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Study on the cutting technology of chayote (Sechium edule) and the physiological mechanism of rooting regulation by exogenous hormones.

BACKGROUND: 'Tuershao' is a new chayote (Sechium edule) variety whose tuberous roots and tender shoots are edible. These parts are rich in b … O), peroxidase (POD), and superoxide dismutase (SOD) were also enhanced. The contents of endogenous hormones such as auxin (IAA), cytokinin (CTK), and gibberellin A3 (GA3) increased, while abscisic acid (ABA) decreased. CONCLUSIONS: Treating semi-hard branches with 1.0 g·L⁻¹ IBA on peat soil shows the best effect in promoting rooting of 'Tuershao' cutting …

Quantitative Analysis of Selected Circulating Hematological Biomarkers, Essential Minerals, Vitamins, and Thyroid Hormones in Females Affected by Hair Loss.

PURPOSE: To assess the association between hair loss in females and various biomarkers including hemoglobin, iron, ferritin, zinc, selenium, calcium, vitamin D, vitamin B12, folic acid, and thyroid hormones. PATIENTS AND METHODS: This study enrolled 100 women presenting with hair loss and 100 age-matched healthy controls. Venous blood samples were collected for analysis of hematological, hormonal and biochemical parameters. RESULTS: The mean age of participants was comparable between groups (43.06 ± 10.76 vs. 41.39 ± 7.94 years; p = 0.88). Hair loss in females had significantly lower mean le…

The role of sex hormones in the intestinal injury after brain death using a surgical menopause model in rats.

Among transplantable organs, the intestine is one of the most challenging organs to transplant. While there is considerable research on the effects of brain death (BD), little is known about the specific intestinal changes that occur, particularly in females. Here we investigated the role of female sex hormones in the BD-induced intestinal inflammation, using an ovariectomy (OVx) model for sex hormones depletion. Wistar rats (female) were divided into four experimental groups: Control non-OVx - non-manipulated; Control-OVx -ovariectomized; BD non-OVx - animals submitted to BD (6h); BD-OVx -ova…

Effects of rebamipide quadruple therapy with gastrointestinal endoscopy adjuvant therapy on gastrointestinal hormones in patients with gastric ulcer bleeding.

BACKGROUND AND STUDY AIMS: The study aimed to investigate the effect of rebamipide quadruple therapy combined with gastrointestinal endoscopy on gastrointestinal hormones in patients with gastric ulcer bleeding. PATIENTS AND METHODS: A total of 120 patients with gastric ulcer bleeding were enrolled and randomly assigned into a control group and an observation group, with 60 cases in each group. The control group received rebamipide quadruple therapy, while the observation group received gastrointestinal endoscopy combined with rebamipide therapy. The two groups were compared on general data, …

Evaluation of acute and chronic phases of COVID-19 on semen parameters and gonad hormones: A case-control study.

BACKGROUND: Since the outbreak of coronavirus disease 2019 (COVID-19), many studies have provided evidence supporting the adverse effects of … udy evaluated semen parameters, SARS-CoV-2 ribonucleic acid, oxidative stress (OS) markers, and sex hormones. RESULTS: The study revealed significant differences in semen parameters consisting of motility (p < 0.001), progressive motility (p < 0.001), and normal morphology (p = 0.001) between the study groups, as well as within the COVID+ group comparing …

Effects of high and moderate intensity exercise training on sex hormones and testicular damage induced by cisplatin in rats.

BACKGROUND: Cisplatin, a potent chemotherapeutic agent, induces oxidative stress, inflammation, and apoptosis in the testes, reduces sex hormones (testosterone, LH, FSH), and impairs sperm quality and structure. MICT typically increases testicular function and hormone levels, whereas HIIT may negatively affect steroidogenesis and the HPG axis, although findings vary. This study investigates the effects of HIIT and MICT on reducing cisplatin-induced testicular damage in rat, providing a noninvasive approach to preserve fertility for chemotherapy patients. METHODS: In this randomized controlled …

Efficacy of levocarnitine combined with tadalafil in treating oligozoospermia and asthenozoospermia: effects on serum sex hormones and sexual function.

OBJECTIVE: This study aimed to evaluate the efficacy of combining levocarnitine with tadalafil in treating oligozoospermia and asthenozoospe … d levocarnitine alone. Both groups continued the regimen for 3 months. Parameters such as serum sex hormones [testosterone (T), luteinizing hormone (LH), follicle-stimulating hormone (FSH)], sexual function [assessed via the International Index of Erectile Function (IIEF)], and semen quality [including semen volume, sperm concentration, sperm viability, an …

Effects of Subanesthetic Intravenous Ketamine Infusion on Stress Hormones and Synaptic Density in Rats with Mild Closed-Head Injury.

Background: Every year, over 40 million people sustain mild traumatic brain injury (mTBI) which affects the glucocorticoid stress pathway and synaptic plasticity. Ketamine, a multimodal dissociative anesthetic, modulates the stress pathway and synaptic plasticity. However, the effects of post-mTBI ketamine administration on plasma stress hormones and brain synaptic plasticity are largely unknown. Methods: Adult male Sprague-Dawley rats with indwelling jugular venous catheters sustained mTBI with the Closed-Head Impact Model of Engineered Rotational Acceleration (CHIMERA) in a single session (3…

In utero exposure to synthetic sex hormones and their multigenerational impact on neurodevelopmental disorders: Endocrine disruptors as neuroendocrine disruptors.

BACKGROUND: Synthetic sex hormones, estrogens and/or progestogens, have been widely administered without sufficient long-term studies for decades to millions of pregnant women around the world and although most were banned in the 1970s and 1980s, some progestins continue to be prescribed. Psychiatric disorders, including psychoses such as schizophrenia, bipolar disorders, or severe depression, anxiety, eating disorders, as well as ASD (autism spectrum disorders), accompanied or not by co-morbidities, have been described in children exposed in utero. AIM: In this review, we have gathered the m…

Effects of Pre-Conception Stress and Dracocephalum moldavica Extract on Sperm Parameters and Sex Hormones in Parents and Offspring.

BACKGROUND: Stress is one of the causes of fertility weakness in both females and males and herbal approaches may reduce this harmful effect. This study aimed to investigate the effect of Dracocephalum moldavica (DM) on the reproductive system in parental pre-pregnancy stress. MATERIAL AND METHODS: In this experimental study, male and female rats were divided into four groups as follows: control, stress (restraint stress daily for 50 and 15 days for male and female, respectively), extract, and stress + extract. After treatment, the control and experimental rats were mated. Pregnant females we

The relationship between thyroid hormones sensitivity and hyperhomocysteinemia: a cross-sectional study based on Chinese health check-up population.

BACKGROUND: It is unclear if impaired thyroid hormone sensitivity interacts with homocysteine (Hcy), a known risk factor for cardiovascular diseases (CVD), despite the fact that it has been identified as a prevalent metabolic condition.We aimed to analyze the association between thyroid hormone sensitivity indices and homocysteine levels in a Chinese health check-up population. METHODS: Thyroid hormone sensitivity was assessed by the Thyroid Feedback Quantization Index (TFQI), the parameter TFQI (PTFQI), the TSH index (TSHI) and the thyrotropin thyroxine resistance index (TT4RI) and FT3/FT4 r

A questionnaire survey of thyroid specialists in Japan on the use of thyroid hormones in hypothyroid and euthyroid patients.

Levothyroxine (LT4) is the established treatment for hypothyroidism but some controversies, such as whether combining it with liothyronine ( … were considered as the main contributors to residual symptoms. Respondents would prescribe thyroid hormones in euthyroid subjects for female infertility with positive anti-thyroid antibodies (46.9%), for Hashimoto's disease with a huge goiter (29.0%), and for pregnant or infertile women with TSH between 2.5-4 mU/L irrespective of anti-thyroid antibody sta …

Воздействие сексуальных гормонов на транскраниальную магнитную стимуляцию против окисляющего стресса в патогенезе множественного склероза.

Множественный склероз (MS) — аутоиммунное нейродегенеративное заболевание с более высоким уровнем заболеваемости среди женщин. Несмотря на то, что половое созревание, по всей видимости, является одним из факторов, лежащих в основе НР, менопауза не оказывает четкого воздействия на прогрессию заболеваний. Многие исследования показали, что транскраниальная магнитная стимуляция (TMS) является потенциальной антиоксидантной терапией для MS, однако сексуальные гормоны были определены как потенциальный фактор, влияющий на реакцию TMS путем воздействия на корковую фортификацию и, возможно, клинические

Совпадение в аннотации оригинала
BACKGROUND: Multiple sclerosis (MS) is an autoimmune neurodegenerative disease with a higher prevalence in women. While puberty appears to act as a trigger for MS, menopause has no clear effects on disease progression. Many studies have shown that transcranial magnetic stimulation (TMS) is a potential antioxidant treatment for MS, but the sexual hormones hav…

Impact of benzo[a]pyrene, PCB153 and sex hormones on human ESC-Derived thyroid follicles using single cell transcriptomics.

INTRODUCTION: Endocrine disruptors are compounds of manmade origin able to interfere with the endocrine system and constitute an important environmental concern. Indeed, detrimental effects on thyroid physiology and functioning have been described. Differences exist in the susceptibility of human sexes to the incidence of thyroid disorders, like autoimmune diseases or cancer. METHODS: To study how different hormonal environments impact the thyroid response to endocrine disruptors, we exposed human embryonic stem cell-derived thyroid organoids to physiological concentrations of sex hormones re…

Lifetime chronic stress exposures, stress hormones, and biological aging: Results from the Midlife in the United States (MIDUS) study.

Psychosocial stress and adversity have been linked to accelerated aging and increased risk for age-related diseases. Animal and in vitro studies have shown that exposure to stress hormones (catecholamines, glucocorticoids) can impact biological aging processes such as DNA damage and cellular senescence, suggesting they play a key role in links between stress and aging; however, these associations have not been well investigated in humans. We examined cross-sectional associations between chronic stress exposures, stress hormones, and biological aging markers in midlife adults and whether stress…

Differential changes in appetite hormones post-prandially based on menstrual cycle phase and oral contraceptive use: A preliminary study.

This was a preliminary study that examined whether appetite regulation is altered during the menstrual cycle or with oral contraceptives. Ten naturally cycling females (NON-USERS) and nine tri-phasic oral contraceptive using females (USERS) completed experimental sessions during each menstrual phase (follicular phase: FP; ovulatory phase: OP; luteal phase: LP). Appetite perceptions and blood samples were obtained fasted, 30, 60, and 90 min post-prandial to measure acylated ghrelin, active glucagon-like peptide-1 (GLP-1), and total peptide tyrosine tyrosine (PYY). Changes were considered import

Transgenerational epigenetic self-memory of Dio3 dosage is associated with Meg3 methylation and altered growth trajectories and neonatal hormones.

Intergenerational and transgenerational epigenetic effects resulting from conditions in previous generations can contribute to environmental adaptation as well as disease susceptibility. Previous studies in rodent and human models have shown that abnormal developmental exposure to thyroid hormone affects endocrine function and thyroid hormone sensitivity in later generations. Since the imprinted type 3 deiodinase gene (Dio3) regulates sensitivity to thyroid hormones, we hypothesize its epigenetic regulation is altered in descendants of thyroid hormone overexposed individuals. Using DIO3-defici…

An orthogonal approach for analysis of underivatized steroid hormones using ultrahigh performance supercritical fluid chromatography-mass spectrometry (UHPSFC-MS).

The crucial role of steroid hormones in health and diseases merits their high-throughput, accurate and affordable measurements in biological specimens. Despite advances in analytical methods, sensing and quantifying steroid hormones remains challenging. Immunoassays offer excellent sensitivity but are inherently labour-intensive, costly, and prone to false positives. Mass spectrometry (MS) has been increasingly utilised, with the main hurdle being the isobaric tendencies of similar analytes, which complicates their separation and accurate quantification. This study compares ultrahigh-performan…

Occurrence and distribution of steroid hormones (estrogen) and other contaminants of emerging concern in a south indian water body.

Steroid hormones (SHs) are among the important classes of Contaminants of Emerging Concern (CECs) whose detection in aquatic environments is vital due to their potential adverse health impacts. Their detection is challenging because of their lower stability in natural conditions and low concentrations. This study reports the presence of steroid hormones in a major river system, the Periyar River, in Kerala (India). Water samples were collected from thirty different river locations in the case of SHs and five locations within these in the case of other CECs. These were subjected to LC-MS/MS and…

Associations between serum per- and polyfluoroalkyl substances and thyroid hormones in Chinese adults: A nationally representative cross-sectional study.

Disruption of thyroid homeostasis has been indicated in human studies on the effects of per- and polyfluoroalkyl substances (PFASs). However, limited research exists on this topic within the general Chinese population. Based on a substantial and representative sample of the Chinese adult population, our study provides insight into how PFASs specifically affect thyroid homeostasis. The study included 10 853 participants, aged 18 years and above, sampled from nationally representative data provided by the China National Human Biomonitoring (CNHBM). Weighted multiple linear regression and restric