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[Clinical efficacy of posterior percutaneous endoscopic cervical discectomy for single level cervical spondylopathy with intraspinal ossification].

OBJECTIVE: To evaluate the effectiveness and security of posterior percutaneous endoscopic cervical discectomy (PPECD) in the treatment of s … ding to the characteristics of ossification, 17 cases were osteophytes on the posterior edge of the vertebral body;3 cases were protrusion ossification;3 cases were posterior longitudinal ligament ossification. According to the position of ossification in spinal canal, 14 cases were medial and lateral type, 5 cases were central type, and 4 cases were mixed type. …

Various Approaches to Open Removal of Inferior Vena Cava Filters.

BACKGROUND: Inferior vena cava (IVC) filters may lead to complications of IVC filter placement including strut migration and caval erosion i … ue to erosion into the duodenum. One patient presented with back pain due to strut erosion into the vertebral body. One patient presented with abdominal and back pain due to erosion into the duodenum, aorta, and vertebral body, and one patient presented with chest pain due to strut migration and perforation of the left ventricular wall with development of perica …

[Surgical treatment of atypical unstable Hangman fracture in elderly osteoporotic patients].

OBJECTIVE: To explore the clinical effect of operative reduction and internal fixation in treating atypical unstable Hangman fracture in eld … line was located at the pedicle of the axis, transverse foramen and posterior inferior wall of the vertebral body, accompanying by anterior and posterior longitudinal ligaments and C₂-C₃ intervertebral disc injury resulted in C₂-C₃ intervertebral instability in 2 cases. According to ASIA grade of spinal cord injury, 2 cases were grade D and 7 cases were grade E …

Treatment of thoracolumbar burst fractures by short-segment pedicle screw fixation using a combination of two additional pedicle screws and vertebroplasty at the level of the fracture: a finite element analysis.

BACKGROUND: Traditional one-above and one-below four-screw posterior short-segment instrumentation is used for unstable thoracolumbar burst … tress was concentrated at the crosslink and rod junctions. Maximal von Mises stress on the superior vertebral body for all loading conditions was larger than that on the inferior vertebral body. The maximal von Mises stress of the pedicle screws during all states of motion were 265.3 MPa in S-L fixation, 192.9 MPa in S-I fixation, 258.4 MPa in S-L-C fixation, an …

Which patients risk segmental kyphosis after short segment thoracolumbar fracture fixation with intermediate screws?

INTRODUCTION: The use of intermediate screws in fractured vertebrae has been proposed to decrease the number of fused levels in thoracolumba … rs included segmental kyphosis (SK), vertebral wedge angle (VWA) and loss of anterior and posterior vertebral body height. Patients were evaluated up to one-year follow-up. The correlation between LKC and potential risk factors, such as smoking habit, sex, age, neurological status and BMI was evaluated. RESULTS: Mean preoperative SK was 16.5°±6.5°, and it decre …

Role of Percutaneous Image Guided Biopsy in Spinal Lesions: Adequacy and Correlation with MRI Findings.

INTRODUCTION: Although, MRI has increased our understanding of spinal pathologies, accurate diagnosis of spinal lesions need biopsy, so that … Logistic regression analysis showed good correlation between malignancy and posterior bugle in the vertebral body in the absence of a fracture (p = 0.007), involvement of pedicles and posterior elements (p = 0.001) and soft tissue extension (p = 0.002); there was good correlation between infection and epidural abscess (p<0.001) as well as paradiscal involvement …

Vertebroplasty and kyphoplasty for the treatment of vertebral compression fractures: an evidenced-based review of the literature.

BACKGROUND: Vertebroplasty (VP) and kyphoplasty (KP) are routinely used to treat vertebral body compression fractures (VCFs) resulting from osteoporosis or vertebral body tumors in order to provide rapid pain relief. However, it remains debated whether VP or KP results in superior outcomes versus medical management alone in patients experiencing VCFs. PURPOSE: To determine the level of evidence supporting VP or KP for the treatment of VCFs. STUDY DESIGN: Systematic review of the literature. PATIENT SAMPLE: Patients with osteoporotic or tumor-associated VCFs. OUTCOME MEASURES: Self-reported…

[Clinical diagnosis and treatment of multiple level thoracolumbar spinal fractures].

OBJECTIVE: To investigate the clinical characteristics and methods of diagnosis and treatment multiple level thoracolumbar spinal fractures. … B, 2 of grade C, 5 of grade and 8 of grade E. The preoperative height of the anterior border of the vertebral body was (20.8 +/- 3.8) mm and the preoperative kyphosis angle was (16.2 +/- 3.4) degrees. All the unstable fractures were performed operation. Sixteen injured vertebras were treated with long-segment pedicle screw internal fixation; 8 were treated with …

2008 Young Investigator Award: The role of congenitally fused cervical segments upon the space available for the cord and associated symptoms in Klippel-Feil patients.

STUDY DESIGN: A prospective radiographic and retrospective clinical chart review. OBJECTIVE: This study evaluated the role of congenitally … on plain radiographs, assessment of the SAC consisted of the posterior atlantodens interval, the midvertebral body SAC (C2-C7), and the interbody SAC (C2-C3-C7-T1). Vertebral body width (VBW) from C2 to C7 and the presence of occipitalization (O-C1) were also noted. Torg ratios were obtained at each level. Demographics, medical history, and the presence of CSS w …

Pedicle screw fixation enhances anterior lumbar interbody fusion with porous tantalum cages: an experimental study in pigs.

STUDY DESIGN: A porous tantalum implant (Hedrocel, Implex Corp., Allendale, NJ), designed to assist interbody lumbar fusion, was tested biol … e marrow space in the center of a PT-ring was not significantly different from that of its adjacent vertebral body, but PSF increased bone marrow and decreased fibrous tissue formation in a tantalum cage. However, a CF-cage had higher bone volume and lower bone marrow space inside the cage compared with its adjacent vertebral body (P < 0.001). Fibrous tissue for …

Seasonal and sex differences in responsiveness to adrenocorticotropic hormone contribute to stress response plasticity in red-sided garter snakes (Thamnophis sirtalis parietalis).

As in many vertebrates, hormonal responses to stress vary seasonally in red-sided garter snakes (Thamnophis sirtalis parietalis). For example, males generally exhibit reduced glucocorticoid responses to a standard stressor during the spring mating season. We asked whether variation in adrenal sensitivity to adrenocorticotropic hormone (ACTH) explains why glucocorticoid responses to capture stress vary with sex, season and body condition in red-sided garter snakes. We measured glucocorticoids at 0, 1 and 4 h after injection with ACTH (0.1 IU g(-1)body mass) or vehicle in males and females durin

Appendage-resident epithelial cells expedite wound healing response in adult zebrafish.

Adult zebrafish are able to heal large-sized cutaneous wounds in hours with little to no scarring. This rapid re-epithelialization is crucial for preventing infection and jumpstarting the subsequent regeneration of damaged tissues. Despite significant progress in understanding this process, it remains unclear how vast numbers of epithelial cells are orchestrated on an organismic scale to ensure the timely closure of millimeter-sized wounds. Here, we report an unexpected role of adult zebrafish appendages (fins) in accelerating the re-epithelialization process. Through whole-body monitoring of

[Radiological and surgical characteristics of a case of recurring spinal hydatidosis].

INTRODUCTION: Hydatidosis is an illness that is still to be found in our setting. The lungs and liver are the organs most frequently involved and it rarely extends to bones. Involvement of the spine is infrequent, but it can give rise to a high degree of disability and may recur despite apparently complete excision. Here we report a case of recurring spinal hydatidosis with radiological and surgical particularities. CASE REPORT: Our case involves a 63-year-old male living in a rural area of the northern part of Spain's central plateau. The patient had a history of surgery for spinal hydatidos

Coprophagy Couples Hindgut Fermentation with Multi-Site Microbial Organization in Brandt's Vole.

Coprophagy, the ingestion of feces, is widespread among vertebrates and plays an important role in hindgut-fermenting herbivores by facilitating nutrient recycling and maintaining gut microbial stability. However, most studies have focused on cecal or fecal microbiota, with limited attention to microbial communities at other body sites. Here, we used Brandt's vole, a species exhibiting frequent coprophagic behavior, to examine how coprophagy prevention affects hindgut fermentation and microbial communities across multiple sites, including the tongue, lung, stomach, and cecum. Coprophagy preven

A large new Middle Jurassic ichthyosaur shows the importance of body size evolution in the origin of the Ophthalmosauria.

The Middle Jurassic is an important time period for the evolutionary history of marine reptiles as it represented a transitional phase for many clades. Notably, in ichthyosaurs, many early parvipelvian taxa went extinct. The Middle Jurassic saw the emergence of the derived Ophthalmosauria, ultimately becoming the dominant ichthyosaurian clade by the end of the epoch. Even though this is an important period in the evolutionary history of Ophthalmosauria, our understanding remains limited in terms of morphology and taxonomy due to the scarcity of vertebrate-bearing strata. Here we present a larg

Whole-body magnetic resonance imaging (WBMRI) versus whole-body computed tomography (WBCT) for myeloma imaging and staging.

Myeloma-associated bone disease (MBD) develops in about 80-90% of patients and severely affects their quality of life, as it accounts for the majority of mortality and morbidity. Imaging in multiple myeloma (MM) and MBD is of utmost importance in order to detect bone and bone marrow lesions as well as extraosseous soft-tissue masses and complications before the initiation of treatment. It is required for determination of the stage of disease and aids in the assessment of treatment response. Whole-body low-dose computed tomography (WBLDCT) is the key modality to establish the initial diagnosis

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… Fig. 3 ( a ) Marked osteolytic lesions are detected in the 6th, 7th and 11th thoracic vertebral body and pathological fractures in the 7th and 11th vertebrae in the sagittal CT reconstruction of the spine in the bone window. Additional lesions are suspected in the 8th–10th vertebral body. … The corresponding sagittal T1w MRI scan ( b ) and the STIR sequence ( c ) illustrate that every vertebral body is affected by myeloma Fig. 6 MRI illustration of a diffuse medullary infiltration pattern in myeloma using T1w ( a ) and STIR ( b ) sequences. …

Sall4 regulates neuromesodermal progenitors and their descendants during body elongation in mouse embryos.

Bi-potential neuromesodermal progenitors (NMPs) produce both neural and paraxial mesodermal progenitors in the trunk and tail during vertebrate body elongation. We show that Sall4, a pluripotency-related transcription factor gene, has multiple roles in regulating NMPs and their descendants in post-gastrulation mouse embryos. Sall4 deletion using TCre caused body/tail truncation, reminiscent of early depletion of NMPs, suggesting a role of Sall4 in NMP maintenance. This phenotype became significant at the time of the trunk-to-tail transition, suggesting that Sall4 maintenance of NMPs enables ta

Persistence of sodium monofluoroacetate in livestock animals and risk to humans.

1. Sodium monofluoroacetate (1080), a vertebrate pesticide widely used in New Zealand, was administered orally to sheep and goats at a dose level of 0.1 mg kg-1 body weight to assess risk to humans of secondary poisoning from meat. Blood, muscle, liver, and kidney were analysed for 1080 residues. 2. The plasma elimination half-life was 10.8 h in sheep and 5.4 h in goats. Concentrations of 1080 in muscle (0.042 microgram g-1), kidney (0.057 microgram g-1), and liver (0.021 microgram g-1) were substantially lower than those in plasma (0.098 microgram ml-1) at 2.5 h after dosing. 3. Only traces o

Atypical and less-common imaging presentations of chronic nonbacterial osteitis in children: a pictorial review.

Chronic nonbacterial osteitis (CNO), including its multifocal form, chronic recurrent multifocal osteomyelitis (CRMO), is an autoinflammatory sterile bone disorder with protean imaging features across the appendicular and axial skeletons in children and adolescents. Magnetic resonance imaging (MRI)-particularly whole-body MRI (WBMRI)-is pivotal for diagnostic imaging, mapping total inflammatory burden, demonstrating multifocality, and monitoring treatment response. Radiographs are frequently normal early in the disease. Beyond the classic metaphyseal pattern, we demonstrate atypical presentati

The tack technique for robotic ventral mesh rectopexy: An useful, safe and effective trick using the Hugo RAS™ system.

TECHNIQUE: We describe our standardized technique for mesh fixation during robotic ventral rectopexy performed with the Hugo RAS™ system. A non-absorbable helical tack device, introduced by the assistant through a robotic trocar, is used to secure the mesh to the anterior surface of the S1 vertebral body. Particular attention is paid to the preservation of critical anatomical structures, including the hypogastric nerves and sacral foramina. This approach, widely adopted in conventional laparoscopy, is reproducible and feasible in the robotic setting with the Hugo RAS™ platform. The system's op…