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Safety of the fourth COVID-19 BNT162b2 mRNA (second booster) vaccine: a prospective and retrospective cohort study.

BACKGROUND: The effectiveness of the second BNT162b2 (Pfizer-BioNTech) mRNA COVID-19 booster vaccine dose (ie, fourth inoculation) is well e … 18 years or older, members of Maccabi Healthcare Services at the time of enrolment, using their own smartphone, and be able to give informed consent by themselves. Participants from the prospective cohort received smartwatches, downloaded a dedicated mobile application, and granted access to their medical records. The smartwatches continuously monitored seve …

The impact of mHealth interventions on medication adherence in breast cancer: a systematic review of randomized controlled trials.

BackgroundNon-adherence to medication can reduce therapeutic effectiveness in breast cancer patients, thereby increasing the risk of disease progression or recurrence. This study aimed to systematically review the existing scientific literature on the impact of mHealth interventions on medication adherence among breast cancer patients.MethodsThis systematic review was conducted following PRISMA guidelines and focused on randomised clinical trials published in English. The review evaluated the effectiveness of mHealth interventions in improving medication adherence in breast cancer patients fro

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… We predict that this intervention, along with other smartphone interventions, will be used frequently for medication adherence. … Adherence assessment methods varied across studies, including smartphone records, self-reported questionnaires, and biomarkers. …

От удобства использования до клинического воздействия: систематический обзор цифровых технологий для реабилитации движений у пациентов с множественной скlerозом.

ОБЪЕКТ: Систематический обзор удобства использования, приемлемости и предварительного клинического влияния цифровых интервенций по восстановлению двигательной функции в группе людей с множественной склерозом (ПМС).МЕТОДЫ: Систематический поиск литературы был проведен в PubMed, Scopus, Embase и Web of Science до июня 2025 года для идентификации исследований, оценивающих удобство использования в контексте цифровых платформ, используемых для моторной реабилитации. Включены только исследования, участвовавшие в pwMS. РЕЗУЛЬТАТЫ: Включено девять исследований. Вмешательства использовали кинетон-бази

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… In this regard, emerging digital technologies, including wearable sensors, smartphone applications, and exergames, offer promising means to promote physical activity in pwMS ( 11 ). … Nasseri et al., (2020) ( 25 ) | Pilot RCT | 38 pwMS | 3 months | Samsung s-4 mini, smartphone app | To investigate the feasibility of a smartphone application to improve physical activity in people with chronic progressive multiple sclerosis. | The intervention group received access to a smartphone application …

New Technologies and Digital Health Tools in Patients With Solid Tumors and Hematological Malignancies: Cross-Sectional Multicenter Survey Study.

BackgroundBarriers to eHealth use include lack of technological infrastructure, resistance to change, and inequities in access. However, patterns of access to and use of eHealth tools in people being treated for cancer have not been fully described in the literature.ObjectiveOur aim was to describe the patterns of access to and use of eHealth tools among outpatients receiving treatment for hematological malignancies and solid tumors.MethodsWe conducted a cross-sectional multicenter study using a survey offered to patients aged over 18 years receiving outpatient treatment for hematological mali

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… | 172 (86) Wearable | 81 (40.5) Internet access, n (%) Computer | 118 (59) Tablet | 68 (34) Smartphone | 166 (83) Health research on the internet | 85 (42.5) Preference to communicate with medical team, n (%) Smartphone | 90 (45) Email | 42 (21) App | 26 (13) Video call | 24 (12) Notably, 172 (86%) … of the 200 patients owned smartphones, and 81 (40.5%) participants owned wearable devices. …

Assessing the performances of a chatbot to collect real-life data of patients suffering from primary headache disorders.

BackgroundThere are many scales for screening the impact of a disease. These scales are generally used to diagnose or assess the type and severity of a disease and are carried out by doctors. The chatbot helps patients suffering from primary headache disorders through personalized text messages. It could be used to collect patient-reported outcomes.ObjectiveThe aims of this study were (1) to study whether the collection and analysis of remote scores, without prior medical intervention, are possible by a chatbot, (2) to perform suggested diagnosis and define the type of headaches, and (3) to as

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… Regarding the subdivision of the migraine patient, no significant differences were found due to the age, the level of study, nor the smartphone/computer usage time over a day ( P- value were, respectively, P = .203>.05; P = .293>.05; P = .925>.05). … A smartphone Chatbot application to optimize monitoring of older patients with cancer. Int J Med Inform 2019; 128: 18–23. Epub 2019 May 14. …

A Pilot Study to Evaluate a Residual Inhibition Technique in Hearing Aids for Suppression of Tinnitus.

Tinnitus acoustic therapy is defined as any use of sound where the intent is to alter the tinnitus perception and/or the reactions to tinnit … and creating an individualized residual inhibition stimulus that was streamed via Bluetooth from a smartphone application to the hearing aids. The participants were instructed to wear the hearing aids and stream the residual inhibition stimulus all waking hours for the 2-month intervention period. During the wash-out period, the participants were instructed …

Development and early feasibility testing of machine-learning algorithms to non-invasively assess hemoglobin levels.

The HeMonitor study evaluated the feasibility and accuracy of non-invasive hemoglobin (Hb) assessment using image-based techniques and machine learning in patients with hematologic malignancies. A total of 367 patients with hematologic malignancies and 184 healśśthy donors were enrolled, with fingernail and eyelid photographs collected and analyzed using Light Gradient-Boosting Machine (LightGBM) regression models. The best-performing model achieved a residual standard deviation of ±1.02 mmol/L for Hb prediction. Our framework further explored a two-stage concept combining (i) a non-invasive i

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… Several groups have explored smartphone-based and computer vision methods for Hb estimation. Wang et al. introduced HemaApp 1 , a smartphone application designed to non-invasively estimate Hb levels using the device camera and multiple light sources to analyze blood color in the user’s finger. … In the SmartHeLP study by Hasan et al., artificial neural networks (ANNs) were used to estimate Hb levels from smartphone-based fingertip imaging 3 . …

Effect of a Mobile App for the Pharmacotherapeutic Follow-Up of Patients With Cancer on Their Health Outcomes: Quasi-Experimental Study.

BackgroundOral antineoplastic agents (OAAs) have revolutionized cancer management. However, they have been reported with adverse side effects and drug-drug interactions. Moreover, patient adherence to OAA treatment is critical. Mobile apps can enable remote and real-time pharmacotherapeutic monitoring of patients, while also promoting patient autonomy in their health care.ObjectiveThe primary objective was to analyze the effect of using a mobile app for the follow-up of patients with oncohematological malignancies undergoing treatment with OAAs on their health outcomes. The secondary objective

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… Patients had to have a smartphone and were followed up daily through an app (e-OncoSalud) for 6 months from the start of the treatment. … In the intervention group, 111 patients started treatment but 61 patients were excluded (40 for not completing the follow-up period and 21 for not having a smartphone). …

Цифровые симптомы, сообщающие о готовности к лечению до Даратумумаба: слепое перспективное исследование в Множественной миеломе.

Цели: Для пациентов с множественной миеломой (ММ) в настоящее время все большая часть лечения оказывается на дому. Хотя такая смена обеспечивает удобство и способствует непрерывному уходу, она также требует новых путей обеспечения безопасности пациентов вне больницы. Хотя пациенты, проходящие лечение на дому, как правило, являются клинически стабильными, каждая администрация по-прежнему нуждается в предварительной оценке безопасности, которая традиционно проводится по телефону. Мы стремились оценить, могут ли результаты, о которых сообщают пациенты в цифровой форме, заменить эти звонки для опр

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… Patients eligible for inclusion were adults (>18 years), had a diagnosis of relapsed MM, were in possession of a smartphone or computer, and were planning to start or were already in treatment with daratumumab. … A smartphone app to improve the safety of patients undergoing treatment with oral antineoplastic agents: 4 years of experience in a university hospital. Front. …

Developments in Point-of-Care Diagnostic Technology for Cancer Detection.

Cancer is the cause of death for one in seven individuals worldwide. It is widely acknowledged that screening and early diagnosis are of vital importance for improving the likelihood of recovery. However, given the costly, time-consuming, and invasive nature of the many methods currently in use, patients often do not take advantage of the services available to them. Consequently, many researchers are exploring the possibility of developing fast, reliable, and non-invasive diagnostic tools that can be used directly or by local physicians at the point-of-care. Herein, we look at the use of estab

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… The authors address the tremendous need for mobile diagnostic platforms and focused their effort on the development of a miniaturized smartphone-based spectrometer. … Recent approaches for optical smartphone sensing in resource-limited settings: A brief review. Anal. Methods. 2016;8:6591–6601. doi: 10.1039/C6AY01575A. 111. Wang L.-J., Chang Y.-C., Sun R., Li L. A multichannel smartphone optical biosensor for high-throughput point-of-care diagnostics. Biosens. …

Remote vital signs data monitoring during home blood transfusion: A pilot study.

BACKGROUND AND AIMS: Our study aimed to establish safer methods to manage home blood transfusion by using a remote vital signs data monitoring system. Home care is administered for patients with various medical disorders; however, home blood transfusion remains challenging owing to the risk of transfusion-related complications. METHODS: We set up a remote vital signs data monitoring system to improve the safety of home blood transfusions. Using an Internet-based vital signs data monitoring system, the heart rate, electrocardiography, respiration rate, and percutaneous oxygen saturation (SpO2)

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… Measurement data can be monitored in real time on a smartphone from a remote location via the Internet. FIGURE 1 Real‐time remote monitoring system. … When the attendant calls the doctor, they assess the patients' vital signs on the smartphone and take appropriate action as per the patient's condition. …

EUROPAEM EMF Guideline 2016 for the prevention, diagnosis and treatment of EMF-related health problems and illnesses.

Chronic diseases and illnesses associated with non-specific symptoms are on the rise. In addition to chronic stress in social and work envir … z) is emitted from radio and TV broadcast antennas, Wi-Fi access points, routers, and clients (e.g. smartphones, tablets), cordless and mobile phones including their base stations, and Bluetooth devices. Extremely low frequency electric (ELF EF) and magnetic fields (ELF MF) (3 Hz to 3 kHz) are emitted from electrical wiring, lamps, and appliances. Very low f …

Convenient Access to Expert-Reviewed Health Information via an Alexa Voice Assistant Skill for Patients With Multiple Myeloma: Development Study.

BackgroundPatients with multiple myeloma (MM) have high information needs due to the complexity of the disease and variety of treatments. Digital voice assistants provide support in daily life and can be a convenient tool that even older patients can use to access health information. Voice assistants may therefore be useful in providing digital health services to meet the information needs of patients with MM.ObjectiveWe aim to describe and report on the development, content, and functionality of the first Amazon Alexa voice assistant skill for patients with MM in Germany with the goal of empo

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… Alexa skills can be used with devices featuring Amazon Alexa (eg, Amazon smart speakers or smart televisions [TVs]) or with any smartphone that has the Amazon Alexa app and the integrated Alexa voice assistant. … The Alexa skill Multiple Myeloma can be used with different devices, including smart speakers and smart TVs, and with smartphones by using the Amazon Alexa app with the integrated Alexa voice assistant. …

Recent advances in the detection and management of motor dysfunction in Alzheimer's disease.

Alzheimer's disease (AD) is a progressive neurodegenerative disorder primarily characterized by cognitive decline. However, there is growing … potentially enabling earlier and more accurate diagnoses. Digital tools and applications-including smartphone-based assessments and virtual reality platforms-are being explored for objective and quantitative evaluation of mobility. These digital measures offer the potential for longitudinal data collection and the detection of subtle changes in motor functi …

Design and implementation of mHealth applications for older people with cancer: A scoping review.

ObjectiveThis scoping review aimed to systematically synthesize the evidence on the functions, design, implementation strategies, and evaluation approaches of mobile health (mHealth) applications (apps) developed for older adults with cancer, to inform future research and practice.MethodsA scoping review was conducted using Arksey and O'Malley's methodological framework, with an updated systematic search of five databases (Medline, Web of Science, CINAHL, Embase, and the Cochrane Library) from January 1, 2008, to February 28, 2025. The review adhered to the PRISMA-ScR guidelines for scoping re

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… It provides medical information and services to people through smart mobile devices, with smartphone apps being the most popular and widespread. 5 Smartphones are portable, and mHealth apps allows users to monitor their physical conditions and help people get immediate feedback from specialized persons … Beta testing a novel smartphone application to improve medication adherence. Telemed J e Health. Apr 2017;23(4):339–348. doi: 10.1089/tmj.2016.0100. 78. Wildenbos G.A., Peute L., Jaspers M. …

Экологическая оценка ежедневной деятельности лиц с неврологическими расстройствами: обзор.

Ежедневная деятельность определяет состояние здоровья и благополучие людей, отражая функционирование и состояние здоровья. Для людей с неврологическими расстройствами эта деятельность часто нарушается, что сказывается на автономности и качестве жизни. Традиционные оценки не учитывают тонкие колебания в режиме реального времени, в то время как экологическая временная оценка (ЕМА) охватывает деятельность < < момент-момент > > в естественном контексте, что позволяет глубже понять взаимосвязи между человеком, окружающей средой и профессиональной деятельностью. Несмотря на все более шир

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… In recent years, advances in digital health technologies have enabled more objective approaches to capturing aspects of daily behavior, such as mobility tracking, sensor-based monitoring, and smartphone interaction data [ 22 ]. … EMA typically involves repeated assessments administered multiple times per day over several days or weeks, often delivered via smartphone-based apps or other digital devices. …

Usability testing of an electronic patient-reported outcome system linked to an electronic chemotherapy prescribing and patient management system for patients with cancer.

BackgroundPeople affected by cancer experience a wide range of symptoms which have a major impact on their functioning and health-related quality of life (HRQoL). One way to measure the impact of cancer symptoms is through the use of patient-reported outcomes.MethodsAn electronic patient-reported outcome (ePRO) application (ChemoPRO®) was designed to be used by cancer patients to report their symptoms and communicate with their clinical team. Usability testing sessions were conducted with people with lived experience of cancer to understand how real users interact with the ChemoPRO® system. On

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… This may be due to the fact that more older people are using smartphones on a regular basis and that smartphones facilitate digital communication [ 30 ]. … Smartphone Internet access and use: extending the digital divide and usage gap. Mob. Media Commun. 2017;5(3):239–255. 31. Aiyegbusi O.L., et al. Key considerations to reduce or address respondent burden in patient-reported outcome (PRO) data collection. Nat. …

PB2343: MONITORING PHYSICAL ACTIVITY OF OLDER ADULTS WITH HEMATOLOGICAL MALIGNANCIES. THE IMPORTANCE OF CONDUCTING AN INDIVIDUALIZED FOLLOW-UP PROGRAM TO PREVENT FUNCTIONAL IMPAIRMENT

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… The exclusion criteria were life expectancy less than one month, not indication of treatment, absence of smartphone, or program refusal. Initially, a CGA was made jointly between the geriatrician and the geriatric nurse. All those patients who fit the criteria were included in the program. … The main diagnosis were: lymphoma (38%), multiple myeloma (32%), and chronic lymphatic leukemia (21%). 20 patients (59%) were classified as fit, 11 (32%) as pre-fragile, 2 (6%) as fragile, and 1 (3%) as “poor prognosis”. 33% were excluded (3 absence of smartphone, 2 life expectancy < 1 month, 4 refusal …

Искусственные интеллектуальные технологии зондирования для борьбы с раком, диабетом и COVID-19.

Интеграция искусственного интеллекта (АИ) с износимыми сенсорными технологиями может привести к революции в мониторинге и лечении различных хронических заболеваний и острых заболеваний. Комбинированные износы АИ классифицируются по таким основополагающим методам зондирования, как электрохимическая, колориметрическая, химическая, оптическая, а также давление/стабильность. Алгоритмы АИ повышают эффективность изношенных датчиков, обеспечивая индивидуализированный, постоянный надзор и прогнозный анализ, помогая распознавать время и оптимизируя терапевтические методы. В этой рукописи рассматриваютс

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… Cui et al. also reported an AI-assisted colorimetric biosensor for smartphones that detects harmful germs quickly and accurately in a visible manner [ 44 ]. … They have developed a body strap device for glucose sensing, integrated with smartphone applications via Bluetooth. …

Оценка Фондаоскопии в качестве инструмента скрининга для оптической нервы в многоразовом склерозе: компаративное исследование на тему оптической согласованности (OCT).

Фон: Множественный склероз (MS) представляет собой хроническое и иммунопосредованное расстройство центральной нервной системы (CNS), характеризующееся воспалением, обезвоживанием и нейродегенерацией, приводящее к нарушению проводимости аксонового сигнала. Оптический неврит (ОН) встречается более чем 70% :: случаи MS с уделением особого внимания участию зрительного нерва в развитии болезни. Атрофия оптического нерва, дополняющая воспламенительный эпизод, может наблюдаться во время фундоскопии в качестве паллора во временном квадранте или во всем оптическом диске. Наше исследование направлено на

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… Smartphone fundus photography has been proven to be a cheap, portable, effective, and highly available method of evaluating posterior segment elements. … Wintergerst et al. performed a comparative study in order to observe the differences between undilated and dilated smartphone-based FP for optic nerve head evaluation. …