Результаты поиска

Vaccine tolerance in steroid substituted patients with congenital adrenal hyperplasia.

The tolerance and side effects of vaccinations were determined in patients with congenital adrenal hyperplasia (CAH) who receive physiologic … 78%, respectively, whereas pertussis vaccination was complete in only 23%. Live vaccination against measles, mumps and rubella was performed in 63%, 50% and 38%. Side effects of vaccination were indicated in 5 out of 82 questionnaires who all belonged to CAH patients with salt-losing. Transient side effects were an anaphylactic reaction, probably to tetan …

School health nurse interventions to increase immunisation uptake in school entrants.

In New South Wales, health screening of school entrants provides the only mechanism for routine monitoring of immunisation uptake in children. School health nurses are in the best position to improve the compliance with immunisation at this age. We compared two interventions to be used by the nurses to increase immunisation uptake in school entrants who reported missing either the measles-mumps vaccine and/or the pre-school diphtheria-tetanus toxoid and oral polio vaccine boosters. Parents in the passive intervention group were sent a letter and leaflet encouraging immunisation; the active int…

Immunisation practices of general practitioners in metropolitan Sydney.

An anonymous postal survey of all known general practitioners in the Northern Sydney Health Area (N = 987) examined the provision of immunisation services in general practice. Questions were asked about knowledge of storage of vaccines, the ages of patients administered measles-mumps-rubella vaccine, the use of reminder systems for subsequent vaccinations and whether maternal and family health was discussed at immunisation visits. There were 394 (40 per cent) respondents. Only 30 per cent used temperature monitors in their vaccine refrigerators, and 26 per cent correctly identified the period …

Vitamin A supplementation and child mortality. A meta-analysis.

OBJECTIVE: A two-part meta-analysis of studies examining the relationship of vitamin A supplementation and child mortality. DATA SOURCES: W … ssignment of treatment groups in community-based studies. Vitamin A supplementation to hospitalized measles patients was highly protective against mortality (DerSimonian and Laird odds ratio, 0.39; 95% confidence interval, 0.22 to 0.66; P = .0004) (part 1 of the meta-analysis). Supplementation was also protective against overall mortality in community-bas …

Serum amyloid A protein in acute viral infections.

Concentrations of serum amyloid A protein (SAA) were measured in 254 children with viral diseases, including measles, varicella, rubella, mumps, echo-30 meningitis, chronic hepatitis B and C, and in eight with Kawasaki disease. Latex agglutination nephelometric immunoassay was used for assaying SAA. In 191 out of 195 patients (98%), SAA concentrations became markedly raised in the acute phase of the viral disease: measles (97%), varicella (100%), mumps (95%), and echo-30 meningitis (99%) with mean titres of 82.4, 80.5, 60.2, 75.2, and 101.1 micrograms/ml respectively. This increase in SAA was …

Seasonality and the requirements for perpetuation and eradication of viruses in populations.

Perpetuation of a virus in a population is distinct from the ability to persist in a cell culture or individual host. Parameters which deter … ulation size in which persistence is possible, and we argue that the population size of 500,000 for measles persistence (described by Bartlett) is primarily a consequence of seasonal variation. Computer modelling can be used to examine the effect of changes in parameters which determine the seasonal cycle of virus perpetuation and fadeout. Finally, human …

Subacute sclerosing panencephalitis virus in immunosuppressed adult hamster.

A hamster-adapted subacute sclerosing panencephalitis agent (HBS virus) produced a subclinical, nonlethal, and cell-associated encephalitis … t anti-hamster lymphocyte serum treatment, those surviving for 21 to 54 days always displayed serum measles antibodies, and, from such animals, highly cell-associated virus could often be isolated from the brain. In such animals and in some others from which no virus could be isolated, the presence of measles antigen or inclusion cell pathology was noted …

Global, regional, and national impact of the Expanded Programme on Immunization against 14 pathogens from 1974 to 2024: an economic evaluation.

BACKGROUND: 2024 marked the 50th anniversary of the Expanded Programme on Immunization (EPI), launched by WHO. Despite its crucial role in p … enzae type b, hepatitis B virus (hepatitis B), Japanese encephalitis virus (Japanese encephalitis), measles virus (measles), Neisseria meningitidis group A (meningitis A), Streptococcus pneumoniae, Bordetella pertussis (pertussis), poliovirus (polio), rotavirus, rubella virus (rubella), Clostridium tetani (tetanus), Mycobacterium tuberculosis (tuberculosi …

How to Increase Vaccination Acceptance Among Apostolic Communities: Quantitative Results from an Assessment in Three Provinces in Zimbabwe.

A worldwide increasing trend toward vaccine hesitancy has been reported. Measles outbreaks in southern Africa in 2009-2010 were linked to objections originating from Apostolic gatherings. Founded in Zimbabwe in the 1950s, the Apostolic church has built up a large number of followers with an estimated 3.5 million in Zimbabwe in 2014. To inform planning of interventions for the 2015 measles-rubella vaccination campaign, we assessed vaccination status and knowledge, attitudes and practices among purposive samples of Apostolic caregivers in three districts each in Harare City, Manicaland and Matab…

Viral infection in patients with multiple sclerosis and HLA-DR matched controls.

Retrospective comparisons of the prevalence and age, where appropriate, of some childhood infectious illnesses and vaccinations, together wi … s the effect of HLA type itself on the results. Patients with demyelinating disease had rubella and measles at a later age and reported mumps infection more frequently than controls. Age of typhoid vaccination and duration of exposure to domestic dogs was higher in all cases than controls. Age of measles and mumps, but not rubella, was higher in DR2+ case …

Infectious contamination of healthcare workers.

BACKGROUND: Infectious diseases represent a major component of biological hazards encountered by healthcare workers. Occupational exposure m … rs may be exposed to a wide spectrum of infectious agents including respiratory viruses (influenza, measles, tuberculosis), contact transmitted pathogens (scabies, cytomegalovirus), enteric infections (hepatitis A), and blood borne viruses such as hepatitis B, hepatitis C, and human immunodeficiency virus. Transmission risk depends on the interaction betw …

The Relationship Between Political Affiliation, Perceptions of Science and Scientists, and Perceived Safety and Effectiveness of the MMR, Flu, and COVID-19 Vaccines: United States, 2024.

Objectives. To examine the associations between political party identification, perceptions of science and scientists, and perceived safety and effectiveness of the measles, mumps, and rubella, flu, and COVID-19 vaccines. Methods. We used multiple regression analyses to examine survey data collected in November 2024 from a national probability sample of 1763 US adults. We measured perceptions of science and scientists using the Factors Assessing Science's Self-Presentation (FASS) scale, which assesses beliefs that scientists are credible, prudent, and unbiased and that science is beneficial an…

Persistent immunological repercussions of late antiretroviral initiation in children with HIV.

OBJECTIVE: We aimed to evaluate how age at antiretroviral treatment (ART) initiation modified immune parameters and vaccine responses in a Brazilian cohort of children with perinatally acquired HIV on long-term treatment. DESIGN: Cross-sectional study including children <18 years; ART for ≥6 months; and HIV viral load <50 copies/ml. METHODS: Data was abstracted from medical charts and blood was collected for serology and PBMC isolation. Antibody titers for hepatitis A and B, rubella, mumps and measles were measured. T cells with markers for senescence (CD57 + ), anergy (CD28 - ), apoptosis (…

Adding Virome Capture Metagenomic Sequencing to Conventional Laboratory Testing Increases Unknown Fever Etiology Determination in Bamako, Mali.

Unexplained fever poses significant diagnostic challenges in resource-limited settings like Bamako, Mali, where overlapping endemic diseases … rCapSeq-VERT]). Among 108 enrolled subjects, most were male (51.9%) and under 15 years old (56.5%). Measles virus was identified in 39.8% of cases, primarily among children. Other findings included Plasmodium spp. (12%), Salmonella spp. (13%), and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2; 8.7%). The virome capture sequencing platform fo …

Childhood MMR Vaccination Effectiveness Against Rubella: A Longitudinal Cohort Study.

The vaccine effectiveness (VE) of childhood measles-mumps-rubella (MMR) vaccine to reduce childhood rubella infections in the US during the 1990s/2000s was undertaken in a retrospective longitudinal cohort study. SAS and StatsDirect software were utilized to examine non-identifiable linked eligibility and claim healthcare records prospectively generated from the Florida Medicaid system in the Independent Healthcare Research Database (IHRD). A total of 33 839 children received a single MMR vaccination (vaccinated) and 44 154 children never received a rubella-containing vaccine (unvaccinated) we…

В рамках расширенной программы иммунизации детей горных племен в Таиланде: перекрестное исследование.

СПРАВОЧНАЯ ИНФОРМАЦИЯ: Расширенные программы иммунизации (ПИИ) представляют собой программы вакцинации для конкретных стран, разработанные и осуществляемые в целях профилактики детских заболеваний во всем мире, в том числе в Таиланде. Дети горных племен в Таиланде живут в отдаленных районах с недостаточно развитыми системами образования и низким экономическим статусом. Цель этого исследования состояла в том, чтобы оценить серопокрытие в рамках ЭПИ и доступ к клиникам вакцинации. МЕТОДЫ: Было проведено перекрестное исследование для оценки серопокрытия после вакцинации детей из числа горных плем

Совпадение в аннотации оригинала
BACKGROUND: Expanded programs on immunization (EPIs) are country-specific vaccine programs designed and implemented to prevent childhood dis … ed. Antibodies against hepatitis B surface antigen (anti-HBs), hepatitis B core antigen (anti-HBc), measles, Japanese encephalitis virus (JEV), and tetanus were detected. Chi-square tests were performed to detect the different proportion of patients with antibodies with different characteristics. RESULTS: Half of the hill tribe children aged 1-18 years d …

Vaccination policies among health professional schools: evidence of immunity and allowance of vaccination exemptions.

OBJECTIVE To characterize health professional schools by their vaccination policies for acceptable forms of evidence of immunity and exemptions permitted. METHODS Data were collected between September 2011 and April 2012 using an Internet-based survey e-mailed to selected types of accredited health professional programs. Schools were identified through accrediting associations for each type of health professional program. Analysis was limited to schools requiring ≥1 vaccine recommended by the Advisory Committee on Immunization Practices (ACIP): measles, mumps, rubella, hepatitis B, varicella, …

Seroprevalence of rubella in female migrant factory workers in Shenzhen, China.

BACKGROUND: Rubella remains a common disease in Mainland China and is a major cause of severe birth defects from Congenital Rubella Syndrome … on region of origin, being without a job contract, age group, marital status and seronegativity of measles. CONCLUSIONS: Seroprevalence of antibodies to rubella in Shenzhen, China amongst female migrant workers is too low to provide immunity in the population. Given the high numbers of women of childbearing age amongst Shenzhen migrant factory workers c …

Aseptic meningitis in a large MMR vaccine campaign (590,609 people) in Curitiba, Paraná, Brazil, 1998.

The aseptic meningitis after Measles-Mumps-Rubella vaccine (MMR) is a well recognized complication, and different incidences have been observed in several studies. We retrospectively analyzed forty cases of aseptic meningitis, during a large public immunization campaign (1998) in Curitiba, Southern Brazil (590,609 people), admitted in our Service. The vaccine utilized was Leningrad-3-Zagreb mumps strain, Edmonston-Zagreb measles strain, and RA 27#3 rubella strain. In all county, a total number of 87 cases were reported, resulting in a incidence of 1.7 cases per 10,000 given doses. The mean age…

Adult immunizations--a practical approach for clinicians: Part I.

Vaccine-preventable diseases cause needless sickness and death in adult Americans. Most adults 65 years of age or older have not been immunized against influenza or pneumococcal disease. In addition to an age of 65 years or older, indications for influenza and pneumococcal vaccines include chronic obstructive pulmonary disease, hemodynamically significant cardiac disease and infection with the human immunodeficiency virus. Many adults in the United States also are not sufficiently protected against tetanus, diphtheria, measles, mumps and rubella.