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Factors Associated With Community Health Worker Performance Differ by Task in a Multi-Tasked Setting in Rural Zimbabwe.

BACKGROUND: Zimbabwe, like most low-income countries, faces health worker shortages. Community health workers (CHWs) bridge this gap by delivering essential health services and nutrition interventions to communities. However, as workloads increase, CHWs' ability to provide quality services may be compromised. We studied influences upon CHWs' performance related to pregnancy surveillance and nutrition and hygiene education in rural Zimbabwe. METHODS: In the context of a cluster-randomized trial conducted in 2 rural districts between November 2012 and March 2015, 342 government-employed CHWs id

[Prevention of Complications Following Surgical Procedures of the Upper Gastrointestinal Tract].

Surgical procedures of the upper gastrointestinal tract remain associated with substantial perioperative morbidity, particularly after oesophagectomy and gastrectomy. This review outlines current evidence that prevention of complications should be understood as a phase-spanning concept integrating preoperative optimisation, intraoperative quality assurance, and postoperative standardisation. Prehabilitation, nutritional optimisation, and risk-adapted patient preparation may reduce overall and pulmonary complications and may also lower the risk of anastomotic leakage in selected settings. Intra

Microplastics in Foods Intended for Health Purposes: From Dietary Supplements to Clinical Nutrition Products.

Microplastics (MPs) are pervasive contaminants that have been detected throughout the food chain. Their presence raises concerns in foods intended for health-related purposes, as these products are often consumed by vulnerable populations such as infants, older adults, and patients requiring clinical nutrition support. These groups may be more susceptible to contaminant exposure and may rely heavily on specialized foods. Therefore, understanding the occurrence and potential risks of MPs in such products is important. This review summarizes the current state of knowledge regarding the presence,

Exploring Facilitators and Barriers of Cooking and Food Preparation Among Urban-Suburban and Rural-Remote Residents: A Mixed-Methods Concept Mapping Study.

OBJECTIVE: To examine factors influencing cooking and food preparation behaviors to broaden the measurement and understanding of food agency in urban-suburban and rural-remote settings. METHODS: Thirty-nine adults from Northern and Southwest Virginia completed concept mapping tasks (brainstorming, sorting, and rating) and group interpretation sessions. Cohorts were analyzed separately to retain contextual specificity. Baseline food agency scores were compared across demographics variables with nonparametric analysis. Concept maps were configured with multivariate analysis. RESULTS: Four shar

Immunonutritional biomarkers in osteoarthritis: mechanistic insights and prognostic potential.

Osteoarthritis (OA) is the most prevalent degenerative joint disease worldwide. Beyond structural injury to cartilage, synovium, and subchondral bone, OA is increasingly recognized as an immunometabolic disorder characterized by low-grade inflammation and dysregulated innate and adaptive immune responses. Nutritional biomarkers-derived from macro- and micronutrient status and metabolite signatures-can shape the OA inflammatory microenvironment by modulating macrophage polarization, T-cell subset balance, cytokine networks, and key signaling programs (e.g., NF-kappaB, JAK/STAT, NLRP3 inflammaso

Schisandrin A, a dietary lignan from Schisandra chinensis, ameliorates cognitive deficits in AlCl₃/D-galactose-treated mice.

Alzheimer's disease (AD) is a progressive neurodegenerative disorder with limited disease-modifying therapies. Chronic aluminum exposure, a well-recognized environmental risk factor, exacerbates AD pathogenesis by driving oxidative stress and neuroinflammation. Schisandrin A (SchA), a bioactive lignan from the medicinal and edible plant Schisandra chinensis, exhibits promising antioxidant and anti-inflammatory properties, yet its nutritional relevance for AD intervention remains undefined. This study evaluated SchA's neuroprotective potential in an AlCl₃/D-galactose-induced cognitive impairmen

Brazilian Psychiatric Association Guidelines for the Treatment of Eating Disorders.

Eating disorders (ED), such as anorexia nervosa (AN), bulimia nervosa (BN), and binge eating disorder (BED), are serious psychiatric conditions that significantly impact psychological and medical health. This paper aims to summarize the recommendations of the Brazilian Association of Psychiatry - [Associação Brasileira de Psiquiatria (ABP)] for the treatment of EDs, based on the latest available evidence. Systematic reviews focused on the multidisciplinary treatment of ED were conducted. Findings were evaluated based on evidence strength, and recommendations using the evidence-based methodolog

The Role of Various Types of Diets in the Treatments of Depressive Disorders.

Depression is a prevalent and disabling psychiatric disorder, characterized by persistent disturbances in mood, cognition, and physiological processes, which collectively lead to substantial impairments in daily functioning and quality of life. This review provides a comprehensive overview of the biological mechanisms implicated in the pathophysiology of depression, including neurotransmitter dysregulation, oxidative stress, inflammatory processes, hypothalamic-pituitary-adrenal (HPA) axis dysfunction, mitochondrial impairment, and alterations in the gut-brain axis. Furthermore, it explores th

The Clinical Efficacy of Direct Swallowing Training for Patients with Dysphagia: A Systematic Review.

AIM: This review systematically evaluated the clinical effectiveness of direct swallowing training in patients with dysphagia. BACKGROUND: Dysphagia has a high prevalence rate and can seriously impair patients' quality of life. Although direct swallowing training within current rehabilitation frameworks demonstrates efficacy, there remains a lack of standardised protocols and an absence of comprehensive systematic reviews that incorporate multidimensional outcome measures. METHODS: Literature searches were conducted across CNKI, Wanfang Database, CBMdisc, PubMed, Web of Science, Embase, Coch

Exploring practitioners' perceptions of health behavior changes associated with psychedelic experiences.

In addition to evidence supporting the use of psychedelics in treating alcohol and tobacco misuse, emerging research suggests that psychedelic experiences may also facilitate beneficial changes in other health behaviors, such as diet, exercise, and meditation. This retrospective, survey-based study explored perceived health behavior changes following psychedelic experiences, from the perspective of 96 psychedelic practitioners, working in both legal and underground contexts. Practitioners reported on perceived changes in their clients' or patients' behaviors, including physical activity, diet

The Role of Plant-Based Diets and Personalized Nutrition in Endometriosis Management: A Review.

Endometriosis is a chronic, estrogen-dependent inflammatory condition that affects multiple organ systems and significantly impairs the quality of life in women of reproductive age. While conventional hormonal therapies may alleviate symptoms of endometriosis, they are also frequently associated with intolerable side effects. As a result, there is growing interest in complementary, non-invasive strategies to support long-term disease management. This review explores the potential of plant-based diets and personalized nutrition as adjunctive approaches in endometriosis care. Plant-based dietary

Diet-driven microbiome changes and physical activity in cancer patients.

Exploring the role of the gut microbiome in oncology is gaining more attention, mainly due to its ability to shape the immune system in cancer patients. A well-balanced microbial composition forms a symbiotic relationship with the host organism. Mounting evidence supports the potential of modifiable lifestyle factors, such as diet and physical activity, in restoring intestinal dysbiosis related to cancer development and treatment. In this Minireview, we describe the host-microbiome interplay following different dietary patterns, including a high-fat diet, fiber-rich diet, diet rich in rice and

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… Malnutrition and nutritional support Investigating the role of the diet-microbiome relationship in malnutrition is in line with the findings that nutritional deficiencies significantly correlate with the response to anti-cancer therapy ( 79 , 80 ). … Nutritional support and prophylactic swallowing exercises, performed before dysphagia or problematic swallowing development, improved patient outcomes ( 84 ). …

How Can Nutrition Research Better Reflect the Relationship Between Wasting and Stunting in Children? Learnings from the Wasting and Stunting Project.

Childhood wasting and stunting affect large numbers of children globally. Both are important risk factors for illness and death yet, despite the fact that these conditions can share common risk factors and are often seen in the same child, they are commonly portrayed as relatively distinct manifestations of undernutrition. In 2014, the Wasting and Stunting project was launched by the Emergency Nutrition Network. Its aim was to better understand the complex relationship and associations between wasting and stunting and examine whether current separations that were apparent in approaches to poli

[Infected pancreatic necrosis: Treatment with antibiotics alone. Would this be the first step of the step-up approach?].

INTRODUCTION: In 1994, Claudio Bassi reported a case of medical treatment for infected pancreatic necrosis (IPN); then since 1996 numerous articles of case series were published with treatment only with antibiotics with good outcomes. OBJECTIVES: To present our experience in the management of patients with IPN with antibiotics (without drainage). METHODS: We retrospectively reviewed cases with a diagnosis of IPN from January 2018 to October 2020, focusing on those cases that were treated conservatively (hydro-electrolyte, nutritional support and antibiotics). The diagnosis was made by observ…

Phase angle (PhA) in overweight and obesity: evidence of applicability from diagnosis to weight changes in obesity treatment.

Phase angle (PhA) is a recently proposed marker of nutritional status in many clinical conditions. Its use in patients with obesity presents different critical concerns due to the higher variability of the two measured parameters (resistance, R, and reactance, Xc) that contribute to the determination of PhA. Controversial is the relation between PhA and BMI that might vary with graded levels of obesity due to the variation in fat and free fat mass. Obesity is frequently associated with metabolic, hepatic, cardiovascular and kidney diseases that introduce variations in PhA values, in relation t

Combination of antibiotics, gastric lavage and nasojejunal feeding-an effective alternative for the management of acute phlegmonous gastritis: a case report.

BACKGROUND: Phlegmonous gastritis is a rare bacterial infection of the gastric wall, characterised by purulent inflammation of the gastric m … cs according to the antibiogram, and importantly, with continuous gastric lavage and individualised nutritional support therapy. He eventually recovered well and was discharged with no abdominal symptoms. CONCLUSIONS: Our case indicates that early diagnosis and immediate treatment are crucial to achieve positive outcomes. The combination of sensitive antibiotics, ga …

Parental Reports on Early Autism Behaviors in Their Children with Fragile X Syndrome as a Function of Infant Feeding.

This study evaluates the prevalence of autistic behaviors in fragile X syndrome as a function of infant diet. Retrospective survey data from the Fragile X Syndrome Nutrition Study, which included data on infant feeding and caregiver-reported developmental milestones for 190 children with fragile X syndrome enrolled in the Fragile X Online Registry with Accessible Database (FORWARD), were analyzed. Exploratory, sex-specific associations were found linking the use of soy-based infant formula with worse autistic behaviors related to language in females and self-injurious behavior in males. These

Use of Continuous Glucose Monitoring to Assess Parenteral Nutrition-Induced Hyperglycemia in an Adult Patient With Severe COVID-19.

Many patients admitted to the intensive care unit (ICU) are acutely malnourished and often require aggressive and early nutrition support with parenteral nutrition (PN). However, PN-induced hyperglycemia is a predictor of hospital mortality and is associated with increased length of stay. Elevated blood glucose in hospitalized patients with coronavirus disease 2019 (COVID-19) is also associated with increased mortality. Real-time continuous glucose monitoring (rtCGM) is primarily used in the outpatient setting, but there is rapidly growing interest in its applicability to help treat dysglycemi

Nutrition Management in Older Adults with Diabetes: A Review on the Importance of Shifting Prevention Strategies from Metabolic Syndrome to Frailty.

The increasing prevalence of older adults with diabetes has become a major social burden. Diabetes, frailty, and cognitive dysfunction are closely related to the mechanisms of aging. Insulin resistance, arteriosclerosis, chronic inflammation, oxidative stress, and mitochondrial dysfunction may be common mechanisms shared by frailty and cognitive impairment. Hyperglycemia, hypoglycemia, obesity, vascular factors, physical inactivity, and malnutrition are important risk factors for cognitive impairment and frailty in older adults with diabetes. The impact of nutrients on health outcomes varies w

[Anthropometric indicators of physical development and nutritional status employed in hygiene practice in Russia].

In the current review, we consider the main working methods of Russian hygienists to assess anthropometric indices using a) regional data on (populational) variability of the concerning measurements and b) unified reference data applicable in most regions. An analysis showed that in most cases, the regional standards are based on average values and variabilities derived from a local sample, which can not serve as a working normative. As a result, these so called "standards" do not provide information on how healthy children should develop, and the assessments inferred are difficult to integrat