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Implementation of Physical Activity Programs for Rural Cancer Survivors: Challenges and Opportunities.

Physical activity after cancer diagnosis has been consistently associated with improvements in quality of life and prognosis. However, few cancer survivors meet physical activity recommendations, and adherence is even lower among those living in rural settings. The purpose of this quasi-experimental study was to evaluate the implementation of a clinic-based physical activity program for cancer survivors at a rural community oncology setting. We also examined changes in quality-of-life measures among 24 cancer survivors participating in the physical activity program and described challenges and

Experiences and perspectives of healthcare professionals, patients and caregivers toward the serious illness conversation guide: protocol for a qualitative meta-synthesis.

IntroductionExploring the experiences and perspectives of healthcare professionals, patients and caregivers toward serious illness conversations based on the Serious Illness Care Program is vital for improving communication with patients who are seriously ill, as has been shown in previous studies. However, few studies have carried out a systematic review to examine common themes, strengthen conclusions and identify gaps in the literature, the findings of which could help steer further research, policies and practice to improve more timely and person-centred conversations about the values and

SCS 6th Annual Meeting-EEVFA-11th International Congress of Biochemistry and Physiology of Exercise, Athens, Greece, 2023.

On behalf of the Strength and Conditioning Society (SCS) and the Hellenic Society of Biochemistry and Exercise Physiology (EEVFA), we are pleased to present the abstracts of the SCS 6th Annual Meeting and EEVFA-11th International Congress of Biochemistry and Physiology of Exercise. The event was held at the Hellenic Olympic Committee headquarters in Athens, Greece, on 19-22 October 2023, and comprised several invited sessions from international and national speakers on a variety of topics related to biochemistry and exercise physiology, strength and conditioning practices and their application

Exercise in allogeneic bone marrow transplantation: a qualitative representation of the patient perspective.

PurposeExercise is emerging as a vital aspect of care to alleviate the physical and psychosocial symptom burden associated with allogeneic bone marrow transplantation (BMT). Understanding the patient perspective regarding exercise is important to move towards implementation. This study aimed to characterise experiences and views regarding participation in an exercise program in adults receiving treatment for haematological disease with allogeneic BMT.MethodsIndividual semi-structured interviews were conducted with 35 participants from either an early- or late-commencing supervised group-based

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… A recent international “call to action” advised future research regarding exercise in oncology to focus on implementation science and health services research [ 29 ]. … Bauer MS Kirchner J Implementation science: what is it and why should I care? Psychiatry Res 2020 283 112376 10.1016/j.psychres.2019.04.025 31036287 14. …

A decision support tool with health economic modelling for better management of DVT patients.

BackgroundResponding to the increasing demand for Deep Vein Thrombosis (DVT) treatment in the United Kingdom (UK) at times of limited budgets and resources is a great challenge for decision-makers. Therefore, there is a need to find innovative policies, which improve operational efficiency and achieve the best value for money for patients. This study aims to develop a Decision Support Tool (DST) that assesses the impact of implementing new DVT patients' management and care policies aiming at improving efficiency, reducing costs, and enhancing value for money.MethodsWith the involvement of stak

Разработка Novel Digitals Eliction Measure for Clinical Use у пожилых людей с гематологическими злокачественными свойствами: Ценности-HM.

Введение. Недавнее расширение возможностей лечения пожилых людей, страдающих раком крови, повысило необходимость понимания предпочтений и ценностей пациентов для принятия решений о лечении. В настоящее время для клинического применения в этой группе населения не было подтверждено никаких мер по расчету значений. Величины-HM (показатель вымогательства для гематологовых злоумышленников) представляют собой новый показатель вымогательства, основанный на наилучших значениях масштаба. Он был разработан специально для пожилых людей, страдающих раком крови, с участием многих заинтересованных сторон, в

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… In this analysis, we found that patients found the online consent process inefficient and frequently did not return to complete subsequent measures due to the cumbersome electronic delivery platform of Values-HM. 55 We now have employed several implementation science strategies to reduce patient burden … Creating a tool for measuring preferences for treating blood cancers in older adults using implementation science . Blood . 2025 ; 146 ( suppl 1 ): 2644 . DOI: 10.1182/blood-2025-2644 56 Scheepers ERM Vondeling AM Thielen N van der Griend R Stauder R Hamaker ME . …

Виртуальная реалити-ческая подготовка по расстройствам похода в болезни Паркинсона: библиометрический и визуальный анализ горячих точек и тенденций с использованием CiteSpace и VOSviewer.

В настоящем исследовании на систематической основе рассматривается нынешнее положение дел, распределение горячих точек и тенденции развития виртуальных реалити-шоу (ВР) в целях совершенствования хитроумных расстройств в болезни Паркинсона. 2008 и 2025 был извлечен из баз данных " Web of Science " , " PubMed " и " CNKI " . В конечном счете, 535 Английский 18 Были включены китайские статьи. CiteSpace и VOSviewer использовались для визуального анализа тома публикаций, сетей сотрудничества (страны, авторы и учреждения), ключевых слов, группирования и вспыльчивых терми

Эффективность дыхательных упражнений с симптомами мочеиспускания, мышечной активностью и силой у женщин с множественным склерозом и недержанием мочевого мозга - протокол исследования для случайного контролируемого исследования.

Недержание мочевины (УИ) является распространенным и изнурительным заболеванием среди людей с множественным склерозом (МС) и более широко распространено среди женщин. За последнее десятилетие были проведены многочисленные исследования по изучению последствий обучения мышечных мышц тазовому полу (ПФМТ) в качестве средства лечения ИП у людей с НР. MS негативно влияет на легочную функцию даже на ранних стадиях заболевания, и у людей с MS может возникнуть дыхательная слабость мышц. Учитывая синергию между мышцами тазового пола (PFM) и респираторными мышцами, в ходе этого испытания будет проведена

Автоматическое отслеживание активного движения в многоразовом склерозе с использованием неконтролируемого машинного обучения

Справочная информация: Выявление активных повреждений в магнитно-резонансной съемке (MRI) имеет решающее значение для диагностики и планирования лечения множественных склерозов (MS). Активные повреждения МРТ выявляются после применения противопоказательных агентов на основе гадолиния (ГБЦА). Однако недавние исследования показали, что неоднократное применение ГБЦН приводит к накоплению ГД в тканях. Кроме того, администрация ГБКА увеличивает расходы на медицинское обслуживание. Таким образом, для повышения безопасности пациентов и снижения расходов на медицинское обслуживание важное значение име

Current landscape of innovative drug development and regulatory support in China.

The global pharmaceutical landscape remains dynamic and competitive, shaped by advancements in first-in-class therapies and breakthrough technologies. The United States has maintained its leadership in first-in-class therapies and breakthrough technologies, driven by advanced regulatory pathways, significant multinational corporation investments, a robust Research and Development (R&D) workforce, and continuous technological innovation. Additionally, global impact of the Food and Drug Administration (FDA) is further amplified through collaborations like Project Orbis, which facilitates simulta

Rare disease patients protection: theoretical discussion and institutional construction of orphan drug designation in China.

Orphan drugs play a vital role, often described as the "public goods of public goods." As a result, they demand robust policy support. Among these, the designation of orphan drugs serves as the pivotal and core element of the national incentive mechanism for such drugs. The designation of orphan drugs is a prerequisite and a key system to determine whether pharmaceutical enterprises are eligible to access policy support, which directly determines the effective output of orphan drugs and the fairness of public policies. However, there is still an urgent need to explore this system in China theo

Acceptability and appropriateness of a clinical pathway for managing anxiety and depression in cancer patients: a mixed methods study of staff perspectives.

BackgroundClinical pathways (CPs) can improve health outcomes, but to be sustainable, must be deemed acceptable and appropriate by staff. A CP for screening and management of anxiety and depression in cancer patients (the ADAPT CP) was implemented in 12 Australian oncology services for 12 months, within a cluster randomised controlled trial of core versus enhanced implementation strategies. This paper compares staff-perceived acceptability and appropriateness of the ADAPT CP across study arms.MethodsMulti-disciplinary lead teams at each service tailored, planned, championed and implemented the

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… Science and eHealth Group (RISe), The University of Sydney, Sydney, NSW, Australia. 19 Centre for Health Economics Research and Evaluation, University of Technology, Sydney, NSW, Australia. … Fostering implementation of health services research findings into practice: a consolidated framework for advancing implementation science. Implement Sci. 2009;4(1):1–5. doi: 10.1186/1748-5908-4-50. 24. Geerligs L, Rankin NM, Shepherd HL, Butow P. …

Haematological and Oncological Training Therapy With Stationary Strength and Cardio Machines (HOT) in Routine Cancer Care: A 3-Year Real-World Evaluation of Acceptance, Feasibility, Safety, and Effects.

BackgroundExercise improves physical function and health-related quality of life (HRQoL) in patients with cancer; however, nationwide structured programmes remain limited. A hospital in Germany implemented a donation-funded Haematological and Oncological Training Therapy with Stationary Strength and Cardio Machines (HOT), and a 3-year real-world data analysis aimed to evaluate its acceptance, feasibility, safety, and effects.MethodsHOT comprised 24 sessions of combined resistance and aerobic training, complemented by a sensorimotor module for patients with chemotherapy-induced peripheral neuro

Elements for assistance to patients with hematological malignancies to propose care lines: a scoping review.

Objectivesto identify the elements for assistance to patients with hematological malignancies to propose a care line.Methodsthis is a scoping review, anchored in the JBI theoretical framework, with searches carried out in April 2021, in eight electronic databases and 10 repositories of theses and dissertations.Resultsthe final sample consisted of 93 studies, and the main forms of assistance provided that can support a care line for this public were imaging tests, immunophenotyping, chemotherapy regimens, radiotherapy, infection management, assessment of nutritional status, maintenance of oral

Ассоциация гинекологов-преподавателей в области медицинского образования - обзор скопирования.

Экзамен по фону Pelvic является ядром, но в то же время вызывающим тревогу, клиническим навыком в высшем медицинском образовании. Традиционные подходы к преподаванию - зачастую оппортунистические или основанные на моделировании - подвергались критике за лишение технических навыков от реляционной и этической практики. В качестве альтернативной модели появились специально подготовленные педагоги, которые используют свои собственные тела для обучения и предоставления олицетворенной обратной связи. Цель этого аналитического обзора состояла в том, чтобы составить карту того, что известно о ПГС, чьи

Bridging the gap: a pre-post feasibility study of embedding exercise therapy into a co-located cancer unit.

PurposeTo establish the feasibility of embedding a flexible, exercise-based rehabilitation program into a cancer treatment unit to allow cancer survivors early exercise support.MethodA pre-post study was conducted using Bowen's Framework to describe key domains of feasibility: demand (referrals), acceptability (uptake, attendance, satisfaction), implementation (resources), practicality (adverse events, costs) and limited-efficacy (function, quality of life, self-efficacy). Participants were medically stable, adult cancer survivors receiving curative or palliative treatment for cancer at the he

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… A critical first step is to establish feasibility of embedding exercise therapy within pragmatic health service settings, using implementation science methodology [ 18 ]. Feasibility of exercise programs for cancer survivors has been established in controlled trial settings. … Czosnek L Implementing exercise in healthcare settings: the potential of implementation science Sports Med 2020 50 1 14 10.1007/s40279-019-01228-0 31749112 33. …

Precision Medicine Through Network Language: Integrating Clinical Insight and Data Expertise.

Precision medicine is facing a critical transition driven by the growing complexity of biological data and the insufficient ability of current models to translate such data into clinically meaningful information. Linear, single-gene approaches are no longer adequate to explain the multifactorial nature of most modern diseases, whose phenotypes emerge from combinations of genetic, molecular, and environmental factors. Network-based precision medicine addresses this by providing a systemic framework capable of integrating heterogeneous omics data, interactomes, and clinical information to identi

A roadmap for establishing institutional readiness for cellular therapies targeting solid tumours and autoimmune diseases.

Adoptive cellular therapies have revolutionised treatment of haematological malignancies and demonstrate potential in solid tumours and autoimmune disease. Real-world implementation remains limited by biological, logistical, and manufacturing barriers, restricting global uptake despite a rapidly expanding clinical trial portfolio. Effective implementation requires national and institutional readiness, multidisciplinary collaboration, scalable manufacturing, and robust infrastructure. Efforts should prioritise decentralised and "off the shelf" platforms, integrated referral networks, and AI-ass

Integrating Patient-Centred Research in the Canadian Cancer Trials Group.

The inclusion of patients as partners in research is a key link in the delivery of patient-centred care in healthcare systems. Despite genuine intentions to engage patients in authentic partnerships, efforts can result in tokenism and benefits of engagement are missed. Understanding how patient engagement provides value along the research to patient-care continuum and how to best engage patients as partners are key. This document describes the method taken by the Canadian Cancer Trials Group (CCTG) to implement meaningful patient centricity and engagement and the benefits realized. Originally,

Экспериментальное технико-экономическое обоснование исследования виртуальной оценки гейт на основе реальности с орехами у людей с множественным склерозом: исследовательский протокол.

Множественный склероз (МС) часто приводит к значительным нарушениям в походах и мобильности. Несмотря на то, что пешие брекеты обычно предписываются, их эффективность в реальном мире ограничивается недостаточной адаптацией. Традиционные клинические оценки основываются на субъективных масштабах и могут не в полной мере отражать проблемы повседневной жизни. Неизмеримая виртуальная реальность (VR) и износимые сенсоры предлагают перспективные решения для экологического мониторинга, однако их комбинированное использование по-прежнему не является приемлемым для ортопедической поддержки в MS. В рамка