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Trigeminal neuropathy causes hypomyelination in the anterior cingulate cortex, disrupts the synchrony of neural circuitry, and impairs decision-making in male rats.

Infraorbital nerve-chronic constriction injury (ION-CCI) has become the most popular chronic trigeminal neuropathic pain (TNP) injury animal model which causes prolonged mechanical allodynia. Accumulative evidence suggests that TNP interferes with cognitive functions, however the underlying mechanisms are not known. The aim of this study was to investigate decision-making performance as well as synaptic and large-scale neural synchronized alterations in the spinal trigeminal nucleus (SpV) circuitry and anterior cingulate cortex (ACC) neural circuitry in male rats with TNP. Rat gambling task sh…

Childhood attention problems mediate effects of child maltreatment on decision-making performance in emerging adulthood.

Decision-making impairments during emerging adulthood confer risk for challenges in social and occupational roles and may increase the odds … e current study includes a subset of participants (n = 379) from Wave 1 who completed the Cambridge Gambling Task (CGT) at Wave 2 (Mage = 19.68, SD = 1.12; 77.3% Black/African American, 11.1% White, 7.7% Hispanic, 4.0% Other race). The CGT measured decision-making performance by assessing betting behavior across trials that differed in probability of winni …

The effects of combination levodopa-ropinirole on cognitive improvement and treatment outcome in individuals with cocaine use disorder: A bayesian mediation analysis.

BACKGROUND: Chronic cocaine users show impairments in cognitive processes associated with dopamine (DA) circuitry. Medications aimed at bols … ks. Potential cognitive mediators assessed at week 5 consisted of measures of decision-making (Iowa Gambling Task, Risky Decision-Making Task), attention/impulsivity (Immediate Memory Task), motivation (Progressive Ratio task), and cognitive control (Cocaine Stoop task). The primary outcome measure was the treatment effectiveness score (TES) calculated as …

Curvilinear associations between sexual orientation and problematic substance use, behavioural addictions and mental health among young Swiss men.

BACKGROUND AND AIMS: It is well documented that individuals with a minority sexual orientation face greater risks of problematic substance u … substance use (e.g. alcohol, cigarettes, cannabis and other illegal drugs), behavioural addictions (gambling, gaming, cybersex, internet, smartphone, work, exercise) and indicators of mental health (e.g. depression, stress). Curvilinear associations between sexual orientation (heterosexual, mostly-heterosexual, bisexual, mostly-homosexual or homosexual ind …

Which conditions should be considered as disorders in the International Classification of Diseases (ICD-11) designation of "other specified disorders due to addictive behaviors"?

BACKGROUND: Gambling and gaming disorders have been included as "disorders due to addictive behaviors" in the International Classification of Diseases (ICD-11). Other problematic behaviors may be considered as "other specified disorders due to addictive behaviors (6C5Y)." METHODS: Narrative review, experts' opinions. RESULTS: We suggest the following meta-level criteria for considering potential addictive behaviors as fulfilling the category of "other specified disorders due to addictive behaviors": 1. Clinical relevance: Empirical evidence from multiple scientific studies demonstrates that …

Transdiagnostic or Disorder Specific? Indicators of Substance and Behavioral Addictions Nominated by People with Lived Experience.

Using a transdiagnostic perspective, the present research examined the prominent indicators of substance (alcohol, cocaine, marijuana, tobacco) and behavioral (gambling, video games, sex, shopping, work, eating) addictions nominated by people with lived experiences. Specifically, we aimed to explore whether the perceived most important indicators nominated were consistent across the 10 addictions or differed based on the specific addiction. Additionally, we explored gender differences in the perceived most important indicators across addictive behaviors. A large online sample of adults recruit…

Shared gray matter alterations in individuals with diverse behavioral addictions: A voxel-wise meta-analysis.

BACKGROUND AND AIMS: Numerous studies on behavioral addictions (BAs) have reported gray matter (GM) alterations in multiple brain regions by … SIONS: Our findings on BAs were mainly derived from internet gaming disorder (IGD) and pathological gambling (PG) studies, preliminarily suggesting that GM atrophy in the prefrontal and striatal areas might be a common structural biomarker of BAs.

Adolescent body dissatisfaction and disordered eating: Predictors of later risky health behaviours.

RATIONALE: Body dissatisfaction is prevalent among teenagers, and may influence the uptake of risky health behaviours. OBJECTIVE: The study assessed the influence of body dissatisfaction on smoking, cannabis use, drug use, self-harm, gambling, and drinking and the mediating role of disordered eating in a population-based sample of British adolescents. METHOD: Participants were 2634 females and 1684 males from the Avon Longitudinal Study of Parents and Children (ALSPAC) cohort. Logistic regression was used to test if body dissatisfaction at 14 years old predicted the onset of risky health beh…

Навязчивое сексуальное поведение при навязчивом-компульсивном расстройстве: распространенность и связанная с этим комординация

В МКБ-11 будет включено нарушение сексуального поведения (CSBD) в качестве расстройства импульсного контроля. CSBD также имеет клинические особенности, связанные с навязчиво-компульсивными расстройствами спектра (OSDS) и поведенческими зависимостью. Было проведено относительно небольшое систематическое расследование ОСБД в связи с навязчиво-компульсивным расстройством (ОБД), которое является парадигматическим компульсивным расстройством. Мы поставили перед собой цель определить распространенность ОСБД в ОКР и связанные с этим социально-демографические и клинические особенности, включая связанн

Совпадение в аннотации оригинала
BACKGROUND AND AIMS: Compulsive sexual behavior disorder (CSBD) will be included in ICD-11 as an impulse-control disorder. CSBD also shares … erview for OCSDs was used to diagnose OCSDs (Tourette's syndrome, compulsive shopping, pathological gambling, kleptomania, pyromania, intermittent explosive disorder, self-injurious behavior, and CSBD). Prevalence rates of OCSDs in male versus female patients as well as comorbid disorders in OCD patients with and without CSBD were compared. RESULTS: Lifet …

Impulsivity and decision-making in obsessive-compulsive disorder after effective deep brain stimulation or treatment as usual.

OBJECTIVE: Impulsivity and impaired decision-making have been proposed as obsessive-compulsive disorder (OCD) endophenotypes, running in OCD … ), and healthy controls. METHODS: We used decision-making performances under ambiguity on the Iowa Gambling Task and reflection impulsivity on the Beads Task to compare 20 OCD patients effectively treated with vALIC-DBS, 40 matched OCD patients undergoing effective TAU (medication and/or cognitive behavioural therapy), and 40 healthy subjects. Effective t …

Prescription opioid medication misuse among university students.

BACKGROUND AND OBJECTIVES: Prescription opioid misuse is an established problem in the United States. Less information is known regarding th … stions regarding impulsivity, mental health, substance use, and other impulsive behaviors including gambling and sexual activity. 3,522 students completed the survey and were included in the analysis. RESULTS: Of this group, 2.2% reported misusing prescription opioids in the last 12 months and another 5.3% reported misusing prescription opioids previously …

Effects of neuromodulation on cognitive performance in individuals exhibiting addictive behaviors: A systematic review.

BACKGROUND: There is growing interest in non-invasive brain stimulation techniques as treatments for addictive disorders. While multiple rev … rticipants reporting substance use (e.g., alcohol, tobacco, or drugs) or addictive behaviors (e.g., gambling). Tasks were organized into five domains: (1) Inhibitory control, (2) Risk-taking, (3) Impulsive choice (delay discounting), (4) Executive function, and (5) Implicit biases. RESULTS: Twenty-four articles met the inclusion criteria. Fifty-seven perc …

Executive function impairments in fibromyalgia syndrome: Relevance of clinical variables and body mass index.

BACKGROUND: Several investigations suggest the presence of deterioration of executive function in fibromyalgia syndrome (FMS). The study qua … arch Test and the Zoo Map Task. Moreover, patients exhibited less steep learning curves on the Iowa Gambling Task. Among clinical variables, BMI and pain severity explained the largest proportion of performance variance. CONCLUSIONS: This study demonstrated impairments in executive functions of updating, shifting inhibition, decision making and planning i …

Neurocognitive correlates of medication-induced addictive behaviours in Parkinson's disease: A systematic review.

Dopaminergic medication can induce severe addictive behaviours (e.g., pathological gambling) in susceptible Parkinson's disease (PD) patients. It is still unknown which particular neurocognitive processes become exacerbated or dysfunctional in PD patients with addictive behaviours. We sought to systematically review the relevant literature to identity potential neurocognitive correlates of medication-induced addictive behaviours in PD. We framed our review around neurocognitive processes central to four dominant accounts of substance addiction: 'aberrant learning', 'incentive sensitization', '…

Blockade of dopamine D1-family receptors attenuates the mania-like hyperactive, risk-preferring, and high motivation behavioral profile of mice with low dopamine transporter levels.

BACKGROUND: Patients with bipolar disorder mania exhibit poor cognition, impulsivity, risk-taking, and goal-directed activity that negativel … amine transporter knockdown and wild-type littermate mice were tested in mouse versions of the Iowa Gambling Task (risk-taking), Progressive Ratio Breakpoint Test (effortful motivation), and Behavioral Pattern Monitor (activity). Prior to testing, the mice were treated with the dopamine D1-family receptor antagonist SCH 23390 hydrochloride (0.03, 0.1, or 0 …

Decision making under risk and under ambiguity in depressed suicide attempters, depressed non-attempters and healthy controls.

BACKGROUND: A number of neuropsychological alterations have been found in patients who have attempted suicide. Most studies investigating de … two tasks for the assessment of DM. The Game of Dice Task (GDT) measures DM under risk and the Iowa Gambling Task (IGT) DM under ambiguity. Further, depression severity, impulsiveness and suicidal intent of the current suicide attempt were assessed. RESULTS: Both depressed groups differed from controls with respect to marital and partnership status, smoki …

Impulse control behaviors and subthalamic deep brain stimulation in Parkinson disease.

To determine the clinical and demographic correlates of persistent, remitting, and new-onset impulse control behaviors (ICBs) before and aft … om 17.3 to 12.7 %; p = 0.095) with significant improvement in hypersexuality (12-8.0 %; p = 0.047), gambling (10.7-5.3 %; p = 0.033), and DDS (4.7-0 %; p < 0.001). ICB remitted in 18/26 patients (69 %) and persisted in 8/26 (31 %); the latter group was characterized by higher levodopa equivalent daily dose. Patients who developed a new-onset ICB during fol …

Co-occurring substance-related and behavioral addiction problems: A person-centered, lay epidemiology approach.

Background and aims The aims of this study were (a) to describe the prevalence of single versus multiple addiction problems in a large representative sample and (b) to identify distinct subgroups of people experiencing substance-related and behavioral addiction problems. Methods A random sample of 6,000 respondents from Alberta, Canada, completed survey items assessing self-attributed problems experienced in the past year with four substances (alcohol, tobacco, marijuana, and cocaine) and six behaviors (gambling, eating, shopping, sex, video gaming, and work). Hierarchical cluster analyses wer…

Impulsivity, Sensation Seeking, and Risk-Taking Behaviors among HIV-Positive and HIV-Negative Heroin Dependent Persons.

Objective. The aim of this study was to compare impulsivity and risky decision making among HIV-positive and negative heroin dependent persons. Methods. We compared different dimensions of impulsivity and risky decision making in two groups of 60 HIV-positive and 60 HIV-negative male heroin dependent persons. Each group was comprised of equal numbers of current (treatment seeker) and former (abstinent) heroin addicts. Data collection tools included Balloon Analogue Risk Task (BART), Iowa Gambling Task (IGT), Barratt Impulsiveness Scale (BIS), and Zuckerman Sensation Seeking Scale (SSS). Result…

Hot and cold executive functions in pure opioid users undergoing methadone maintenance treatment: Effects of methadone dose, treatment duration, and time between last methadone administration and testing.

CONTEXT: Methadone maintenance is a standard treatment for opiate-dependent individuals. However, deficits in cognitive functioning have bee … executive functions including decision-making and emotion recognition were assessed using the Iowa gambling task and Ekman faces test, whereas cold executive functions including working memory (WM), cognitive flexibility, and response inhibition were assessed using n-back, Wisconsin card sorting test, and the GO/NOGO task, respectively. Statistical Analys …