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Microbiology of surgical site infections complicating breast surgery.

BACKGROUND: Surgical site infection (SSI) rates complicating breast surgery have ranged from 1-26%, but limited data have been provided regarding pathogen identification and in vitro susceptibility results. The aim of this study was to evaluate the results of bacterial cultures of breast SSI sites and antibiotic susceptibility testing to determine the clinical utility of these findings. STUDY DESIGN: Medical records were reviewed for SSI in patients who had undergone breast/axillary surgical procedures between June 2003 and June 2006. An SSI was defined by the criteria of the U.S. Centers for

Rifaximin: a nonsystemic rifamycin antibiotic for gastrointestinal infections.

Use of nonsystemic antimicrobials with activity against enteropathogens is a promising approach for treatment of infectious diarrhea and other nonsystemic gastrointestinal infections. Rifaximin is approved by the US FDA for the treatment of travelers' diarrhea caused by noninvasive strains of Escherichia coli in patients aged 12 years and older, and for the reduction in risk of overt hepatic encephalopathy (HE) recurrence in patients aged 18 years or older. Rifaximin has been available in Italy since 1987 and overall is approved in 33 countries for various conditions, such as acute and chronic…

[Fungal infections in oncohematology: the role of prophylaxis].

Angiectatic nasal polyps (ANP) are rare pseudo-neoplastic lesions that might raise intriguing pathophysiological issues and present a significant diagnostic challenge. They are also referred to as inflammatory granuloma telangiectaticum, vascular granuloma, pseudo-angioma, and angiomatous/angiectatic polyp. However, the name angiectatic polyp refers to the fact that the lesion is not a true tumour and is clinically distinguished by ectatic vasculature, haemorrhage, and persistent proliferation. The most confusing aspect of this polyp is its clinical appearance, which resembles a juvenile nasal

Pneumococcal infections in high-risk and immunocompromised hosts.

Streptococcus pneumoniae is an important cause of morbidity and mortality worldwide, it is responsible for invasive pneumococcal disease (IP … (specific and innate), genetic and environment. Specific defects in host responses to pneumococcal infections may due to very young age, deficiencies in levels of antibodies and complement factors, and splenic dysfunction. The combinations of these defects contribute to the increased rates of IPD. The immunocompromising and other conditions that predispose …

Adenovirus infections in pediatric small bowel transplant recipients.

BACKGROUND: Adenovirus is commonly isolated from pediatric small bowel transplant recipients, but its clinical consequences remain poorly un … nts were included; 38 were positive for adenovirus (incidence 23.5%), 23 for viral shedding, 23 for infections. Nine infections developed in the first month after transplantation and 8 during the following 5 months. The small bowel was involved in 19 cases. Younger age at transplantation was a risk factor for adenovirus infection (odds ratio=0.81, 95% confid …

[Histopathology of the more common viral skin infections].

We describe the histopathological characteristics of viral skin infections. Herpes simplex virus and varicella-zoster virus produce an intraepidermal vesicle with variable degrees of epithelial necrosis. Typical findings include keratinocytes with ballooned nuclei with a ground-glass appearance and giant multinucleated keratinocytes. In the endothelial cells of the dermal blood vessels, cytomegalovirus produces large eosinophilic nuclear inclusions surrounded by a clear halo. Human herpes virus 8 is etiologically associated with Kaposi sarcoma. In its early stages, this tumor contains blood ve…

Острые арбовирусные инфекции в Гвинее, Западная Африка, 2006 год.

Острые желудочно-кишечные заболевания составляют бóльшую часть человеческого бремени в странах Африки к югу от Сахары. Мы предположили, что арбовирусы составляют значительную долю не диагностированных фебрильных заболеваний в Гвинее, и попытались определить частоту заболевания арбовирусами в двух больницах. С использованием стандартного определения случая примерно за 4 месяца было выявлено 47 подозрительных случаев. Анализы иммуноглобулина M против антител, связанные с иммуносорбентом, и нейтрализация табло показали, что 63% (30/47) пациентов были заражены арбовирусами, в том числе 11 - Западн

Совпадение в аннотации оригинала
Acute febrile illnesses comprise the majority of the human disease burden in sub-Saharan Africa. We hypothesized that arboviruses comprised … ted with arboviruses, including 11 West Nile, 2 yellow fever, 1 dengue, 8 chikungunya, and 5 Tahyna infections. Except for yellow fever, these are the first reported cases of human disease from these viruses in Guinea and the first reported cases of symptomatic Tahyna infection in Africa. These results strongly suggest that arboviruses circulate and are comm …

Disease burden of Puumala virus infections, 1995-2008.

Puumala virus (PUUV) causes mild haemorrhagic fever with renal syndrome, a rodent-borne zoonosis. To evaluate the disease burden of PUUV infections in Finland, we analysed data reported by laboratories to the National Infectious Disease Registry during 1995-2008 and compared these with data from other national registries (death, 1998-2007; hospital discharge, 1996-2007; occupational diseases, 1995-2006). A total of 22,681 cases were reported (average annual incidence 31/100,000 population); 85% were in persons aged 20-64 years and 62% were males. There was an increasing trend in incidence, and…

[Modified classification of microscopic evaluation of vulvovaginal infections].

OBJECTIVE: The objective of the study is to examine the role of microscopy using stained smears for diagnosis of vulvovavaginal infections: DESIGN: Description of different scoring systems. SETTINGS: Department of Gynecology and Obstetrics, First Medical Faculty, Charles University; General Teaching Hospital, Prague; Institute of Clinical Chemistry and Laboratory Medicine; Clinical Microbiology and Antibiotic Center, First Medical Faculty, Charles University. MATERIAL AND METHODS: Presentation of our practical skills in microscopic diagnoses of vulvovaginal infections. CONCLUSIONS: Vulvova…

Surgical management of diabetic foot and ankle infections.

Delayed treatment of any diabetic foot infection can lead to a limb- or life-threatening scenario. Urgent and/or emergent surgery may be necessary in the early diagnosis of a severe diabetic foot infection that is followed by staged reconstructive procedures. This article provides the reader with a thorough understanding of the surgical management of severe diabetic foot infections and describes and guides treatment based on a rational schematic approach that identifies the anatomic location of the diabetic foot infection.

Contemporary management of cardiovascular implantable electronic device infections.

Cardiovascular implantable electronic device (CIED) implantation rate has substantially risen in the foregoing decades. Unfortunately, this upsurge in CIED implantation rate has been accompanied by a disproportionate rise in the rate of CIED infections. Device infection is a major complication of CIED implantation, necessitating removal of an infected device followed by systemic antimicrobial therapy and reimplantation of a new system. In this article, we review the current epidemiology, risk factors, diagnostic strategy and contemporary management of CIED infection. In addition, we address th…

[Update on current care guidelines. Bacterial skin infections].

Bacterial skin infections are common, and range from mild to serious, even life-threatening infections. This guideline presents treatment options for erysipelas, cellulitis, impetigo, ecthyma, folliculitis, abscess, paronychia (nail infection) and early borreliosis as well as for erysipeloid, mycobacterial skin infections and tularemia. Recommended antibiotic and/or other treatments are described for children and adults.

[Foodborne infections and intoxications in Poland in 2008].

A total of 12 217 bacterial foodborne infections and intoxications were registered in 2008 (incidence 32.1/100 000 population). Unlike bacterial infections, the incidence of viral foodborne infections increased in the recent years (2008 - 85.4 vs. 2007 - 57.1; 2006 - 54.21; 2005 - 32.8, and median 2002-2006 - 27.2). In 2008 were notify of 480 foodborne infections and intoxications involving 5788 cases (only outbreaks involving 4 person or more) and 138 foodborne (involving 2-3 persons). S. Enteritidis were the most frequency etiological agent in outbreaks (94.2% of outbreaks 89.3% cases in out…

[Retro- and parapharyngeal infections: standardization of their management].

AIM: To analyze the changes in the management of retropharyngeal and parapharyngeal infections and propose a decisional algorithm for their diagnosis and treatment. PATIENTS AND METHODS: A retrospective survey was carried out in a tertiary care pediatric hospital between January 2001 and December 2005. All children aged less than 15 years and affected by a retro- or parapharyngeal infection were included. Clinical, biological, and radiological data, medical and surgical treatment, and complications were extracted from the review of medical charts. The results of the surgical findings were cor…

Human dectin-1 deficiency and mucocutaneous fungal infections.

Mucocutaneous fungal infections are typically found in patients who have no known immune defects. We describe a family in which four women who were affected by either recurrent vulvovaginal candidiasis or onychomycosis had the early-stop-codon mutation Tyr238X in the beta-glucan receptor dectin-1. The mutated form of dectin-1 was poorly expressed, did not mediate beta-glucan binding, and led to defective production of cytokines (interleukin-17, tumor necrosis factor, and interleukin-6) after stimulation with beta-glucan or Candida albicans. In contrast, fungal phagocytosis and fungal killing w…

Pulmonary nontuberculous mycobacterial infections in hyper-IgE syndrome.

Patients with Hyper Immunoglobulin E Syndrome are predisposed to infections with nontuberculous mycobacteria (NTM) as bronchiectasis develops. Pulmonary NTM infection should be aggressively looked for and treated in these patients.

Timing and impact of infections in acute pancreatitis.

BACKGROUND: Although infected necrosis is an established cause of death in acute pancreatitis, the impact of bacteraemia and pneumonia is le … ds ratio (OR) 18.0), bacteraemia (OR 3.4) and age (OR 1.1) were associated with death. CONCLUSION: Infections occur early in acute pancreatitis, and have a significant impact on mortality, especially bacteraemia. Prophylactic strategies should focus on early intervention.

[An overview of Strongyloides stercoralis and its infections].

Strongyloidiasis which is an infection caused by Strongyloides stercoralis, has a cosmopolitan distribution in tropical and subtropical regions; whereas, it is sporadic in Turkey. It is estimated that 30-100 million people are infected with this agent worldwide. The infection is usually asymptomatic, however, eosinophilia may be the only sign. S. stercoralis have the ability to persist and replicate within the host for decades and it may lead to infections with high mortality especially in immunocompromised host. Humans are generally infected transcutaneously with filariform larvae. Infections…