zingiberaceae family, is currently lacking. In modern plants, the florigen activation complex (FAC), which includes PEBP, FD/bZIP, and GRF proteins, is known to regulate flowering. In this study, we identified 13 PEBP, 5 FD, and 19 GRF genes within the A. villosum genome and conducted phylogenetic, structural and promoter analysis. Notably, cross-species protein-protein interaction predictions and yeast two-hybrid assays uncovered an unexpected interaction pa

Human m6A demethylase FTO modulates the flowering time of tomato plants under low-temperature stress.

N6-methyladenosine (m6A) RNA modification plays an important role in plant development and environmental stress responses. However, whether m6A demethylation modulates flowering under low-temperature (LT) stress in tomatoes remains unclear. Here, we investigated whether ectopic expression of FTO, a well-characterized human m6A demethylase, influences flowering and post-transcriptional behaviour in tomato (Solanum lycopersicum) under LT conditions. Flowering of transgenic tomato plants expressing FTO was analyzed under LT and normal conditions (NC), and the impacts of FTO on transcripts-specifi

Chloroplast genome sequence of the hybrid variety 'Silky White', a white-flowered calla lily (Zantedeschia aethiopica).

Calla lily (Zantedeschia spp.), native to southern Africa, is a very attractive plant and is used as cut flowers, potted flowering plants, and bedding plants. It can be distinguished into two groups depending on the color of the flower. The chloroplast genome of the hybrid variety 'Silky White' (Z. aethiopica × Z. aethiopica), a white-flowered calla lily, was sequenced using Illumina sequencing technology. The total length of the chloroplast genome was 168,880 bp with a GC content of 35.59%. It comprised a large single copy (LSC) region of 89,391 bp, a small single copy (SSC) region of 31,849 …

Rewiring the SVP-AGL24 module into a flowering-promoting cascade via legume-specific E1 repressors in soybean.

Photoperiodic flowering is a critical determinant of soybean regional adaptation and yield, and is predominantly governed by the legume-specific E1 repressor family. How evolutionarily conserved MADS-box transcription regulators such as AGAMOUS-LIKE 24 (AGL24) and SHORT VEGETATIVE PHASE (SVP) integrate into the E1 module remains unclear. Here, we show that soybean GmSVP1 and GmSVP2 promote flowering under long-day conditions. GmSVP1/2 directly bind to and repress the E1 family genes, and genetic analyses demonstrate that this repression accounts for the flowering-promoting activity of endogeno

A flower-shaped dual-band four port MIMO antenna with novel DGS for 5G mmWave applications.

A novel quad-port multiple-input multiple-output (MIMO) antenna with enhanced isolation is proposed by incorporating a specifically designed hybrid defected ground structure (DGS) for dual band 5G mmWave wireless applications. This suggested MIMO antenna system features a distinctive DGS, consisting of a central circular slot combined with four surrounding trapezoidal cut-outs at the base of the ground plane for enhanced isolation and comprises four identical elliptical monopole elements. Initially, a four-element MIMO system is developed to achieve optimal performance. Subsequently, the conFi

Integrated Proteomics and Metabolomics Analysis Reveals Regulatory Mechanisms Underlying Flower Bud Development in Camellia drupifera.

Camellia drupifera is an economically important woody oil plant rich in edible seed oil. High-quality and well-developed floral buds are key determinants of its yield. However, studies on the regulatory mechanisms underlying its floral bud development remain relatively limited. In this study, proteomics and metabolomics profiles, along with physiological traits, tested during the final three developmental stages of floral buds. The results showed that the contents of indole-3-acetic acid (IAA), abscisic acid (ABA), and 1-aminocyclopropane-1-carboxylic acid (ACC, a precursor of ethylene) decrea

Pink lotus flower (Nelumbo nucifera) oil extract alleviates imiquimod-induced psoriasis-like dermatitis.

Pink lotus (Nelumbo nucifera Gaertn.) contains bioactive flavonoids and alkaloids that exert anti-inflammatory and antioxidant activities, and inhibit TNF-α, IL-1β, IL-6 and NF-κB signaling pathways implicated in the pathogenesis of psoriasis. However, the effects of pink lotus flower oil (PLO) on psoriasis-like skin inflammation remain unexplored. Therefore, the present study aimed to evaluate the effects of PLO treatment on imiquimod (IMQ)-induced psoriasis-like skin inflammation in a mouse model. Briefly, BALB/c mice with IMQ-induced psoriasis were administered PLO (100 and 200 mg/kg), and

Допуск на засуху в хлопковых генотипах с помощью интегрированных морфофизиологических и биохимических маркеров на стадии цветения.

Засушливый стресс one из основных абиотических факторов, которые серьезно ограничивают глобальный урожай хлопка, нарушая основные морфофизиологические и биохимические функции. В этом исследовании forty В разделе, посвященном генетически разнообразным генотипам хлопка, была проведена оценка three ирригационные уровни: контроль100% мощность на местах), умеренная (60% FC) и сильная засуха40% FC) на стадии цветения в контролируемой стеклянной среде. Повышение интенсивности засухи привело к постепенному снижению темпов роста и физиологических характеристик. Острый стресс: уменьшение длины выстрела

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… Regular irrigation with tap water continued until the onset of flowering. … FR was monitored every 8–10 days until boll development, and at 25 days post-anthesis, the number of retained flowers was recorded. Flower retention percentages were computed by using the protocol established by 7 . …

ZFD-Net: Zinc flower defect detection model of galvanized steel surface based on improved YOLOV5.

Due to the complex factory environment, zinc flower defects and galvanized sheet background are difficult to distinguish, and the production line running speed is fast, the existing detection methods are difficult to meet the needs of real-time detection in terms of accuracy and speed. We propose ZFD-Net, a zinc flower defect detection model on the surface of galvanized sheet based on improved you only look once (YOLO)v5. Firstly, the model combined the YOLOV5 model with our proposed cross stage partial transformer (CSTR) module in this paper to increase the model receptive field and improve t

Impacts of elevated temperature and CO2 concentration on carbon metabolism in an endangered carnation: Consequences for biomass allocation and flowering.

One of the greatest threats to plant function and fitness is global warming, characterised by a combination of increased atmospheric CO2 concentrations and temperatures. However, their effects on plant physiology, growth, and reproduction remain unclear, particularly for rare species that support vulnerable ecosystem functions. Here, we investigated these effects on leaf and whole-plant functional traits of the rare endangered C3 species Dianthus inoxianus. Mature plants were grown for 18 weeks in controlled-environment chambers under four environmental scenarios that combined day/night air te

A Wearable Acetone Gas Sensor Enabled by Quantum Dot-Sensitized Flower-like Ti3C2Tx for Metabolic Monitoring.

Acetone, a key biomarker for metabolic processes, and its excessive levels can cause ketosis or even ketoacidosis, posing significant risks to human health. Therefore, real-time acetone detection is crucial for noninvasive health monitoring. Ti3C2Tx-based sensors demonstrated considerable potential for detecting VOC gases but often face issues with sensitivity and environmental stability. In this work, a flower-like Ti3C2Tx anchored with MoS2 quantum dots (F-Ti3C2Tx/MoS2) was proposed for the first time to achieve accurate acetone detection even under high humidity conditions. The unique flowe

A facile synthesis of silver nanoparticles using Woodfordia fruticosa flower extracts for certain bacteria inhibition applications.

The present research focused on extraction of bioactive compounds from Woodfordia fruticosa flower (WF) using ethanol, methanol and ethyl acetate as solvents and the development of silver nanoparticles using these extracts for inhibition of Staphylococcus aureus (S. aureus), Klebsiella pneumoniae (K. pneumoniae), Escherichia coli (E. coli), and Bacillus cereus (B. cereus) bacteria. The functional groups of bioactive compounds present in the solvent extracts were characterized using Fourier transform infrared spectroscopy (FT-IR). The morphological features and formation of silver nanoparticles

Carbon monoxide promotes flowering in Lemna gibba via a nitric oxide-dependent oxidative stress pathway.

Carbon monoxide promotes flowering in Lemna gibba via a nitric oxide-dependent oxidative stress pathway involving a CO → NO → ROS signaling cascade. This novel redox-regulated mechanism offers new insights into floral transition, which is distinct from conventional photoperiod-dependent pathways. Carbon monoxide is increasingly recognized as a signaling molecule in plant systems; however, its role in reproductive development remains poorly understood. This study showed that carbon monoxide promotes flowering in Lemna gibba through a novel pathway involving nitric oxide and reactive oxygen spec