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Depression and anxiety disorders in patients with atrial fibrillation undergoing a pulmonary vein isolation: A systematic literature review and meta-analysis.

Atrial fibrillation (AF) is globally the most prevalent arrhythmia for which pulmonary vein isolation (PVI) is an effective intervention. A … were calculated using logistic regressions. Eighteen studies with a total of 9,691 observations for depressive disorders and 8,855 observations for anxiety disorders were included. The meta-analyses revealed an overall point prevalence of 20.10% [95% Confidence interval (CI): 13.31% to 29.18%] for depressive disorders and 25.18% [95% CI: 11.71% to 46.08%] for anxiety …

Virtual Reality-Based Relaxation Training and Symptom Improvement Among Inpatients With Depressive Disorders: Retrospective Nonrandomized Comparative Study.

BACKGROUND: Virtual reality (VR) is increasingly used for adjunctive relaxation training in psychiatric care. However, evidence remains limited among hospitalized patients with depressive disorders, particularly in routine inpatient settings in China, and little is known about whether improvement varies by session frequency. OBJECTIVE: This retrospective study examined whether adjunctive VR-based relaxation training was associated with changes in depressive and anxiety symptoms among inpatients with depressive disorders and whether improvement differed by session frequency. METHODS: We condu…

Cross-Lagged Dyadic Associations of Food Insecurity and Depressive Symptoms among Couples Living with HIV and Cardiometabolic Disorders in Malawi.

BACKGROUND: Household food insecurity is an important social determinant of mental health, human immunodeficiency virus (HIV), and cardiometabolic outcomes in sub-Saharan Africa. Research is limited on how couples managing chronic illness are jointly affected by household food insecurity and depressive symptoms. OBJECTIVES: The aim of our study was to investigate whether household food insecurity predicts subsequent depressive symptoms over time among couples living with HIV and cardiometabolic disorders in Malawi. METHODS: We examined longitudinal dyadic data (4 waves) from 250 couples recr

Correction: Anxiety and depressive disorders in adolescent injury prevention and safety promotion: frontier and inequality mapping across 953 locations.

[This corrects the article DOI: 10.3389/fpubh.2026.1916777.].

Higher suicidality among primary care patients who have opioid use disorder and co-occurring depression and/or PTSD.

BACKGROUND: Depression and/or posttraumatic stress disorder (PTSD) commonly co-occur with opioid use disorder (OUD), and such co-occurring disorders (COD) are especially common among patients in primary care settings. Therefore, addressing the mental health needs of people with COD in primary care is essential. METHODS: We compared the characteristics of three groups of patients who screened positive for OUD and depression and/or PTSD: (OUD + depression, OUD + PTSD, and OUD + depression + PTSD) and examined how membership in these groups was associated with suicidality and treatment. We analyz

Scalp electroacupuncture targeting trigeminal nerve activation alleviates post-traumatic stress disorder-induced depression and neuroinflammation in mice.

BACKGROUND: Scalp electroacupuncture (SA) has been clinically used as a novel treatment for ischemic stroke and depression. This study aimed to investigate whether stimulation of SA of the Baihui (GV20) and Yintang (EX-HN3) acupoints, which regulate the trigeminal nerve (TN), can alleviate depression and anxiety caused by post-traumatic stress disorder (PTSD) and to identify its therapeutic mechanism. METHODS: After stimulation of SA, vasodilation and leakage within the TN area and c-Fos expression in the TN pathway of the brain were analyzed. Also, the anti-inflammatory, antidepressant, and

Psychosocial impact of chronic oral mucosal pain disorders: Associations with oral health related quality of life, anxiety, and depression.

BACKGROUND: Chronic oral mucosal pain disorders, including Burning Mouth Syndrome (BMS), Oral Lichen Planus (OLP), Atypical Odontalgia, and Persistent Idiopathic Facial Pain, are debilitating conditions that significantly impair oral health-related quality of life (OHRQoL). These disorders are frequently associated with psychological distress, particularly anxiety and depression; however, studies integrating assessments of OHRQoL with psychological morbidity remain limited. OBJECTIVE: To evaluate the impact of chronic oral mucosal pain disorders on OHRQoL, anxiety, and depression, and to iden

Mindfulness-based exposure and response prevention in individuals with comorbid obsessive-compulsive and major depressive disorders: a randomized controlled trial.

This randomized controlled trial examined whether mindfulness-based exposure and response prevention (MB-EX/RP) improves outcomes for adults with comorbid obsessive-compulsive disorder (OCD) and major depressive disorder (M, addressing cognitive rigidity and emotion dysregulation that can limit standard exposure and response prevention. Fifty-four participants were assigned to MB-EX/RP or standard exposure and response prevention; 40 completed treatment (20 per group) across 17 sessions. OCD symptom severity, as measured by the Yale-Brown Obsessive Compulsive Scale (Y-BOCS), showed a significa…

Gut-brain axis: biological correlations between inflammatory bowel disease and anxiety or depressive disorders - a scoping review of reviews.

OBJECTIVE: The bidirectional communication between the nervous system and the gastrointestinal tract plays a crucial role in maintaining homeostatic balance.The present study aims to understand the gut-brain axis and how this complex interaction relates to inflammatory bowel disease and the development of anxious and depressive symptoms. METHOD: The search for articles was conducted in the MEDLINE, LILACS, and Cochrane databases. Reviews published between 2009 and 2025 that addressed the gut-brain interaction with a focus on the development of inflammatory bowel disease (IBD) and anxious and/o

Depressive symptoms and their gastrointestinal correlates: A nationwide observational study in the Chinese middle-aged and elderly population with nonmalignant gastrointestinal disorders.

The pathophysiological interplay between depressive symptoms and benign upper gastrointestinal (UGI) disorders encompassing peptic ulcer disease, gastritis, duodenitis, and gastroesophageal reflux disease remains incompletely defined. These chronic inflammatory conditions impose a substantial health burden on Chinese middle-aged and elderly adults, yet the temporal relationship linking depressive symptomatology to disease onset remains underexplored. This nationally representative cohort study seeks to address this critical knowledge gap through longitudinal analysis. This national population-

Anxiety-Depressive Disorders in 200 Patients with Post-COVID-19 Syndrome: Prevalence and Predictors from a Cross-Sectional Study.

Background and Objectives: Recovering from COVID-19 does not always imply a full return to health and may lead to the development of post-COVID-19 syndrome. Post-COVID-19 manifestations include, among others, symptoms of depression and/or anxiety. The aim of the study was to assess the prevalence of anxiety and depressive disorders and to identify their exogenous and endogenous predictors in individuals with post-COVID-19 syndrome. Materials and Methods: The study included 200 participants (116 women and 84 men, aged 18-80) diagnosed with post-COVID-19 syndrome. Participants completed psycholo…

Differential trajectories of depression symptoms during pregnancy and prospective associations with postpartum eating disorder symptoms and cardiovascular health behaviors.

PURPOSE: Approximately one-in-ten individuals experience depression during pregnancy, a period marked by considerable biopsychosocial change. Prior research has investigated perinatal depressive symptom change and identified links to negative health outcomes, such as hypertension and delivery complications. However, it is unknown if these findings extend to pregnant people with higher weight, who may have increased risk. Additionally, understanding how depression experiences during pregnancy impact postpartum eating disorder (ED) symptoms and cardiovascular health behaviors can provide insight

Эффективность применения цифровых технологий для лечения депрессии и общего тревожного расстройства в Германии, отвечающих установленным требованиям: систематический обзор и метаанализ.

В Германии были внедрены цифровые прикладные программы в области психического здоровья, отвечающие установленным требованиям (ДИГ) 2020 в качестве многообещающих мероприятий, направленных, в частности, на борьбу с депрессией и расстройствами, вызывающими тревогу, two - наиболее распространенных в мире психических заболеваний. Несмотря на растущий интерес к ДИГ, их общая эффективность остается неопределенной. Это исследование было направлено на систематическую оценку и количественную оценку эффективности требуемых по рецепту цифровых средств для лечения депрессии и общего тревожного расстройств

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… “Depressive disorders prevalence” [dataset]. IHME, Global Burden of Disease, “Global Burden of Disease - Mental Health Prevalence” [original data]. Available at https://archive.ourworldindata.org/20250624-125417/grapher/depressive-disorders-prevalence-ihme.html (2024). 2. … Efficacy of a Web-Based Intervention for Depressive Disorders: Three-Arm Randomized Controlled Trial Comparing Guided and Unguided Self-Help With Waitlist Control. JMIR Form Res. 6 , e34330. 10.2196/34330 (2022). 43. Berger, T. et al. …

Metabolomics revealed that quercetin improved spleen metabolism disorders and regulated the brain-spleen axis in perimenopausal depression model rats.

Perimenopausal depression is a subtype of depression that seriously harms women's health. The pathogenesis of perimenopausal depression remains unclear, which limits its prevention and therapy. Quercetin is a flavonoid with antidepressant and estrogen-like effects. This study aimed to explore the effects of quercetin on spleen metabolism in rats with perimenopausal depression and its potential mechanism. Untargeted metabolomics was employed to obtain splenic metabolite profiles, and 21 differential metabolites were identified. Pathway analysis revealed that glycerophospholipid metabolism, reti

Mediating effect of occupational stress between skeletal muscle disorders and depressive symptoms in firefighters: a Structural Equation Modeling approach.

OBJECTIVES: The purpose of this study was to explore the relationship between skeletal muscle disorders (SMD), occupational stress (OS) and depressive symptoms (DS) among firefighters. MATERIAL AND METHODS: A cross-sectional survey was conducted among firefighters in Chongqing, China. Descriptive statistic and correlation analyses were performed by using SPSS 26.0. AMOS 24.0 was used to construct the structural equation modeling between SMD and DS. The mediating effect of OS was also evaluated. RESULTS: The results demonstrate that SMD can predict DS (β = 0.25, p < 0.001) and OS (β = 0.39, p

Activation Likelihood Estimation Meta-Analysis of the Effects of Cognitive Behavioral Therapy on Brain Activation in the Treatment of Depression and Anxiety Disorders.

Background: Cognitive behavioral therapy (CBT) stands as a highly efficacious psychological treatment for both anxiety and depressive disorders. Nonetheless, scholarly debates persist regarding the specificities of brain area activation during CBT treatment for these disorders. Methodology: Utilizing activation likelihood estimation (ALE) analysis, this study aims to discern the neurobiological similarities and disparities between CBT's effects on anxiety and depressive disorders by examining functional brain areas. Results: A total of 22 articles, encompassing 443 patients, were included in t…

The effectiveness of the Chinese Five-Element Music intervention on older adults with depression and anxiety disorder: A systematic review and meta-analysis.

BACKGROUND: Depression and anxiety are among the most prevalent mood disorders worldwide, affecting hundreds of millions of people and contributing to significant disability, particularly in older adults. Conventional treatments such as pharmacotherapy and psychotherapy are effective but often limited by side effects or accessibility. As a complementary approach, Chinese Five-Element Music (CFEM), rooted in Traditional Chinese Medicine, aims to restore emotional balance through the connection between musical tones, organ systems, and emotions. Recent studies suggest its potential to alleviate

The Relationship Between Early Pregnancy Depression, Social Support, and Hypertensive Disorders of Pregnancy: A Prospective Cohort Study in Xuzhou, China.

BACKGROUND: Hypertensive disorders of pregnancy (HDP) are major causes of maternal-neonatal morbidity/mortality. Emerging evidence links early pregnancy depression to HDP, but the interaction of social support, including its potential mediating and moderating roles remains understudied. This prospective cohort study explored the associations between early pregnancy depression, social support, and HDP risk in Xuzhou, China. METHODS: A cohort of 1,406 pregnant women at ≤12weeks gestation were recruited from a hospital in Xuzhou, China, between July 2024 and July 2025. Depression symptoms and so

The Depression, Anxiety, Stress Scales-21: Principal component analysis and evaluation of abbreviated versions in young adults with temporomandibular disorders.

BACKGROUND: The Depression, Anxiety, Stress Scales-21 (DASS-21) contain three subscales measuring depression, anxiety, and stress. Several abbreviated DASS-21 versions have been developed, demonstrating better clinical utility and measurement properties than the original instrument. This study explored the factor structure of various abbreviated DASS-21 versions and identified/validated the optimal one for assessing young adults with temporomandibular disorders (TMDs). METHODS: A total of 974 university-attending young adults were recruited in two waves (wave 1: 519; wave 2: 455). Demographic

The relationship between regional homogeneity in resting-state functional magnetic resonance imaging and cognitive function in depressive disorders with migraine.

Patients with depressive disorder with migraine (DDWM) are common, yet the neural mechanisms and brain function changes associated with this comorbidity remain partially understood. This study explores regional homogeneity (ReHo) abnormalities in resting-state functional magnetic resonance imaging (fMRI) and cognitive function in DDWM patients. We recruited 29 patients with DDWM, 34 patients with depressive disorder without migraine (DDWOM), and 43 matched healthy controls (HC). All participants underwent rs-fMRI scans, and imaging data were analyzed using ReHo. Cognitive function was assessed…