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Deep Learning-Derived Quantitative Scores for Chronic Rhinosinusitis Assessment: Correlation With Quality of Life Outcomes.

BackgroundComputed tomography (CT) plays a crucial role in assessing chronic rhinosinusitis, but lacks objective quantifiable indicators.ObjectiveThis study aimed to use deep learning for automated sinus segmentation to generate distinct quantitative scores and explore their correlations with disease-specific quality of life.MethodsFrom July 2021 to August 2022, 445 CT data were collected from 2 medical centers. A deep learning model based on nnU-Net was trained for automatic sinus segmentation and internally validated using 300 cases. The remaining 145 cases were split into an external testin…

Patient's Perspective and Change in Quality of Life After Stapes Surgery: A Multicenter Prospective Trial.

OBJECTIVE: This study evaluated outcomes of stapes surgery in otosclerosis patients by assessing audiometric results and health-related quality of life (HRQOL) using the Dutch Stapesplasty Outcome Test-25 (SPOT-25) questionnaire. Additionally, the role of SPOT-25 in preoperative decision-making and as a follow-up tool was explored. STUDY DESIGN: A prospective, multicenter cohort study. SETTING: One tertiary academic medical center and 3 secondary referral centers. METHODS: Data from 115 adult patients undergoing primary stapes surgery was analyzed. Audiometric outcomes were measured using p…

Psychopathologies and quality of life in mental and functional disorders associated with persistent somatic symptoms.

BACKGROUND: Persistent somatic symptoms (PSS) are a central diagnostic feature of several mental and functional disorders. However, only several studies simultaneously considered disorders from different systems. The purpose of this study was to explore the coexisting status of these diagnoses and to analyze the relationship between diagnoses and various psychopathologies, as well as quality of life (QOL). METHODS: We recruited participants from psychosomatic clinics and neighboring communities of a hospital. All individuals underwent semi-structured interviews covering functional and mental …

Highlighting the Psychiatric Burden: Depression and Anxiety Drive Poor Quality of Life in Focal Dystonia.

INTRODUCTION: Primary focal dystonias are movement disorders linked to dysfunctions in the basal ganglia, which also play a role in neuropsychiatric conditions. While motor symptoms in dystonia are well-documented, the neuropsychiatric comorbidities associated with these disorders, particularly depression, anxiety, obsessive-compulsive disorder (OCD), psychosis and pain, have been little explored. This study aims to assess the prevalence of these psychiatric disorders and their impact on the quality of life (QoL) in patients with cervical dystonia (CD) and oromandibular dystonia (OMD). METHOD…

Total Thyroidectomy and Quality of Life in Patients With Hashimoto Thyroiditis: A Systematic Scoping Review.

INTRODUCTION: Hashimoto thyroiditis is one of the most common causes of hypothyroidism globally. Patients frequently experience symptoms of hypothyroidism, for which the current mainstay of treatment is thyroid hormone repletion with levothyroxine. Despite treatment, some patients who achieve biochemical euthyroid status experience persistent hypothyroid symptoms for which there is no clear treatment. However, recent evidence indicates that total thyroidectomy may improve quality of life (QoL) in this group of patients. This review aims to understand the current literature on how total thyroid…

Correlation between fatigue and quality of life among patients with neuromyelitis optica in West China.

OBJECTIVE: To investigate the current status and determinants of fatigue and to examine the relationship between fatigue and quality of life (QOL) in patients with neuromyelitis optica (NMO). METHODS: Eligible patients with NMO were assessed with the Fatigue Impact Scale (FIS) and the Chinese version of the Multiple Sclerosis Quality of Life-54 (MSQOL-54). Clinical factors influencing fatigue were explored and the association between fatigue and QOL was analyzed. RESULTS: Sixty-nine patients (mean age 40.13 years, male/female 6/63) were enrolled. The median Expanded Disability Status Scale (…

Недостаток голоса, усталость голоса и качество голосовой жизни у пациентов с множественным склерозом.

ЦЕЛЬ: Описывать социально-демографические характеристики лиц с множественным склерозом и коррелировать и сравнивать усталость голоса, расстройства голоса и качество голосовой жизни людей с болезнью и без нее. МЕТОДЫ: Сквозное, количественное исследование 52 Добровольцы с множественным склерозом 52 - контроль за добровольцами в разбивке по полу, возрасту и уровню образования. Социально-демографические и клинические данные собирались с помощью вопросника и анализа медицинских записей. Участники отреагировали на сокращенный индекс инвалидности голоса ( " Voice Disability Index " )VHI-10

Совпадение в аннотации оригинала
PURPOSE: to describe sociodemographic characteristics of individuals with multiple sclerosis and correlate and compare vocal fatigue, voice handicap, and voice-related quality of life of individuals with and without the disease. METHODS: Cross-sectional, quantitative study with 52 volunteers with multiple sclerosis and 52 control volunteers, matched by sex,…

Сексуальное поведение, физическая активность и связанное со здоровьем качество жизни у взрослых с множественным склерозом.

ЦЕЛЬ: Мы изучили оседлое поведение как корреляцию связанных со здоровьем качества жизни (HRQOL) в множестве склерозов (MS), в то время как в этом перекрестном исследовании были учтены уровни физической активности. МАТЕРИАЛЫ И МЕТОДЫ: Участники с MS (N = 233) носили акселерометр, который измерял время, затрачиваемое в день на сидячее поведение, легкую физическую активность (LPA) и умеренно-вигорную физическую активность (MVPA), и завершил 29-разрядную шкалу воздействия склероза (MSIS-29) для физического и психологического HRQOL. Результаты: Не было никаких основных последствий оседлого поведени

Совпадение в аннотации оригинала
PURPOSE: We examined sedentary behavior as a correlate of health-related quality of life (HRQOL) in multiple sclerosis (MS), while accounting for levels of physical activity in this cross-sectional study. MATERIALS AND METHODS: Participants with MS (N = 233) wore an accelerometer, which measured time spent per day of sedentary behavior, light physical activ…

Quality of Life and Oral Function in Patients With Jaw Defects Following Oral Tumour Surgery.

OBJECTIVES: To evaluate various oral functions in patients with jaw defects after oral tumour surgery and to clarify factors associated with their quality of life (QoL). BACKGROUND: In patients with jaw defects, oral function and QoL are severely impaired. No studies have evaluated oral functions of patients with jaw defects and examined their relationships with QoL. MATERIALS AND METHODS: The study participants were 72 patients (mean age: 70.7 ± 10.1 years, range 48-93 years) who underwent prosthetic treatment with a removable denture to treat a jaw defect following oral tumour surgery. Mas…

Periodontitis and dental quality of life predict long-term survival in head and neck cancer.

BACKGROUND: Our aim was to investigate oral health in newly diagnosed head and neck squamous cell carcinoma (HNSCC) patients in relation to long-term survival. We assessed whether the level of alveolar bone loss due to periodontitis at diagnosis, measured from orthopantomogram (OPG), and reported dental health-related quality of life (HRQoL) scores obtained at diagnosis contain prognostic information for HNSCC patients. METHODS: A total of 79 patients from a consecutive cohort of 106 diagnosed with HNSCC between November 2002 and June 2005 were included. All patients reported dental HRQoL, OP…

Radiotherapy-Related Quality of Life in Nasopharyngeal Carcinoma Patients: A Systematic Review and Meta-Analysis.

INTRODUCTION: This systematic review and meta-analysis evaluated the quality of life (QoL) for nasopharyngeal carcinoma (NPC) patients with radiotherapy. METHODS: A systematic literature search was performed to identify relevant studies published until March 2022. Quality evaluation and data extraction were performed for the included studies, and meta-analysis was performed using Stata. RESULTS: Nine studies, including 1,659 patients, were eligible. Most QoL scales developed at the end of the treatment course and then followed by a gradual recovery to 1 year and more than 1 year after treatm…

Restless legs syndrome in patients with epilepsy: risk analysis, polysomnography, and quality of life evaluation.

STUDY OBJECTIVES: Restless legs syndrome (RLS) is a circadian rhythm related sensorimotor disorder due to brain iron deficiency, with lesion … seizures (OR 4.960, p = 0.005). Sleep parameters were not significantly associated with RLS status. Quality of life was significantly impaired in the group with RLS in both the physical and mental domains. CONCLUSIONS: Refractory epilepsy and nocturnal seizures were strongly correlated with RLS in patients with epilepsy. RLS should be considered a predictable co …

Walking as a Mediator Between Strength and Health-Related Quality of Life in Multiple Sclerosis.

UNLABELLED: Background and Purpose: Lower limb (LL) weakness and gait impairment are prevalent among persons with multiple sclerosis (PwMS) and can impede functional independence and impact health-related quality of life (HR-QoL). The purpose of this study was to examine the mediation effect of walking speed and perceived walking ability on the relationship between LL weakness and HR-QoL in ambulatory PwMS. METHODS: Participants (n = 175) were PwMS in this secondary analysis of a cross-sectional study. Demographics, pain (visual analog scale), fatigue (5-item Modified Fatigue Impact Scale), L…

Health-Related Quality of Life Among Iranian Women With Uterine Fibroids: A Cross Sectional Study.

OBJECTIVE: Uterine fibroids (UFs) are the most common benign tumors in women, and their prevalence varies between 5.4 and 77.0% in reproductive-aged women. Patients with UFs may experience severe symptoms that they can affect different aspects of their lives, including quality of life. This study aimed to investigate the health-related quality of life among Iranian women with UFs. MATERIALS AND METHODS: This cross-sectional study was conducted at Imam Hossein Hospital, Tehran, Iran, between November 2023 and February 2024, Data collection was based on the census method. Uterine Fibroid Sympto…

Long-term mental and physical quality of life outcomes following ileal pouch anal anastomosis surgery.

INTRODUCTION: This study presents the authors' experience over 14 years of performing restorative procto-colectomy with ileal pouch anal anastomosis (IPAA). The aim was to study the long-term quality of life outcomes and analyse the predictors of pouch function as well as physical and mental wellbeing. METHODS: This is a single-centre retrospective study conducted in a specialised colorectal surgery unit in the UK. The study included patients who underwent two- or three-staged panproctocolectomy with defunctioning ileostomy for ulcerative colitis (UC) or familial adenomatous polyposis between…

Health-related quality of life in patients with Waldenström macroglobulinemia: results from the ASPEN trial.

Aim ASPEN is a randomized, open-label, Phase III study comparing zanubrutinib and ibrutinib in patients with Waldenström macroglobulinemia ( … .Conclusion: Treatment with zanubrutinib was associated with greater improvements in health-related quality of life compared with ibrutinib in patients with WM and MYD88 mutations.Clinical Trial Registration: NCT03053440 (ClinicalTrials.gov).

Predicting Quality of Life in Parkinson's Disease: A Machine Learning Approach Employing Common Clinical Variables.

Background: Parkinson's Disease significantly impacts health-related quality of life, with the Parkinson's Disease Questionnaire-39 extensively used for its assessment. However, predicting such outcomes remains a challenge due to the subjective nature and variability in patient experiences. This study develops a machine learning model using accessible clinical data to enable predictions of life-quality outcomes in Parkinson's Disease and utilizes explainable machine learning techniques to identify key influencing factors, offering actionable insights for clinicians. Methods: Data from the Park…

Exploring the Relationship between Smartphone Addiction, Quality of Life, and Personality Traits in University Students.

Objective: This study aimed to explore the dynamics of the relationship among smartphone addiction, quality of life, and personality characteristics in university students. Method : This correlational and descriptive research was conducted to investigate the relationship between smartphone addiction, quality of life, and personality traits among university students. Using a nonprobability random sampling method, 496 university students were selected. Data collection involved the Student Information Form, Smartphone Addiction Scale, Symptom Checklist (SCL-90-R), Revised Eysenck Personality Ques…

Surveillance Compliance and Quality of Life Assessment Among Surgical Patients with Familial Adenomatous Polyposis Syndrome.

BACKGROUND: Familial adenomatous polyposis (FAP) syndrome has a near-100% lifetime risk of colorectal cancer. Early surveillance and prophylactic surgery have been advocated to reduce this risk. However, the surveillance practices among FAP individuals in Saudi Arabia are unknown. We aimed to explore surveillance compliance in our population, as well as the disease impact on their quality of life (QoL). METHODS: All patients with FAP who underwent surgical resection at King Saud University Medical City between 2016 and 2022 were included. Demographic data, clinical features, family history, a…