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HIV prevalence among 338,432 infertile individuals in Hunan, China, 2012-2018: A cross-sectional study.

BACKGROUND: The prevalence of human immunodeficiency virus (HIV) varies markedly among different risk groups in China, spreading fromhigh-ri … prevalence of HIV/other infections (hepatitis B virus (HBV), hepatitis C virus (HCV), syphilis, and Chlamydia trachomatis, Neisseria gonorrhoeae, and Mycoplasma genitalium (MG) infections) among 338,432 infertile individuals in Hunan, China, from 2012 to 2018. We calculated linear trends in prevalence using bivariate linear regression. RESULTS: The overall prevalence …

Factors associated with sexually transmitted infection diagnosis in women who have sex with women, women who have sex with men and women who have sex with both.

INTRODUCTION: Many US women report same sex behaviour, yet data on risk factors and STIs in women who have sex with women (WSW), women who h … ing the χ2 test. Acute STI (aSTI) was defined as gonorrhoea (Neisseria gonorrhoeae, GC), chlamydia (Chlamydia trachomatis, CT), trichomonas (Trichomonas vaginalis, TV) or early syphilis. Logistic regression was used to assess aSTI predictors. CT testing was not uniformly done, so a sensitivity analysis removing CT from the aSTI definition was conducted. RESULTS: Visit …

Trends of bacterial sexually transmitted infections with doxycycline post-exposure prophylaxis among people using pre-exposure prophylaxis for HIV.

BACKGROUND: People using pre-exposure prophylaxis (PrEP) for HIV are at high risk of acquiring sexually transmitted infections (STIs). We aimed to assess the impact of doxycycline post-exposure prophylaxis (doxy-PEP) on the incidences of STIs among PrEP users in the real-world setting. METHODS: From February 2022 to November 2025, participants aged ≥18 years receiving HIV PrEP were prospectively enrolled. STI testing at baseline and follow-up included syphilis serology and multiplex real-time PCR assays for Chlamydia trachomatis, Neisseria gonorrhoeae and Mycoplasma genitalium. Beginning in N…

Combined Testing for Chlamydia, Gonorrhea, and Trichomonas by Use of the BD Max CT/GC/TV Assay with Genitourinary Specimen Types.

The BD Max CT/GC/TV (MAX) assay is a true multiplex assay for simultaneous detection of chlamydia (CT), gonorrhea (GC), and trichomonas (TV) … dia and gonorrhea infections, respectively, were identified. Comparator assays included BD ProbeTec Chlamydia trachomatis Qx (CTQ)/Neisseria gonorrhoeae Qx (GCQ), Hologic Aptima Combo 2 (AC2) and Aptima TV (ATV), trichomonas microscopy, and culture. MAX CT sensitivity was 99.3% (95% confidence interval [CI], 96.1% to 99.9%), 95.7% (90.8% to 98.0%), 91.5% (85.8% to 95.1 …

A microphysiologic human cervical model recapitulates microbial, immune, and pathogenic properties of sexually transmitted infections.

Sexually transmitted infections (STIs) of the cervicovaginal mucosa are among the most common global infections. Current monolayer cell culture and animal models fail to reproduce the multilevel complexity required to investigate host-microbiota-pathogen relationships simultaneously and/or with sufficient physiological relevance. To address this limitation, we have developed a microphysiologic system (MPS) that models human cervical tissue and its microbiota and is susceptible to infection by two prominent genital pathogens, Chlamydia trachomatis and Neisseria gonorrhoeae. Notably, this MPS pl…

Chlamydial and Gonococcal Infections and Adverse Reproductive Health Conditions Among Patients Assigned Female at Birth in the Veterans Health Administration.

BACKGROUND: Reproductive age female individuals comprise the fastest-growing segment of Veterans Health Administration patients, but little is known about rates of reproductive health outcomes among those with chlamydia or gonorrhea infections. Our aim was to estimate the risk of pelvic inflammatory disease, ectopic pregnancy, infertility, and pelvic pain in female veterans tested for chlamydia or gonorrhea. METHODS: We performed a retrospective cohort analysis of female veterans tested for chlamydia or gonorrhea between January 1, 2010, and December 31, 2020. We calculated rates of pelvic in

Overcoming analytical and preanalytical challenges associated with extragenital home collected STI specimens.

UNLABELLED: Home sample collection for sexually transmitted infection (STI) screening options can improve access to sexual healthcare across communities. For Chlamydia trachomatis (CT) and Neisseria gonorrhoeae (NG), genital infections have classically been the focus for remote collection options. However, infections may go undiagnosed if sampling is limited to urogenital sites because some individuals only participate in oral and/or anal intercourse. Here we evaluated samples for CT/NG detection after several pre-analytical collection challenges. A paired provider to self-collection validatio…

Expedited Partner Therapy in Female Adolescents: A Study of Acceptance and the Impact on Reinfection Rates.

BACKGROUND: Given the high risk of sexually transmitted infections (STIs) in adolescents and young adults (AYAs), this study evaluated expedited partner therapy (EPT) acceptance and STI reinfection rates in female AYA before and after availability of EPT. METHODS: The pre-EPT cohort was a 3-year (November 2012 to November 2015) retrospective chart review of female AYA positive for Chlamydia trachomatis (CT) and/or Trichomonas vaginalis (TV) before introduction of EPT. An EPT protocol for CT and TV infections was implemented after legalization in Ohio in 2016. The post-EPT cohort was a prospec…

High prevalence of rectal chlamydia among pregnant adolescents in La Romana, Dominican Republic warrants extragenital STI testing.

To our knowledge, there are no studies estimating the prevalence of extragenital sexually transmitted infections (STIs) among pregnant adolescents in the Caribbean. This study sought to fill this gap by assessing the prevalence and correlates of oral, genital, and rectal chlamydia (CT) among a sample of pregnant adolescents in La Romana, Dominican Republic. Two hundred pregnant youths, aged 15-24 years, were recruited by systematic sampling during their first prenatal visit to a maternal care unit. A sociodemographic and behavioral questionnaire was administered and urine and oral/anal swabs w

Drassanes Exprés: a public and confidential testing service for asymptomatic STIs with same-day result notification.

BACKGROUND: STIs are a major public health concern. Screening programmes for asymptomatic users are key components of STI control. Tradition … rs). Overall, 14.6% of users tested positive for at least one STI. The most prevalent infection was Chlamydia trachomatis (8.3%), followed by Neisseria gonorrhoeae (5.7%), syphilis (1.8%), HIV (0.4%) and hepatitis C virus (0.2%). The median time from test to results was 2.4 hours (range: 2-3.1 hours). Of 2049 users diagnosed with an STI, treatment was achieved in 97.0% …

Triple site sexually transmitted infection testing as a crucial component of surveillance for men who have sex with men: A prospective cohort study.

Chlamydia trachomatis (CT) and Neisseria gonorrhoeae (NG) infections are common among men who have sex with men (MSM). Many oropharyngeal and anorectal infections remain asymptomatic. We aimed to evaluate triple-site screening following PrEP introduction. We enrolled a prospective cohort study including 210 asymptomatic MSM during 2019-2020, analyzed by groups: HIV positive (HIV+), HIV-uninfected using PrEP (HIV-/PrEP+), or HIV-uninfected not using PrEP (HIV-/PrEP-). A self-administered questionnaire captured demographic information and sexual risk-taking behaviors. CT/NG testing results were …

Типы папилломавируса человека, наблюдаемого у госпитализированного населения.

ВАЖНЕЙШИЕ И ЗАДАЧИ: Папильомавирус человека (ВПЧ) является причиной рака шейки матки, одной из основных причин смертности от рака у индийских женщин. Нынешнее исследование было проведено для того, чтобы дополнить имеющиеся данные о распределении ВПЧ по типам в индейцах, с тем чтобы попытаться документально зафиксировать типы ВПВ для будущей программы вакцинации, если таковые имеются. МАТЕРИАЛЫ И МЕТОДЫ: В 223 случаях заболевания раком шейки матки и 2408 случаях заболевания здоровыми женщинами без рака и внутриэпифелевой неоплазией шейки матки (контроль). Велосипедная цепная реакция полимеразы,

Совпадение в аннотации оригинала
BACKGROUND AND OBJECTIVES: Human papillomavirus (HPV) is the causative agent of cervical cancer, a major cause of cancer mortality in Indian … rvical cancer. In control, 27.3% were co-infected with other sexually transmitted infections, while Chlamydia trachomatis infection was seen in 13% of cases. CONCLUSIONS: The study highlighted the type of HPV infection seen among the hospital-based population. For better screening, HPV tests available in the market should include all the types seen in the population.

Molecular point-of-care testing for chlamydia and gonorrhoea in Indigenous Australians attending remote primary health services (TTANGO): a cluster-randomised, controlled, crossover trial.

BACKGROUND: Timely diagnosis and treatment of sexually transmissible infections will prevent morbidity and onward transmission. We aimed to assess the efficacy of a point-of-care molecular test for Chlamydia trachomatis and Neisseria gonorrhoeae infections at the cluster level to improve infection management among Indigenous Australian communities with high prevalence of sexually transmissible infections. METHODS: In this cluster-randomised crossover study, we recruited primary health services in Western Australia, Far North Queensland, and South Australia that provide care to Indigenous peop…

[THE ROLE OF COLPOSCOPY AS A METHOD OF METHODOLOGY FOR EARLY AND RAPID ETIOLOGIC DIAGNOSIS IN THE STUDY OF ENDOCERVICITIS CHLAMYDIALIS.].

The aim of this study was: 1. To analyze and study the specifics of colposcopic picture of ecto-and endo-cervix in endocervicitis chlamydialis. 2. To demonstrate the leading role of colposcopy method as part of the methodology for early and rapid etiologic diagnosis of chlamydial cervicitis in order to conduct etriotropian treatment.Results 1. Determine the frequency of incidence of endocervicitis chlamydialis, to cause Chl.trachomatis 45,1%, (319 DIF(+) patients out of 708 surveyed), p <0.05 in the Ruse region. 2. Demonstrated statistically significant relationship between the incidence of en

Cost-Effectiveness of Opt-Out Chlamydia Testing for High-Risk Young Women in the U.S.

INTRODUCTION: In spite of chlamydia screening recommendations, U.S. testing coverage continues to be low. This study explored the cost-effectiveness of a patient-directed, universal, opportunistic Opt-Out Testing strategy (based on insurance coverage, healthcare utilization, and test acceptance probabilities) for all women aged 15-24 years compared with current Risk-Based Screening (30% coverage) from a societal perspective. METHODS: Based on insurance coverage (80%); healthcare utilization (83%); and test acceptance (75%), the proposed Opt-Out Testing strategy would have an expected annual t