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Facilitators and barriers to implementing patient-reported outcomes in clinical oncology practice: a systematic review based on the consolidated framework for implementation research.

BackgroundIn clinical oncology practice, patient-reported outcomes (PROs) are essential for assessing the symptom burden, quality of life, and psychological status of patients. However, there remains a gap between the use of PROs in an oncologic setting and its implementation. Furthermore, numerous reviews in PRO implementation are often based on one particular technology, setting, or health condition, making it difficult to obtain a comprehensive and coherent summary of available evidence to help plan and undertake implementation. This systematic review aims to identify and integrate enablers

Высокоагрессивный множественный склероз релапсируется во время беременности после инфекции SARS-COV-2: Case Report and Licture Review.

Мы сообщаем о сложном случае с 32-летней ранее здоровой беременной женщиной при 17+2-недельной беременности с новым диагнозом исключительно высокоактивного релапсирующего множественного склероза (RRMS), спровоцированного интенсивным острым респираторным синдромом коронавируса 2 (SARS-COV-2). Замечательными клиническими характеристиками были быстрое ухудшение клинического состояния, серьезность и характер симптомов, включая спастическую тетраплегию, диспнею, дисфагию, анартхрию и синдром сильной боли, что привело к необходимости интенсивной терапии и механической вентиляции в течение 24 часов.

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… (A) and (C) T2 flair sagittal: multifocal demyelination in the deep white matter in the supra- and infratentorial region, as well as in the pons and the cerebellar crus on the right. Demyelination is also found at the level of the medulla oblongata and at level C1 (red arrows). …

Potential Role of Bupropion Sustained Release for Cancer-Related Fatigue: a Double-Blind, Placebo-Controlled Study

Background: Cancer-related fatigue (CRF) is very common and can be experienced at all stages of disease and in survivors. CRF causes patients more distress than pain or nausea and vomiting. Different pharmacologic interventions have been evaluated for the management of CRF. The purpose of this study was to determine the efficacy of bupropion sustained release (SR) as a treatment for fatigue in patients with cancer. Methods: In this randomized, double-blind, placebo-controlled trial, patients with fatigue due to cancer were randomly assigned to either 150mg daily of bupropion SR or matching pla

Using nominal group technique to compare patients' and clinicians' perspectives on symptoms in multiple myeloma to inform the development of a self management tool for patients with relapsed myeloma.

BackgroundThe nominal group technique (NGT) allows stakeholders to directly generate items for needs assessment. The objective was to demonstrate the use of NGT to inform the development of a healthcare app in patients with relapsed myeloma. Healthcare professionals with experience in the care of patients with relapsed/refractory myeloma were invited to participate.MethodsOne NGT group was conducted. In the group, health care professionals working in haematology were asked to vote anonymously in order of highest priority, on symptoms previously highlighted by relapsed/refractory myeloma patien

Проект для самостоятельной мотивации: Качественное собеседование по вопросам предприимчивости выживших жертв рака к программам изменения цифрового здоровья.

СПРАВОЧНАЯ ИНФОРМАЦИЯ: Несмотря на повышенный риск рецидива, связанный с изменением образа жизни, многие лица, пережившие рак, не соблюдают рекомендации по укреплению здоровья. Цифровое медико-санитарное вмешательство открывает перспективы для поддержки изменений в поведении, однако лишь немногие исследования предусматривают участие выживших жертв в разработке мер вмешательства, что потенциально ограничивает эффективность реального мира. Понимание предпочтений и потребностей в поддержке выживших жертв рака имеет решающее значение для разработки эффективных мер по изменению поведения в цифровой

Delirium in cancer patients admitted to the intensive care unit: a retrospective study.

ObjectiveTo describe the occurrence of delirium in cancer patients admitted to the intensive care unit according to clinical and demographic characteristics.MethodsA retrospective study was conducted with 135 adults admitted to the intensive care unit of a public cancer hospital in the city of Rio de Janeiro, Brazil, between January and March 2016. Fisher's exact test and the linear association test were used to identify statistically significant associations between the occurrence of delirium and categorical and ordinal variables, respectively, considering a p-value ResultsThe overall occurre

Protective Isolation for Patients with Haematological Malignancies: A Pilot Study Investigating Patients' Distress and Use of Time.

Background: Patients with haematological malignancies are often hospitalized in protective isolation until full neutrophil recovery in order to prevent infections. This descriptive pilot study evaluate the level of isolation-related distress and the use of free time in a sample of Italian onco-haematological patients who were hospitalized in protective isolation. Materials and Methods: Participants were 18 patients hospitalized in hematologic ward to receive induction therapy (n=12) or autologous stem cell transplant (n=6). They completed a self-report questionnaire before discharge. Results:

Несоответствия в рецидивной или рефрактной множественной миеломе: рекомендации межпрофессиональной консенсусной группы.

Во многих исследованиях были зафиксированы расовые, социально-экономические, географические и другие различия для пациентов из Соединенных Штатов (США) с множественной миеломой, связанные с диагностикой и управлением прифронтовыми линиями. В отличие от этого, очень мало известно о различиях в регулировании рецидивов/изъятий множественной миеломы (RRMM), несмотря на множество новых вариантов лечения. В ходе этого обзора мы обсуждаем проявления неравенства в ПРМ и стратегии по смягчению их воздействия. Лекарства от иммуномодулирующих препаратов могут создавать различия по многим осям, например н

Interventions to improve cancer survivorship among Indigenous Peoples and communities: a systematic review with a narrative synthesis.

PurposeThe purpose of this systematic review is to synthesize the evidence on the types of interventions that have been utilized by Indigenous Peoples living with cancer, and report on their relevance to Indigenous communities and how they align with holistic wellness.MethodsA systematic review with narrative synthesis was conducted.ResultsThe search yielded 7995 unique records; 27 studies evaluating 20 interventions were included. The majority of studies were conducted in USA, with five in Australia and one in Peru. Study designs were cross-sectional (n=13); qualitative (n=5); mixed methods (

Cardiovascular and Cancer Risk: The Role of Cardio-oncology.

Cardio-oncology is a subspecialty of cardiology. It was created to address oncology data indicating that newly developed drugs for cancer treatment were having unanticipated cardiac side effects. Cardio-oncology designs primary and secondary risk strategies through surveillance as well as interventions to reduce cardiovascular risk (CVR), prevent cardiotoxicities, and manage the side effects that may occur. Rather than discuss in detail the cardiotoxicities of specific therapies or radiation, this review article will explore the interplay of cancer, cancer treatment, and CVR. It will examine t

Abstracts - IANCON 2025

Аннотация не предоставлена источником. Откройте карточку для перехода к публикации.

Patient-reported outcomes and health-related quality of life in individuals living with, through, and beyond cancer in Sweden: a cross-sectional study.

BackgroundThe use of patient-reported outcome measures (PROM) can be beneficial in several ways. However, presentations of PROM data from in … ence values, and other similar cancer studies.ResultsA total of 2,131 individuals responded (26% response rate). The results demonstrate consistent differences in C30 scale scores, where respondents with several comorbidities, younger age, and lung and colorectal cancer diagnoses had poorer scores. Respondents within problem ranges were consistent with …

Optimizing Care: Integrative Oncology in Myeloproliferative Neoplasm.

Purpose of reviewMyeloproliferative neoplasm (MPN) burdens the lives of those affected. MPN patients endure significant impacts on their physical, psychological, and social well-being. While pharmacological interventions offer some disease and symptom control, they often have unfavorable side effects. This review explores the potential of Integrative Oncology (IO) therapies in managing MPNs and their associated symptoms.Recent findingsIO is dedicated to augmenting conventional treatments through integrating interventions targeting the mind, body, nutrition, supplements, and other supportive ca

Incidence and Factors Influencing Locomotive Syndrome in Cancer Patients Living in the Community.

Background Investigating locomotive syndrome (LS) of cancer survivors in the community will help clarify the importance of rehabilitation for cancer survivors in the community and provide a basis for exploring effective interventions. The primary purpose of this study was to conduct a comparison of LS, fatigue, psychological problems, and physical activity in cancer survivors and those without cancer in the community. The secondary purpose was to analyze factors influencing LS in cancer patients. Methods The study involved 59 cancer patients undergoing chemotherapy at home and 59 people withou

Neuropsychiatric disorders in adults undergoing chimeric antigen receptor T cells therapy for aggressive lymphomas and acute lymphoblastic leukemia.

ObjectiveTo evaluate risk factors for neuropsychiatric disorders (NPD) in recipients of CART therapy.MethodsPatients ≥ 18 years with acute lymphoblastic leukemia (ALL), and aggressive B-cell lymphomas who received CART in 2018 were evaluated. Patients with and without NPD were compared.ResultsNPD was diagnosed in 31.2% of patients. Compared to patients without NPD, patients with NPD were likely to be females (P = 0.035) and have ALL (P = 0.039). NPD was significantly associated with female gender (OR = 2.03) and diagnosis of ALL (OR = 2.76). No association between NPD and outcomes.ConclusionsF

Злоумышленная малярия: результаты вскрытия и морфологические характеристики.

ВАЖНЯЯ малярия, обусловленная инфекцией плазмодия фальципарума, передающейся москитами < < Анофелес > > , представляет собой чрезвычайную ситуацию, угрожающую жизни людей и приводящую к высокому уровню смертности в странах Африки к югу от Сахары. P. falciparum инфицирует красные кровяные клетки, вызывая их агрегацию и сцепление с эндотелиальной облицовкой малых сосудов. Этот микроваскулированный секвестр может препятствовать кровотоку, что приводит к ишемии и кровоизлиянию в организм, вызванному разрывом небольших судов. В случае внезапной смерти диагноз возможен только после вскры

Совпадение в аннотации оригинала
BACKGROUND: Malignant malaria, resulting from Plasmodium falciparum infection transmitted by Anopheles mosquitoes, is a life-threatening eme … y was requested to determine the cause of death and to assess whether the infection was directly responsible or other factors were involved. This case highlights its iconographic importance, demonstrates scenarios relevant to pathologists, and underscores the need to always consider Plasmodium falciparum infection in the differential diagnosis of febri …

Response-The Road Less Travelled: Why did Miles Little Turn to Qualitative Research and Where Did This Lead?

Miles Little is an Australian surgeon, poet, and philosopher whose published work spans diverse topics in surgery, medicine, philosophy, and … to a current controversy in surgery, I argue that Little's survey of amputees models a laudable response to criticism, and in this respect, it is still relevant today.

Elevated serum Activin A in chronic obstructive pulmonary disease with skeletal muscle wasting.

OBJECTIVE: Muscle wasting contributes to the reduced quality of life and increased mortality in chronic obstructive pulmonary disease (COPD). Muscle atrophy in mice with cachexia was caused by Activin A binding to ActRIIB. The role of circulating Activin A leading to muscle atrophy in COPD remains elusive. METHODS: In the present study, we evaluated the relationship between serum levels of Activin A and skeletal muscle wasting in COPD patients. The expression levels of serum Activin A were measured in 78 stable COPD patients and in 60 healthy controls via ELISA, which was also used to determi

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… REFERENCES 1 Agusti AG Noguera A Sauleda J Sala E Pons J Busquets X Systemic effects of chronic obstructive pulmonary disease Eur Respir J 2003 21 2 347 60 10.1183/09031936.03.00405703 12608452 2 Engelen MP Schols AM Baken WC Wesseling GJ Wouters EF Nutritional depletion in relation to respiratory …

Abstracts - IANCON 2024

Аннотация не предоставлена источником. Откройте карточку для перехода к публикации.

Information-Seeking Patterns and Communication Preferences Among Japanese Survivors With Cancer: Cross-Sectional Analysis.

BackgroundWith increasing numbers of survivors with cancer, the importance of patient-centered information provision and communication to alleviate psychological burdens, such as anxiety and depression, is growing. However, substantial individual differences exist in patients with cancer information-seeking behaviors and use of support services, and few studies have comprehensively examined cognitive and psychological factors such as treatment status, sex, trust in information sources, and patient-provider relationships.ObjectiveThis study aimed to integrate the theory of planned behavior and