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Recurrent fungal iris granuloma in a 10-year-old child.

PURPOSE: To report the diagnosis of a case of recurrent iris fungal granuloma presumed to be an iris tuberculoma in a 10-year-old girl. DESIGN: Case report METHODS: Retrospective medical chart review including serological and microbiological investigative results RESULTS: A patient presented with iris mass associated with anterior uveitis. Serological tests were positive for IgM of tuberculosis. Steroids treatment was initiated in conjunction with anti-tuberculosis treatment. The course showed remissions and exacerbation. Fine needle aspiration biopsy (FNAB) of the granuloma proved the etio…

Unusual toxoplasmic chorioretinitis in advanced age: a diagnostic problem.

PURPOSE: To raise awareness regarding presentation of toxoplasmic chorioretinitis late in life, and to discuss the invasive diagnostic optio … retinitis. Acquired ocular toxoplasmosis may be under-recognized as a cause of infectious posterior uveitis and caution should be applied when administering steroids without a definite diagnosis.

[The multidisciplinary practice guideline "The responsible use of biologicals"].

A multidisciplinary working group has developed a practice guideline containing various recommendations on the responsible and efficient use … tic arthritis, juvenile idiopathic arthritis (JIA), psoriasis, ulcerative colitis, Crohn's disease, uveitis and sarcoidosis. This article summarises the most important recommendations contained in the practice guideline. The practice guideline is intended for members of the medical profession in addition to patients, who are considering, or are already, u …

Хориоретинит у младенцев.

ЦЕЛЬ: Цель настоящего обзора заключается в том, чтобы представить информацию о случаях хориоретинита у младенцев, вызванных вирусными и паразитарными инфекциями. МАТЕРИАЛЫ И МЕТОДЫ: В ходе обычного офтальмологического обследования были выявлены четыре ребенка с вирусным хориоретинитом. Были проведены лабораторные тесты на бактериальные, вирусные и паразитарные заболевания. Результаты: Токсоплазмоз, краснуха и инфекция CMV были диагностированы в ходе клинических и лабораторных тестов. После широкого спектра терапии была отмечена полная реанимация подстрекательского процесса во всех обсуждавшихс

Совпадение в аннотации оригинала
PURPOSE: The aim of this review is to present cases of chorioretinitis in infants caused by viral and parasitic infections. MATERIAL AND ME … mission of inflammatory process in all the discussed children was observed. CONCLUSIONS: Posterior uveitis is an ocular complication which can be connected with viral or parasitic infections in postnatal period. Prematurity, normal delivery, intrauterine transmission, breast feeding, comorbid diseases might be associated with chorioretinitis in infants.

[Clinical and radiological features and clinical course of orbital myositis].

Orbital myositis is idiopathic inflammation of the extraocular muscles in the absence of thyroid orbitopathy and often is included under bro … uscle CT scan; absence of clinical and biological thyroid dysfunction: absence of signs of anterior uveitis or scleritis or visual decrease; rapid response to immunomodulator treatment.

An Unusual Case of Motor and Vocal Tics With Obsessive-Compulsive Symptoms in a Young Adult With Behcet's Syndrome.

Behcet's disease is a chronic relapsing-remitting, multi-system inflammatory disorder of unknown etiology, characterized by recurrent oral and genital ulcers, uveitis, and skin lesions. The most common central nervous system findings are demyelization and perivascular cell infiltration; meningoencephalitis, cerebral atrophy, and vascular thrombosis may also occur. Neuropsychiatric symptoms may include: paroxysmal dystonia, parkinsonism, delirium, hallucinations, and behavioral disturbances. We report an unusual case of explosive onset of motor and vocal tics with obsessive-compulsive symptoms …

An ocular cat-scratch disease patient positive for cytoplasmic anti-neutrophil cytoplasmic antibody.

BACKGROUND: We report a case of ocular cat-scratch disease with permanent vision reduction in a patient who was cytoplasmic anti-neutrophil cytoplasmic antibody (C-ANCA) positive. METHODS: Case report and review of the literature. RESULTS: While taking steroids and antibiotics, a 52-year-old man with uveitis associated with cat-scratch disease developed retinal vein occlusion and a macular exudate. His final visual acuity was poor because of residual macular degeneration and optic atrophy. Serum C-ANCA increased and decreased in parallel with ocular inflammatory activity. CONCLUSION: C-ANCA…

Drug therapy in Behçet's disease.

Behçet's disease is one of the most difficult forms of uveitis to treat. Variety in disease presentation and severity, as well as regional differences in standard of care, demand a tailor-made approach. Anterior segment inflammation generally responds to topical corticosteroids. However, the onset of posterior segment inflammation usually requires the advancement of treatment to periocular injections and/or oral administration of corticosteroids. Cyclosporin, either alone or in combination with corticosteroids, is considered in refractory patients. Other immunosuppressive drugs, such as azathi…

Therapeutic applications of antiflammin peptides in experimental ocular inflammation.

Antiflammins are synthetic peptides derived from the region of highest local similarity between uteroglobulin and lipocortin. These peptides have shown anti-inflammatory activity on carrageenan-induced rat footpad edema. They are potent inhibitors for phospholipase A2 activation both in vitro and in vivo. Previously, we have demonstrated the effectiveness of topical antiflammins in suppressing acute ocular inflammation and allergic response in rodent endotoxin-induced uveitis and murine allergic conjunctivitis. The mechanisms by which antiflammins protect against inflammation and allergy in th…

[Behçet's disease: pediatric features].

There is an increased awareness about the pediatric aspects of Behçet's disease (BD) in the world literature. Recent surveys of patients have outlined peculiar features in this age group such as recurrent attacks of fever and abdominal pain. Considered to be uncommon in childhood, uveitis have a very severe course. The higher frequency of familial cases and the genetic anticipation suggest that the genetic component plays a major role in the early expression of the disease. Pediatric aspects of BD including different categories of patients, are not definitely characterized. Indeed it is now ne…

Ocular manifestations of systemic infections.

Ocular involvement, mainly uveitis or retinochoroiditis, is common in various systemic diseases, such as endogenous endophthalmitis, Lyme disease, human T-cell lymphotropic virus type I infection, toxoplasmosis, and toxocariasis. Recent progress, especially in laboratory microbiologic testing, has enabled us to reliably diagnose many formerly idiopathic intraocular inflammatory diseases. A group of systemic infectious diseases, including those discussed here, are implicated as a body of emerging or re-emerging diseases that have appeared in the past two decades and are thought to have a close …

Cricoarytenoid arthritis as an early sign of juvenile chronic arthritis.

A 14-month-old girl developed chronic stridor and dyspnoea. Four months later she presented arthritis, anterior uveitis and positive ANA. Juvenile chronic arthritis (JCA) was diagnosed. Laryngoscopy demonstrated the presence of cricoarytenoid arthritis (CA). The left vocal cord was adducted and immobile, while the right vocal cord had decreased mobility. Erythema and swelling of the arytenoid cartilage on both sides was seen. Steroid treatment resulted in the resolution of these symptoms and made airway control unnecessary. This case demonstrates that CA may be the first sign of JCA, preceding…

Behçet's disease.

The International Study Group's diagnostic criteria for Behçet's disease are gaining acceptance and may be further refined before the decade … rsuit of a better disease marker. The choice of immunosuppressive therapy in severe disease such as uveitis and arteritis is between alkylating agents and agents that inhibit interleukin-2 production.

Fuchs' heterochromic iridocyclitis is not associated with ocular toxoplasmosis.

To analyze the association between Fuchs' heterochromic iridocyclitis (FHI) and toxoplasmosis, we performed ocular examinations and used various specific laboratory tests to establish a role for Toxoplasma gondii in the pathogenesis of FHI. Results were compared with those for other types of uveitis and healthy controls. Of the 88 patients with FHI, nine (10.2%) had toxoplasmosislike scars, but an association could not be proved by the indirect immunofluorescence antibody test or enzyme-linked immunosorbent assay, or by a test for cellular immunity to Toxoplasma antigen. Analysis of aqueous hu…

[Results of vitrectomy in children].

Presented are the results of vitrectomy in children operated in the Ophthalmological Department of Children Health Centre. The procedure was preformed in 110 eyes including 32 vitrectomies and 78 vitrectomies connected with lensectomy. Operated were eyes with chronical uveitis of various etiology, with posttraumatic changes, after vitreal haemorrhages in Eales' disease, in persistent vitreal artery cases. Improvement of the visual acuity was achieved in 68 cases (61.8 p.c.), deterioration was observed in 28 (25.5 p.c.); the visual acuity did not change in 14 cases (12.7 p.c.). Retinal detachme…

Ocular Lyme borreliosis.

In six patients with ocular Lyme borreliosis, bilateral granulomatous iridocyclitis and vitritis were present in five. One of these five also had bilateral optic neuritis. Another patient developed combined trochlear and facial nerve palsies. A syndrome resembling pars planitis with atypical features such as granulomatous keratic precipitates and posterior synechiae should prompt a search for Lyme borreliosis. Topical corticosteroid therapy is necessary to prevent complications of anterior segment inflammation caused by Lyme uveitis, but the benefit of systemic and periocular corticosteroids i…

Successful treatment of metastatic endophthalmitis. Case reports.

Endophthalmitis is a well-recognized complication of intraocular surgery, penetrating ocular trauma and systemic infection. Metastatic bacte … entrations. We report two cases with liver abscess complicated by septic events to the eye. One was uveitis, and the other was endophthalmitis. They were diagnosed early and were successfully treated with parenteral ceftriaxone and good vision was preserved.

Treatment of Behçet's disease with thalidomide.

The clinical response to thalidomide in 30 male patients with Behçet's disease was reviewed. Twenty-six patients with orogenital ulcerations responded (20 completely and 6 partially). Cutaneous lesions including erythema nodosum or necrotic pseudofolliculitis were controlled by treatment in the majority of cases. All patients with arthritis responded (13 completely and 1 partially). Uveitis was improved in 3 patients, stabilizated in 4 and aggravated in 4. Patients with thalidomide purposely discontinued experienced a flare; the reintroduction of therapy controlled the flare. Side effects were…

Juvenile ankylosing spondylitis and HLA B27 homozygosity.

Ten consecutive patients with juvenile ankylosing spondylitis were investigated in a prospective study. At least one of the parents of each patient had a positive history of probable or definite ankylosing spondylitis, Reiter's syndrome, or acute anterior uveitis. The patients and their parents were examined clinically and were HLA-typed. Nine of the 10 patients exhibited the genetic marker HLA B27, but only one patient was homozygous for HLA B27. This prevalence of homozygosity among HLA B27 positive persons could be expected to occur by chance alone. Based on the limited material studied, we…

Pseudoptosis due to acute dacryoadenitis: An unusual presentation of Epstein-Barr virus infection in a child.

Epstein-Barr virus (EBV), a common human herpesvirus, usually causes a self-limited illness in children, manifested by fever, pharyngitis, and lymphadenopathy. However, patients may have atypical presentations including rare ocular manifestations like uveitis, dacryoadenitis, ptosis, or pseudoptosis. In this report, we describe EBV presenting as pseudoptosis in a previously healthy 7-year-old boy. The child was initially worked up as having possible myasthenia gravis with neurologic and ophthalmologic consultations. Ultimately, he was diagnosed with viral dacryoadenitis due to acute EBV infect…