Результаты поиска

Silver-impregnated, antibiotic-impregnated or non-impregnated ventriculoperitoneal shunts to prevent shunt infection: the BASICS three-arm RCT.

BACKGROUND: Insertion of a ventriculoperitoneal shunt to treat hydrocephalus is one of the most common neurosurgical procedures worldwide. Shunt infection affects up to 15% of patients, resulting in long hospital stays, multiple surgeries and reduced cognition and quality of life. OBJECTIVES: The aim of this trial was to determine whether or not antibiotic-impregnated ventriculoperitoneal shunts (hereafter referred to as antibiotic shunts) (e.g. impregnated with rifampicin and clindamycin) or silver-impregnated ventriculoperitoneal shunts (hereafter referred to as silver shunts) reduce infect

A Transferable Evaluation Framework for Mobile Health Data Collection in Shift-Work Nurses: Development and Feasibility Study.

BACKGROUND: Shift-work nurses experience substantial variability in work schedules, health behaviors, and recovery patterns, which traditional retrospective surveys fail to capture due to recall bias. Although mobile health (mHealth) tools offer ecological momentary data capture, existing off-the-shelf survey platforms lack shift-synchronized notification logic and impose excessive cognitive friction on fatigued clinicians, limiting their applicability in nursing research. OBJECTIVE: This study aimed to propose and demonstrate a transferable, dual-perspective evaluation framework for mHealth

A comparative analysis of dental education in China and Japan based on the four-component instructional design (4C/ID) model.

BACKGROUND: Balancing cognitive load and clinical psychomotor skills within a limited curriculum time remains a core challenge in dental education. Faced with new healthcare demands driven by an aging population, dental education systems in both China and Japan require essential reforms. While current cross-national comparative studies mainly focus on macro-policy levels, introducing an objective educational model helps systematically analyze the core logical differences in micro-level pedagogical implementation and cognitive load management strategies. This study aims to examine differences i

The role of discharge planning services in continuity of care for patients with diabetes: a scoping review.

BACKGROUND: Diabetes has become a major global public health challenge. Increasing pressure on healthcare systems and shorter hospital stays highlight the importance of effective discharge planning in enhancing post-discharge self-management and continuity of care for people with diabetes. AIM: This scoping review aimed to map existing discharge planning practices that support continuity of care for people with diabetes and to inform the optimization of intervention programs in clinical practice. METHODS: The review was conducted according to the Joanna Briggs Institute (JBI) methodology and

Sleep Irregularity is Associated with Reduced Wellbeing in Patients with Cirrhosis.

BACKGROUND AND AIMS: Health-related quality of life (HRQoL) is frequently impaired in cirrhosis. Among the most critical components of reduced HRQoL in cirrhosis is disturbed sleep. Despite the importance of sleep in cirrhosis and overall health, sleep is rarely clinically assessed and the specific aspects of sleep which drive reduced wellbeing are understudied. Remote monitoring with wearable technology may facilitate sleep assessment and targeted intervention. METHODS: We enrolled 119 participants with cirrhosis across two academic medical centers and collected baseline clinical, cognitive

beta Testing a Medical Symptom Management для людей с продвинутым раком: Исследование одноразовой осуществимости и приемлемости.

КОЛИЧЕСТВО: Люди, страдающие раком, имеют более частые и серьезные симптомы, чем лица, страдающие ранней стадией заболевания. Обычные, тревожные симптомы включают трудности со сном, беспокойство и неуверенность, усталость и депрессию. Когнитивная поведенческая терапия (КБТ) и терапия принятия и принятия обязательств (АКТ) эффективно устраняют эти симптомы, но зачастую они являются слишком продолжительными для пациентов с несколькими назначениями, ограниченной энергией и конкурирующими приоритетами. Кратко говоря, мобильные медицинские услуги (медицинское обслуживание) являются доступной альтер

Совпадение в полном тексте источника
… Marthick M McGregor D Alison J Cheema B Dhillon H Shaw T Supportive care interventions for people with cancer assisted by digital technology: systematic review J Med Internet Res Oct 29 2021 23 10 e24722 doi 10.2196/24722 Medline 34714246 PMC8590193 20. …

A Gamified mHealth App to Promote Physical Activity and Reduce Sedentary Behavior in Autistic Adults: Protocol for a Remotely Delivered Pilot Intervention Study.

BACKGROUND: Research indicates that many autistic adults are insufficiently active and overly sedentary. There is limited evidence on effective strategies to increase physical activity (PA) and reduce sedentary behavior (SB) in this population. Gamified mobile health (mHealth) interventions show promise for addressing these challenges by leveraging autistic individuals' strengths in visuospatial learning and their affinity for digital gaming. Despite this potential, it remains unclear how well these interventions translate to real-world settings. This gap is compounded by the lack of community

Evaluating Perceptions of the CANreduce 2.0 eHealth Intervention for Cannabis Use: Focus Group Study.

BACKGROUND: Cannabis is the most widely used illicit drug, and admissions for cannabis use disorders (CUDs) are increasing globally, posing a significant public health challenge. Despite its negative consequences, a substantial proportion of individuals with problematic use do not seek treatment. In recent years, digital health interventions (DHIs) have emerged as accessible and cost-effective solutions, empowering users to manage their health care. CANreduce is one such eHealth intervention that has demonstrated effectiveness in reducing cannabis use (CU); however, its suboptimal adherence ra

Evaluation of internal fixation stability of distal humerus C-type fractures based on musculoskeletal dynamics: finite element analysis under dynamic loading.

PURPOSE: This study establishes a quantitative anatomical-mechanical-clinical decision-making mapping relationship using the Digital Intelligence Orthopaedic Technology, systematically analyses the dynamic biomechanical characteristics of distal humerus fracture in the postoperative period, and establishes the quantitative correlation between optimal strategies of plate configuration and safety thresholds for joint activities, to provide the scientific basis for optimizing internal fixation schemes and quantifying postoperative rehabilitation strategies. METHODS: Upper limb muscle modeling wa

Decreasing Opioid Addiction and Diversion Using Behavioral Economics Applied Through a Digital Engagement Solution: Protocol for a Randomized Controlled Trial.

BACKGROUND: Despite strong and growing interest in ending the ongoing opioid health crisis, there has been limited success in reducing the p … y. RESULTS: This study is being funded and supported by the CLHSS Rapid Prospective Evaluation and Digital Technology Innovation Programs, and M Health Fairview. Support and coordination provided by CLHSS include the structure of engagement, survey development, data collection, statistical analysis, and dissemination. The project was initially started in August 202 …

Association of patient activity bio-profiles with health-related quality of life in patients with newly diagnosed multiple myeloma: a prospective observational cohort study.

BACKGROUND: Due to the nature of their disease, patients with multiple myeloma (MM) often have bone disease-related pain that limits physical activity and diminishes health-related quality of life (HRQOL). Digital health technology with wearables and electronic patient reported outcome (ePRO) tools can provide insights into MM HRQoL. METHODS: In this prospective observational cohort study conducted at Memorial Sloan Kettering Cancer in NY, NY, USA, patients with newly diagnosed MM (n = 40) in two cohorts (Cohort A - patients <65 years; Cohort B - patients ≥65 years) were passively remote-moni

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… Implications of all the available evidence Digital technology solutions may provide unique insight into the cancer patient experience by passively capturing objective data measurements through more detailed comprehensive timepoints. … To capture more user participants and increase compliance of continuous monitoring, further work is needed to explore whether digital technology can be utilized in an “ active ” capacity, where wearables directly increase or influence patient HRQoL through motivation and positive biofeedback algorithms …

Anti-apoptotic protein BCL-XL as a therapeutic vulnerability in gastric cancer.

BACKGROUND: New therapeutic targets are needed to improve the outcomes for gastric cancer (GC) patients with advanced disease. Evasion of programmed cell death (apoptosis) is a hallmark of cancer cells and direct induction of apoptosis by targeting the pro-survival BCL2 family proteins represents a promising therapeutic strategy for cancer treatment. Therefore, understanding the molecular mechanisms underpinning cancer cell survival could provide a molecular basis for potential therapeutic interventions. METHOD: Here we explored the role of BCL2L1 and the encoded anti-apoptotic BCL-XL in GC.

Deep learning for AI-based diagnosis of skin-related neglected tropical diseases: A pilot study.

BACKGROUND: Deep learning, which is a part of a broader concept of artificial intelligence (AI) and/or machine learning has achieved remarkable success in vision tasks. While there is growing interest in the use of this technology in diagnostic support for skin-related neglected tropical diseases (skin NTDs), there have been limited studies in this area and fewer focused on dark skin. In this study, we aimed to develop deep learning based AI models with clinical images we collected for five skin NTDs, namely, Buruli ulcer, leprosy, mycetoma, scabies, and yaws, to understand how diagnostic accu

[Assessment of the quality of life of mandibular ameloblastoma patients after reconstruction with double-barrel fibula flap].

Objective: To analyse the quality of life of patients receiving repair of bone defect with folded fibula flap after removal of mandibular ameloblastoma. Methods: The case data of 39 patients with ameloblastoma admitted to the First Affiliated Hospital of Zhengzhou University from August 2013 to April 2016 were retrospectively analysed, including 21 males and 18 females, from 18 to 58 years old. 3D printing and digital technology were used in flap preparation before surgery in all patients. The folded fibular flaps were used to repair mandibular defects and the implants were placed between 6-9 …

Acceptability of a Mobile Phone Support Tool (Call for Life Uganda) for Promoting Adherence to Antiretroviral Therapy Among Young Adults in a Randomized Controlled Trial: Exploratory Qualitative Study.

BACKGROUND: Adherence to treatment is critical for successful treatment outcomes. Although factors influencing antiretroviral therapy (ART) adherence vary, young adults are less likely to adhere owing to psychosocial issues such as stigma, ART-related side effects, and a lack of access to treatment. The Call for Life Uganda (CFLU) mobile health (mHealth) tool is a mobile phone-based technology that provides text messages or interactive voice response functionalities through a web interface and offers 4 modules of support. OBJECTIVE: This study aims to describe the acceptability and feasibilit

Technical and Psychosocial Challenges of mHealth Usage for Antiretroviral Therapy Adherence Among People Living With HIV in a Resource-Limited Setting: Case Series.

BACKGROUND: Mobile communication has been found to improve antiretroviral therapy (ART) adherence among people living with HIV. In an ongoing randomized clinical trial, 2 mobile communication strategies (ie, sending SMS text messages and real-time medication monitoring [RTMM]) were used to improve adherence to ART among people living with HIV in Tanzania. We noticed remarkable discrepancies between self-reported adherence and adherence recorded by SMS text messaging or RTMM among some of the first trial participants. OBJECTIVE: Our objective was to describe these cases and the observed discre

[Experimental study on the improvement of Ilizarov transverse tibial bone transport and microcirculation reconstruction technique].

Objective: To observe the effect of traditional and modified Ilizarov transverse tibial bone transport on microvascular regeneration of lower limbs in dogs. Methods: After general anesthesia on 10 experimental dogs, traditional and modified transverse tibial bone transport were performed on both tibias respectively. The control group was treated with the traditional method (the periosteum and bone flap were completely isolated), while the experimental group was treated with the modified method (the fibular periosteum of the open window bone flap was retained). All the external fixators were pu

Preliminary Evaluation of a Web-Based Psychological Screening Tool in Adolescents Undergoing Minimally Invasive Pectus Surgery: Single-Center Observational Cohort Study.

BACKGROUND: Preoperative anxiety and depression are predominant risk factors for increased postoperative pain. Thoracic wall deformities in adolescents often cause low self-esteem, which contributes to psychological concerns. Several studies have suggested a relationship between preoperative mental health support and enhanced recovery after surgery. OBJECTIVE: This study investigated the validity of screening questionnaires concerning psychological trait and state characteristics via a patient-specific online platform. METHODS: Patients scheduled for elective pectus surgery between June 2017

Internet-Assisted Parent Training Intervention for Disruptive Behavior in 4-Year-Old Children: A Randomized Clinical Trial.

IMPORTANCE: There is a large gap worldwide in the provision of evidence-based early treatment of children with disruptive behavioral problem … trategy of population-based screening of children at an early age to offering parent training using digital technology and telephone coaching is a promising public health strategy for providing early intervention for a variety of child mental health problems. TRIAL REGISTRATION: clinicaltrials.gov Identifier: NCT01750996.

Safety risks associated with the lack of integration and interfacing of hospital health information technologies: a qualitative study of hospital electronic prescribing systems in England.

BACKGROUND: Substantial sums of money are being invested worldwide in health information technology. Realising benefits and mitigating safety risks is however highly dependent on effective integration of information within systems and/or interfacing to allow information exchange across systems. As part of an English programme of research, we explored the social and technical challenges relating to integration and interfacing experienced by early adopter hospitals of standalone and hospital-wide multimodular integrated electronic prescribing (ePrescribing) systems. METHODS: We collected longit