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COVID-19: The Impact in Oncology Care.

The COVID-19 pandemic has imposed a critical challenge to the current oncology care and practices including late diagnoses, delayed anti-cancer treatment, and static clinical trials. With the increasing risk of cancer patients acquiring infection during receiving the essential care, the debate ensues on how to balance the risk factors and benefits out of the oncologic emergencies in cancer patients. In this review article, we have focused on the current global re-organization of the integrity and effectiveness of the treatment modalities depending on the patient and cancer-specific urgencies w

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… Depending on the lethality associated with these cancers, the oncologists are not modifying the therapy regimens despite the COVID-19 risk. … With the continuation of the crisis period, the oncologists report unparalleled levels of companionship and cooperation to share responsibility across the world. …

The SMARTIE Program: A Novel Initiative to Evaluate the Impact of AP Continuing Education on Clinical Practice.

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… However, a steadily growing proportion (19.8%) of oncologists is nearing retirement age ( ASCO, 2015 ), and older oncologists continue to outnumber the 13.9% of oncologists less than 40 years old who have recently entered the field ( ASCO, 2016 ). … Oncologists working collaboratively with APs report improved efficiency, higher professional satisfaction, and improved patient satisfaction ( Towle et al., 2011 ). …

Расовые различия в миеломе и доступ к трансплантации стволовых клеток.

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… Lin CC Bruinooge SS Kirkwood MK Olsen C Jemal A Bajorin D Association between geographic access to cancer care, insurance, and receipt of chemotherapy: geographic distribution of oncologists and travel distance J Clin Oncol 2015 33 3177 85 10.1200/JCO.2015.61.1558 26304878 PMC4979096 Lin CC, Bruinooge … Association between geographic access to cancer care, insurance, and receipt of chemotherapy: geographic distribution of oncologists and travel distance. J Clin Oncol. 2015;33:3177–85. 26304878 10.1200/JCO.2015.61.1558 PMC4979096 20. …

Duodenal plasmablastic lymphoma in an human immunodeficency virus-negative patient: a case report.

BackgroundPlasmablastic lymphoma is a rare type of non-Hodgkin lymphoma that generally presents an aggressive clinical course. It is strongly associated with human immunodeficency virus (HIV) infection, and the most common site of involvement is the oral cavity. Although extraoral PBL has been reported in several places, small intestine involvement is extremely rare.Case presentationHere, we describe an exceptionally rare case of a 24-year-old immunocompetent Asian Male patient with newly diagnosed plasmablastic lymphoma of the duodenum. The patient was admitted to our oncology facility due to

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… For oncologists, the diagnosis of PBL in immunocompetent and extraoral site localization is very demanding because the clinical, morphological, phenotypic, and molecular features are ambiguous. … As remission is achieved by induction chemotherapy [ 7 ] and hematopoietic stem cell transplantation is also considered a good option in the management of PBL [ 10 ], oncologists should conduct trials with this combination for a better cure. …

A Pilot Program Implementing an Evidence-Based Walking Plan to Improve Cancer-Related Fatigue in Adult Patients on Oral Cancer Treatments.

BackgroundFatigue is a prevalent symptom among cancer patients, even after completing treatment. The National Comprehensive Cancer Network Guidelines recommend incorporating physical activity as a strategy to combat cancer-related fatigue.ObjectivesThe goal was to develop and implement an evidence-based translational research quality improvement project to improve fatigue in patients starting oral cancer treatment.MethodsOutpatient oncology nurses (registered nurses and licensed practical nurses) responsible for educating patients starting treatment for cancer were provided education about the

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… To support this initiative, a patient education brochure and nursing education presentation were developed, providing information on the benefits of walking, suggestions for questions to ask oncologists, tips for creating personalized walking plans, preparation guidelines, goal-setting strategies, safety … At the time of the project's initiation, ICRC's multidisciplinary team was comprised of 47 medical oncologists, 10 radiation oncologists, 12 breast surgeons, 2 gynecologic oncologists, 9 urologists, 16 advanced practice providers, and 1 integrative oncologist. …

Transitions of care for advanced cancer in post-acute and long-term care.

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… This is routinely performed by the interprofessional PALTC team but is rarely accessible to outpatient oncologists. … The CGA data obtained at the PALTC facility should be shared with the oncologist in order to improve how they gauge tolerability and the possible need to adapt the treatment plan to minimize the risks of under- and overtreatment. 16 CGAs can also help identify drivers of frailty that can be monitored …

Разработка Novel Digitals Eliction Measure for Clinical Use у пожилых людей с гематологическими злокачественными свойствами: Ценности-HM.

Введение. Недавнее расширение возможностей лечения пожилых людей, страдающих раком крови, повысило необходимость понимания предпочтений и ценностей пациентов для принятия решений о лечении. В настоящее время для клинического применения в этой группе населения не было подтверждено никаких мер по расчету значений. Величины-HM (показатель вымогательства для гематологовых злоумышленников) представляют собой новый показатель вымогательства, основанный на наилучших значениях масштаба. Он был разработан специально для пожилых людей, страдающих раком крови, с участием многих заинтересованных сторон, в

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… After completing their initial consultation with their oncologist, participants were prompted to complete additional surveys and Values-HM. … Treatment decision-making in acute myeloid leukemia: a qualitative study of older adults and community oncologists . Leuk Lymphoma . 2021 ; 62 ( 2 ):387–98. DOI: 10.1080/10428194.2020.1832662 PMC7878016 33040623 19 Bröckelmann PJ McMullen S Wilson JB , et al . …

Development of Web-Based Education Modules to Improve Carer Engagement in Cancer Care: Design and User Experience Evaluation of the e-Triadic Oncology (eTRIO) Modules for Clinicians, Patients, and Carers.

BackgroundCarers often assume key roles in cancer care. However, many carers report feeling disempowered and ill-equipped to support patients. Our group published evidence-based guidelines (the Triadic Oncology [TRIO] Guidelines) to improve oncology clinician engagement with carers and the management of challenging situations involving carers.ObjectiveTo facilitate implementation of the TRIO Guidelines in clinical practice, we aimed to develop, iteratively refine, and conduct user testing of a suite of evidence-based and interactive web-based education modules for oncology clinicians (e-Triadi

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… Oncologists have reported a lack of education about communicating with carers [ 10 ], and suboptimal carer-clinician communication is common [ 11 ]. Some carers report being overlooked in medical consultations and feeling disempowered and unprepared in their caregiving role [ 12 ]. … A clinician expert advisory group was formed to provide feedback about the module content, comprising medical oncologists (3/13, 23%), oncology nurses (2/13, 15%), psychologists (2/13, 15%), a radiation oncologist (1/13, 8%), an oncology surgeon (1/13, 8%), and the research team comprising psycho-oncologists …

Deciphering the Patterns of Dual Primary Cases Registered at the Hospital-Based Cancer Registry: First Experience from Rural Cancer Center in North India.

Objectives The objective is to present the patterns of dual primary malignancies diagnosed at the Pathology Laboratory of Cancer Hospital with the support from hospital-based cancer registry (HBCR), Sangrur, Punjab, India for the years 2018 and 2019. Methods HBCR abstracts data from electronic medical records. Trained cancer registry staff abstracts cases in standard pro forma. Dual primary was coded as per the International Agency for Research on Cancer rule and was rechecked by the pathologist. Statistical Analysis Data about multiple primary was entered and documented in an Excel sheet. Tim

Cancer treatment delays among cancer patients living with HIV during the COVID-19 pandemic in the United States.

BackgroundThe COVID-19 pandemic led to care disruptions across the cancer continuum. It is unknown if immunosuppressed patients with cancer, who may be at higher risk for complications of SARS-CoV-2 infection, are disproportionately impacted. Thus, we aimed to compare delays in cancer treatment initiation between people living with HIV (PLWH) and cancer, the general cancer population (GCP), and patients with cancer and a history of solid organ transplant (SOT). Comparisons were made across the period 2 years preceding the pandemic versus the first year of the pandemic.MethodsWe used data from

Implementation of Physical Activity Programs for Rural Cancer Survivors: Challenges and Opportunities.

Physical activity after cancer diagnosis has been consistently associated with improvements in quality of life and prognosis. However, few cancer survivors meet physical activity recommendations, and adherence is even lower among those living in rural settings. The purpose of this quasi-experimental study was to evaluate the implementation of a clinic-based physical activity program for cancer survivors at a rural community oncology setting. We also examined changes in quality-of-life measures among 24 cancer survivors participating in the physical activity program and described challenges and

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… The effect of oncologists’ exercise recommendations on the level of exercise and quality of life in survivors of breast and colorectal cancer: A randomized controlled trial. Cancer. 2015;121:2740–2748. doi: 10.1002/cncr.29400. 32. … Oncologists’ attitudes and practice of addressing diet, physical activity, and weight management with patients with cancer: Findings of an ASCO survey of the oncology workforce. J. Oncol. Pract. 2019;15:e520–e528. doi: 10.1200/JOP.19.00124. 36. …

Morphometrics predicts overall survival in patients with multiple myeloma spine metastasis: A retrospective cohort study.

BackgroundTreatment strategies for spinal metastases for myeloma range from conservative measures (radiation and chemotherapy) to invasive (surgical). Identifying better predictors of overall survival (OS) would help in surgical decision making. Analytic morphometrics has been shown to predict survival in oncologic patients, and our study evaluates whether morphometrics is predictive of survival in patients with multiple myeloma (MM) spinal metastases.MethodsFor this observational retrospective cohort study, we identified 46 patients with MM spinal metastases who had undergone stereotactic bod

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… Each patient was discussed in a multidisciplinary spine tumor board attended by radiation oncologists, neurosurgeons, neuroradiologists, and medical oncologists. Recommendations regarding whether a patient was a suitable candidate for spine SRS were made based on consensus opinion. … Oncologist. 2013;18:744–51. doi: 10.1634/theoncologist.2012-0293. 31. Lee BH, Park JO, Kim HS, Park YC, Lee HM, Moon SH. Perioperative complication and surgical outcome in patients with spine metastases: Retrospective 200-case series in a single institute. …

Clinically significant bleeding in incurable cancer patients: effectiveness of hemostatic radiotherapy.

BackgroundThis study was performed to evaluate the outcome after hemostatic radiotherapy (RT) of significant bleeding in incurable cancer patients.MethodsPatients treated by hemostatic RT between November 2006 and February 2010 were retrospectively analyzed. Bleeding was assessed according to the World Health Organization (WHO) scale (grade 0 = no bleeding, 1 = petechial bleeding, 2 = clinically significant bleeding, 3 = bleeding requiring transfusion, 4 = bleeding associated with fatality). The primary endpoint was bleeding at the end of RT. Key secondary endpoints included overall survival (

Exploring the implementation of patient-reported outcome measures in cancer care: need for more real-world evidence results in the peer reviewed literature.

BackgroundTo explore the existing evidence of the real-world implementation of patient-reported outcomes (PROs) in oncology clinical practice and address two aims: (1) summarize available evidence of PRO use in clinical practice using a framework based on the International Society for Quality of Life Research (ISOQOL) PRO Implementation Guide; and (2) describe reports of real-world, standardized PRO administration in oncology conducted outside of scope of a research study.MethodsA Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) protocol was developed to guide the sy

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… Patients' and oncologists' preferences for discussing health-related quality-of-life issues. J Clin Oncol. 2000;18(18):3295–3301. doi: 10.1200/JCO.2000.18.18.3295. 7. Levine MN, Gafni A, Markham B, MacFarlane D. … Physicians' perspective on quality of life: An exploratory study of oncologists. Qual Life Res. 1996;5(1):5–14. doi: 10.1007/BF00435963. 12. …

Relationship between Drug Holidays of Antiresorptive Agents and Surgical Outcomes in Cancer Patients with Medication-Related Osteonecrosis of the Jaw.

It is controversial as to whether the withdrawal of antiresorptive (AR) agents is necessary while treating medication-related osteonecrosis of the jaw (MRONJ). In this study, we investigated whether a drug holiday promoted sequestrum separation and improved the surgical outcomes of MRONJ patients with malignant tumors, who were undergoing high-dose AR therapy. In total, we included 103 MRONJ patients with malignant tumors as their primary disease who underwent surgery at Nagasaki University Hospital or Kansai Medical University Hospital from January 2009 to December 2020. We recorded the patie

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… We encouraged oncologists to not withdraw AR agents for the purpose of treating MRONJ, but to administer them (if necessary) for the treatment of the primary disease. However, several patients had drug holidays of AR agents at the discretion of their oncologists. … Cancer can progress rapidly; thus, we immediately try to perform surgery for MRONJ without any drug holiday after consulting patients and oncologists. …

The role of postoperative radiation and coordination of care in patients with metastatic bone disease of the appendicular skeleton.

Metastatic bone disease affects approximately 300,000 people in the United States, and the burden is rising. These patients experience significant morbidity and decreased survival. The management of these patients requires coordinated care among a multidisciplinary team of physicians, including orthopaedic surgeons. This article reviews the role of radiation therapy after orthopaedic stabilization of impending or realized pathologic extremity fractures. Orthopaedic surgeons have an opportunity to benefit patients with metastatic bone disease by referring them for consideration of post-operativ

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… , medical oncologists, palliative care, and orthopaedic surgeons. 13 Mirels developed a widely reported scoring system to predict pathologic fracture risk. 14 This system takes into account the location, size, and type of lesion, as well as the amount of pain the patient is experiencing, with a score … They found that a group of oncologists treating patients with long bone metastasis failed to refer patients to orthopaedics at a consistent rate; 16/37 patients in this study had a Mirels score of 8 or greater, 5/37 had a score equal to 8, and 16/37 had a score less than 8. …

The Landscape of COVID-19 in Cancer Patients: Prevalence, Impacts, and Recommendations.

Cancer patients are susceptible groups to COVID-19, and risk-adjusted models show that most cancer patients have a 25-39% mortality risk if infected with COVID-19. The infection rate of SARS-CoV-2 in cancer patients in China was 0.79% (12 of 1524 patients; 95% CI, 0.31.2%). The case fatality rate of COVID-19 in the overall population ranges from 2.3 to 8.0%; among these, the case fatality rate for cancer patients is at 5.6%. In a retrospective cohort study of 28 COVID-19-infected cancer patients, a total of 15 (53.6%) patients had severe outcomes with a mortality rate of 28.6%. In a pooled ana

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… With scarce resources, Oncologists should prioritize what treatments are most likely to be successful, symptom-relieving, and which patients are likely to benefit from such treatments. Finally, Oncologists should always be compassionate and do no harm–primum non nocere. … Secondly, a COVID-19 ad hoc expert committee comprising of infectious disease experts, hematologists and oncologists, pharmacists and radiologists has been set up and institutional guidelines put in place. …

No blood transfusion for my own anaemia-tit for tat?

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… Oncologists insisted on continuing therapy, and said, ‘You have to be patient’. Now, several problems manifested. A breathing frequency of 30/min whilst at rest. Interrupted speaking as I had to catch my breath frequently. … Like a vampire, I dreamed of a bag in a vital red colour, infusing my port, but my oncologists said ‘No’—as long as my Hb value was greater than 8 g/l. Tit for tat? …

Доступ к терапии перенаправления T-Cell в Мультимиломе: пациент, сторож и физиологическая точка зрения на осведомленность и барьеры.

Справочная информация: Лечение перенаправления Т-клеток (TCRTs), включая терапию CAR-T-клеток и биконкретные антитела, изменило методы лечения повторной/охлажденной множественной миеломы (MM), однако реальное усыновление по-прежнему ограничено из-за ограничений в плане осведомленности и доступа пациентов, лиц, обеспечивающих уход, и врачей. Методы: Мы провели перекрестное исследование (июнь-сентябрь) 2025) с использованием одобренных IRB обследований СВОД, распространяемых среди пациентов, имеющих MM (через MyChart), лиц, обеспечивающих уход за получателями ТСПР (по электронной почте) и общинн

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… Referring physicians most often cite financial toxicity as the primary barrier, whereas treating oncologists emphasize logistical concerns such as leukapheresis slot availability and hospitalization requirements [ 14 ]. … Referral to TCRT was common (71%), with all hematologists reporting referrals, compared to 86% referred among medical oncologists and 57% referred among non-oncology specialties; however, nearly half (48%) reported that fewer than a quarter of referred patients proceeded with treatment. …

Cardiovascular Complications of Novel Anti-Cancer Immunotherapy: Old Problems from New Agents?

Many novel anti-cancer therapies have dramatically improved outcomes of various cancer patients. However, it also poses a risk for cardiovascular complications as well. For the novel anti-cancer agent with which physicians does not have enough clinical experiences to determine the characteristics of cardiovascular complications, it is important to assess risk factors for cardiotoxicity before starting anti-cancer therapy. High-risk patient should be consulted to cardiologist before initiating anti-cancer therapy and pre-emptive cardiac function monitoring plan might be prepared in advance. The

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… Sharing information of novel anti-cancer agents and treatment schedule can help not only cardiologist but also oncologist to manage unexpected cardiotoxic complication of new agents. … Post treatment surveillance can be also discussed and planned before initiating cancer treatment between cardiologists and oncologists. …