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TsAg5, a Taenia solium cysticercus protein with a marginal trypsin-like activity in the diagnosis of human neurocysticercosis.

Neurocysticercosis is an endemic parasitic disease caused by Taenia solium larva. Although the mechanism of infection is not completely understood, it is likely driven by proteolytic activity that degrades the intestinal wall to facilitate oncosphere penetration and further infection. We analyzed the publicly available T. solium EST/DNA library and identified two contigs comprising a full-length cDNA fragment very similar to Echinococcus granulosus Ag5 protein. The T. solium cDNA sequence included a proteolytic trypsin-like-domain in the C-terminal region, and a thrombospondin type-1 adherence…

Управление и уход за африканскими общежитиями (Graphiurus kelleni).

Африканские общежития (Graphiurus spp.) представляют собой небольшие ночные грызуны, которые в настоящее время редко встречаются в лабораторных условиях. Их использование может возрасти, поскольку недавно было доказано, что они развивают инфекцию с вирусом обезьянопокс и могут оказаться ценной моделью животных для исследований инфекционных заболеваний. Поскольку африканское общежитие не доступно на рынке, для производства животных, необходимых для исследований, требуется обширная колония разведения. Изменения в муже, которые привели к увеличению производства потомства, были связаны с использов

Совпадение в аннотации оригинала
African dormice (Graphiurus spp.) are small nocturnal rodents that currently are uncommon in laboratory settings. Their use may increase as … tability of several high-protein foods in a series of preference trials. Dormice preferred wax worm larva, cottage cheese, roasted soy nuts, and canned chicken. Issues related to medical management of Graphiurus kelleni include potential complications from traumatic injury. The development of a program for the husbandry and care of African dormice at ou …

Environmental contamination by Toxocara spp. eggs in a rural settlement in Brazil.

In order to study the environmental contamination by Toxocara spp. eggs in a rural community from the Pontal do Paranapanema region, São Pau … s of the inhabitants may be an important risk factor for the human population to ocular or visceral larva migrans.

[Human dirofilariasis: 3 cases in the south of France].

INTRODUCTION: Dirofilariasis is a zoonosis usually found in dogs and cats. It is rare in humans, who are dead-end hosts for the parasite. C … mosquito bites (Aedes, Culex, Anopheles, Mansonia, Psorophora and Taeniorhynchus). Usually only one larva develops, producing an immature adult worm inside a node. Ultrasound examination may suggest the parasitic origin of the lesion. It is treated surgically, by excision, without chemotherapy. Very rarely, an adult worm may mature and produce systemic …

Hepatic toxocariasis: US, CT and MRI findings.

Visceral larva migrans (VLM) most commonly occurs as a febrile disease of childhood particularly affecting children between 1 and 7 years of age. Pulmonary, dermatological, hepatic, lymphatic, cardiac, rheumatological and neurological manifestations may occur. VLM seems to be a rare disease in adults. We report the imaging findings of a woman with hepatic toxocariasis. Ultrasonography showed a solitary hepatic lesion measuring 4 x 3 cm, displaying a hypoechoic-heterogeneous pattern with ill-defined borders and distal acoustic enhancement, located in the right sub-diaphragmatic area. Two enlarg…

Human botfly infestation presenting as peri-auricular mass.

To report a new cause of peri-auricular mass in children: cutaneous myiasis-botfly infestation. Case report. The human botfly (Dermatobia hominis) is found in the tropics of Central and South America. However, cases of infestation are uncommon in the United States. We present the case of a 5-year-old girl with cutaneous myiasis in order to expand the differential diagnosis for a peri-auricular mass in children. In our report, the parasite was initially identified as sparganum, but was later reclassified by the center for disease control and prevention (CDC) as a botfly larva. Parasitic infecti…

High incidence of the gullet worm, Gongylonema pulchrum, in a squirrel monkey colony in a zoological garden in Japan.

Histological examination revealed the gullet worm (Gongylonema pulchrum) embedded in the lingual mucosa of two of four dead Bolivian squirrel monkeys (Saimiri boliviensis) from a zoological garden in Kyushu, Japan. The zoo had kept the monkeys as a colony of approximately 80-100 individuals in a moated, open ground since 1981. To assess the incidence of G. pulchrum infection in this colony, lingual scraping with disposable plastic sticks was conducted in February during 2 consecutive years (2003 and 2004). The oval, thick-shelled egg containing a larva was found in 15 of 27 arbitrarily-chosen …

Use of laser rhinoscopy to treat a nasal obstruction in a captive California sea lion (Zalophus californianus).

Laser rhinoscopy was used to treat a nasal obstruction in a captive California sea lion (Zalophus californianus). The rehabilitated, adult, … on tissue with suppurative inflammation, bacterial infection, and a partial section of an arthropod larva (not speciated). Laser rhinoscopy was performed to relieve the caudal nasopharyngeal obstruction and ablate the polyps. The sea lion appeared to breathe through the nares with lessened nasal discharge for a period of 6 wk after laser therapy, but wi …

Toxocariasis of the central nervous system: with report of two cases.

Clinical involvement of the nervous system in visceral larva migrans due to Toxocara is rare, although in experimental animals the larvae frequently migrate to the brain. A review of the literature from the early 50's to date found 29 cases of brain involvement in toxocariasis. In 20 cases, various clinical and laboratory manifestations of eosinophilic meningitis, encephalitis, myelitis or radiculopathy were reported. We report two children with neurological manifestations, in which there was cerebrospinal fluid pleocytosis with marked eosinophilia and a positive serology for Toxocara both in …

Efficacy of ivermectin in a patient population concomitantly infected with intestinal helminths and ectoparasites.

Ivermectin (CAS 70288-86-7) is a potent antiparasitic drug. However, studies have not been published evaluating the efficacy of ivermectin i … okworm disease, and 50% for hymenolepiasis. Cure rates for ectoparasitoses were: 100% for cutaneous larva migrans, 99% for pediculosis, 88% for scabies and 64% for tungiasis. The results show that two doses of ivermectin are highly efficacious for most intestinal helminths and ectoparasites simultaneously present in an impoverished population. The drug …

Immunological genomics of Brugia malayi: filarial genes implicated in immune evasion and protective immunity.

Filarial nematodes are metazoan parasites with genome sizes of> 100 million base pairs, probably encoding 15 000-20 000 genes. Within this c … d stage-specific surface proteins, as well as products associated with the mosquito-borne infective larva which offer the best opportunity for an anti-filarial vaccine. These gene products provide a fascinating glimpse of the molecular repertoire which helminth parasites have evolved to manipulate and evade the mammalian immune response.

The Simulium damnosum complex in western Uganda and its role as a vector of Onchocerca volvulus.

The status of onchocerciasis vectors in the former Ruwenzori focus in western Uganda was re-examined some 15 years after control measures ag … a vector south of the Ruwenzori (Kasese focus), where 15.4% of the parous flies were infected with larval stages of Onchocerca volvulus and 34 infective larvae were found in the heads of 1000 parous flies. In the second focus along the Mahoma and Nsonge rivers, a chromosomally highly polymorphic population of S. kilibanum had replaced the former vector …

Involvement of regional lymph nodes after penetration of Schistosoma mansoni cercariae in naive and infected mice.

The parotid lymph nodes of naive and previously infected Balb/c mice were studied after, respectively, infection and re-infection with cerca … fected and re-infected mice. However, only in the latter the eosinophils were able to adhere to the larval surface. In primarily-infected mice, no intranodal larva presented signs of degeneration. In contrast, in re-infected animals, some degenerating larvae were found inside eosinophilic infiltrates. The eosinophils reached the nodal tissue by migratin …

A comparison of parasitic helminths and arthropods from two subspecies of fox squirrels (Sciurus niger) in Florida.

The faunas of parasitic helminths and arthropods of 87 Sherman's fox squirrels (Sciurus niger shermani) and 32 Big Cypress fox squirrels (Sciurus niger avicennia) collected from Florida (USA) over a 6-yr period (1988 to 1993) were compared. One acanthocephalan, one cestode, nine nematodes, one flea, three sucking lice, three mites, one tick, and one dipteran larva were identified. Citellinema bifurcatum and Physaloptera massino were new records for Florida and Gongylonema pulchrum, Neotrombicula whartoni, and Eushoengastia diversa were new host records. Three core species of nematodes (distrib…

[Intestinal helminthiasis--general practice problem of the gastroenterologist].

In case of nonspecific, not constantly occurring abdominal symptoms the investigator should be aware of invermination, especially when immig … nd Vampirolepis are predominant. Trematodes = Fasciola, Echinostoma, Schistosoma are less frequent. Larva migrans, Acanthocephala and Dipylidium sometimes cause considerable diagnostive problems. Classification of macroscopic and microscopic findings is decisive for the therapeutic strategy. For nematodiasis Mebendazole (Vermox, Surfont), Pyrantelembona …

Evidence for the involvement of cyclic AMP in the pheromonal modulation of barnacle settlement.

The involvement of cyclic AMP in the settlement of the cypris larva of Balanus amphitrite amphitrite Darwin has been examined through the use of compounds that affect intracellular cyclic AMP levels. The activation of adenylate cyclase with forskolin, and the inhibition of phosphodiesterase with 3-isobutyl-1-methylxanthine, caffeine and theophylline, significantly increased the settlement of cyprids. Although the analogue dibutyryl cyclic AMP appeared to increase settlement, the effect was not significant. No marked increase in settlement resulted from the incubation of cyprids with dibutyryl …

Tissue localization of excretory-secretory antigens of larval Toxocara canis in acute and chronic murine toxocariasis.

The distribution of excretory-secretory antigens of larval Toxocara canis (TEX) in tissue was studied in cases of both acute and chronic experimental murine toxocariasis. Liver samples were collected from BALB/c BYJ mice killed either 2 days (acute) or 8 months (chronic) after intragastric inoculation with infective T. canis eggs. Cryostat sections of liver were stained using biotin-conjugated, rabbit anti-TEX antibody with an avidin-fluorescein isothiocyanate indicator. In both acute and chronic infections larval sections were brightly fluorescent. The patterns of antigen deposition in acute …

[The sensory neuropile of the nerve chain of Eurygaster integriceps P].

Structure of the sensory neuropil of the abdominal nervous chain has been studied in the Eurygaster integriceps P. by means of methylene blue and paraldehyde fuchsin with phloxin staining. The sensory neuropil consists of three parts: 1) main sensory neuropil, including terminal, T-shaped, antero- and posterconnective fibers; 2) lateral sensory neuropils of the extremities, that in the insect studied, as in the dragon-fly larva, have the form of the overturned eight; 3) system of thick T-shaped fibers getting into the first thoracic ganglion and running along the second nerves, as well as alon…

Human toxocariasis in a rural community.

A questionnaire and serologic survey of a Pennsylvania community revealed that 23 (54%) of 43 study participants had antibody titers to Toxo … lthough medical examination and laboratory tests revealed a few abnormalities, neither the visceral larva migrans syndrome nor the ocular lesions characteristic of those produced by Toxocara sp were observed in any individual. We conclude that although certain populations may have high seropositivity rates to Toxocara antigens, indicating previous infec …

Achaete-Scute-Like 1a Expression Is Essential for the Generation of Correct Proportions of Neuron Subtypes in the Developing Enteric Nervous System of Zebrafish (Danio rerio).

BACKGROUND AND AIMS: The enteric nervous system (ENS) mediates many gastrointestinal functions and develops through processes involving transcription factors, including achaete-scute-like 1a (Ascl1a). In zebrafish, the contribution of Ascl1a to enteric neuronal specification remains unclear, which we aim to unravel. METHODS: We examined spatiotemporal Ascl1a expression in the ENS of wild-type (WT) zebrafish larvae using quantitative polymerase chain reaction (qPCR) and immunofluorescence staining. Ascl1a function was investigated using pia t25215 zebrafish (Ascl1a -/- ). Immunofluorescence st…