Результаты поиска

[Efficiency of portable sleep apnea screening instruments].

Diagnosis of a sleep apnoea syndrome in severely snoring patients with diurnal sleepiness is growing in importance in the consulting rooms of general practitioners, internists, ENT specialists and pneumologists. However, time and cost reasons limit the diagnostic procedures conducted by practitioners to outpatient screening. Two different systems are presently available in Germany. The MESAM system (Madaus, Freiburg) records by means of a microphone and various electrodes the oxygen saturation, heart rate, snoring and sleeping position of the patient. The Apnoe-Check System (Medanz, Starnberg)

[Nocturnal hypoxia--its relevance with reference to sleep structure in patients with coronary heart disease].

A disorder in the physiological structure of the sleep cycles (macrostructure) is known to occur both in patients with sleep apnoea (SA) and coronary heart disease (CHD). The study presented here was concerned with the problem whether the sleep structure in patients suffering from CHD and apnoea-conditioned hypoxia is greatly disturbed e.g. by myocardial ischaemia. Polysomnographic recordings including EEG, EOG, EMG and 6-channel ECG were performed for 6 nights in 30 patients suffering from sleep apnoea (AI > 10/h) and/without CHD. The average age of the patients was 57.9 years (range 47-68 yr

Menstrual-associated sleep disorder: an unusual hypersomniac variant associated with both menstruation and amenorrhea with a possible link to prolactin and metoclopramide.

A 42-year-old female presented with a history of hypersomnia associated with her menstrual periods. The menstrual periods abated coincident with the use of metoclopramide. The hypersomnolence, however, did not abate, but rather became more brief and erratic in its periodicity. The hypersomnolence was associated with marked elevations in the serum prolactin level.

[A case of central alveolar hypoventilation syndrome associated with cerebral infarction].

Central alveolar hypoventilation syndrome (CAH), or Ondine's curse, is a very rare disease characterized by dysfunction of respiratory center in the brain stem. Here, we report a case of CAH associated with cerebral infarction. A 59-year-old man developed right facial sensory deficit at age 56. Then, the facial sensory deficit spread to the left side and dysarthria and dysphagia also developed. Since age 58, he often developed respiratory failure and consciousness disturbance. Arterial blood gas analysis revealed alveolar hypoventilation and respiratory acidosis. Disorders of peripheral organs

Neuroendocrine and cardiovascular effects of MDE in healthy volunteers.

The drug 3,4-methylenedioxyethamphetamine ([MDE] also known as "Eve") is a less toxic analog of 3,4-methylenedioxymethamphetamine (also known as "Ecstasy") with similar psychotropic effects in humans. In a double-blind placebo-controlled, cross-over study we administered 140 mg of MDE or placebo orally to eight healthy male volunteers at 1:30 P.M. Serum cortisol, prolactin (PRL), and growth hormone (GH) levels, as well as blood pressure, and heart rate were measured every 20 minutes until 5:00 P.M. Administration of MDE was followed by statistically significant long-lasting increases of serum

Role of Cone-Beam Computed Tomography (CBCT) in Obstructive Sleep Apnea (OSA): A Comprehensive Review.

Obstructive sleep apnea (OSA) is characterized by recurrent partial or complete upper airway collapse during sleep. Accurate assessment of airway anatomy is crucial for risk stratification, diagnosis, and treatment planning. While polysomnography (PSG) is considered the gold standard for OSA diagnosis, it provides limited anatomical insights. Cone-beam computed tomography (CBCT) has emerged as a valuable tool with lower radiation dose for three-dimensional (3D) assessment of the upper airway space and craniofacial structures. CBCT enables precise measurement of critical airway parameters inclu…

Brain cholinergic imaging in isolated REM sleep behavior disorder: Distinctions and similarities with Parkinson's disease.

BACKGROUND: Isolated rapid eye movement sleep behavior disorder (iRBD) is a prodromal stage of α-synucleinopathy such as Parkinson's disease … findings with both healthy controls and patients with PD. METHODS: Forty-six participants (16 with polysomnography-confirmed iRBD, 12 with PD, and 18 controls) underwent high-resolution PET neuroimaging with FEOBV. Voxel-wise analyses and effect size mapping were conducted to compare the groups, using standardized uptake value ratios (SUVRs). Correlations were p …

Western University Protocol for Obstructive Sleep Apnea.

Background/Objectives: Obstructive sleep apnea (OSA) is a prevalent disorder in adults, characterized by recurrent upper airway obstruction … BMI and the STOP-BANG and Epworth Sleepiness scales, while postoperative care emphasizes follow-up polysomnography and adjunctive therapies only when necessary. Regional experiences in Saudi Arabia and Canada underscore the importance of standardized evidence-based surgical care. Conclusions: The purpose of this article is to establish a clear protocol for manag …

High prevalence of obstructive sleep apnea in patients with Long-COVID.

BACKGROUND: Long-COVID (LC) is defined as the persistence of symptoms 12 weeks after the acute COVID infection not explained by any other al … including standardized questionnaires to evaluate persistent symptoms, lung function tests and full polysomnography. RESULTS: We studied 73 patients with LC. Their mean age was 57.4 ± 10.5 years, they were predominantly male (56.2%), 73.9% of whom were hospitalized during the acute COVID episode. Median AHI was 17.2 (24.14) events/h with a proportion of mild (27 …

Electromyography Frequency Spectrum Is a Better Indicator of Sleep Bruxism Severity Related to Temporomandibular Disorder Pain Than Conventional Masticatory Muscle Activation and Bruxism Time Indices-A Pilot Study.

Sleep bruxism (SB) has been reportedly associated with temporomandibular disorder (TMD); however, solid evidence is lacking. Previous studie … ain compared to those without TMD pain. In this exploratory study, we retrospectively analysed home polysomnography data from 44 participants who indicated possible SB. The median signal frequencies and absolute power were calculated using the Fast Fourier Transform of the EMG signals during MMA events. Moreover, the MMA index and BTI were calculated, and all par …

Severe obstructive sleep apnoea can be accurately diagnosed in primary care centres.

We aimed to assess an obstructive sleep apnoea (OSA) diagnostic approach performed solely in primary care centres (PCC) with the support of an autoscoring home sleep apnoea testing (aHSAT, ApneaLinkTM Air) device and compare the diagnoses with those undertaken by the manual analysis of home sleep apnoea testing (mHSAT), and polysomnography (PSG) if necessary, of a certified sleep specialist. This multicentre, cross-sectional study was undertaken between April 2016 and November 2020. We randomly selected patients aged 30-70 years with a high probability of OSA (≥ 3 points on the STOP-Bang quest…

Paranasal Sinus CT and Polysomnographic Findings in Adults with Cystic Fibrosis: Implications for Obstructive Sleep Apnea.

OBJECTIVE: To assess whether chronic rhinosinusitis (CRS) severity is associated with obstructive sleep apnea (OSA) in adult people with cystic fibrosis (pwCF). METHODS: We conducted a retrospective single-center study of 44 adults with CF who underwent overnight polysomnography (PSG), Epworth Sleepiness Scale (ESS) assessment, and sinus computed tomography (CT). CRS severity was quantified using the Lund-Mackay score (LMS) and the main nasal cavity score (MNCS). OSA was defined by Apnea-Hypopnea Index (AHI) thresholds per American Academy of Sleep Medicine criteria. RESULTS: Participants ha…

The impact of paediatric periodic limb movement disorder and obstructive sleep apnoea syndrome on sleep quality and daytime symptoms.

PURPOSE: There is little available literature comparing paediatric periodic limb movement disorder (PLMD) and paediatric obstructive sleep apnoea syndrome (OSA). This retrospective study aimed to examine the impact of PLMD, OSA and OSA with an elevated periodic limb movement index (PLMI) on sleep quality and daytime symptoms. METHODS: This retrospective study examined 132 children who had been diagnosed with OSA (with or without elevated PLMI) and PLMD. All participants underwent overnight polysomnography. Patients were divided into three groups, patients with OSA with low PLMI, patients with…

Tonsil surgery is an effective treatment for pediatric obstructive sleep apnea irrespective of underlying comorbidities.

OBJECTIVE: To evaluate the effectiveness of tonsil surgery in managing obstructive sleep apnea (OSA) in children with comorbidities predisposing to OSA. METHODS: Children under 16 years of age with comorbidities who underwent tonsil surgery for OSA and had both pre- and postoperative polysomnography (PSG) within two years of surgery at Helsinki University Hospital, Finland, between 2009 and 2024 were retrospectively reviewed. RESULTS: The study comprised 33 children, of whom 26 (79%) underwent (adeno)tonsillotomy and 7 (21%) (adeno)tonsillectomy. All participants had medical comorbidities, s…

[Analysis of CBCT-based soft tissue predictors for obstructive sleep apnea in adults].

Objective:To investigate the relationship between soft tissue measurements from cone beam computed tomography（CBCT） imaging obtained for dental treatment purposes and the severity of obstructive sleep apnea（OSA） in adults, and to evaluate the value of these soft tissue variables as alternative predictors for OSA screening. Methods:A total of 140 subjects with snoring were enrolled retrospectively based on polysomnography and CBCT examinations. Participants were categorized into a primary snoring group and an OSA group based on the apnea-hypopnea index. Upper airway soft tissue parameters were …

Impaired sleep microarchitecture is associated with locus coeruleus degeneration in Parkinson's disease.

STUDY OBJECTIVES: Sleep disorders are common non-motor symptoms of Parkinson's disease (PD) that significantly impact patients' quality of life. Specifically, alterations in sleep microstructure - such as reduced slow-wave activity and sleep spindles - are prevalent in PD. The locus coeruleus (LC), the brain's primary source of noradrenaline, plays a pivotal role in regulating sleep and wakefulness and is highly vulnerable to neurodegeneration in PD. This study explores whether disruptions in sleep microarchitecture in PD are linked to LC degeneration. METHODS: We assessed polysomnography for…

Автосоматический синдром снотворного синдрома спящей апноэ из-за нового варианта c.980_984dup в COL1A2: A Case Report.

Осложненный синдром апноэ (OSAS) — сложное расстройство, характеризующееся коллапсом верхних дыхательных путей во время сна. Хотя история семьи часто свидетельствует о наследственной предрасположенности к ОСУС, нет никаких доказательств того, что это на самом деле моногенное расстройство. До настоящего времени не было описано ни одного случая, когда пациент с наследственным OSA из-за патогенной мутации в цепи коллагенов типа I альфа-2 (COL1A2). Пациенткой была 72-летняя женщина, которая страдала бессонницей с 35 лет. С тех пор ОСУС подозревалось, но было подтверждено только в возрасте 67 лет п

Совпадение в аннотации оригинала
Obstructive sleep apnea syndrome (OSAS) is a complex disorder characterized by the collapse of the upper airway during sleep. Although a fam … mnia since the age of 35. OSAS was suspected since then, but was only confirmed at the age of 67 by polysomnography. The OSAS was treated with nocturnal active positive airway pressure (APAP), which led to an improvement. Her medical history also included joint hypermobility, brachydactyly, multiple nevi, an umbilical hernia, left-sided tinnitus and hearing impai …

Response to noninvasive home mechanical vEntilation in Myotonic Dystrophy type 1: The multicenter REMeDY study.

Myotonic dystrophy type 1 (DM1) frequently leads to chronic respiratory failure, yet the effectiveness of noninvasive home mechanical ventilation (HMV) remains understudied. Our objective was to assess the effects of HMV on gas exchange, health-related quality of life (HRQL), and daily functioning, and to explore baseline predictors of treatment response. A prospective multicenter study was conducted in which clinical data, pulmonary function tests, blood gas analysis, polysomnography and overnight pulse oximetry with transcutaneous CO2 monitoring, and validated questionnaires were collected a…

Prevalence of pulmonary hypertension in children with Prader-Willi Syndrome.

RATIONALE: Prader-Willi Syndrome (PWS) is associated with obesity and sleep-related breathing disorders (SRBD). Pulmonary hypertension (PH) is prevalent in children with SRBD. We sought to determine the PH prevalence in children with PWS and SRBDs and determine the association of PH with OSA severity and obesity. METHODS: A retrospective study of patients with PWS followed at Children's Hospital Los Angeles was performed. Data collected included demographics, body mass index (BMI), echocardiogram, cardiac catheterization (if present), and polysomnography (PSG) results. RESULTS: 37 patients w…