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Examining two of the ingredients of Cognitive therapy for adolescent social anxiety disorder: Back-translation from a treatment trial.

BACKGROUND: Cognitive Therapy for Social Anxiety Disorder (CT-SAD) based on the Clark & Wells model is a complex intervention comprised of a series of therapeutic elements. Two of the key ingredients are the self-focused attention and safety behaviour experiment and video feedback. The present study examined the effects of these two therapeutic procedures in adolescents with SAD, as well as common themes of the young people's social fears and negative self-images. METHOD: 35 participants with a diagnosis of SAD completed internet-delivered CT-SAD as part of a randomised controlled trial. We c…

Patient-Reported Factors Influencing Clinical Trial Participation: An In-depth Analysis of Patients With Lupus and Rheumatoid Arthritis.

Systemic lupus erythematosus (SLE), a chronic systemic autoimmune disease, has only three approved therapies, despite a rapidly expanding nu … orks. In terms of disadvantages to trial participation, patients with SLE and RA similarly reported fear of unknown interventions, complications, and side effects; only in the population of patients with SLE were fears of a disease flare and of not qualifying reported. SLE literature had a specific emphasis on factors influencing Black patient particip …

Perspectives and experiences of parents of children with juvenile dermatomyositis: a semi-structured interview study.

BACKGROUND: Juvenile Dermatomyositis (JDM) is a rare, childhood inflammatory disease and its management can be challenging and confronting f … ) of 17 children aged 8 to 21 with JDM participated. Six themes were identified. Rapid crescendo of fear and desperation (alarming deterioration, sudden realisation of seriousness, desperate for a diagnosis ), lost and unsupported in the health system (at the mercy of the medical team, frustrated at the lack of services, neglected priorities, protracte …

Лиминальное пространство между надеждой и горем: феномен неопределенности, испытываемый людьми, живущими с повторно излучающим множественный склероз.

СТРУКТУРА: Люди с хроническим заболеванием, страдающие множественным склерозом, подвергаются различной степени глубокой неопределенности. Неопределенность связана с неблагоприятными психологическими последствиями, такими, как чувство повышенной уязвимости, уклонение от принятия решений, страх, беспокойство, тревожное расстройство и даже депрессия. Исследования в области множественного склероза сосредоточены главным образом на научных, практических и психосоциальных вопросах неопределенности. Для сравнения, экзистенциальная неопределенность была недостаточно изучена, даже несмотря на то, что он

Совпадение в аннотации оригинала
BACKGROUND: People with the chronic disease Multiple Sclerosis are subjected to different degrees of profound uncertainty. Uncertainty has been linked to adverse psychological effects such as feelings of heightened vulnerability, avoidance of decision-making, fear, worry, anxiety disorders, and even depression. Research into Multiple Sclerosis has a predomin…

Сохраняется ли нерешительность в отношении вакцинации SARS-COV-2 среди людей с неврологическими заболеваниями - обследование целевой группы NeuroCOVID-19 Европейской академии неврологии.

ОБСУЖДЕНИЕ ПО 3 предметам в онлайновом режиме было направлено в Европейскую академию неврологии (ЕАН) и задалось вопросом о сохранении скептицизма прививок SARS-COV-2, а также о глубинных мыслях и факторах, ограничивающих использование вакцин среди пациентов с неврологическими заболеваниями. Результаты: Мы получили 616 ответов от 84 стран, главным образом из Европы. По мнению лечащего невролога, пациенты с множественным склерозом (MS), нейромнологическими расстройствами (ND) и хроническими неврологическими инфекциями продолжали иметь высокий уровень скептицизма по отношению к вакцинации SARS-C

Совпадение в аннотации оригинала
BACKGROUND: An online 3-item survey was sent to the European Academy of Neurology (EAN) community and inquired about the persistence of SARS … those with sleep disorders. For all other conditions, perceived distrust ranged between 42 and 52%. Fear of adverse events of vaccination or disease reactivation was perceived by 87% of patients with MS/ND and more than 70% of patients with stroke/vascular neurology, neuromuscular disorders, chronic neurological infections, and peripheral neuropathy. P …

How should coronaphobia Be conceptualized? Evaluating competing models of the COVID-19 Phobia Scale using confirmatory factor analysis.

Coronaphobia represents the fears and phobias attributed to the COVID-19 virus and pandemic. The COVID-19 Phobia Scale, previously validated as a four-factor structure, is a widely used multidimensional measure to assess coronaphobia. The current study scrutinized various competing factor structures of this instrument to identify the optimal psychometric representation of coronaphobia. Adults (N = 412) ranging in age from 19 to 84 years completed the COVID-19 Phobia Scale. Several theoretically plausible factor structures of coronaphobia were tested and compared using confirmatory factor analy…

Arabic version of the SF-Qualiveen: cross-cultural adaptation, translation, and validation of urinary disorder-specific instruments in patients with multiple sclerosis.

BACKGROUND: The Short Form Qualiveen (SF-Qualiveen) questionnaire assesses the effect of bladder and urinary symptoms on patients' quality o … dy. The internal consistency of the total SF-Qualiveen, and the domains "Bother with limitations," "Fear," "Feeling," and "Frequency of limitations" showed good internal consistency (Cronbach's alpha of > 0.7). ICC was 0.91 for the total score 0.85 for the Bother with limitations, 0.81 for Fears, 0.86 for Feeling, and 0.81 for Frequency of limitations. …

Reappraisal is less effective than distraction in downregulation of neural responses to physical threats-An event-related potential investigation.

Evolutionary threats (ETs), such as predatory animals and heights, elicit stronger fear responses and are more often the subject of specific phobias, as compared to modern threats (MTs, such as guns and motorcycles). Since processing of ET depends on lower-order, phylogenetically conserved neural fear circuits, it may be less susceptible to higher-order (vs. simpler) cognitive emotion regulation. Given the relevance for treatment of specific phobias, we tested this hypothesis in an ERP study. Sixty-one female participants passively watched high- and low-threat pictures of evolutionary (snakes,…

Sex-specific effects of low-dose hydrocortisone on threat detection in HIV.

One sex differences in the perception of emotion is that females, particularly those with high anxiety, often show heightened identification of fearful faces. To better understand the causal role of glucocorticoids in this sex difference, we examine these associations in people with HIV(PWH) where emotion perception is impaired and mental health disorders are frequent. In a double-blind, placebo-controlled, cross-over study, we used a single low-dose of hydrocortisone (10 mg; LDH) as a mechanistic probe of the effects of elevated glucocorticoids on negative emotion perception in 65 PWH (31 wom…

Storytelling to Inspire Dialysis Patients to Learn about Living Donor Kidney Transplant.

BACKGROUND: Policy changes including the Advancing American Kidney Health initiative and CMS's ESRD Quality Incentive Program recommend increasing educational initiatives within dialysis centers to increase living kidney donor transplant (LDKT) rates. LDKT education can be challenging in dialysis centers due to limited provider time to educate, patient fears or reluctance to learn about LDKT, and difficulty educating potential living donors. New educational innovations that increase dialysis patient curiosity about pursuing LDKT are needed. SUMMARY: Digital first-person storytelling, or the s…

Parental feeding practices and the relationship with parents in female adolescents and young adults with eating disorders: A case control study.

OBJECTIVE: Perceived parental influence on diet in early adolescence in the context of the parental relationship had previously not been stu … analyses and mediator analyses. RESULTS: Adolescent and young adult females with ED reported more fears/overprotection and rejection/neglect by their mothers and less self-responsibility in terms of eating behaviour during adolescence than did the HC. The relationship with the fathers did not differ significantly. Females who perceived more cohesion, …

Emotional responses in monkeys differ depending on the stimulus type, sex, and neonatal amygdala lesion status.

The amygdala plays an essential role in evaluating social information, threat detection, and learning fear associations. Yet, most of that knowledge comes from studies in adult humans and animals with a fully developed amygdala. Given the considerable protracted postnatal development of the amygdala, it is important to understand how early damage to this structure may impact the long-term development of behavior. The current study examined behavioral responses toward social, innate, or learned aversive stimuli among neonatal amygdala lesion (Neo-Aibo; males = 3, females = 3) or sham-operated c…

A Feasibility Open Trial of a Brief Internet-Delivered Written Exposure Therapy for Worry.

BACKGROUND: Cognitive exposure, a treatment of choice for hypothetical fears, involves listening repeatedly to a recorded scenario of one's worst hypothetical fear. A major limitation, however, is that the script cannot be easily modified. AIMS: The current study assessed the feasibility of a brief guided internet-based written exposure therapy (iWET) for hypothetical fears, Mind at Peace. METHOD: Fifty-three adults presenting clinical levels of anxiety (GAD-7 ≥ 8) and worry (PSWQ ≥ 45) were recruited. A single group pre-test/post-test design including a 3-month follow-up was used. Mind at P…

Chronic social defeat stress induces sustained synaptic structural changes in the prefrontal cortex and amygdala.

Previous studies show that chronic stress induces synaptic structural alterations in brain regions involved in emotional processing such as … te in these regions the synaptic response to a friendly (interaction with a same strain mouse) or a fearful (interaction with a dominant strain mouse) social stimulus. Spine densities of the apical dendrites from the PFC pyramidal neurons were decreased by CSDS in the long-term (one month after CSDS). In addition, CSDS increased BLA stellate neurons sp …

Amygdala response to emotional faces in seasonal affective disorder.

BACKGROUND: Seasonal affective disorder (SAD) is characterized by seasonally recurring depression. Heightened amygdala activation to aversiv … m during summer and winter. We computed amygdala activation (SPM5) to an aversive contrast (angry & fearful minus neutral) and angry, fearful and neutral faces, separately. Season-by-group and main effects were evaluated using Generalized Least Squares. In SAD individuals, we correlated change in symptom severity, assessed with The Hamilton Rating Scal …

Empathic Accuracy in Male Adolescents with Conduct Disorder and Higher versus Lower Levels of Callous-Unemotional Traits.

Adolescents with disruptive behavior disorders are reported to show deficits in empathy and emotion recognition. However, prior studies have … an split. Participants watched films of actors recalling happy, sad, surprised, angry, disgusted or fearful autobiographical experiences and provided continuous ratings of emotional intensity (assessing EA), as well as naming the emotion (recognition) and reporting the emotion they experienced themselves (affective empathy). The CD and typically-develo …

[Value and acceptance of risk assessment for Alzheimer's disease].

BACKGROUND: It is quite common that people suffering from cognitive impairment only visit a doctor when the symptoms have already reached an advanced stage. This is often due to a fear of Alzheimer’s disease or a dread of exhausting diagnostic procedures and exposure of personal details; however, an early diagnosis and therapy increases the chance of preserving the quality of life for a longer period of time. OBJECTIVES: Evaluation of a risk assessment for Alzheimer’s disease by magnetic resonance imaging (MRI) with respect to the acceptance and value by participants. METHODS: In this prospe…

An fMRI study of emotional face processing in adolescent major depression.

BACKGROUND: Major depressive disorder (MDD) often begins during adolescence when the brain is still maturing. To better understand the neurobiological underpinnings of MDD early in development, this study examined brain function in response to emotional faces in adolescents with MDD and healthy (HC) adolescents using functional magnetic resonance imaging (fMRI). METHOD: Thirty-two unmedicated adolescents with MDD and 23 healthy age- and gender-matched controls completed an fMRI task viewing happy and fearful faces. Fronto-limbic regions of interest (ROI; bilateral amygdala, insula, subgenual …

Effects of acute psychosocial stress on neural activity to emotional and neutral faces in a face recognition memory paradigm.

Previous studies have shown that acute psychosocial stress impairs recognition of declarative memory and that emotional material is especial … performed an emotional face recognition task. During encoding, participants were presented with 50 fearful and 50 neutral faces. One hour later, they underwent either a stress (Trier Social Stress Test) or a control procedure outside the scanner which was followed immediately by the recognition session inside the scanner, where participants had to dis …

Sexual well-being of cervical cancer survivors under 50 years old and the factors affecting their libido.

OBJECTIVES: This paper aims to study the relationship between the sexual well-being and quality of life (QOL) of cervical cancer patients an … a sex life, the following reasons were given: 52.38% due to the side effects of treatments, 23.81% feared that sex would damage their surgical sites, 9.52% lacked libido, 9.52% feared that sex would make their conditions worse, and 4.76% feared that having sex would transmit the disease to their spouses. After adjusting the age and survival time, the …