Результаты поиска

Tooth agenesis association with self-reported family history of cancer.

It has been proposed that tooth agenesis and cancer development share common molecular pathways. We performed a cross-sectional study to investigate the epidemiological and molecular association between tooth agenesis and self-reported family history of cancer. Eighty-two individuals with tooth agenesis and 328 individuals with no birth defect were recruited from the same institution. Tooth agenesis was assessed in permanent teeth and was defined based on the age of the participants and when initial tooth formation should be radiographically visible. We also investigated the role of genes invo

Factors affecting long-term survival after aortic valve replacement.

BACKGROUND AND AIM: To evaluate long-term outcomes of surgical aortic valve replacement (AVR) due to significant aortic stenosis (AS) and assess changes in factors affecting survival during a 10-year period in patients referred for surgery from a single centre. METHODS: We evaluated 1143 patients (478 women, 665 men; mean age 61 ± 5 years) treated in the Department of Valvular Heart Disease at the Institute of Cardiology in Warsaw who were referred for AVR due to significant AS in 1998-2008 and survived the surgery and the initial 30-day postoperative period. We assessed long-term survival in

Connective tissue graft and resin glass ionomer for the treatment of gingival recession associated with noncarious cervical lesions: a case series.

This article describes the treatment of gingival recession associated with noncarious cervical lesions by a connective tissue graft in combination with a resin-modified glass-ionomer restoration (CTG + R). Eleven patients showing the association of recession and lesions were selected and treated by CTG + R. Bleeding on probing, probing depth, relative gingival recession, clinical attachment level, noncarious cervical lesion height, and dentin sensitivity were measured. The treatment provided statistically significant gains in clinical attachment level and shallow probing depths. The percentage

Fracture resistance of immature teeth filled with BioAggregate, mineral trioxide aggregate and calcium hydroxide.

UNLABELLED: Abstract -  Background: The aim of this in vitro study was to assess the long-term fracture resistance of human immature permanent teeth filled with BioAggregate (BA), mineral trioxide aggregate (MTA) and calcium hydroxide (CH). MATERIALS AND METHODS: The study consisted of single rooted premolar teeth with immature root formation extracted for orthodontic reasons. A total of 28 immature premolars with average root length of 10.7 mm and apical diameter of 3 mm were included in the study. The pulps were extirpated and the canals were prepared using an apical approach. The teeth wer

Effectiveness of a lower lingual arch as a space holding device.

The aims of this study were to evaluate the effectiveness of a lower lingual holding arch (LLHA) in maintaining arch length, and to compare the effectiveness of two LLHAs made of two different gauges (0.9 and 1.25 mm) of stainless steel (SS) wire. The sample comprised 44 subjects (24 males and 20 females) who for various reasons attended orthodontic clinics at Jordan University of Science and Technology Dental Teaching Center. The subjects were randomly divided into two treatment groups. The first group contained 20 subjects (12 males/8 females, average age 10.76 ± 0.75 years). The LLHA used i

Three-year clinical evaluation of cuspal coverage with combined composite-amalgam in endodontically-treated maxillary premolars.

This clinical study evaluated the clinical performance of cuspal coverage with combined composite-amalgam restorations in endodontically-treated maxillary premolars over a three-year period. Thirty-six maxillary premolars, each with a Class II cavity in 36 patients ranging in age between 28 and 52 years, were selected after endodontic treatment. After reduction of the buccal and palatal cusps, internal coverage and veneering of the reduced buccal cusp was performed with composite. The remaining cavity and reduced palatal cusp were restored with high-copper amalgam. The restorations were evalua

Treatment outcomes of ligature-induced recession in the dog model using guided tissue regeneration or coronally positioned flap procedures.

AIM: The aims of the study were: (1) to determine the quality of the hard and soft tissues formed in segments treated with coronally positioned flaps alone (CPF group) or combined with a polylactic acid resorbable membrane (guided tissue regeneration--GTR group) in wide type defects (canine teeth), and (2) to evaluate the behaviour of the newly regenerated tissues to an experimentally induced inflammation initiated by microbial plaque at the submarginal level in recession type defects (premolar teeth). MATERIALS AND METHODS: The randomized block design was used in the study, with each dog rec

Prevalence of third molar impaction in orthodontic patients treated nonextraction and with extraction of 4 premolars.

The purposes of this study were to confirm that premolar extraction treatment is associated with mesial movement of the molars concomitant with an increase in the eruption space for the third molars and to test the hypothesis that such treatment reduces the frequency of third molar impaction. Lateral cephalograms, panoramic or periapical radiographs, and study models made before (T1) and after (T2) treatment and a minimum of 10 years postretention (T3) of 157 patients were selected from the postretention sample at the Department of Orthodontics of the University of Washington, Seattle. Treatme

A radiographic comparison of apical root resorption after orthodontic treatment with a standard edgewise and a straight-wire edgewise technique.

The purpose of this study was to compare the severity of apical root resorption occurring in patients treated with a standard edgewise and a straight-wire edgewise technique, and to assess the influence of known risk factors on root resorption incident to orthodontic treatment. The sample consisted of 80 patients with Angle Class II division 1 malocclusions, treated with extraction of at least two maxillary first premolars. Variables recorded for each patient included gender, age, ANB angle, overjet, overbite, trauma, habits, invagination, agenesis, tooth shedding, treatment duration, use of C

Preventing cardiac diseases in childhood.

OBJECTIVE: The burden of cardiac disease in childhood is unknown. It will be a sum of 1% of living births in the general population, suffering from Congenital Heart Disease (CHD) + approximately 2.5% of the general population suffering from bicuspid aortic valve diseases + an unknown higher prevalence of acquired diseases. Cardiomyopathies, arrhythmias - sudden cardiac death (SCD), rheumatic heard disease, hypertension and accelerating atherosclerosis are among the most frequent. Adding on, genetic syndromes including cardiac defects, endocarditis and myocarditis we can address a large pediatr…

[Congenital heart defects in Iceland 1990-1999.].

OBJECTIVE: About 1% of live born children have congenital heart defects (CHD). Knowledge of the true incidence of CHD is important because o … l septal defect (ASD) smaller than four millimeters were excluded. We also studied the incidence of bicuspid aortic valve (BAV). All diagnoses were confirmed with echocardiography and in some cases cardiac catheterization. RESULTS: Between 1990 and 1999 there were 44,013 live births in Iceland, 740 children were diagnosed with a CHD or 1.7% of live born c …

Valve repair after infective endocarditis secondary to perforation caused by Streptococcus gordonii: A case report.

BackgroundWe report a case of infective endocarditis (IE) in a patient with congenital heart valve lesions accompanied by IE, which was diagnosed based on blood culture analysis that revealed the presence of a gram-negative bacterium, Streptococcus gordonii.Case summaryThe patient had a history of precordial valve disease diagnosed by cardiac ultrasound, as well as a 4-mo history of fever. He was subjected to comprehensive anti-infection and anti-heart failure treatment in the internal medicine department. Further examination revealed sudden dislodgement from and perforation through the aortic

Совпадение в полном тексте источника
… The intraoperative examination findings were as follows: Moderate levels of yellowish pericardial fluid were present, there was marked widening of the ascending aorta, marked malformation of the aortic bicuspid valve, leaflet destruction with perforation and massive regurgitation, complete leaflet removal …

Secreted Klotho Attenuates Inflammation-Associated Aortic Valve Fibrosis in Senescence-Accelerated Mice P1.

Senescence-accelerated mice P1 (SAMP1) is an aging model characterized by shortened lifespan and early signs of senescence. Klotho is an aging-suppressor gene. The purpose of this study is to investigate whether in vivo expression of secreted klotho (Skl) gene attenuates aortic valve fibrosis in SAMP1 mice. SAMP1 mice and age-matched (AKR/J) control mice were used. SAMP1 mice developed obvious fibrosis in aortic valves, namely fibrotic aortic valve disease. Serum level of Skl was decreased drastically in SAMP1 mice. Expression of MCP-1 (monocyte chemoattractant protein 1), ICAM-1 (intercellula

Evaluation of corticotomy-facilitated orthodontics and piezocision in rapid canine retraction.

INTRODUCTION: The purpose of this study was to evaluate the efficiency of corticotomy-facilitated orthodontics and piezocision in rapid canine retraction. METHODS: The sample consisted of 20 patients (15-25 years old) with Class II Division 1 malocclusions. The suggested treatment plan was extraction of the maxillary first premolars with subsequent canine retraction. The sample was divided into 2 equal groups. In the first group, 1 side of the maxillary arch was randomly chosen for treatment with corticotomy, and in the second group, piezocision treatment was used. The contralateral sides of

Exploring Regulatory Mechanisms of Atrial Myocyte Hypertrophy of Mitral Regurgitation through Gene Expression Profiling Analysis: Role of NFAT in Cardiac Hypertrophy.

BACKGROUND: Left atrial enlargement in mitral regurgitation (MR) predicts a poor prognosis. The regulatory mechanisms of atrial myocyte hypertrophy of MR patients remain unknown. METHODS AND RESULTS: This study comprised 14 patients with MR, 7 patients with aortic valve disease (AVD), and 6 purchased samples from normal subjects (NC). We used microarrays, enrichment analysis and quantitative RT-PCR to study the gene expression profiles in the left atria. Microarray results showed that 112 genes were differentially up-regulated and 132 genes were differentially down-regulated in the left atria

Quadruple valve replacement and bypass surgery 23 years after the Ross operation†.

This report describes a case of simultaneous quadruple valve replacement, coronary artery bypass surgery and reconstruction of one aortic sinus performed in a patient who had undergone the Ross operation 23 years previously.

Connective tissue graft associated or not with low laser therapy to treat gingival recession: randomized clinical trial.

BACKGROUND: To evaluate the treatment of gingival recession with a connective tissue graft (CTG) alone or in combination with low-level laser therapy (CTG + L). METHODS: Forty patients presenting 40 Miller Class I and II gingival recessions were included. The defects were randomly assigned to receive either CTG (n = 20) or CTG + L (n = 20). A diode laser (660 nm) was applied to the test sites immediately after surgery and every other day for 7 days (eight applications). RESULTS: The mean percentage of root coverage was 91.9% for the test group and 89.48% for the control group after 6 months

Brånemark system implants and rare disorders: a report of six cases.

Rare disorders are conditions defined as either fatal or causing chronic functional impairment. There is limited evidence of the behavior of oral implants in patients suffering from such diseases, and the existing data are merely based on cases reports. This paper describes the outcome of implant treatment after up to 15 years of function in three patients afflicted with X-linked hypophosphatemia, two patients with Langerhans cell histiocytosis, and one patient with osteogenesis/dentinogenesis imperfecta.

Buccal plate preservation with immediate post-extraction implant placement and provisionalization: preliminary results of a new technique.

Bone resorption and remodelling are inevitable sequelae of dental extraction and begin immediately after the extraction procedure. The buccal plate is especially predisposed to these phenomena, and if affected, may result in an increased risk of facial soft-tissue recession and other adverse clinical effects that may decrease the predictability of implant placement or impair the final aesthetic result. Buccal plate preservation is a new technique aimed at maintaining or improving the appearance of the soft and hard tissues after dental extraction procedures. The aim of this case series is to e