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An Observational Study of the First 100 Patients Undergoing Nocturnal Every-Other-Day Online Hemodiafiltration: Clinical Outcomes and Patient and Technique Survival.

Background: High-volume online hemodiafiltration (OL-HDF) has proven to be the most efficient dialysis modality and to offer better clinical outcomes in patients on hemodialysis. Longer and more frequent dialysis sessions have demonstrated clinical and survival benefits. Methods: A single-center observational study of the first one hundred patients on nocturnal every-other-day OL-HDF was conducted with the aim of reporting the experience with this treatment schedule and evaluating analytical and clinical outcomes as well as the patient and technique survival. Results: Nocturnal OL-HDF on alter

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… Pons M. Ramos R. Mora-Macià J. Carreras J. ESHOL Study Group High-efficiency postdilution online hemodiafiltration reduces all-cause mortality in hemodialysis patients J. Am. Soc. Nephrol. 2013 24 487 497 10.1681/ASN.2012080875 23411788 PMC3582206 16. Blankestijn P.J. Vernooij R.W. Hockham C. …

Мигрен и напряжённый тип голова ассоциируются с множественным склерозом: исследование по изучению конкретных случаев.

Справочная информация/задачи: За последние несколько десятилетий наблюдается рост научного интереса к распространенности заболеваний головной болью среди людей с MS (PwMS). Хотя последние данные свидетельствуют о наличии связи между мигренью и множественным склерозом, исследования дают непоследовательные результаты главным образом из-за методологических различий, включая небольшие размеры выборки, отсутствие контрольных групп, отсутствие структурированных дневников с головной болью и изменчивость диагностических критериев. Цель этого исследования состоит в том, чтобы решить вопрос о том, имеет

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… These areas include cortical regions, the thalamus, and brainstem nuclei such as the periaqueductal gray (PAG), the dorsal raphe nucleus (DRN) in the midbrain, and the locus coeruleus (LC) in the pons. …

Validation of the FACT-G7 in patients with hematologic malignancies.

BackgroundIt is essential to evaluate the quality of life in patients with hematologic malignancies to reflect the therapeutic effect and prognosis, but lengthy assessments are often burdensome. The 7-Item Functional Assessment of Cancer Therapy-General (FACT-G7) is a brief, easy, and rapid index for evaluating quality of life. Nevertheless, there is no report about its application in Chinese patients with hematologic malignancies.ObjectiveThe purpose of this study was to validate the Chinese version of the FACT-G7 for patients with hematologic malignancies.MethodsThis study is a cross-section

Identification of a potentially avoidable cardiopulmonary resuscitation in hematology and oncology wards.

BackgroundIn-hospital cardiopulmonary resuscitation (CPR) is one of undesirable situations. We tried to identify and characterize a potentially avoidable CPR in cancer patients who were hospitalized in hematology and oncology wards.MethodsA potentially avoidable CPR was determined based on chemotherapy setting, disease status and clinical situation at the time when a cardiopulmonary arrest occurred, by using a consensus-driven medical records review of two physicians.ResultsOne hundred thirty-seven patients among 12,437 patients hospitalized at hematology and oncology wards between March 2003

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… Psychooncology. 2013;22(12):2771–2778. doi: 10.1002/pon.3346. 17. Billings JA, Krakauer EL. On patient autonomy and physician responsibility in end-of-life care. Arch Intern Med. 2011;171(9):849–853. doi: 10.1001/archinternmed.2011.180. 18. …

Усугубляемость (SWI): Технические аспекты и применение в МРТ мозга при нейродегенеративных расстройствах.

Снимки, взвешенные по сузуптуальности (SWI), представляют собой последовательность магнитных резонансных изображений (MRI), чувствительных к веществам, изменяющим местное магнитное поле, таким, как кальций и железо, что позволяет проводить различие между фазной информацией. SWI представляет собой 3D-эчо-градиентную последовательность с высоким пространственным разрешением, которая обеспечивает эффект как фазового, так и масштабного эффекта. Взаимодействие парамагнитных (таких, как гемосидрин и деоксигемоглобин), диамагнитных (включая кальцинацию и минералы) и железомагнитных веществ с местным

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… Multiple microbleeds at the gray–white matter junction (excluding the posterior fossa) strongly suggest the diagnosis of CAA, distinguishing it from hypertensive microhemorrhages, which typically occur in the basal ganglia, thalami, pons, and cerebellum [ 64 ]. …

Сегментация с искусственным интеллектом и автоматизированный расчет индекса каллосу с корпусом при множественном склерозе.

ЦЕЛИ: Определить различия в индексе каллосум с корпусом (ККИ) между пациентами, страдающими хроническим множественным склерозом (MS), и здоровыми людьми, а также оценить сегментацию каллосумов с корпусом у пациентов с КБ с использованием технологий искусственного интеллекта. CCI может быть надежно измерен на магнитно-резонансной съемке (MRI) и предложен в качестве возможного маркера атрофии мозга в MS. В ходе этого исследования были сканированы 150 пациентов, страдающих МЗ (продолжительность болезни - 12,6 5,9 года), и 150 здоровых пациентов. Индекс corpus callosum был измерен вручную на основ

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… plaque appearing hypointense on T1-weighted (T1W) images and hyperintense on T2-weighted (T2W) images, and contrast-enhancing lesions defined as active plaque are the routinely used MRI parameters. 7 With MRI examination, the periventricular area, floor and roof of the 4th ventricle, periaqueduct, pons …

Symptoms after hospital discharge following hematopoietic stem cell transplantation.

AimsThe purposes of this study were to assess the symptoms of hematopoietic stem cell transplant patients after hospital discharge, and to determine the needs of transplant patients for symptom management.Materials and methodsThe study adopted a descriptive design. The study sample comprised of 66 hematopoietic stem cell transplant patients. The study was conducted in Istanbul. Data were collected using Patient Information Form and Memorial Symptom Assessment Scale (MSAS).ResultsThe frequency of psychological symptoms in hematopoietic stem cell transplant patients after discharge period (PSYCH

The lived experiences of social isolation among cancer patients: a systematic review and meta-synthesis.

BackgroundDespite significant improvements in cancer survival rates, social isolation remains a major threat to patient well-being and reintegration into society. This study systematically reviews and integrates qualitative findings to elucidate the lived experience of social isolation among cancer patients.MethodsA systematic search of PubMed, CINAHL, the Cochrane Library, PsycINFO, Embase, and Web of Science was conducted to identify qualitative studies involving patients with cancer that were published in English or Chinese from database inception to August 2025. The PRISMA guidelines were

Cancer survivorship: understanding the patients' journey and perspectives on post-treatment needs.

BackgroundCancer treatments have many adverse effects on patient's health leading to poor cardiorespiratory capacity, muscular- degeneration, fatigue, loss of strength and physical function, altered body-composition, compromised immune-function, peripheral neuropathy, and reduced quality of life (QOL). Exercise programs can significantly increase functional capacity when tailored to individual needs, thus improving health. Exercise interventions in cancer rehabilitation, when supported by appropriate nutrition can be effective in attaining a healthy weight and body-composition. The successful

Antioxidant and Antiproliferation Activities of Lemon Verbena (Aloysia citrodora): An In Vitro and In Vivo Study.

Aloysia citrodora (Verbenaceae) is traditionally used to treat various diseases, including bronchitis, insomnia, anxiety, digestive, and heart problems. In this study, this plant's antioxidant and anti-proliferation effects were evaluated. In addition to volatiles extraction, different solvent extracts were prepared. The GC-MS, LC-MS analysis and the Foline-Ciocalteu (F-C) method were used to investigate the phytochemical components of the plant. MTT assay was used to measure the antiproliferative ability for each extract. Antioxidant activity was determined using the 2,2-diphenylpicrylhydrazy

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… Pons A. Roche E. Micol V. Effect of lemon verbena supplementation on muscular damage markers, proinflammatory cytokines release and neutrophils’ oxidative stress in chronic exercise Eur. J. Appl. Physiol. 2011 111 695 705 10.1007/s00421-010-1684-3 20967458 18. Funes L. Fernández-Arroyo S. … Pons A. Roche E. Segura-Carretero A. Fernández-Gutiérrez A. Micol V. Correlation between plasma antioxidant capacity and verbascoside levels in rats after oral administration of lemon verbena extract Food Chem. 2009 117 589 598 10.1016/j.foodchem.2009.04.059 19. Schmid R. Bruneton J. Hatton C.K. …

A multidisciplinary perspective on the complex interactions between sleep, circadian, and metabolic disruption in cancer patients.

Sleep is a basic need that is frequently set aside in modern societies. This leads to profound but complex physiological maladaptations in the body commonly referred to as circadian disruption, which recently has been characterized as a carcinogenic factor and reason for poor treatment outcomes, shortened survival, and reduced quality of life in cancer patients. As sleep and circadian physiology in cancer patients spans several disciplines including nursing science, neurology, oncology, molecular biology and medical technology, there is a lack of comprehensive and integrated approaches to deal

Physical Performance, Sarcopenia and Malnutrition-Basic Test Set for Everyday Use in Cancer Therapy.

PURPOSE: Testing physical performance, malnutrition, and sarcopenia is recommended in numerous guidelines for hematological-oncological patients. However, due to economic conditions and the large number of test options, these tests have not made it into clinical routine. The aim of this study is to propose a practical compromise that could allow routine testing under the current conditions. METHODS: We conducted a prospective, monocentric, small-scale cohort study. In our interdisciplinary tumor outpatient clinic, we investigated time required for malnutrition screening (PG-SGA long form), ma

A retrospective review of the management of patients following a malignancy diagnosis on biologic therapies for the treatment of dermatological disorders.

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… Pons Benavent M. Guillén-Climent S. Montesinos Villaescusa E. Successful outcome of psoriasis in a laryngeal cancer patient treated with ixekizumab, a possible beneficial treatment for both pathologies Dermatol Online J 27 6 2021 1 3 10.5070/D327654071 34387071 20 Valenti M. Pavia G. Gargiulo L. …

Cancer in the Adolescent and Young Adults (AYA) and Children: A Comprehensive Analysis of the Epidemiology and Psychosocial Morbidity in the Indian Population.

Bhupesh GuleriaAims Adolescent and young adults (AYAs), children with cancer, and their guardians have unique psychosocial morbidities adver … 06% had overall NCCN distress score ≥ 4. Also, 73.81 and 79.49% had "quite a bit" or "very much" responses on functional and symptom scales, respectively, in EORTC QLQ C-30 questionnaire. Peds QL version 3.0 revealed total score ranging from 276 to 523 for each patient. Conclusion AYAs and children with cancer are extremely vulnerable to psychological …

Frailty Prevalence and Characteristics in Older Adults with Hematologic Cancer: a Descriptive Study.

ObjectiveThis study investigated the prevalence of frailty in older patients with hematologic cancer and assessed the association between older patients' characteristics and frailty.MethodsThis descriptive study enrolled 90 older patients undergoing treatment for hematological malignancies at an oncology hospital. Frailty was assessed with the Edmonton Frailty Scale as not frail (0-4), apparently vulnerable (5-6), mildly frail (7-8), moderately frail (9-10), and severely frail (11-17). The association of frailty and older patient characteristics and diagnosis was assessed by logistic regressio

Serum Interleukin-6 is Not Linked with Sleep-Quality, Restless Legs Syndrome, and Depression, But with 6-Month Survival in Hematological Malignancies.

BackgroundSerum interleukin (IL)-6 has been found to be associated with sleep quality, mood, and survival in patients with solid tumors. Results in these studies were confounded by knowledge of diagnosis to study subjects. Moreover, such data among subjects with hematological malignancies and data regarding restless legs syndrome is limited. The present study was, therefore, conducted to assess the sleep quality, depression, and restless leg syndrome in hematological malignancies and to study if there is any role of IL6 associated with it.MethodsSixty-six subjects having hematological malignan

Current status of cancer immunotherapy.

To prove clinical benefits of cancer vaccine is currently difficult, except for one phase III trial has documented improved overall survival with the vaccine, Sipuleucel-T, although induction of anti-tumor immune responses through cancer vaccine is theoretically promising and would be straightforward. In contrast, immune checkpoint blockade with anti-CTLA4 mAb and anti-PD-1 mAb has demonstrated clear evidence of objective responses including improved overall survival and tumor shrinkage, driving renewed enthusiasm for cancer immunotherapy in multiple cancer types. In addition, there is a promi…

Methods for nutrition monitoring in cancer patients: a cognitive perspective.

In the present medical context, the evaluation and the monitoring of factors other than mere physical symptoms are an urgent demand. In particular, the issue of quality of life (QoL) has become a relevant target in the treatment of cancer. However, the approach towards these aspects is not well standardized and the actual applications in a concrete setting are fragmented, left to personal or local initiative. If this is true for QoL in general, it is particularly relevant in the specific field of nutrition. Indeed, though the growing awareness of a correlation between chronic diseases and diet

Predictors of Transplant Regret: A Case-Control Study Nested Within a Prospective Cohort of HSCT Recipients.

ObjectiveTo explore pre-hematopoietic stem cell transplant (HSCT) demographic, disease, and psychological factors predictive of future transplant regret and to determine post-HSCT variables associated with regret.Patients and methodsHSCT candidates participated in a prospective cohort study (June 2008-October 2013) examining health behaviors and HSCT outcomes, including completion of standardized surveys at pre-HSCT (baseline) and 1-year post-HSCT. Cases were participants that endorsed regret at 1-year post-HSCT follow-up, and controls were participants without regret at 1 year, matched on age

The therapeutic potential of bedside art observation in hematologic cancer inpatients: a randomized controlled pilot study.

PurposePrior research has suggested that art-based interventions may reduce anxiety in cancer patients and enhance dialogue in the healthcare setting. Through implementing Art at the Bedside, an art-based hospital visitation program, we sought to examine whether dedicated art observation sessions, and varying formats (with and without guided discussion), could have therapeutic effects on cancer patients' mental wellbeing.MethodsThis randomized controlled pilot study evaluated the effects of bedside art observation on anxiety in a sample of 73 hematologic cancer inpatients. We compared state an