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Interventions for preventing falls in older people in care facilities.

RATIONALE: Falls in care facilities are common events, causing considerable morbidity and mortality for older people. This is an update of a review on interventions in care facilities and hospitals first published in 2010 and updated in 2012 and 2018 on interventions in care facilities and hospitals. This review has now been split into separate reviews for each setting. OBJECTIVES: To assess the benefits and harms of interventions designed to reduce the incidence of falls in older people in care facilities. SEARCH METHODS: We searched the Cochrane Central Register of Controlled Trials (CENTR

Preliminary Planning for Mars Sample Return (MSR) Curation Activities in a Sample Receiving Facility (SRF).

The Mars Sample Return Planning Group 2 (MSPG2) was tasked with identifying the steps that encompass all the curation activities that would happen within the MSR Sample Receiving Facility (SRF) and any anticipated curation-related requirements. An area of specific interest is the necessary analytical instrumentation. The SRF would be a Biosafety Level-4 facility where the returned MSR flight hardware would be opened, the sample tubes accessed, and the martian sample material extracted from the tubes. Characterization of the essential attributes of each sample would be required to provide enoug

[SENTIERI - Epidemiological Study of Residents in National Priority Contaminated Sites. Sixth Report].

INTRODUCTION ADN OBJECTIVES: The Sixth Report presents the results of the "SENTIERI Project: implementation of the permanent epidemiological surveillance system of populations residing in Italian Sites of Remediation Interest", promoted and financed by the Italian Ministry of Health (Centre for Disease Control and Prevention - CCM Project 2018). The aim of this study is to update the mortality and hospitalization analyses concerning the 6,227,531 inhabitants (10.4% of the Italian population) residing in 46 contaminated sites (39 of national interest and 7 of regional interest). The sites inclu

A mixed methods evaluation of patient perspectives on the implementation of an electronic health record-integrated patient-reported symptom and needs monitoring program in cancer care.

BACKGROUND: As cancer centers have increased focus on patient-centered, evidenced-based care, implementing efficient programs that facilitate effective patient-clinician communication remains critical. We implemented an electronic health record-integrated patient-reported symptom and needs monitoring program ('cPRO' for cancer patient-reported outcomes). To aid evaluation of cPRO implementation, we asked patients receiving care in one of three geographical regions of an academic healthcare system about their experiences. METHODS: Using a sequential mixed-methods approach, we collected feedbac

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… Use of implementation science (IS) methods to bridge the research-to-practice translation gap has been shown to augment success [ 17 , 18 ]. … Implementation science: what is it and why should I care? Psychiatry Res. 2020;283:112376. doi: 10.1016/j.psychres.2019.04.025. 21. Smith JD, Norton WE, Mitchell SA, Cronin C, Hassett MJ, Ridgeway JL, et al. …

Использование имплементационных стратегий для поощрения применения психологических методов у лиц с множественным склерозом: протокол аналитического обзора.

ЦЕЛЬ: Настоящий документ направлен на стандартизацию процедуры аналитического обзора для завершения аналитического обзора. Предлагаемый обзор аналитического исследования преследует следующие цели: 1) определить объем литературы, на основе которой стратегии осуществления использовались для разработки, осуществления и поддержания психологического вмешательства для лиц с множественным склерозом (PwMS) и 2) изучить вопрос о том, каким образом принципы равенства, разнообразия, инклюзивности и доступности учитываются в этих стратегиях осуществления и в более широком плане психологических мерах. ВВЕД

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… Furthermore, one persistent gap in the field of implementation science is the lack of equity, diversity, inclusion and accessibility (EDIA) considerations when developing and implementing new healthcare interventions [ 16 ]. … To mitigate this, the search strategy included broad terms related to implementation science based on previous literature in the field. …

20 Years of Legislation - How Australia Has Responded to the Challenge of Regulating Genetically Modified Organisms in the Clinic.

•In contrast to the prior voluntary system, since 2001, gene technology in Australia has been regulated under a legislated national Gene Technology Regulatory Scheme which is administered by the Gene Technology Regulator.•The Scheme provides science-based assessment of the potential risks of gene technology to the health and safety of people and the environment.•It complements the role of the Australian Therapeutic Goods Administration which regulates all therapeutic products in Australia to ensure they are safe and effective.•Recent reforms to the Scheme contribute to, and anticipate, the con

Symptom Management Guideline Implementation Among Nurses in Cancer-Specific Outpatient Settings: A Scoping Review of Barriers, Facilitators, and Implementation Strategies.

BackgroundOncology outpatients experience high levels of distressing cancer-related symptoms. Nurses can provide high-quality outpatient cancer symptom management following clinical practice guideline recommendations; however, these guidelines are inconsistently used in practice. Understanding contextual factors influencing implementation is necessary to develop tailored implementation strategies.ObjectivesTo identify and describe (1) barriers and facilitators influencing symptom management guideline adoption, implementation, and/or sustainability among nurses in cancer-specific outpatient set

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… As such, nursing graduate programs should ensure master’s degree–prepared nurses receive training in implementation science to prepare APNs to effectively lead this work. … Implications for Research This body of literature could be improved through enhanced reporting of implementation strategies following established recommendations from the field of implementation science 22 26 27 and greater use of implementation science frameworks, which has previously been noted in …

Using Genomic Data in Personalized Oncology Medicine: An Exploratory Expert-Elicitation Study with Narrative Regulatory Mapping of Regulations, Implementations, and Challenges in Saudi Arabia.

BACKGROUND/OBJECTIVES: Personalized medicine represents a transformative approach to healthcare in Saudi Arabia. However, a significant research gap exists regarding the specific regulatory, implementation, and practical challenges of integrating genomic data into personalized oncology care in the Saudi context. We aimed to conduct an exploratory assessment of the current regulatory landscape, practices, and challenges related to genomic data use in personalized oncology in Saudi Arabia and to identify regulatory and practical gaps, propose actionable solutions, and outline future directions f

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… Limitation Note: These recommendations are derived from expert opinions and a narrative regulatory review rather than from evidence synthesis from systematic reviews, cost-effectiveness analyses, or implementation science frameworks. …

Abstracts 12th PCNE working conference 'Partnering for better patient outcomes: challenges and opportunities 3-6 February 2021, University of Basel, Switzerland (was held online).

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Adaptation and Evaluation of a Symptom-Monitoring Digital Health Intervention for Patients With Relapsed and Refractory Multiple Myeloma: Pilot Mixed-Methods Implementation Study.

BACKGROUND: Relapsed and refractory multiple myeloma (RRMM) is a bone marrow cancer that requires systemic treatment, which often results in severe symptom burden. Recent studies have found that electronic patient-reported outcome (ePRO) interventions implemented in the clinic setting have had positive outcomes for other oncology populations. Evidence of the efficacy of a similar approach is lacking for patients with RRMM. OBJECTIVE: Recent recommendations for digital health interventions call for the publication of descriptions of iterative development processes in order to improve reproduci

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… This is the basis of implementation science, which is focused on “understanding and accelerating the integration of research findings and research-based innovations into everyday practice settings to improve health” [ 26 ]. … Leveraging Implementation Science to Improve Cancer Care Delivery and Patient Outcomes. J Oncol Pract. 2017 Aug;13(8):523–529. doi: 10.1200/jop.2017.024729. 27. Active Implementation Practice and Science. …

Internet-based device-assisted remote monitoring of cardiovascular implantable electronic devices: an evidence-based analysis.

OBJECTIVE: The objective of this Medical Advisory Secretariat (MAS) report was to conduct a systematic review of the available published evidence on the safety, effectiveness, and cost-effectiveness of Internet-based device-assisted remote monitoring systems (RMSs) for therapeutic cardiac implantable electronic devices (CIEDs) such as pacemakers (PMs), implantable cardioverter-defibrillators (ICDs), and cardiac resynchronization therapy (CRT) devices. The MAS evidence-based review was performed to support public financing decisions. CLINICAL NEED: CONDITION AND TARGET POPULATION: Sudden cardi

50th ESCP Symposium on Clinical Pharmacy, Polypharmacy and ageing - highly individualized, interprofessional, person-centered care : 19–21 October 2022, Prague, Czech Republic

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… Fostering implementation of health services research findings into practice: a consolidated framework for advancing implementation science. Implementation Science: IS. 2009; 4:50–50. …

Staff- and service-level factors associated with organisational readiness to implement a clinical pathway for the identification, assessment, and management of anxiety and depression in adults with cancer.

BackgroundOrganisational readiness is recognised as a key factor impacting the successful translation of research findings into practice. Within psycho-oncology, measuring organisational readiness and understanding factors impacting organisational readiness is crucial as it is often challenging to implement evidence-based findings into routine cancer care. In this quantitative study, we examined the level of organisational readiness of cancer services preparing to implement a clinical pathway for the screening, assessment, and management of anxiety and depression in adult cancer patients (the

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… A practical implementation science heuristic for organizational readiness: R = MC2. J Community Psychol. 2015;43(4):484–501. doi: 10.1002/jcop.21698. 6. Miake-Lye IM, Delevan DM, Ganz DA, Mittman BS, Finley EP. … An implementation science primer for psycho-oncology: translating robust evidence into practice. J Psychosoc Oncol Res and Pract. 2019;1(3):e14 . doi: 10.1097/OR9.0000000000000014. 12. Geerligs L, Shepherd HL, Butow P, Shaw J, Masya L, Cuddy J, et al. …

Создание барьеров и возможностей для осуществления программ самостоятельной терапии для пациентов с миломой: протокол качественного декриптационного исследования.

Множественная миелома (ММ) связана с наибольшим симптомным бременем всех гематологовых раковых заболеваний и, несмотря на значительное улучшение методов лечения с высокими показателями реагирования и выживаемости, все еще считается неизлечимой, причем пациенты в течение многих лет проходят многочисленные циклы лечения. Инъекции по подкожному методу (СК) являются распространенным способом доставки для текущей и будущей терапии ММ, при этом данные свидетельствуют о том, что программы, наделяющие пациентов или лиц, занимающихся уходом за больными, ответственностью за управление, могут принести по

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… Using Implementation Science to Capture Broad-Ranging Complexities Implementation science (IS) provides a systematic approach to understanding factors that influence the uptake of evidence-based interventions in practice [ 14 ]. … Bauer MS Kirchner J Implementation science: what is it and why should I care? Psychiatry Res 01 2020 283 112376 doi 10.1016/j.psychres.2019.04.025 Medline 31036287 15. …

Artificial Intelligence Resources for the Screening of Titles and Abstracts in Systematic Reviews: A Scoping Review.

IntroductionArtificial intelligence (AI) is a branch of technology enabling machines to emulate complex human skills; it can also entail problem-solving using bioinspired methods. It is used for automating systematic literature reviews (SLR), that is, defining a clinical question, locating relevant literature, preliminary screening, study evaluation, data extraction and analysis. Title and abstract screening is one of the most time-consuming and error-prone phases involved in developing a systematic review. While AI promises to expedite this process, adopting it faces challenges due to concern

Accelerating novel therapies for sickle cell disease with RWE: ASH RC Data Hub as a strategically coordinated registry network.

AbstractReal-world evidence (RWE) has been used to improve quality of care, accelerate innovation, and evaluate emerging therapies for drugs, devices, and biologics. The Coordinated Registry Network (CRN), aggregating and linking highly curated patient data, has emerged as a model for RWE generation that has guided the development of the American Society of Hematology Research Collaborative (ASH RC) Data Hub. With the aim of bolstering research, enhancing clinical care, and expediting evidence generation using RWE, the ASH RC and the Innovative Genomics Institute launched a joint initiative, "

Виртуальная реальность в области аутизма и физической терапии: метааналитический обзор клинических результатов и терапевтической эффективности.

Технология Virtual Reality (VR) стала трансформативной терапевтической инновацией в сфере здравоохранения, обеспечивая императивность three- многомерная, многочувствительная среда, способствующая практическому обучению, реабилитации и взаимодействию. Хотя результаты многочисленных исследований свидетельствуют о его преимуществах, эмпирические исследования в области основанных на VR методов лечения расстройства аутистического спектра (ASD) и физической терапии (PT) по-прежнему ограничиваются методологическими несоответствиями, небольшими размерами выборки и изменяющимися схемами вмешательства.

Impact of World Trade Center-Related Health Research: An Application of the NIEHS Translational Framework.

The World Trade Center Health Program (WTCHP) has a research mission to identify physical and mental health conditions that may be related to the 9/11 terrorist attacks as well as effective diagnostic procedures and treatments for WTC-related health conditions. The ability of the WTCHP to serve its members and realize positive impacts on all of its stakeholders depends on effective translation of research findings. As part of an ongoing assessment of the translational impact of World Trade Center (WTC)-related research, we applied the National Institute of Environmental Health Sciences (NIEHS)

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… Outcome modification studies examine characteristics or impacts of one or more health-related interventions and may include clinical research, health services research, implementation science, or public health or policy interventions. …

Proceedings of the 3rd IPLeiria's International Health Congress : Leiria, Portugal. 6-7 May 2016.

S1 Health literacy and health education in adolescence Catarina Cardoso Tomás S2 The effect of a walking program on the quality of life and well-being of people with schizophrenia Emanuel Oliveira, D. Sousa, M. Uba-Chupel, G. Furtado, C. Rocha, A. Teixeira, P. Ferreira S3 Diagnosis and innovative treatments - the way to a better medical practice Celeste Alves S4 Simulation-based learning and how it is a high contribution Stefan Gisin S5 Formative research about acceptability, utilization and promotion of a home fortification programme with micronutrient powders (MNP) in the Autonomous Region o

:: 8th Европейский конгресс фармацевтики: выдержки из выступлений

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