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A Novel Natural Chromogenic Visual and Luminescent Sensor Platform for Multi-Target Analysis in Strawberries and Shape Memory Applications.

Carboxymethyl cellulose (CMC) films, derived from sugarcane bagasse agricultural waste (SCB) incorporated with Betalains-nitrogen-doped carbon dots (Betalains-N-CQDs), derived from beet root waste (BR), offer a sustainable, smart and naked-eye sensor for strawberry packaging due to their excellent fluorescent and shape memory properties. These CMC-Betalains-N-CQDs aim to enhance strawberry preservation and safety by enabling visual detection of common food contaminants such as bacteria, fungi and Pb(II). Crucially, the CMC-Betalains-N-CQD film also exhibits excellent shape memory properties, c…

Prophylactic Effects of Rhamnetin Flavonoid on Indomethacin-Induced Gastric Ulceration by Modulating HSP 70/Bax, SOD/MDA and TNF-α/IL-10.

Rhamnetin is a naturally occurring flavonoid compound found in many wild plant species and indigenous fruits. Despite its numerous biologica … : a negative control group (A) and a positive control group (B), both treated with 1% carboxymethyl cellulose; a reference group (C) receiving 20 mg/kg omeprazole; and low-dose (D) and high-dose (E) rhamnetin groups receiving 30 and 60 mg/kg, respectively. After 1 h, rats in Groups B-E were subjected to indomethacin-induced ulceration. Toxicity evaluations …

Constructing a hemostatic sponge loaded with copper nanoparticles and carboxymethyl chitosan for wound hemostasis and infection prevention.

Uncontrolled hemorrhage and infection pose serious risks to patient survival, highlighting the critical need for multifunctional hemostatic … ompromised by drug-resistant bacteria. Utilizing the natural hemostatic properties of carboxymethyl cellulose (CMC), this material facilitates swift coagulation via electrostatic interactions that enhance the adhesion and aggregation of blood cells. Concurrently, copper nanoparticles (Cu-NPs) are synthesized in situ through redox reactions with copper ions …

Modulation of hyperglycemia, insulin resistance responses and gut microbiota composition in type 2 diabetic mice by capsicum residue soluble dietary fiber.

Type 2 diabetes mellitus (T2DM) poses substantial health risks, emphasizing the need to identify natural ingredients from biological sources … and porous with a rough surface. It exhibited characteristic polysaccharide absorption peaks and a cellulose I crystalline structure. After four weeks of CR-SDF intervention, T2DM mice showed improvements in glucose and lipid levels, insulin resistance, and liver and pancreas health. Analysis of fecal SCFAs revealed increased concentrations in diabetic mic …

Efficacy of yeast-mediated SeNPs on gastric ulcer healing and gut microbiota dysbiosis in male albino rats.

BACKGROUND: Gastric ulcer is one of the most common gastrointestinal tract diseases with a higher extent in male patients. Selenium nanoparticles (SeNPs) possess therapeutic benefits, including antimicrobial, antioxidant, anti-inflammatory, and anti-ulcerative agents. The study aimed to investigate the modulatory effect of yeast-mediated SeNPs on gastric ulcers and microbiota dysbiosis in a rat model. METHOD: Twenty-four rats were randomly divided into four groups. Both the control and SeNPs-only groups received distilled water orally, and after 1 h, they received 2 % carboxymethyl cellulose …

Effect of Temperature and Relative Humidity on CO2 Adsorption Performance of Biomass-Derived Aerogels.

The safe and efficient capture of CO2 in confined environments such as coal mine goafs remains a significant challenge, posing both environm … an 18% increase in CO2 adsorption capacity compared to room temperature. The sample with a 1:1 high cellulose ratio is primarily dominated by physical adsorption, making its performance susceptible to environmental fluctuations. The sample with a 1:3 high chitosan ratio is predominantly governed by chemical adsorption, exhibiting more stable adsorption char …

A metabolic reprogramming and trained immunity hydrogel mimic cluster missiles to eliminate infection and treat infected diabetic wounds.

Excessive inflammation, infection, persistent reactive oxygen species (ROS) accumulation, hyperglycemia, and vascular lesions in diabetic ch … hydrogel (CMC-PDA/GEL) was created by combining gelatin (GEL) with catechol-modified carboxymethyl cellulose (CMC-DA). Composite hydrogel dressings in CVCeCG were created by adding polycaprolactone microspheres loaded with calcium peroxide (CPO@PCL) or vancomycin (Van@PCL) and cerium oxide nanoparticles (CeNPs) to CMC-PDA/GEL. This hydrogel can mimic missi …

Deciphering the mechanism for encapsulation of MOF (Fe-glutaric acid) onto Se/SnO2 embedded CMC for effective aqueous sequestration of pharmaceutical pollutant via adsorption.

Wastewater is commonly contaminated with many pharmaceutical pollutants, so an efficient purification method is required for their removal from wastewater. In this regard, an innovative tertiary Se/SnO2@CMC/Fe-GA nanocomposite was synthesized through encapsulation of metal organic frameworks (Fe-glutaric acid) onto Se/SnO2-embedded-sodium carboxy methyl cellulose matrix to thoroughly evaluate its effectiveness for adsorption of levofloxacin drug from wastewater. The prepared Se/SnO2@CMC/Fe-GA nanocomposite was analyzed via UV-Vis spectroscopy, Fourier-transform infrared spectroscopy (FTIR), sc…

Enantioseparation of Proton Pump Inhibitors by HPLC on Polysaccharide-Type Stationary Phases: Enantiomer Elution Order Reversal, Thermodynamic Characterization, and Hysteretic Effect.

The separation of three proton pump inhibitors (omeprazole, lansoprazole, and rabeprazole) as exemplified molecules containing chiral sulfoxide groups was investigated in polar organic liquid chromatographic mode on seven different polysaccharide stationary phases (Chiralcel OD and OJ; Chiralpak AD, AS, and IA; Lux Cellulose-2 and -4). Different alcohols, such as methanol, ethanol, 1-propanol, 2-propanol, and their combinations, were used as eluents. After method optimization, semi-preparative enantioseparation was successfully applied for the three proton pump inhibitors to collect the indivi…

Anemoside B4 Rectal Thermosensitive In Situ Gel to Treat Ulcerative Colitis by Overcoming Oral Bioavailability Barriers with Absorption Enhancer-Assisted Delivery.

Background: Anemoside B4 (AB4), the major bioactive saponin from Pulsatilla chinensis, exhibits anti-inflammatory, anti-tumor, anti-apoptoti … formulation variables such as poloxamer 407 (P407), poloxamer 188 (P188), and hydroxypropyl methyl cellulose (HPMC) were optimized, employing single-factor experiments coupled with the Box-Behnken design response surface methodology (BBD-RSM). Comprehensive characterization encompassed in vitro release kinetics, in vivo pharmacokinetics, rectal tissue tole …

Effects of Acute Caffeine Intake on Endurance Performance and Cardiac Autonomic Modulation in Patients with COPD.

OBJECTIVE: This study aimed to investigate the effects of acute caffeine (CAF) intake on heart rate, time to exhaustion, and cardiac autonom … r achieved in the maximal incremental exercise test) after ingestion of CAF (5 mg.kg-1) or placebo (cellulose, PLA) 60 min before the test. Heart rate (HR) and heart rate variability (HRV) were continuously monitored beat-to-beat throughout the test and recovery using a portable HR monitor. RESULTS: During exercise, the response of HR showed a significant …

Dissolving Microneedles Containing Lactoferrin Nanosuspension for Enhancement of Antimicrobial and Anti-Inflammatory Effects in the Treatment of Dry Eye Disease.

Background/Objectives: Dry eye disease (DED), also known as "keratoconjunctivitis sicca", is a common chronic ocular surface disease accompa … ). Optimized BLF-NS was then incorporated with polyvinyl pyrrolidone (PVP) and hydroxypropyl methyl cellulose (HPMC) dissolving microneedles (MNs). The formulations were characterized by Scanning and transmission microscopy, DSC, FTIR, ex vivo studies in corneal tissue from sheep and tested for its antibacterial and antifungal efficacy against Methicillin-R …

Clinical characteristics and transabdominal ultrasound features that associated with T3-T4 staging in gastric cancer: A retrospective study.

BACKGROUND: Transabdominal ultrasound after the oral administration of an echoic cellulose-based gastric ultrasound contrast agent has recently been suggested to be effective in T staging of gastric cancer (GC). AIM: To explore the clinical characteristics and transabdominal features associated with T3-T4 staging of GC. METHODS: In total, 113 patients who underwent transabdominal ultrasonography and had confirmed GC based on surgical pathology were included. Variables including clinical characteristics [age, body mass index, gender, clinical features, pathological type, histologic type, Laur…

Coenzime Q10 Modulds BDNF и он регулирует некодирование RNA для аттенуативных моторных дефицитов и нейродегенерации в мозге Crebellum Cuprizon-Invested Demyelination Rat Model.

Множественный склероз (MS) — прогрессивное нейродегенеративное расстройство. Имеются ограниченные данные о молекулярных механизмах, лежащих в основе участия мозжечников, и потенциальной роли Coenzime Q10 (CoQ10) в некодировании РНК в РС. Цель этого исследования заключалась в изучении воздействия CoQ10 на гистоморфометрические изменения, моторное поведение и выражение BDNF и его нормативного ncRNA в мозговой ткани крысиной модели обезвоживания. Это исследование охватывало четыре группы: контроль, один только Q10, демиелинация, вызванная кубическими зонами (DM), и DM + Q10 (n = 6 крыс/группа). Д

Совпадение в аннотации оригинала
Multiple sclerosis (MS) is a progressive neurodegenerative disorder. Limited data exist regarding the molecular mechanisms underlying cerebe … for 12 weeks. CoQ10 (200 mg/kg/day) was given by oral gavage, dissolved in 1% sodium carboxymethyl cellulose. Behavioral tests (rotarod, open field, and inverted grid) were conducted to assess motor function. Histological analysis and molecular evaluations were conducted to assess BDNF protein levels and the expression of MALAT1, HOTAIR (HOX Transcript Ant …

Scorpiones, Scolopendra and Gekko Inhibit Lung Cancer Growth and Metastasis by Ameliorating Hypoxic Tumor Microenvironment via PI3K/AKT/mTOR/HIF-1α Signaling Pathway.

OBJECTIVE: To investigate whether Buthus martensii karsch (Scorpiones), Scolopendra subspinipes mutilans L. Koch (Scolopendra) and Gekko gec … evelop lung cancer models, with rapamycin and cyclophosphamide as positive controls. Carboxy methyl cellulose solutions of Scorpiones, Scolopendra and Gekko were administered intragastrically as 0.33, 0.33, and 0.83 g/kg, respectively once daily for 21 days. Fluorescent expression were detected every 7 days after inoculation, and tumor growth curves were pl …

CMC/Gel/GO 3D-printed cardiac patches: GO and CMC improve flexibility and promote H9C2 cell proliferation, while EDC/NHS enhances stability.

In this research, carboxymethyl cellulose (CMC)/gelatin (Gel)/graphene oxide (GO)-based scaffolds were produced by using extrusion-based 3D printing for cardiac tissue regeneration. Rheological studies were conducted to evaluate the printability of CMC/Gel/GO inks, which revealed that CMC increased viscosity and enhanced printability. The 3D-printed cardiac patches were crosslinked with N-(3-dimethylaminopropyl)-n'-ethylcarbodiimide hydrochloride (EDC)/N-hydroxysuccinimide (NHS) (100:20 mM, 50:10 mM, 25:5 mM) and then characterized by mechanical analysis, electrical conductivity testing, conta…

Antiplatelet Effects of a Combination of Sappan Wood (Caesalpinia sappan L.) and Red Ginger (Zingiber officinale var. Rubrum) Extracts in a High-Fat Diet-Induced Rat Model.

Background: Antithrombotic medications, including antiplatelet agents, are standard treatments for patients with hyperlipidemia who have a h … an HFD for 8 weeks. In the eighth week, the control and negative groups were given carboxyl methyl cellulose (CMC) 0.5%, the positive control group was administered aspirin, and the other three groups were administered the combination extract of sappan wood and red ginger at various doses for 2 weeks. Blood samples were collected to assess the levels of hy …

[Clinical analysis of 4 children with cryptogenic organizing pneumonia].

Objective: To analyze the clinical features of children with cryptogenic organizing pneumonia (COP) confirmed by pathology. Methods: The cli … gn". All the 4 cases were performed thoracoscopic lung biopsy, and the pathological findings showed cellulose exudate or small nodules filled with granulation tissue or fibroblasts in the alveolar cavity and small airways, and 1 case was Masson corpuscle positive. Three patients achieved remission after glucocorticoid therapy. Spontaneous remission without …

Impression cytology of ocular surface in xeroderma pigmentosum.

PURPOSE: To describe cellular alterations detected by impression cytology of the ocular surface in patients with xeroderma pigmentosum. The secondary objective was to assess the reliability of impression cytology in diagnosing ocular surface squamous neoplasia. METHODS: Patients with xeroderma pigmentosum underwent a single-day complete ophthalmological examination and impression cytology for ocular surface evaluation using 13 mm diameter mixed cellulose esters membrane filters and combined staining with Periodic Acid Schiff, Hematoxylin and Eosin, and Papanicolaou stains followed by microsco…

Physicochemical Properties and Hypolipidemic Activity of Dietary Fiber from Rice Bran Meal Obtained by Three Oil-Production Methods.

This study investigated the effects of three oil production methods on the physicochemical properties of dietary fiber from rice bran flour, … ad similar reactive groups, and X-ray diffraction (XRD) results indicated that all three RBDFs were cellulose type I crystals. The results of thermogravimetric analysis showed that the lignin content of N-RBDF was significantly lower than that of the other two. Among the three kinds of RBDFs, E-RBDF had higher water retention capacity, swelling capacity, oi …