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Prevalence and risk factors of kidney stone disease in population aged 40-70 years old in Kharameh cohort study: a cross-sectional population-based study in southern Iran.

BACKGROUND: Kidney stone is the major cause of morbidity, and its prevalence is increasing in the world. This study aimed to assess the prevalence and risk factors of kidney stone in the adult population of southern Iran based on the data of the Kharameh Cohort Study. METHODS: This cross-sectional study was conducted on 10,663 individuals aged 40-70 years old, using the baseline data of Kharamah cohort study, which started in 2014. Among all participants, 2251 individuals had a history of kidney stone. The participants' demographic characteristics, behavioral habits, and the history of underl…

Frequency of DNA gyrase and topoisomerase IV mutations and plasmid-mediated quinolone resistance genes among Escherichia coli and Klebsiella pneumoniae isolated from urinary tract infections in Azerbaijan, Iran.

OBJECTIVES: This study assessed genetic alterations in gyrA, gyrB, parC and parE and the prevalence of plasmid-mediated quinolone resistance (PMQR) genes among Escherichia coli and Klebsiella pneumoniae isolates from urinary tract infections (UTIs) in Azerbaijan, Iran. METHODS: A total of 205 clinical isolates of E. coli (n=177) and K. pneumoniae (n=28) were obtained from UTIs. Antimicrobial susceptibility was determined by disk diffusion and agar dilution assays. The presence of PMQR genes was determined by PCR, and sequencing of the gyrA, gyrB, parC and parE was performed. RESULTS: The rat…

Comparison of immunofluorescence and enzyme-linked immunosorbent assay and immunoglobulin G avidity techniques for screening of anti: Toxoplasma antibodies among single serum sample pregnant women in Tabriz, Iran.

BACKGROUND: Congenital toxoplasmosis is that pregnant women acquire the infection during gestation; diagnosis of the acute infection during pregnancy is a complex subject of maternal toxoplasmosis. Thus, the presence of immunoglobulin G (IgG) and/or IgM Toxoplasma antibodies in a single serum sample drawn during gestation cannot be used to define whether the infection was recently acquired or chronic. MATERIALS AND METHODS: At this cross-sectional descriptive study, sera of 391 pregnant women examined and compared. They were in an age range of 21-35 years, referred by gynecologists and infect

Awareness and Acceptance of the Human Papillomavirus (HPV) Vaccine and Associated Factors Among Parents of Adolescents (9-18 Years) at a Children's Hospital in Babol, Iran: A Cross-Sectional Study.

BACKGROUND AND AIMS: High-risk human papillomavirus (HPV) infection is a major cause of cervical and other anogenital cancers, and vaccination is an effective preventive strategy when administered during adolescence. Because parental decision-making plays a central role in adolescent vaccination uptake, this cross-sectional study aimed to assess parental awareness, attitudes, and barriers related to HPV infection and HPV vaccination, as well as demographic factors associated with vaccine awareness, among parents of adolescents attending a tertiary pediatric hospital in Babol, Iran. METHODS: I…

Rationale and Methods of a Surveillance System for Hematopoietic Stem Cell Transplantation in Patients With Hematological Malignancies: A Qualitative Participatory Action Research Approach in Middle-Income Countries-The Experience in Iran.

BACKGROUND AND AIMS: Hematopoietic Stem Cell Transplantation (HSCT) represents a cornerstone in the therapeutic management of hematological malignancies, aimed at achieving durable remission and enhancing survival. Optimal post-transplant care, however, necessitates access to near-real-time, actionable clinical data. Iran currently lacks a dedicated national surveillance framework for HSCT recipients. This study aims to develop and pilot a comprehensive surveillance system tailored to the complexities of HSCT within the Iranian healthcare context. METHODS: This qualitative Participatory Actio…

Clinical and laboratory findings in patients with castor bean (Ricinus communis L.) poisoning referred to Imam Reza hospital in northeast of Iran, from April 2015 to March 2020.

OBJECTIVE: Castor bean (CB) (Ricinus communis) contains a highly toxic natural compound called ricin. We retrospectively reviewed the documents of CB-poisoned cases referred to the clinical toxicology department of Imam Reza Hospital affiliated with Mashhad University of Medical Sciences, Mashhad, Iran. MATERIALS AND METHODS: Patients' data including epidemiological variables, rout and amount of CB ingestion, clinical and laboratory findings, and type of treatment were extracted from hospital documents. RESULTS: Twelve cases of CB ingestion, with mean age 29.42 ± 21.19 years (4 to 70 years),…

Prevalence and Determinants of Hospital-Acquired Infections in Intensive Care Units Before and After the COVID-19 Pandemic: A Retrospective Descriptive Surveillance Study at a Tertiary Care Hospital in Iran.

BACKGROUND AND AIMS: Hospital-acquired infections (HAIs) in intensive care units (ICUs) cause significant morbidity, mortality, and costs. The COVID-19 pandemic intensified infection control, but its effect on HAI prevalence and patterns is unclear. This study compared HAI prevalence, types, and causative agents in an Iranian tertiary hospital before and after COVID-19. METHODS: A retrospective descriptive-analytical study was conducted on ICU patients admitted to Taleghani Hospital, Kermanshah, Iran, between 2019 and 2020. Demographic, clinical, and microbiological data were collected from h…

Association of physical activity and nutrition-related knowledge, attitudes and practices with obesity indices in college-aged females with polycystic ovary syndrome in Shiraz, Iran: a cross-sectional study.

OBJECTIVE: Diet and physical activity modifications are prescribed to women with polycystic ovary syndrome (PCOS). This study aimed to evaluate the correlation between physical activity and nutrition-related knowledge, attitudes and practices with obesity indices in young women with PCOS. DESIGN: A cross-sectional study. SETTING: Universities located in Shiraz. PARTICIPANTS: 308 young college women (age: 21.51±0.82 years, body mass index (BMI): 23.78±4.36 kg/m2) with PCOS who studied in several universities in Shiraz from February to August 2023 participated in the study voluntarily. METHO

Enhancing Hepatitis B and C Prevention Among People Who Use Drugs: Evaluating an Educational Intervention at a Drop-In Center in Southwest Iran based on Protection Motivation Theory.

BACKGROUND: Substance abuse, particularly injection drug use, remains a significant public health challenge in Iran, where an estimated 2 million people use illicit drugs daily. Injection drug users are at high risk for bloodborne infections such as hepatitis B and C, which contribute substantially to morbidity and mortality in this population. Understanding individual factors that influence risky behaviors through frameworks like the Protection Motivation Theory (PMT) is essential for effective prevention. This study aimed to assess the impact of a PMT-based educational intervention on reduci…

The effect of Trehalose on inflammatory markers, oxidative stress, clinical symptoms, and mortality in patients with head trauma in Iran: a double-blind, placebo-controlled, randomized clinical trial protocol.

BACKGROUND: The occurrence of traumatic brain injury (TBI) has been progressively increasing over the years, mainly due to factors such as d … ed trial, we will recruit 80 patients aged 18 to 65 years with TBI from Al-Zahra Hospital, Isfahan, Iran, and randomly allocate them at the individual level into two groups of 40. One group will receive 10 g of trehalose daily (intervention group), while the other will receive 10 g of maltodextrin (placebo group) for 7 days. Primary outcomes include in …

The national and subnational burden of falls and its attributable risk factors among older adults in Iran from 1990 to 2021: findings from the global burden of disease study.

BACKGROUND: Falls among older adults (individuals aged 60 and above) are a substantial health issue worldwide. This study aimed to analyze the burden of falls and its attributable risk factors among older adults at the national and subnational levels in Iran over 32 years. METHODS: Using the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2021 data, we estimated the incidence, prevalence, death, and disability-adjusted life-years (DALYs) of falls and its attributable risk factors among older adults by sex, age groups, and socio-demographic index (SDI) in Iran and its provinc…

Временная тенденция изменения национального и субнационального бремени раковых заболеваний, обусловленная факторами риска в Иране 1990 в адрес 2021:: Результаты глобального исследования бремени болезней 2021.

Рак является одной из главных причин смерти в мире и в Иране. Однако исследований, посвященных изучению тенденций, связанных с факторами риска возникновения раковых заболеваний в Иране, недостаточно. В этом исследовании мы представляем оценки возможного воздействия раковых заболеваний на национальном и субнациональном уровнях в Иране. 1990 в адрес 2021. МЕТОДЫ: В рамках данного исследования использовались данные, полученные от Глобального центра по проблемам заболеваемости (ГБЗ) 2021 Исследование, проведенное для оценки потерянных лет жизни, связанных с раком, лет жизни с инвалидностью, лет жи

Совпадение в аннотации оригинала
BACKGROUND: Cancer is among leading causes of death globally and in Iran. However, studies exploring cancer risk factors trends in Iran are scarce. In this study, we provide estimations of risk-attributable cancer burden at the national and subnational levels in Iran from 1990 to 2021. METHODS: This study utilized data from the Global Burden of Disease (GBD…

The Prevalence and Risk Factors of Hepatitis B, Hepatitis C, and Hepatitis D Coinfection in Iran's General Population Over the Past 25 Years: A Systematic Review and Meta-Analysis.

Concurrent HBV, HCV, and HDV infections pose a global health challenge, worsening disease, treatment, and patient outcomes, and burdening healthcare. In Iran, no comprehensive review has assessed HBV/HCV and HBV/HDV coinfection rates. This study conducted a systematic review and meta-analysis per PRISMA 2020 guidelines. The study was prospectively registered in PROSPERO (CRD420251007210). A comprehensive search was conducted across international (PubMed, Scopus, Embase, Web of Science, Cochrane Library) and Iranian databases (SID, Magiran), supplemented by Google Scholar, for studies published…

Systematic review and meta-analysis on the prevalence of extended-spectrum β-lactamases-producing Acinetobacter baumannii in Iran: Evaluation of TEM, PER, SHV, CTX-M, VEB and GES.

Acinetobacter baumannii's resistance to antibiotics restricts treatment ways, and has enhanced its mortality rates approaching 35 %. Resistance to β-lactams in Acinetobacter baumannii, related to extended-spectrum β-lactamases (ESBLs), has become a worldwide concern. This study aimed to assess the prevalence of Extended-Spectrum Beta-Lactamase-Producing Acinetobacter baumannii in Iran. Important databases (PubMed, Scopus, Wily Online Library, ScienceDirect and Google Scholar) were searched for related literature published from January 2010 to April 2024. The inclusion criteria were predefined …

Population genetic structure and phylogenetic analysis of Anopheles hyrcanus (Diptera: Culicidae) inferred from DNA sequences of nuclear ITS2 and the mitochondrial COI gene in the northern part of Iran.

BACKGROUND: The Anopheles hyrcanus group is distributed throughout the Oriental and Palaearctic regions and can transmit diseases such as malaria, Japanese encephalitis virus, and filariasis. This investigation marks the inaugural comprehensive study to undertake a phylogenetic analysis of the constituents of this malaria vector group in the northeastern region of Iran, juxtaposed with documented occurrences from different areas within Iran and worldwide. METHODS: Mosquitoes were collected using various methods from nine different locations in Golestan province from April to December 2023. Th…

Headache following vaccination against COVID-19 among healthcare workers with a history of COVID-19 infection: a cross-sectional study in Iran with a meta-analytic review of the literature.

BACKGROUND: There is evidence of the occurrence of headache after vaccination against COVID-19. However, only a few studies have examined the headache characteristics and related determinants, especially among healthcare workers with a history of COVID-19 infection. METHODS: We evaluated the incidence of headaches after injection of different types of COVID-19 vaccine to determine factors relating to the incidence of headache after vaccination among the Iranian healthcare workers who had previously contracted COVID-19. A group of 334 healthcare workers with a history of COVID-19 infection wer…

Effect of CoQ10 Supplement on Spermogram Parameters and Sexual Function of Infertile Men Referred to The Infertility Center of Fatemieh Hospital, Hamadan, Iran, 2019: A Randomized Controlled Trial Study.

BACKGROUND: The aim of this study was to investigate the effects of the antioxidant supplement of CoQ10 and placebo in the male infertility treatment. MATERIALS AND METHODS: The randomized controlled trial study was designed as a clinical trial. Samples in each group consisted of 30 members. The first group received 1 daily dose of 100 mg coenzyme Q10 capsules and the second group received a placebo treatment. Treatment in both groups lasted 12 weeks. Before and after the intervention of semen analysis, hormonal measurement of testosterone, prolactin, luteinizing hormone (LH), follicle-stimul

Estimates of incidence, prevalence, mortality, and disability-adjusted life years of lung cancer in Iran, 1990-2019: A systematic analysis from the global burden of disease study 2019.

BACKGROUND: Lung cancer is one of the leading cancers, with a high burden worldwide. As a developing country, Iran is facing with population growth, widespread tobacco use, demographic and epidemiologic changes, and environmental exposures, which lead to cancers becoming a severe concern of public health in Iran. We aimed to examine the burden of lung cancer and its risk factors in Iran. METHODS: We utilized the Global Burden of Disease 2019 data and analyzed the total burden of the lung cancer and seven related risk factors by sex, age at national and sub-national levels from 1990 to 2019. …

A survey of prevalence and phenotypic and genotypic assessment of antibiotic resistance in Staphylococcus aureus bacteria isolated from ready-to-eat food samples collected from Tehran Province, Iran.

BACKGROUND: Resistant Staphylococcus aureus (S. aureus) bacteria are considered among the major causes of foodborne diseases. This survey aims to assess genotypic and phenotypic profiles of antibiotic resistance in S. aureus bacteria isolated from ready-to-eat food samples. METHODS: According to the previously reported prevalence of S. aureus in ready-to-eat food samples, a total of 415 ready-to-eat food samples were collected from Tehran province, Iran. S. aureus bacteria were identified using culture and biochemical tests. Besides, the phenotypic antibiotic resistance profile was determined…

Phylogenetic and molecular analysis based on genes 16S-rRNA, OMPA and POMP to identify Chlamydia abortus infection occurrence at the milk samples of goats and sheep in west Azerbaijan of Iran.

BACKGROUND AND OBJECTIVES: Enzootic abortion in sheep and goats, also called ovine enzootic abortion (OEA) or enzootic abortion of ewes (EAE … and POMP of C. abortus in milk samples collected from sheep and goats in West Azerbaijan province, Iran. During 2018, a total number of 360 milk samples were collected from sheep (n = 180) and goats (n = 180) of different regions of the province. All milk samples were subjected to DNA extraction and examined by PCR. RESULTS: Among 360 milk samples co …