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Prevalence, knowledge of long-term effects, and associated factors of alcohol consumption among adults in the Hohoe Municipality, Volta Region - Ghana.

BACKGROUND: Alcohol consumption is a significant and growing public health concern in Ghana, where it contributes to rising rates of non-communicable diseases, social dysfunction, and economic burden. Despite its impact, municipality-level data on alcohol use among the general adult population remains scarce, creating an evidence gap that limits the development of targeted, context-specific interventions. Prior studies in Hohoe Municipality have been restricted to youth and tertiary student populations, leaving the broader adult population unexamined. AIM: This study aimed to determine the pr

The Association Between Family History of Upper Gastrointestinal Cancer and the Risk of Death from Upper Gastrointestinal Cancer-based on Linxian Dysplasia Nutrition Intervention Trial (NIT) Cohort.

OBJECTIVE: Explore the influence of family history of upper gastrointestinal (UGI) cancer on UGI cancer death, based on the Linxian Dysplasia Nutrition Intervention Trial (NIT) cohort. METHODS: Family history of UGI cancer was defined as at least one first-degree relative (parent, child, or sibling) had a history of esophageal or gastric cancer. Cancer death was carried out by ICD-10 code. Family history information was collected at baseline and cancer deaths were assessed at each annual follow-up. The COX proportional risk model was used to estimate the hazard ratio (HR) and 95% confidence i

Antidepressant-like effect of Kyllinga brevifolia rhizomes in male mice and chemical characterization of the components of the active ethyl acetate fraction.

ETHNO-PHARMACOLOGICAL RELEVANCE: Kyllinga brevifolia rhizomes (Cyperaceae) are used in Paraguayan traditional medicine as a refreshing beverage, and is claimed to own digestive, diuretic, sedative, tonic, antispasmodic and sudorific properties. We have previously reported that its hydro- ethanolic rhizome extract possess sedative, anxiolytic and anti-aggressive-like effects in mice. However, information on its potential for treatment of syndromes associated with mood disorders is scarce. AIM OF THE STUDY: The purpose of this study is to characterize the putative antidepressant-like effects of

Breaking the obesity-cancer link: assessing European school-based and complementary obesity-prevention strategies and their implementation obstacles

Nowadays, obesity among children and adolescents is considered an additional factor in cancer development during adulthood. These facts are supported by current epidemiological studies. To address these challenges, a wide range of obesity prevention programmes have been launched in Europe, promoting actions for personalized healthy dietary behaviors, physical exercise, and combinations of both, often using e-health platforms. Another pillar of interventions is school-based policies, such as limiting access to high-fat and high-sugar foods or providing healthy food vouchers, which represent ano

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… Portugal's case Portugal implemented a tiered sugar-sweetened beverage (SSB) tax in 2017, one of Europe's earlier fiscal interventions targeting obesity prevention, complemented by school health-promotion programmes and incentives for product reformulation ( 61 ). … The future of the sweetened beverages tax in Portugal . Lancet Public Health . ( 2018 ) 3 : e562 . doi: 10.1016/S2468-2667(18)30240-8 30522681 62. Goiana-da Silva F Severo M Cruz e Silva D Gregório MJ Allen LN Muc M . …

Therapeutic Potential of Chlorogenic Acid in Chemoresistance and Chemoprotection in Cancer Treatment.

Chemotherapeutic drugs are indispensable in cancer treatment, but their effectiveness is often lessened because of non-selective toxicity to healthy tissues, which triggers inflammatory pathways that are harmful to vital organs. In addition, tumors' resistance to drugs causes failures in treatment. Chlorogenic acid (5-caffeoylquinic acid, CGA), found in plants and vegetables, is promising in anticancer mechanisms. In vitro and animal studies have indicated that CGA can overcome resistance to conventional chemotherapeutics and alleviate chemotherapy-induced toxicity by scavenging free radicals

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… These findings suggest that the extraction of CGA is influenced by factors such as duration and maceration during the coffee beverage preparation process [ 38 ]. … For instance, they could be utilized in the development of biofortified beverages aimed at combating obesity, providing antioxidant protection, and reducing inflammation [ 48 ]. …

Использование каннабиса и риск возникновения периодонтита и негативных последствий для здоровья полости рта: систематический анализ литературы.

Каннабис широко употребляется во всем мире. К числу общих методов потребления относятся курение, оплодотворение и потребление съедобных веществ. Несмотря на все более широкое использование каннабиса, его воздействие на лечение и лечение расстройств, связанных с оральным здоровьем, по-прежнему недостаточно изучено. Каннабис ассоциируется с негативными оральными последствиями, такими, как периодонтит, ксеростомия, кариес и ингивит. Эти отрицательные оральные эффекты осложняют стоматологическую помощь. Был проведен систематический обзор литературы с целью поиска баз данных PubMed, EMBASE и Cochra

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… Le A et al. reported that 46.7% of cannabis users frequently consumed sugary beverages or snacks compared to 26.3% of non-users (adjusted prevalence ratio 1.26; 95% CI 1.07-1.48) [ 20 ]. … The increased risk of dental caries with cannabis use can be further attributed indirectly to behavioral factors, such as sugary beverage consumption and poor oral health [ 20 , 34 , 35 ]. …

The role of dairy food intake for improving health among black Americans across the life continuum: A summary of the evidence.

Decades of health data show major health disparities occurring at every life stage between Black and White Americans. These disparities incl … cium, and magnesium; and simultaneously consume excessive amounts of fast foods and sugar-sweetened beverages to a greater degree than other racial/ethnic groups. Therefore, strategies that can help improve dietary patterns for Black Americans could make up a major public health opportunity for reducing nutrition-related diseases and health disparities acro …

School food policy in secondary schools in England and its impact on adolescents' diets and dental health: the FUEL multiple-methods study.

BACKGROUND: School food standards are a legal requirement for state-funded schools in England and are designed to promote healthy eating in … all time points, and higher consumption of confectionery during the school day and sugar-sweetened beverages over 24 hours. There were no differences in dental outcomes between the two groups. Twenty-one staff/governors and 137 pupils participated in the qualitative study. Staff described balancing school food standards compliance with conflicting prioriti …

NTP monograph on the state of the science concerning fluoride exposure and neurodevelopment and cognition: a systematic review.

BACKGROUND: Fluoride is a common exposure in our environment that comes from a variety of sources and is widely promoted for its dental and overall oral health benefits. Contributions to an individual's total exposure come primarily from fluoride in drinking water, food, beverages and dental products. A 2006 evaluation by the National Research Council (NRC) found support for an association between consumption of high levels of naturally occurring fluoride in drinking water and adverse neurological effects in humans and recommended further investigation. The evidence reviewed at that time was f…

Point-of-use fortification of foods with micronutrient powders containing iron in children of preschool and school-age.

BACKGROUND: Approximately 600 million children of preschool and school age are anaemic worldwide. It is estimated that at least half of the cases are due to iron deficiency. Point-of-use fortification of foods with micronutrient powders (MNP) has been proposed as a feasible intervention to prevent and treat anaemia. It refers to the addition of iron alone or in combination with other vitamins and minerals in powder form, to energy-containing foods (excluding beverages) at home or in any other place where meals are to be consumed. MNPs can be added to foods either during or after cooking or imm…

NTP technical report on the toxicology and carcinogenesis studies of beta-myrcene (CAS No. 123-35-3) in F344/N rats and B6C3F1 mice (Gavage studies).

UNLABELLED: Beta-myrcene, an acyclic unsubstituted monoterpene, and the essential oils which contain it are used as intermediates in the production of terpene alcohols (geraniol, nerol, and linalool), which, in turn, serve as intermediates in the production of aroma and flavor chemicals. Thus beta-myrcene is used widely in cosmetics, soaps, and detergents and as a flavoring additive in food and beverages. Beta-myrcene is also the major constituent of hop and bay oils, which are used in the manufacture of alcoholic beverages. Beta-myrcene was nominated for study by the National Institute of Env…

NTP technical report on toxicity studies of urethane in drinking water and urethane in 5% ethanol administered to F344/N rats and B6C3F1 mice.

Urethane, a byproduct of fermentation found in alcoholic beverages, is carcinogenic in rodents and is classified by the International Agency for Research on Cancer as a possible human carcinogen. The United States Food and Drug Administration nominated urethane for study because of the widespread exposure of humans through the consumption of fermented foods and beverages and because of a lack of adequate dose-response data about the carcinogenicity of urethane with and without the coadministration of ethanol. Comparative studies of urethane in drinking water and in 5% ethanol were conducted to…

A case of recto-sigmoid endometriosis mimicking carcinoma.

OBJECTIVE: To evaluate the technical success, safety and outcome of endovascular coiling procedure in intracranial aneurysms. METHODS: From April 2003 to April 2009, 43 patients (23 males and 20 females), age range 11 to 70 years, mean age 46.67 +/- 11.57 years were treated for intracranial aneurysms by detachable coil deployment at Radiology Department of Aga Khan University Hospital. Aneurysm rupture with subarachnoid haemorrhage was the cause of presentation in 39 patients while 4 patients were diagnosed with un-ruptured aneurysms. At time of presentation, grading of subarachnoid haemorrha

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… Introduction Fermented beverages undergo diverse biochemical changes driven by microbial activity. … These findings indicate that CFLI can serve as a suitable plant-derived matrix for controlled mixed-culture fermentation and highlight its potential relevance to fermented beverage development. …

Overview of nutritional approach in hematopoietic stem cell transplantation: COVID-19 update.

The coronavirus disease 2019 (COVID-19) is caused by the newly discovered SARS-CoV-2. Hematopoietic stem cell transplantation (HSCT) is a high-risk procedure. The novelty of COVID-19 has created more uncertainty during all phases of HSCT. It is thought that HSCT patients taking immunosuppressive agents are more likely to contract COVID-19 than healthy individuals are. Appropriate care precautions should be taken with patients undergoing HSCT to minimize the risk of COVID-19, and appropriate treatment methods must be followed in patients infected with COVID-19. Malnutrition has become a signifi

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… As beverages create a feeling of satiety, very few drinks should be consumed with meals. Regular exercise can also lead to an increased appetite. Exercise can be done in consultation with a physician[ 63 ]. … The second phase is the reintroduction of iso-osmotic, low-residue as well as lactose-free beverages to compensate for the loss of intestinal enzymes secondary to changes in the intestinal villi and mucosa. …

Anticancer Potential of Whey Proteins-A Systematic Review of Bioactivity and Functional Mechanisms.

Cancer remains a primary global health concern, with treatment-related side effects and malnutrition posing significant challenges to patient care and recovery. In recent years, there has been growing interest in the therapeutic potential of functional food components, especially whey proteins (WPs), due to their notable antioxidant, immunomodulatory, and anticancer properties. This systematic review explores the effects of WPs across various cancer types and assesses their value as supportive nutritional agents. A thorough literature search was conducted in PubMed, Scopus, and Web of Science

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… Similar protective mechanisms have been observed in prostate cancer, where Rosa et al. (2020) reported that a fermented WP-based beverage exerted antiproliferative and pro-apoptotic effects on prostate cancer cells through caspase activation and mitochondrial disruption [ 27 ]. … Antiproliferative and apoptotic effects of probiotic whey dairy beverages in human prostate cell lines. Food Res. Int. 2020;137:109450. doi: 10.1016/j.foodres.2020.109450. 28. Badr G., Sayed E.A., Abdel-Ghaffar W.H., Badr B.M., Sayed L.H., Sayed A., Mahmoud M.H., Alamery S. …

The Effects of Artificial Sweeteners on Intestinal Nutrient-Sensing Receptors: Dr. Jekyll or Mr. Hyde?

The consumption of artificial and low-calorie sweeteners (ASs, LCSs) is an important component of the Western diet. ASs play a role in the pathogenesis of metabolic syndrome, dysbiosis, inflammatory bowel diseases (IBDs), and various inflammatory conditions. Intestinal nutrient-sensing receptors act as a crosstalk between dietary components, the gut microbiota, and the regulation of immune, endocrinological, and neurological responses. This narrative review aimed to summarize the possible effects of ASs and LCSs on intestinal nutrient-sensing receptors and their related functions. Based on the

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… In contrast, in another cohort study, the prevalence of multiple myeloma was not associated with aspartame and sugar-sweetened beverage consumption [ 97 ]. 4.5. … There was a significant positive correlation between aspartame-sweetened beverages and coronary heart disease risk [ 106 ]. …

Geneva cocktail for cytochrome p450 and P-glycoprotein activity assessment using dried blood spots.

The suitability of the capillary dried blood spot (DBS) sampling method was assessed for simultaneous phenotyping of cytochrome P450 (CYP) enzymes and P-glycoprotein (P-gp) using a cocktail approach. Ten volunteers received an oral cocktail capsule containing low doses of the probes bupropion (CYP2B6), flurbiprofen (CYP2C9), omeprazole (CYP2C19), dextromethorphan (CYP2D6), midazolam (CYP3A), and fexofenadine (P-gp) with coffee/Coke (CYP1A2) on four occasions. They received the cocktail alone (session 1), and with the CYP inhibitors fluvoxamine and voriconazole (session 2) and quinidine (sessio

The 11th NORDIC NUTRITION CONFERENCE NNC2016.

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Take the reins: a study protocol of a randomized controlled trial testing the effects of time-restricted eating vs. nutrition control on cancer-related fatigue among survivors of hematological malignancies.

BACKGROUND: Cancer-related fatigue is one of the most common and debilitating side effects of cancer and its treatments. Fatigue may stem from disruptions in circadian rhythms and dysregulation of glucose metabolism, which can be improved through time-restricted eating. Time-restricted eating is a daily eating pattern that entails consuming food within a defined, consistent window (e.g., 10 h) every day. When the eating window aligns with the daylight hours, it can entrain circadian processes and modulate physiological regulation of whole-body metabolism. It is hypothesized that time-restricte

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… Calorie-free foods and beverages such as chewing gum, diet soda, and herbal tea, are discouraged outside the eating window. … Participants will be asked to self-report the time of their typical first food/beverage intake and their typical last food/beverage intake at night over the previous week. The eating window will be calculated, and its length will be compared between arms using a t-test. …

The Mediterranean Diet, a Rich Source of Angiopreventive Compounds in Cancer.

Diet-based chemoprevention of cancer has emerged as an interesting approach to evade the disease or even target its early phases, reducing its incidence or slowing down tumor progression. In its basis in the essential role of angiogenesis for tumor growth and metastasis, angioprevention proposes the use of inhibitors of angiogenesis in cancer prevention. The anti-angiogenic potential exhibited by many natural compounds contained in many Mediterranean diet constituents makes this dietary pattern especially interesting as a source of chemopreventive agents, defined within the angioprevention str

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… Beverages Attending to beverages included in the MD, apart from the daily consumption of water and the low intake of red wine within principal meals, the moderate consumption of coffee and herbal tea represents an important part of the MD [ 150 ]. … Focusing in the potential role of coffee as an angiopreventive beverage, some of these compounds have shown its ability to inhibit angiogenesis [ 161 , 162 ]. This is the case of kahweol ( Figure 3 ), an antioxidant diterpene present in coffee beans and unfiltered coffee beverages. …