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Aseptic meningo-radiculo-encephalitis presenting initially with urinary retention: a variant of acute disseminated encephalomyelitis.

We report three male patients with aseptic meningoencephalo- radiculitis presenting with acute urinary retention. Viral antibody titers for … nctional recovery with the disappearance of abnormal MRI findings.However, all three were left with erectile dysfunction, and two continued to use self-intermittent catheterization at more than 3-year follow-up. There was no recurrence of symptoms. The underlying causes remain unclear, though they may represent a variant of acute disseminated encephalomyelitis.

Evaluation of autonomic innervation of the clitoris and bulb.

PURPOSE: Female sexual dysfunction is a common disorder but there are few objective measures of female genital function. We present a novel technique to record electrical activity of the female genital erectile tissue. MATERIALS AND METHOD: We placed concentric needle electrodes in the right clitoral crus and the bulb of 22 healthy women. Following spontaneous activity recording we stimulated the median nerve to activate the sympathetic nervous system. We simultaneously measured evoked activity in the clitoris and bulb, and hand sympathetic skin responses (SSRs). RESULTS: Spontaneous electri

Epididymectomy is an effective treatment for scrotal pain after vasectomy.

OBJECTIVE: To investigate the efficacy of epididymectomy in patients with significant scrotal pain after vasectomy. PATIENT AND METHODS: Si … following were indicators of a poor outcome: atypical symptoms including testicular or groin pain; erectile dysfunction and normal appearance of the epididymis on ultrasonography. Patients with bilateral scrotal pain can have a good outcome after epididymectomy. CONCLUSION: Epididymectomy in well-selected patients is a reliable and effective treatment for pain after …

The Interplay Between Alexithymia and Sexual Function: A Systematic Review.

OBJECTIVE: Alexithymia represents a difficulty in identifying and describing emotions in oneself and others, and a reduced ability to reflec … of alexithymia than control subjects. The studies considered demonstrate that subjects experiencing erectile dysfunction exhibit higher levels of alexithymia than control groups. However, this result does not appear consistent in the case of female subjects encountering lubrication difficulties. There is also complete consensus among studies regarding the relationship …

Definitions, classification, and epidemiology of sexual dysfunction: a consensus statement from the Fifth International Consultation on Sexual Medicine 2024.

INTRODUCTION: The creation and maintenance of accurate definitions for sexual dysfunction and sexual health of women and men represents a fo … gasmia, compulsive sexual behavior disorder, decreased libido, delayed ejaculation, dysejaculation, erectile dysfunction, genital dysmorphophobia, hard flaccid syndrome, hypoactive sexual desire disorder, micropenis, Peyronie's disease, post-orgasmic illness syndrome, premature ejaculation, restless genital syndrome, and retrograde ejaculation. CONCLUSIONS: Multiple …

Сексуальное и репродуктивное здоровье в неврологических расстройствах: рекомендации пятого Международного консультативного совещания по вопросам сексуальной медицины (ICM 2024).

ВВЕДЕНИЕ: Неврологические расстройства влияют как на центральную, так и на периферийные нервные системы, часто приводящие к сексуальной дисфункции (SD). Эти условия сказываются не только на гениталиях, но и на сенсорных и моторных способностях, ощущении боли, мочевом пузыре и контроле кишечника, настроении и гормональном балансе. Несмотря на то, что сексуальное здоровье имеет важное значение для общего качества жизни, УР у лиц с неврологическими расстройствами по-прежнему остается предметом рассмотрения. ЦЕЛИ: Цель настоящего обзора состоит в том, чтобы дать обзор УР у лиц с неврологическими р

Совпадение в аннотации оригинала
INTRODUCTION: Neurological disorders impact both the central and peripheral nervous systems, often leading to sexual dysfunction (SD). These … pproaches. RESULTS: Sexual dysfunction in neurological disorders varies by condition. For example, erectile dysfunction (ED) and anejaculation are common in spinal cord injury, while Parkinson's disease may be associated with hypersexuality and orgasmic disorders. Brain injuries such as traumatic brain injury, stroke, and neurodegenerative diseases can reduce libido …

Relation between Baseline Height and New Diabetes Development: A Nationwide Population-Based Study.

PURPOSE: This scoping review examines the extent and focus of scientometric studies on male infertility and male sexual dysfunctions (MSDs) … ains centered on surgical interventions and their reproductive implications. In the domain of MSDs, erectile dysfunction (ED), especially diabetes-related ED, has seen a surge in research attention, with innovative treatments showing promise for future clinical applications. Despite progress in these areas, the review identifies significant gaps in research on prematu …

Association of sexual dysfunction according to DSM-5 diagnostic criteria with avoidance of and discomfort during sex in a population-based sample.

BACKGROUND: Sexual dysfunction frequencies and diagnostic indicators among older populations are relevant for public health measures, but evidence from large population-based studies is still scarce. AIM: To determine sexual dysfunction frequencies for women and men according to the Diagnostic and Statistical Manual of Mental Disorders (fifth edition; DSM-5) among 45- to 74-year-old participants of the population-based Hamburg City Health Study and the factors associated with sexual dysfunction diagnoses. METHODS: We determined sexual dysfunction frequencies according to the DSM-5 and the fa

Novel variants and rare clinical presentations in MFN2-related Charcot-Marie-Tooth disease: Insights from 10 families.

BACKGROUND: Charcot-Marie-Tooth disease (CMT) is a genetically heterogeneous group of inherited neuropathies, and MFN2-related CMT is a comm … ess, foot deformities, and sensory impairments were accompanied by rare clinical findings including erectile dysfunction (3/8 males), cognitive dysfunction, and central nervous system (CNS) abnormalities apparent on brain magnetic resonance imaging (MRI). Notably, two individuals carried biallelic MFN2 variants displaying AR MFN2-related CMT: one compound heterozygote …

Sildenafil (Viagra) Aggravates the Development of Experimental Abdominal Aortic Aneurysm.

Background cGMP-hydrolyzing phosphodiesterase type 5 (PDE5) regulates vascular smooth muscle cell (SMC) contraction by antagonizing cGMP-dependent protein kinase I (PKGI)-dependent SMC relaxation. SMC contractile dysfunction is implicated in the pathogenesis of aortic aneurysm. PDE5 inhibitors have been used for treating erectile dysfunction, such as drug Viagra (sildenafil). However, a few clinical cases have reported the association of Viagra usage with aortic dissection, and reduced PDE5A expression was found in human aortic aneurysm tissues. Therefore, we aimed to investigate the effect of…

Splenectomy is associated with sexual dysfunctions and decreased libido.

The removal of the spleen due to disease or trauma may be followed by disorders due to the asplenism, including immunodeficiency, hematological and metabolic diseases, mainly dyslipidemia, which can lead to sepsis, pulmonary embolism and early death. Although patients frequently report sexual disinterest after splenectomy, this feature has been experimentally studied only in a translational investigation performed by the same group of this work. To study libido and other sexual functions after the complete removal of the spleen in humans. This study was performed on 60 healthy adults, 30 men a

[Post-traumatic syringomyelia: What should know the urologist?].

The incidence of post-traumatic syringomyelia (PTS) is estimated according to recent studies at 25 to 30% of patients with traumatic spinal … es stable for certain time. In urologic practice, new neurological symptoms could be bladder and/or erectile dysfunction. The medical management based on prevention efforts with closed-glottis pushing, which could aggravate the syrinx cavity. In urology, extracorporeal shockwave lithotripsy, and laparoscopic or robotic surgery could extend the syrinx cavity for the sa …

Gonadal dysfunction in men with chronic kidney disease: clinical features, prognostic implications and therapeutic options.

Gonadal dysfunction is a frequent finding in men with chronic kidney disease and with end-stage renal disease. Testosterone deficiency, usua … l implications with regards to kidney disease progression, derangements in sexual drive, libido and erectile dysfunction, development of anemia, impairment of muscle mass and strength, and also progression of atherosclerosis and cardiovascular disease. Additionally, low testosterone levels in hemodialysis patients have been associated with increased mortality risk in …

A negative electroretinogram (ERG) in a case of probable multiple system atrophy (MSA).

Recent articles have described negative ERGs in a small number of patients with cerebellar degeneration. Five of the previously reported seven cases were hereditary (2/5 had spinocerebellar ataxia-1 (SCA-1) gene mutations) and the other two were sporadic. We report a negative ERG in a case of cerebellar degeneration that differs significantly from earlier cases. The 65-year-old man had a 5-year history of ataxia, unsteady gait, orthostatic hypotension, and bladder and erectile dysfunction, with no family history of neurological or retinal disease. Visual acuity was 20/30 OD, 20/40 OS, but repo…

Sexual dysfunction and cardiac risk (the Second Princeton Consensus Conference).

Recent studies have highlighted the relation between erectile dysfunction (ED) and cardiovascular disease. In particular, the role of endothelial dysfunction and nitric oxide in ED and atherosclerotic disease has been elucidated. Given the large number of men receiving medical treatment for ED, concerns regarding the risk for sexual activity triggering acute cardiovascular events and potential risks of adverse or unanticipated drug interactions need to be addressed. A risk stratification algorithm was developed by the First Princeton Consensus Panel to evaluate the degree of cardiovascular ris…

Dehydrated human amniotic membrane for early return of erectile function after robotic radical prostatectomy: a 10-year journey and lessons learned.

The first description of dehydrated human amniotic membrane (dHAM) use in robotic urologic surgery was by Razdan et al. in 2014 at the World Congress of Endourology. Since then, it has been utilized as a nerve and anastomotic wrap to enhance early return of erectile function and continence, respectively, during robotic radical prostatectomy (RALP). We describe our ten-year experience with dHAM as a nerve wrap. After obtaining hospital institutional review board (IRB) approval, a retrospective review of a prospectively maintained single center prostate cancer database was performed. All men und

Three Decades of Change in Frequency of Sexual Intercourse and Sexual Function Among Japanese Men: A Comparative National Survey.

OBJECTIVE: This study aimed to examine trends in frequency of sexual intercourse and sexual function among Japanese men over the past 30 years by comparing the Nationwide Survey conducted by the Japanese Society for Sexual Medicine in 2023 with the Sapporo Survey conducted by the Department of Urology, Sapporo Medical University, in 1991. METHODS: Three domains were analyzed: sexual intercourse, penile rigidity, and morning erections in both studies. To minimize inconsistencies, definitions were standardized. The 2023 survey included 3795 men aged 20-79 years, while the 1991 survey comprised

Measuring the Impact of Common Prostate Cancer Survivorship Conditions With Health Utilities.

OBJECTIVE: To assess the effect of disease exposure on the perceived impact of common prostate cancer (CaP) survivorship conditions and their surgical treatments. MATERIALS AND METHODS: Two cohorts-disease-exposed (DE) patients treated for CaP and disease naïve (DN) recruited from Qualtrics-were given standardized clinical scenarios on stress urinary incontinence (SUI) and erectile dysfunction (ED) and asked to assess disease impact using four health state utility (HSU) instruments which were averaged and reported in Quality-Adjusted-Life-Years (QALY; range 0.0 [death] to 1.0 [perfect health])…

Preliminary clinical association between the Nerve-Sparing Quality (NSQ) Score and early functional outcomes after robot-assisted radical prostatectomy.

INTRODUCTION: Nerve-sparing during robot-assisted radical prostatectomy (RARP) plays a critical role in postoperative functional recovery, particularly urinary continence and erectile function. Although several tools exist for assessing surgical performance in robotic surgery, objective intraoperative evaluation of nerve-sparing quality remains limited. The Nerve-Sparing Quality (NSQ) Score was recently introduced as a structured intraoperative scoring system designed to evaluate the technical quality of neurovascular bundle preservation. The aim of the present study was to explore the prelimi

Early experience with robot-assisted radical prostatectomy using the Toumai system: outcomes from the first African series of 134 patients.

Robot-assisted radical prostatectomy (RARP) is widely used for localized prostate cancer, offering enhanced precision and potential preservation of urinary and sexual function. Data on new robotic platforms in Africa are limited. Evaluate the safety, feasibility, and early perioperative, oncological, and functional outcomes of robot-assisted radical prostatectomy performed using the Toumai robotic system and determine whether these outcomes are consistent with those reported for established robotic platforms. We retrospectively analyzed 134 patients who underwent RARP with the Toumai system be