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Transfusion reactions after whole blood transfusion in Norway, 2021-2024: A report from the Norwegian Hemovigilance program.

BACKGROUND: Whole blood (WB) transfusion for major hemorrhage in Western civilian settings has seen a resurgence over the past two decades. … hese findings indicate that WB transfusion in Norway is safe. However, there are inherent risks for blood transfusion in general and also risks more specific to WB transfusion. These include the presence of red blood cell alloantibodies anti-A and anti-B combined with approximately 250 mL plasma from a single donor. Accurate and timely hemovigilance work is importa …

Elderly Gravida with Bombay Blood Group and Placenta Previa Managed with Autologous Blood Transfusion.

The Bombay blood group is a rare blood type with an incidence of around one in a million. There is no known reported case of an obstetric pa … ood for transfusion, and as the Bombay blood group was unavailable, she was managed with autologous blood transfusion which was performed for the first time in a pregnant lady in our institute. She underwent Cesarean section for placenta previa with transverse lie, and both mother and baby were sent home in good health.

Blood transfusion in preterm infants improves intestinal tissue oxygenation without alteration in blood flow.

BACKGROUND AND OBJECTIVE: The objective of the study was to investigate the splanchnic blood flow velocity and oximetry response to blood transfusion in preterm infants according to postnatal age. MATERIALS AND METHODS: Preterm infants receiving blood transfusion were recruited to three groups: 1-7 (group 1; n = 20), 8-28 (group 2; n = 21) and ≥29 days of life (group 3; n = 18). Superior mesenteric artery (SMA) peak systolic (PSV) and diastolic velocities were measured 30-60 min pre- and post-transfusion using Doppler ultrasound scan. Splanchnic tissue haemoglobin index (sTHI), tissue oxygena…

Neonatal exchange transfusion with heparinised whole blood or citrated composite blood: a prospective study.

Heparinised blood should be kept as an available option for neonatal exchange transfusions.

Changes in peripheral blood CD5 (Bla) B-cell populations and autoantibodies following blood transfusion.

BACKGROUND: CD5 B cells and the natural autoantibodies they produce play a role in antigen presentation, tolerance induction, and maintenanc … d cell antibodies and other changes in the immune system caused by exposure to foreign antigens via blood transfusion.

Perinatal outcome in pregnant women: the impact of blood transfusion.

BACKGROUND: Obstetric hemorrhage is a life-threatening complication of pregnancy. Systematic collection of data on transfusion practice during pregnancy and post-partum period are scarce, as well as data on fetal or neonatal outcomes of women transfused during pregnancy.We examined the prevalence of obstetric hemorrhage and outcome of pregnancies in hospitalized transfused women. MATERIALS AND METHODS: This is a retrospective cohort study collecting clinical and laboratory data of women transfused from 2015 to 2017 in three Italian Tertiary level Obstetrical Departments. Inclusion criteria we

A Contemporary Review of Blood Transfusion in Critically Ill Patients.

Blood transfusion is a common therapeutic intervention in hospitalized patients. There are numerous indications for transfusion, including anemia and coagulopathy with deficiency of single or multiple coagulation components such as platelets or coagulation factors. Nevertheless, the practice of transfusion in critically ill patients has been controversial mainly due to a lack of evidence and the need to consider the appropriate clinical context for transfusion. Further, transfusion carries many risk factors that must be balanced with benefits. Therefore, transfusion practice in ICU patients ha…

Impact of Perioperative Blood Transfusion on Postoperative Outcomes in Neonates.

INTRODUCTION: Neonatal postoperative outcomes may be negatively affected by perioperative red blood cell transfusion (RBCT). This study compared 30-day postoperative outcomes between transfused and non-transfused neonates. METHODS: The National Surgical Quality Improvement Program (NSQIP) Pediatric dataset (2021-2022) was used to analyze the association between RBCT and 30-day morbidity and mortality after neonatal surgery. RBCT was defined as transfusion during or within 72 h after surgery. Propensity score matching compared transfused and non-transfused neonates. Secondary analyses examined

No blood transfusion for my own anaemia-tit for tat?

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… In 30 years of clinical work, I took countless decisions of blood transfusions in critically ill patients suffering from anaemia, I discussed ‘thresholds’ for transfusion with colleagues, and—in general—became increasingly strict in respect of indications over the years. … Blood transfusions may cause harm: allergic reactions, fever, acute immune haemolytic reactions, and blood-borne infections. Although the frequency of these risks has been reduced markedly in recent years, they still exist, and every decision to transfuse should be taken carefully. …

Predicting the need for blood transfusion requirement in postpartum hemorrhage.

OBJECTIVE: We aimed to assess the role of lactate and hemoglobin levels as predictors for the need for blood transfusion in post-partum hemorrhage (PPH). METHODS: A retrospective cohort study of women with PPH in a single university-affiliated tertiary medical center between August 2018 and June 2020. PPH was defined as an estimated excessive blood loss (of more than 500 ml following vaginal delivery and 1000 ml following a cesarean delivery) requiring at least one uterotonic drug and fluid resuscitation. Women were stratified by the need of requiring blood transfusion due to hemorrhage. The …

Warming blood products for transfusion to neonates: In vitro assessments.

BACKGROUND: Blood products may be transfused into neonates at temperatures at or below room temperature. The benefits and risks of warming blood to 37°C are not defined in this population or with the equipment used in neonates. Physiologic warming might enhance product effectiveness or decrease transfusion-associated hypothermia. STUDY DESIGN AND METHODS: We utilized an in vitro model of neonatal transfusions, with a syringe pump, blood tubing, and 24-gauge catheter and compared current practice (cold products) vs an inline blood warmer. Transfusions were performed rapidly (30 minutes) and sl

Twelve autologous blood transfusions in eight cats with haemoperitoneum.

OBJECTIVES: The objectives of this study were to describe the clinical use and outcome of autologous transfusions in cats with intracavitary haemorrhage. METHODS: A retrospective descriptive study was performed. Computerised medical records of a single referral centre were searched for cats receiving an autotransfusion. Medical records were evaluated for underlying disease process, autotransfusion technique, autotransfusion volume, time period over which the autotransfusion was given, packed cell volume (PCV) pre- and post-autotransfusion, percentage rise in PCV, use of other blood products a