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Поддержка со стороны сверстников в хронических условиях с точки зрения сверстников: систематический обзор.

Цель: Поддержка со стороны сверстников может стать ценным дополнением к обычному уходу за пациентами с хроническими заболеваниями. Хотя выгоды, связанные с поддержкой со стороны сверстников, хорошо задокументированы, в большинстве исследований основное внимание уделяется интересам получателей помощи. Учитывая центральную роль, которую играют сторонники из числа сверстников, их опыт следует рассматривать как не менее важный. В рамках этого систематического обзора обобщается имеющаяся литература, посвященная опыту сочувствующих друг другу лиц с хроническими заболеваниями. Метод: Мы проводили сис

Nurse Coaching in Oncology Care to Reduce Stress: A Systematic Review and Meta-Analysis.

Background: Nurse coaching can reduce stress throughout the complex psychosocial process associated with the cancer journey, which affects numerous spheres, such as neurological, psychological, physical, and emotional ones. The purpose of this paper is to review the literature to assess the extent of stress reduction among cancer care adopting nurse coaching interventions. Methods: This systematic review and meta-analysis was registered in PROSPERO with id no. CRD420261290368 and performed according to the Preferred Reporting Items for Systematic Reviews and Meta-analysis (PRISMA) guidelines.

Доступ к терапии перенаправления T-Cell в Мультимиломе: пациент, сторож и физиологическая точка зрения на осведомленность и барьеры.

Справочная информация: Лечение перенаправления Т-клеток (TCRTs), включая терапию CAR-T-клеток и биконкретные антитела, изменило методы лечения повторной/охлажденной множественной миеломы (MM), однако реальное усыновление по-прежнему ограничено из-за ограничений в плане осведомленности и доступа пациентов, лиц, обеспечивающих уход, и врачей. Методы: Мы провели перекрестное исследование (июнь-сентябрь) 2025) с использованием одобренных IRB обследований СВОД, распространяемых среди пациентов, имеющих MM (через MyChart), лиц, обеспечивающих уход за получателями ТСПР (по электронной почте) и общинн

Применение MR Pinger для печати позволило получить значения T1 и T2 в мозге взрослых: системный обзор.

ВВЕДЕНИЕ: Магнитная резонансная съемка (MRI) имеет важное значение для изображений мозга, однако традиционные методы основаны на качественном контрасте, являются трудоемкими и подвержены колебаниям. Магнитный резонансный отпечаток пальцев (MRF) устраняет эти ограничения, позволяя быстро и одновременно картировать свойства многочисленных тканей, таких как T1, T2. Используя динамические параметры приобретения и предварительно составленный словарь сигналов, МРФ обеспечивает надежные качественные карты, повышая диагностическую точность и расширяя применение клинических и исследовательских технолог

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… Men showed significantly higher T1 values in the left temporal WM, bilateral cerebellar hemispheres, and pons compared to women (p<0.05). For T2 relaxometry, a significant difference was found in the right lentiform nucleus between sexes (p<0.05). … Sex differences revealed higher relaxation times in men for frontal and parietal WM, reflecting potential neurodegenerative susceptibility, while relaxometry of temporal regions, cerebellum, and pons were influenced by sex dimorphism. …

Требования пользователей к количественным радиологическим отчётам при множественном склерозе.

ЦЕЛИ: Количественные радиологические отчеты (Q Reports) могут способствовать совершенствованию клинического управления множественным склерозом (MS) путем включения количественных данных, полученных в ходе сканирования МРТ. Однако отсутствие консенсуса в отношении конкретной информации для включения в нее данных о предпочтениях и предпочтениях врачей препятствует внедрению этих инструментов анализа изображений. Цель этого исследования состоит в том, чтобы облегчить клиническое внедрение QReports путем определения требований врачей в отношении их использования в управлении НР. МАТЕРИАЛЫ И МЕТОДЫ

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OBJECTIVES: Quantitative radiological reports (QReports) can enhance clinical management of multiple sclerosis (MS) by including quantitativ … was circulated following a plenary discussion at the MAGNIMS workshop in Milan in November 2023. Responses from both questionnaire iterations were collected and analyzed, with adjustments made based on participant feedback. RESULTS: The study achieved a 49.6% response rate, involving 78 respondents. Key preferences and barriers to QReport adoption wer …

Получил от "Puff of Domoke"-A Case-Review on the Challenging Discrimination of CNS Demielining Beace and Moyamoya Angiopatia.

Moyamoya aнгиопатия (MMA) — цереброваскулярное заболевание, определяющее хроническое прогрессивное включение надклиноидных внутренних артерий сонной артерии и их основных веток. Патогенез ММА по-прежнему в значительной степени неизвестен. Множественный склероз (MS) является хроническим, подстрекательским и демиелинизирующим заболеванием центральной нервной системы, характеризующимся постепенным накоплением фокусных демиелионирующих повреждений, патофизиология которых была теоретической, но до сих пор не до конца понята. Помимо неправильной диагностики из-за имитирующих эти два расстройства осо

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… The multifocal cerebral lesions as well as the MMA neuroimaging features were stable, except for the area in the left dorsal pons that showed a decreased hyperintensity on T2-weighted images. Whole exome sequencing was performed, and the following variants were identified ( Table 1 ). … MMA + MS Ischemic stroke (during steroid administration) Aspirin + Clopidogrel; bilateral bypass surgery High dose i.v. methylprednisolone 3 month [ 9 ] US/ Caucasian 57/F Episodic gait dysfunction; feet paresthesias; myelopathic signs Cervical and thoracic spinal cord; bilateral frontal lobes; right pons …

Sexual Function in Women Survivors of Hematologic Malignancy after Autologous Hematopoietic Stem Cell Transplantation.

A multicenter, cross-sectional study was conducted to assess the sexual function of women survivors of hematologic malignancy after autologous hematopoietic stem cell transplantation (AHSCT), and to compare it with that of healthy women controls. Fifty-six sexually active women survivors of hematologic malignancy who underwent AHSCT were recruited through convenience sampling, as well as 60 healthy women. Demographic and clinical data questionnaires and the Female Sexual Function Index (FSFI) were completed. Survivors had a median age of 44 years and a median time since transplant of 3 years,

Perceptions and Experiences of Hematopoietic Cell Transplantation Patients During the COVID-19 Pandemic.

ObjectivesSince March 2020, the severe acute respiratory syndrome coronavirus-2 pandemic has affected the global community, but poses unique challenges for individuals with cancer. Patients diagnosed with hematologic malignancies undergo aggressive therapies followed by hematopoietic cell transplantation (HCT) as a potential curative treatment. HCT recipients can be immunocompromised for extended periods of time, and even pre-pandemic, transplant patients reported depression and anxiety due to restrictions and infection prevention measures they had to adhere to as part of transplant precaution

Internet-based guided self-help for glioma patients with depressive symptoms: design of a randomized controlled trial.

BackgroundAmong glioma patients, depression is estimated to be more prevalent than in both the general population and the cancer patient population. This can have negative consequences for both patients and their primary informal caregivers (e.g., a spouse, family member or close friend). At present, there is no evidence from randomized controlled trials for the effectiveness of psychological treatment for depression in glioma patients. Furthermore, the possibility of delivering mental health care through the internet has not yet been explored in this population. Therefore, a randomized contro

Haemato-oncology and burnout: an Italian survey.

This cross-sectional survey aimed to evaluate the prevalence of burnout and estimated psychiatric disorders among haemato-oncology healthcare professionals in Italy. The aspects of work that respondents perceive as stressful and satisfying have also been examined. The assessments were made using the Maslach Burnout Inventory (MBI), General Health Questionnaire and a study-specific questionnaire. Logistic regression models were applied to show associations between different sources of work-related stress and burnout. Three hundred and eighty-seven out of 440 (87.95%) returned their questionnair

Распространение истерики у людей с множественным склерозом.

Аннотация не предоставлена источником. Откройте карточку для перехода к публикации.

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… Male 58 49 6 Left lower limb Weakness RRMS Interferon beta 1-a 1.5 Hypertension Ischemic Medulla 7 Female 49 21 10 Lower limbs paresthesia + diplopia RRMS Dimethyl fumarate 1 - Ischemic Left middle cerebral artery branch 8 Female 55 45 9 Upper limbs paresthesia RRMS Teriflunomide 1.5 - Hemorrhagic Pons …

Associations of Age and Sex with the Efficacy of Inpatient Cancer Rehabilitation: Results from a Longitudinal Observational Study Using Electronic Patient-Reported Outcomes.

Cancer rehabilitation is thought to increase the quality of life (QOL) and functioning of cancer survivors. It remains, however, uncertain whether subgroups benefit equally from rehabilitation. We wished to investigate the outcomes of multimodal rehabilitation according to age, sex and functioning. Patients of an Austrian rehabilitation center routinely completed the EORTC QLQ-C30 and the hospital anxiety and depression scale (HADS) questionnaires prior to (T1), and after rehabilitation (T2). To compare the outcomes between age groups (i.e., p p d. In conclusion, QOL is improved by rehabilitat

Investigating the therapeutic efficacy of psilocybin in advanced cancer patients: A comprehensive review and meta-analysis.

BackgroundPsilocybin, a naturally occurring psychedelic compound found in certain species of mushrooms, is known for its effects on anxiety and depression. It has recently gained increasing interest for its potential therapeutic effects, particularly in patients with advanced cancer. This systematic review and meta-analysis aim to evaluate the effects of psilocybin on adult patients with advanced cancer.AimTo investigate the therapeutic effect of psilocybin in patients with advanced cancer.MethodsA comprehensive search of electronic databases was conducted in PubMed, Cochrane Central Register

Pre-transplant depression decreased overall survival of patients receiving allogeneic hematopoietic stem cell transplantation: a nationwide cohort study.

Studies investigating association of depression with overall survival (OS) after allogeneic hematopoietic stem cell transplantation (allo-HSCT) yielded conflicting results. A nationwide cohort study, which included all adult patients [n = 7,170; depression group, 13.3% (N = 956); non-depression group, 86.7% (N = 6,214)] who received allo-HSCT from 2002 to 2018 in South Korea, analyzed risk of pre-transplant depression in OS of allo-HSCT. Subjects were followed from the day they received allo-HSCT, to occurrence of death, or last follow-up day (December 31, 2018). Median age at allo-HSCT for de

Effects of Physical Exercise Intervention on Psychological and Physical Fitness in Lymphoma Patients.

Background and objectives: Lymphoma patients experience a psychological and physiological decline that could be reversed by exercise. However, little is known about the effects of the exercise on psychological and physical fitness variables. Therefore, the purpose of this longitudinal study was to assess self-efficacy, fatigue and physical fitness before and after an eight-week exercise intervention. Materials and Methods: Thirty-six participants (54.4 ± 19.1 years) performed a supervised exercise program (~60 min, 2d·wk-1). Each session included a combined progressive training of cardiorespir

Gender Difference in Symptom Presentations Among Patients With Bone Metastases in Gender-Specific and Gender-Neutral Primary Cancers.

BackgroundStudies have assessed gender differences on symptoms commonly experienced by cancer patients at various stages in their disease trajectory using heterogeneous cancer populations with different tumor types. The purpose of our study was to evaluate the effect of gender on symptoms among patients with bone metastases while controlling for gender-specific malignancies.MethodsA retrospective review of patients receiving palliative radiotherapy for bone metastases was conducted on patients that completed the Brief Pain Inventory (BPI) or Edmonton Symptom Assessment System (ESAS) questionna

Physical and mental health of breast cancer patients and survivors before and during successive SARS-CoV-2-infection waves.

PurposeDuring the first SARS-CoV-2-infection wave, a deterioration in emotional well-being and increased need for mental health care were ob … questionnaires. Pre-COVID-19 EORTC-QLQ-C30/BR23 and HADS outcomes were available from UMBRELLA. Response rates were 69.3% (n = 1106/1595) during the first SARS-CoV-2-infection wave and 50.9% (n = 822/1614) during the second wave. A total of 696 patients responded during both SARS-CoV-2-infection waves and were included in the analysis comparing patien …

Advancing Palliative Care Integration in Hematology: Building Upon Existing Evidence.

Opinion statementPatients with hematologic malignancies and their families are among the most distressed of all those with cancer. Despite high palliative care-related needs, the integration of palliative care in hematology is underdeveloped. The evidence is clear that the way forward includes standard-of-care PC integration into routine hematologic malignancy care to improve patient and caregiver outcomes. As the PC needs for patients with blood cancer vary significantly by disease, a disease-specific PC integration strategy is needed, allowing for serious illness care interventions to be ind

Paediatric Gliomas: BRAF and Histone H3 as Biomarkers, Therapy and Perspective of Liquid Biopsies.

Paediatric gliomas categorised as low- or high-grade vary markedly from their adult counterparts, and denoted as the second most prevalent c … . BRAF inhibitors (Dabrafenib and Vemurafenib), however, show higher overall survival and tumour response in BRAF V600E mutated pLGGs than conventional therapies in some studies. To date, targeted therapy and precision medicine are promising avenues for paediatric gliomas with BRAF V600E and diffuse intrinsic pontine glioma with the H3K27M mutations. G …

Delivering bad news in clinical hematology: a personal perspective.

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