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Efficacy of Silver Diamine Fluoride on Young Children With Severe Early Childhood Caries: A Randomized Clinical Trial.

IMPORTANCE: Dental caries is a highly prevalent yet preventable disease affecting more than 40% of US children, with severe early childhood caries (S-ECC) leading to serious health and economic consequences. This randomized clinical trial addresses critical evidence gaps by evaluating 38% silver diamine fluoride (SDF) effectiveness for caries arrest in young US children with S-ECC to inform US Food and Drug Administration (FDA) regulatory approval. OBJECTIVE: To assess the efficacy of 38% SDF vs placebo for arresting active cavitated dentin caries lesions in the primary dentition of US childr…

Assessment of Pulpal Oxygen Saturation in Healthy and Diseased Primary Teeth Using a Customized Pulse Oximeter Holder in Children Aged Four to Nine Years: A Cross-Sectional Study.

Introduction Accurate assessment of pulp vitality is essential for diagnosis and treatment planning in pediatric dentistry. Conventional pulp sensibility tests, including thermal and electric pulp testing, assess neural response rather than pulpal vascularity and often demonstrate limited reliability in primary teeth. Pulse oximetry provides a non-invasive, objective assessment of pulpal oxygen saturation; however, evidence regarding its use in primary dentition remains limited. This study evaluated pulpal oxygen saturation in healthy and diseased primary teeth using a customized pulse oximete…

Integrative morphological and DNA barcoding analysis of Forcipomyia (Lasiohelea) midges: cryptic diversity and first molecular detection of multiple Leishmania species in a leishmaniasis-endemic focus in Southern Thailand.

BACKGROUND: Ceratopogonid midges of the genus Forcipomyia (subgenus Lasiohelea) are small hematophagous insects widely distributed across tr … ired cutaneous leishmaniasis, during January and June 2025. Morphological examination of mandibular dentition, sensory pits, cibarial armature, and spermathecal structure was combined with mitochondrial cox1 barcoding, Bayesian and maximum likelihood phylogenetic analyses, and species delimitation methods (ASAP and mPTP). Because females of the subgenus Las …

[Impact of different registration methods on the accuracy of virtual occlusal records in implant restoration for multiple missing teeth: an in vitro study].

Objective: To investigate the impact of four registration methods on the accuracy of virtual occlusal records (VOR) in intraoral scanning for implant restorations with multiple missing teeth. Methods: A mandibular model simulating clinical conditions with multiple missing teeth (right first molar, left second premolar, left first molar, left second molar) and a maxillary compete dentition model were mounted on a semi-adjustable articulator. Subsequently, twelve 0.5 mm stainless steel spheres were adhered to reference positions (16, 46, 13, 43, 23, 33, 25, 35, 26, 36, 27, 37) as fiducial marker…

Insights Into Associations Between Oral and General Health Outcomes of Nursing Home Residents Based on InterRAI Data: Cross-Sectional Study.

BACKGROUND: Oral health of nursing home residents is generally poor, largely due to age-related conditions that increase their vulnerability … teeth (OR 1.7, 95% CI 1.1-2.5), and the need for dental referral (OR 1.8, 95% CI 1.4-2.3). Natural dentition and gender had a significant impact on oral health status. Low weight was associated with poor chewing function (OR 2.0, 95% CI 1.1-3.6) and dry mouth (OR 1.8, 95% CI 1.0-3.2), both associated with oral discomfort or pain (OR 6.8, 95% CI 3.3-14.0 an …

Predictors of the need for airway adjuncts during mask ventilation in Thai adult patients undergoing general anesthesia: A prospective observational study.

BACKGROUND: Mask ventilation is a cornerstone of airway management during general anesthesia, yet the need for airway adjuncts during mask ventilation remains poorly predicted by current preoperative assessments. We aimed to identify independent clinical predictors of this outcome in Thai adults undergoing elective surgery. METHODS: This single-center prospective observational study included 266 adults undergoing elective general anesthesia at a university hospital in Thailand between September 2018 and October 2019. Preoperative airway assessment included Mallampati classification, dentition…

Comparative assessment of oral hygiene awareness and periodontal knowledge among caregivers of children with and without intellectual disabilities: a cross-sectional comparative study.

OBJECTIVES: Individuals with intellectual disabilities (ID) experience disproportionately higher rates of periodontal disease. While biologi … assisted brushing techniques, early recognition of periodontal signs, and the importance of primary dentition. However, these results should be interpreted with caution given the cross-sectional design and differences in recruitment settings between the groups. CLINICAL SIGNIFICANCE: The widespread misconception that gingival bleeding is a benign consequen …

National Beef Quality Audit-2022: Transportation, mobility, and harvest-floor assessments of targeted characteristics that affect quality and value of cattle, carcasses, and by-products from fed steers and heifers.

The National Beef Quality Audit (NBQA)-2022 systematically evaluated quality characteristics of cattle, carcasses, and by products generated … the loin (30.0%), rib (23.7%), chuck (19.7%), and round (19.3%) were the most common locations. For dentition, 95.4% had 2 or fewer permanent incisors deemed as less than 30 mo of age. Offal/byproducts condemnations occurred for liver (28.5%), lung (20.9%), viscera (12.5%), head (4.5%), and tongue (1.8%). Compared numerically to NBQA (2016), although we obs …

Long-term effects of bone marrow transplantation on dental status in children with leukaemia.

Minimal data about oral and dental health in long-term survivors after BMT are available. We studied the dental status of 27 children (19 males, eight females) with leukaemia, followed up with a routine oral examination, panoramic tomogram and, when necessary, an endoral radiograph at a median of 2 years (range 1-10) after BMT. Community periodontal index treatment necessity (CPITN), dental caries, missing or filled permanent teeth (DMFT) and dento-facial alterations according to WHO criteria were registered and evaluated. Median age of the patients at BMT was 9 years (range 1.1-17.9). The mea

Consensus Statement on Full-Arch Implant Rehabilitations: Evidence-Based Recommendations from the Italian Consensus Conference.

Full-arch implant-supported rehabilitations are widely recognized as an effective treatment option for edentulous patients. Nevertheless, clinical decision-making regarding patient selection, surgical planning, prosthetic material choice, and long-term maintenance protocols remains heterogeneous and requires structured evidence-based guidance. A modified Delphi consensus process was conducted involving 29 experts during the Italian Consensus Conference. A systematic literature review covering the period 2015-2024 was performed, and the certainty of evidence was assessed using the Grading of Re

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… Operational Criteria for Periodontal Stability Assessment Prior to Full-Arch Rehabilitation The six-month periodontal stability criterion requires explicit operational thresholds, which the panel has formalised according to the pre-implant dentition status of the candidate. … For partially edentulous patients with residual dentition, IDRA should be used in combination with the Periodontal Risk Assessment (PRA) [ 13 ]. …

A randomized controlled trial of various MTA materials for partial pulpotomy in permanent teeth.

OBJECTIVES: The aim of this study was to evaluate and compare the clinical applicability of various MTA materials as partial pulpotomy materials in permanent teeth. METHODS: Partial pulpotomy was performed on 104 permanent teeth from 82 people (mean 29.3±14.8years old), who met the inclusion criteria in randomized clinical trial. The teeth were divided into three groups: ProRoot MTA (n=33), OrthoMTA (n=36), RetroMTA (n=35). Clinical examination and radiographic comparison were carried out at 1, 3, 6 and 12 months after the treatment. Survival analysis was performed using the Kaplan-Meier surv

Связанный с лекарствами остеонекроз челюсти у нескольких пациентов миэломы: серия случаев.

Остеонекроз челюсти (MRONJ), связанный с лекарственными препаратами, является осложнением антирепрессивной и антиангиогенной терапии, используемой при лечении злокачественных заболеваний, и может вызывать значительную функциональную и эстетичную заболеваемость у пациентов. Множественная миелома (ММ) — гематологическая порча плазмы и клеток, часто связанная с остеолитической болезнью костей. Антирезорптивная терапия (АРТ) уменьшает связанные со скелетом явления в MM и других магнатах с участием скелета, но связана с повышенным риском заболевания MRONJ. В настоящем документе представлены клиниче

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… Pre-existing oral health findings included anterior tooth surface loss, periodontal disease and a heavily restored dentition, with no history of denture use. … Baseline oral health assessment noted a heavily restored dentition with extracoronal restorations across the dentition and multiple implants, with no history of denture use. …

Two- to six-year outcomes of tunnel technique with connective tissue graft in multiple mandibular anterior recessions.

BACKGROUND: The purpose of this study is to report the 2-6 year outcomes of the tunnel technique with a connective tissue graft (TUN+CTG) in … optimizing both functional and esthetic outcomes in periodontal plastic surgery of the lower front dentition.

Evaluation of Smile Aesthetics in Dental Students: Perceptions of Tooth Colour Changes Due to Incisor Inclination and Micro- and Mini-Aesthetic Characteristics Assessed by Professionals and Laypersons.

Background: The present study investigated the relation between dental inclination, colorimetric variation, and aesthetic perception accordi … tions and overall smile attractiveness. A sample of 50 students with complete, lesion-free anterior dentition was analysed. To simulate the effect of orthodontic torque changes during colour analysis, subjects tilted their heads downward and upward, representing palatal and buccal crown torque, respectively. Standardized macro-intraoral photographs were cap …

Application of a 3D Fusion Model to Evaluate the Efficacy of Clear Aligner Therapy in Malocclusion Patients: Prospective Observational Study.

BACKGROUND: Investigating the safe range of orthodontic tooth movement is essential for maintaining oral and maxillofacial stability posttre … r therapy at our institution were screened; 136 patients (aged 13-35 years, fully erupted permanent dentition and periodontal pocket depth <3 mm) met the criteria. Baseline ("simulation") and posttreatment ("fusion") models were compared. Outcomes included upper core discrepancy (UCD), upper incisors anteroposterior discrepancy (UAP), lower Spee curve deep …

Discrepancies of maximal intercuspal position recorded by using four intraoral scanners at different dental chair positions: A clinical study.

STATEMENT OF PROBLEM: Discrepancies in the maximal intercuspal position (MIP) recorded using intraoral scanners (IOSs) have been reported. Additionally, changes in the mandible position have been reported when altering patient head posture, influencing the occlusal contacts between the maxillary and mandibular dentition. However, clinical studies analyzing MIP discrepancies recorded using different IOSs at different dental chair positions are scarce. PURPOSE: The purpose of this clinical study was to assess the trueness and precision discrepancies of the MIP captured using 4 IOSs at 3 differe…

Does orthodontic treatment using fixed appliances cause initial caries lesions?

DESIGN: Systematic review and meta-analysis of randomized clinical trials (RCTs), non-randomized studies of intervention (NRSIs), cohort and … The review question was defined in PICOS format as follows: Population (P), subjects with permanent dentition who having/had orthodontic therapy; Exposure (E), orthodontic therapy with fixed orthodontic appliance; Comparison/Control (C), no orthodontic treatment or intervention; Outcome (O), assessing incidence and/or prevalence of initial caries lesions (I …

Dentoskeletal comparison of miniscrew-anchored maxillary protraction with hybrid and conventional hyrax expanders: A randomized clinical trial.

INTRODUCTION: This randomized clinical trial aimed to compare the skeletal and dental effects of miniscrew-anchored maxillary protraction (M … HH group was composed of patients with Class III malocclusions in the late mixed or early permanent dentition treated with a HH expander with 2 miniscrews in the maxilla and 2 miniscrews in the anterior region of the mandible. Class III elastics were used from the maxillary first molars to the mandibular miniscrews placed between permanent canines and first …

[The extraction of the lower third molars: germectomy or late avulsion?].

INTRODUCTION: Lower third molars show the highest incidence of impaction and have been held responsible for pathologies such as pericoronitis, periodontitis, second molars tooth-crown resorption, pain, cysts or odontogenic tumors, primary or secondary crowding of the dentition. Early removal of these teeth to prevent the overmentioned problems is widely acknowledged, as many studies demonstrated a direct correlation between age and incidence of complications. These studies mostly refer to adult patients, while studies about germectomies are few. Because recent contributions showed that the ris…

The Early Iron Age elite grave from the Kapiteljska njiva barrow cemetery (Novo mesto, Slovenia): an approach to dental profiling through non-invasive and minimally-invasive techniques.

Kapiteljska njiva is a prehistoric cemetery located in the town of Novo mesto in southern Slovenia. There is a long history of archaeologica … ). The present study reveals that the dental remains from Kapiteljska njiva belong to the permanent dentition of a single individual and that only the right upper central incisor and third molar are completely absent. The remains of teeth exhibit a simple external morphology, characterised by the absence of morphological dental traits, with a notable except …