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Avian Orthoreovirus in China: Molecular Evolution, Transmission Ecology, Immune Modulation, and Integrated Control in the Genomic Era.

Avian orthoreovirus (ARV) has re-emerged as one of the most important viral pathogens affecting modern poultry production worldwide. In Chin … able ARV control will likely require genome-informed and adaptive prevention frameworks integrating virology, immunology, epidemiology, and precision poultry management.

Evaluation of the Analytical Performance of the STANDARD Q COVID-19 Antigenic Test in Suspected COVID-19 Cases in Bobo-Dioulasso, Burkina Faso.

BACKGROUND: The use of alternative technique such as rapid antigen diagnostic tests (Ag-RDTs) is needed in countries with limited resources for fast tracking of COVID-19 cases. This study evaluated the performance of the STANDARD Q COVID-19 antigen test compared with reverse transcriptase polymerase chain reaction (RT-PCR) among suspected COVID-19 cases using nasopharyngeal and/or oropharyngeal swabs in Bobo-Dioulasso, Burkina Faso. METHODS: A cross-sectional study was conducted from April to September 2021. The respiratory secretions of suspected COVID-19 cases were collected at the Virology…

Comparative Analysis of Upper Respiratory Viral Infections in Kidney Transplant Recipients and the Immunocompetent Pediatric Population.

OBJECTIVES: This study aimed to compare the clinical, laboratory, and virology profiles of pediatric kidney transplant recipients and immunocompetent children presenting with upper respiratory tract infection, evaluated using multiplex viral polymerase chain reaction panels. MATERIALS AND METHODS: This single -center retrospective cohort study included 31 kidney transplant recipients (aged 7 -16 years ) and 80 age -matched immunocompetent children who presented with upper respiratory tract infection at Başkent University Hospital from January 2023 to March 2025. Demographic, clinical, and lab…

Dual IgM seropositivity for dengue and chikungunya among suspected dengue cases: A hospital-based observational study from Northwestern Karnataka.

PURPOSE: Dengue virus (DENV) and Chikungunya virus (CHIKV) are significant arboviruses transmitted by Aedes mosquitoes. The concurrent circu … HIKV) IgM antibodies were detected using Indian Council of Medical Research - National Institute of Virology (ICMR-NIV) Immunoglobulin M Antibody Capture (MAC) Enzyme Linked Immunosorbent Assay (ELISA) kits. The reported sensitivity and specificity were 98.53% and 98.84% for DENV IgM ELISA and 95% and 98% for CHIKV IgM ELISA, respectively. RESULTS: Dual I …

The Re-Emergence of Bundibugyo Ebolavirus in Uganda and the Democratic Republic of Congo: Epidemiological Drivers, Response Strategies, and Implications for Global Health Security.

Bundibugyo ebolavirus (BDBV) is one of the least studied species within the genus Orthoebolavirus (family Filoviridae), despite its capacity … Google Scholar, and Embase from inception to 12 August 2026, to examine BDBV historical evolution, virology and pathogenesis, drivers of re-emergence, surveillance and response, therapeutic and vaccine gaps, and global health security implications. The 2026 outbreak, unfolding amid conflict and mass displacement in eastern DRC, has been marked by an estim …

Bibliometric characteristics of highly cited publications from the Indian Journal of Medical Research.

Background and objectives Indian Journal of Medical Research (IJMR), established in 1913, is a cornerstone of Indian biomedical scholarship. … post-2016. Communicable diseases led thematically (e.g., bacterial infections: 33 papers, 5,478 TC; virology: 23 papers, 3,432 TC), followed by non-communicable foci like diabetes (21 papers). India dominated (148 papers; >70%), with All India Institute of Medical Sciences (AIIMS)-New Delhi (23 papers; CPP: 181.5) and Indian Council of Medical Research (IC …

The global trends and clinical progress in influenza co-infection: a visualization and bibliometric analysis (2005-2025).

OBJECTIVES: Influenza co-infection, characterized by concurrent or sequential infection with influenza and other pathogens, lacks comprehens … h Hospital. "PLOS ONE" and "BMC Infectious Diseases" published the most articles, while "Journal of Virology" and "Journal of Infectious Diseases" were the most cited. Keywords such as "infection", "virus", "COVID-19", "children", and "respiratory syncytial virus" highlighted research hotspots and emerging trends in influenza co-infection. The study of pat …

Parvovirus B19 Rebound.

Human parvovirus B19 (B19V) is responsible for a wide clinical spectrum ranging from asymptomatic infection, through mild disease, up to life-threatening one. Outbreaks are registered every 3-4 years, and a recent international alert for a new outbreak has been released. The experience of B19 virus circulation in a 600-bed tertiary care pediatric hospital in Rome from 2018 to 2024 is reported here. This retrospective study involved a total of 9695 blood samples (about 8500 patients), 11 amniotic fluids (11 pregnant women), and 10 827 sera (about 9500 patients), processed in the Virology Unit o…

Charting the Proteins of Oropouche Virus.

Oropouche virus (OROV) is an emerging arbovirus responsible for Oropouche fever, also known as sloth fever, a febrile illness that can lead … al diagnostics and vaccine candidates. Our findings contribute critical insights into the molecular virology of OROV and provide a foundational framework for future efforts aimed at the prevention, diagnosis, and control of this neglected tropical pathogen. These advancements are essential for mitigating the impact of OROV in endemic regions and reducing t …

CRISPR-Cas13a coupled with recombinase aided amplification: Development of an ultrasensitive point - of - care detection method for visual diagnosis of egg drop syndrome virus.

Egg Drop Syndrome Virus (EDSV) infection in poultry causes a significant drop in egg - laying rate, harming poultry farms' economic benefits … .94. This assay provides a potential point - of - care testing approach for the clinical detection, virology, and epidemiological studies of EDSV.

A Comprehensive Review of the Neglected and Emerging Oropouche Virus.

Oropouche virus (OROV) is a neglected and emerging arbovirus that infects humans and animals in South and Central America. OROV is primarily … nts or vaccines are available. In this article, we review the most recent progress in understanding virology, transmission, pathogenesis, diagnosis, host-vector dynamics, and antiviral vaccine development for OROV, and provide implications for future research directions.

Risk factors for prolonged mechanical ventilation in critically ill patients with influenza-related acute respiratory distress syndrome.

BACKGROUND: Patients with influenza-related acute respiratory distress syndrome (ARDS) are critically ill and require mechanical ventilation (MV) support. Prolonged mechanical ventilation (PMV) is often seen in these cases and the optimal management strategy is not established. This study aimed to investigate risk factors for PMV and factors related to weaning failure in these patients. METHODS: This retrospective cohort study was conducted by eight medical centers in Taiwan. All patients in the intensive care unit with virology-proven influenza-related ARDS requiring invasive MV from January…

Обезьяна: Вирусная зоонотическая болезнь возрождающегося глобального волнения.

Monkeypox (mpox) — редкое вирусное зоонотическое заболевание, эндемичное для Центральной и Западной Африки, вызванное вирусом обезьянопокс, ортопоксирусом, похожим на вирус вариолы (mallpox). Хотя эпизодические случаи, связанные с поездками, исторически происходили за пределами Африки, в мае 2022 года мпокс начал распространяться во всем мире во многих не эндемических странах на нескольких континентах. В 2024 году число зарегистрированных во всем мире случаев заболевания мпоксом и смерти от него возросло, в результате чего это стало одной из чрезвычайных ситуаций в области общественного здраво

Совпадение в аннотации оригинала
Monkeypox (mpox) is a rare viral zoonotic disease, endemic to Central and West Africa, caused by the monkeypox virus, an orthopoxvirus simil … ilding global capacity for outbreak response. This review summarizes the current literature on mpox virology, epidemiology, pathogenesis, clinical manifestations, diagnostics, treatment, prevention, and public health control measures. Ongoing investigation and research are needed to better understand mpox's evolving epidemiology, pathogenicity, transmissib …

Understanding Viral Haemorrhagic Fevers: Virus Diversity, Vector Ecology, and Public Health Strategies.

Viral haemorrhagic fevers encompass a diverse group of severe, often life-threatening illnesses caused by viruses from multiple families, in … anage outbreaks. This review discusses the necessity of interdisciplinary approaches that integrate virology, ecology, and public health to enhance diagnostic capabilities, develop vaccines and antivirals, and improve outbreak interventions. Exploring the ecological and biological dynamics of VHFs will help bolster a deeper understanding of these emerging …

West Nile virus seropositivity in Alanya, a coastal city in the Mediterranean region of Turkey.

BACKGROUND: West Nile virus (WNV)-related illness is a global health problem. Understanding the seropositivity rates and identifying the risk factors related to WNV in various animal species including humans is crucial for the implementation of effective prevention strategies. OBJECTIVES: Assess the rate of seropositivity and the risk factors associated with WNV seropositivity. DESIGN: Descriptive, cross-sectional. SETTING: Microbiology and virology departments in a veterinary college. PATIENTS AND METHODS: In a sample of healthy human participants in Alanya, located close to regions where…

David Taylor-Robinson: Medical Microbiologist and Research Pioneer of Sexually Transmitted Infections.

David Taylor-Robinson has been an inspiration to many investigators in the field of sexually transmitted infections (STIs) as, arguably, the father of modern mycoplasmology. Born in 1931, his career as a physician-scientist was initially in virology, researching chickenpox and the common cold, for both of which he made key discoveries at a time when little was known about these conditions. Soon, however, David's attention turned to bacteriology, developing a passionate interest in mycoplasmas and chlamydia. This gave rise to research collaborations all around the world in marginalized and regi…

Clinical Presentation and Management of Pulmonary Infection Caused by Mycobacterium paraffinicum.

Non-tuberculous mycobacteria (NTM) are environmental organisms that rarely cause infections in healthy individuals but can be opportunistic … r wall thickening, and bilateral inflammatory nodules. The patient was initially managed as TB, but virology and serology screens were negative for common pathogens, including TB. The pivotal biopsy identified the NTM infection, leading to a revised diagnosis. Treatment was managed by a multidisciplinary team and included a regimen of rifampicin, ethambuto …

Gender-specific effects of COVID-19 lockdowns on scientific publishing productivity: Impact and resilience.

RATIONALE: The SARS-CoV2 pandemic led to drastic social restrictions globally. Early data suggest that women in science have been more adver … red by women than those on other topics, a finding not likely due to particular gender imbalance in virology or viral epidemiology, since publications on HIV followed similar patterns to previous years. By 2021, this imbalance had reversed, with more COVID-19-related papers authored by women than men. CONCLUSIONS: These data suggest women from Victoria we …

[Assessment of antimicrobial activity of bioflavonoid CITROX and chlorhexidine combination against P. gingivalis (in vitro)].

OBJECTIVE: The aim of the study - evaluation of the antiseptic properties of the combination of chlorhexidine and bioflavonoid CITROX against P. gingivalis. MATERIAL AND METHODS: Clinical isolates of microbial cultures from the collection of the Department of Microbiology, Immunology, Virology of the Moscow State Medical University named after A.I. Evdokimov: P. gingivalis. Primary seeding of the studied material was carried out on nutrient media produced by Himedia Laboratories Pvt. Limited (India): Colombian agar with the addition of 5% defibrinated blood and a selective additive for the is…

Counteracting Immunosuppression in the Tumor Microenvironment by Oncolytic Newcastle Disease Virus and Cellular Immunotherapy.

An apparent paradox exists between the evidence for spontaneous systemic T cell- mediated anti-tumor immune responses in cancer patients, ob … nted from the aggressive brain tumor glioblastoma multiforme. The last decades of basic research in virology, oncology and immunology can be considered as a success story. Based on discoveries of these research areas, translational research and clinical studies have changed the way of treatment of cancer by introducing and including immunotherapy.